PDBsum entry 3pv6

Immune system

PDB id: 3pv6

Contents

Protein chains

214 a.a.

112 a.a.

Ligands

NAG-NAG

NAG ×2

Waters ×15

PDB id:

3pv6

Name:

Immune system

Title:

Crystal structure of nkp30 bound to its ligand b7-h6

Structure:

Ig-like domain-containing protein dkfzp686o24166/dkfzp686i21167. Chain: a. Fragment: unp residues 25-262. Synonym: b7-h6. Engineered: yes. Natural cytotoxicity triggering receptor 3. Chain: b. Fragment: unp residues 19-135.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sp9. Gene: ncr3, 1c7, ly117. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.30Å R-factor: 0.239 R-free: 0.289

Authors:

Y.Li

Key ref:

Y.Li et al. Structure of the activating natural killer cell recep nkp30 bound to its ligand b7-H6 reveals basis for tum recognition in humans. To be published, .

Date:

06-Dec-10 Release date: 16-Mar-11

Protein chain

Q68D85  (NR3L1_HUMAN) -  Natural cytotoxicity triggering receptor 3 ligand 1 from Homo sapiens

Seq: 454 a.a.

Struc: 214 a.a.*

Protein chain

O14931  (NCTR3_HUMAN) -  Natural cytotoxicity triggering receptor 3 from Homo sapiens

Seq: 201 a.a.

Struc: 112 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)