PDBsum entry 3qe1

Protein binding

PDB id: 3qe1

Contents

Protein chain

102 a.a.

Waters ×120

PDB id:

3qe1

Name:

Protein binding

Title:

Crystal structure of pdz domain of sorting nexin 27 (snx27) fused to thE C-terminal residues (eseskv) of girk3

Structure:

Sorting nexin-27, g protein-activated inward rectifier potassium channel 3 chimera. Chain: a. Fragment: pdz domain (unp residues 39-133), girk-3 c-terminus (unp residues 388-393). Synonym: snx27, map-responsive gene protein, methamphetamine- responsive transcript 1 protein, pdz-protein mrt1, girk-3, inward rectifier k(+) channel kir3.3, potassium channel, inwardly rectifying subfamily j member 9.

Source:

Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: mrt1, kcnj9. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.68Å R-factor: 0.161 R-free: 0.223

Authors:

B.Balana,W.Kwiatkowski,S.Choe

Key ref:

B.Balana et al. (2011). Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27. Proc Natl Acad Sci U S A, 108, 5831-5836. PubMed id: 21422294

Date:

19-Jan-11 Release date: 16-Mar-11

Protein chain

Q63511  (KCNJ9_RAT) -  G protein-activated inward rectifier potassium channel 3 from Rattus norvegicus

Seq: 393 a.a.

Struc: 102 a.a.*

Protein chain

Q8K4V4  (SNX27_RAT) -  Sorting nexin-27 from Rattus norvegicus

Seq: 539 a.a.

Struc: 102 a.a.*

* PDB and UniProt seqs differ at 89 residue positions (black crosses)

Proc Natl Acad Sci U S A 108:5831-5836 (2011)

PubMed id: 21422294

Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.

B.Balana, I.Maslennikov, W.Kwiatkowski, K.M.Stern, L.Bahima, S.Choe, P.A.Slesinger.

ABSTRACT

No abstract given.