PDBsum entry 3qgu

Transferase

PDB id: 3qgu

Contents

Protein chains

406 a.a.

Ligands

SO4 ×4

GOL ×2

AZI ×3

Waters ×888

PDB id:

3qgu

Name:

Transferase

Title:

L,l-diaminopimelate aminotransferase from chlamydomonas reinhardtii

Structure:

Ll-diaminopimelate aminotransferase. Chain: a, b. Engineered: yes

Source:

Chlamydomonas reinhardtii. Organism_taxid: 3055. Gene: dpa1. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.55Å R-factor: 0.126 R-free: 0.171

Authors:

R.C.J.Dobson,I.Giron,A.O.Hudson

Key ref:

R.C.Dobson et al. (2011). L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. Plos One, 6, e20439. PubMed id: 21633707

Date:

25-Jan-11 Release date: 01-Jun-11

Protein chains

A8IW39  (A8IW39_CHLRE) -  Aminotransferase class I/classII domain-containing protein from Chlamydomonas reinhardtii

Seq: 441 a.a.

Struc: 406 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.6.1.83 - LL-diaminopimelate aminotransferase.
• Reaction: (2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + L-glutamate + H2O + H⁺

(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate (Bound ligand (Het Group name = GOL) matches with 45.45% similarity) = (S)-2,3,4,5- tetrahydrodipicolinate + L-glutamate + H2O + H(+)

• Cofactor: Pyridoxal 5'-phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Plos One 6:e20439 (2011)

PubMed id: 21633707

L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development.

R.C.Dobson, I.Girón, A.O.Hudson.

ABSTRACT

No abstract given.