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PDBsum entry 3qi9

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protein ligands metals Protein-protein interface(s) links
Immune system PDB id
3qi9

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
290 a.a.
99 a.a.
196 a.a.
239 a.a.
Ligands
NAG-NAG
NAG ×2
PII
GOL ×2
Metals
_MG
Waters ×180
PDB id:
3qi9
Name: Immune system
Title: Crystal structure of mouse cd1d-alpha-phosphotidylinositol with mouse valpha14-vbeta6 2a3-d nkt tcr
Structure: Antigen-presenting glycoprotein cd1d1. Chain: a. Fragment: residues in unp 19-297. Engineered: yes. Beta-2-microglobulin. Chain: b. Engineered: yes. Nkt tcr v alpha 14. Chain: c.
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1d1, cd1.1. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: hi 5. Gene: b2m. Expressed in: escherichia coli.
Resolution:
2.30Å     R-factor:   0.248     R-free:   0.275
Authors: A.J.Clarke,J.Rossjohn
Key ref: T.Mallevaey et al. (2011). A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity, 34, 315-326. PubMed id: 21376640
Date:
26-Jan-11     Release date:   15-Feb-12    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus
Seq:
Struc:
336 a.a.
290 a.a.*
Protein chain
Pfam   ArchSchema ?
P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus
Seq:
Struc:
119 a.a.
99 a.a.
Protein chain
No UniProt id for this chain
Struc: 196 a.a.
Protein chain
No UniProt id for this chain
Struc: 239 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 17 residue positions (black crosses)

 

 
Immunity 34:315-326 (2011)
PubMed id: 21376640  
 
 
A molecular basis for NKT cell recognition of CD1d-self-antigen.
T.Mallevaey, A.J.Clarke, J.P.Scott-Browne, M.H.Young, L.C.Roisman, D.G.Pellicci, O.Patel, J.P.Vivian, J.L.Matsuda, J.McCluskey, D.I.Godfrey, P.Marrack, J.Rossjohn, L.Gapin.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23334244 P.J.Brennan, M.Brigl, and M.B.Brenner (2013).
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions.
  Nat Rev Immunol, 13, 101-117.  
23154222 J.Rossjohn, D.G.Pellicci, O.Patel, L.Gapin, and D.I.Godfrey (2012).
Recognition of CD1d-restricted antigens by natural killer T cells.
  Nat Rev Immunol, 12, 845-857.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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