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PDBsum entry 3psl
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Transcription/transcription inhibitor
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PDB id
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3psl
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Transcription/transcription inhibitor
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Title:
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Fine-tuning the stimulation of mll1 methyltransferase activity by a histone h3 based peptide mimetic
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Structure:
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Wd repeat-containing protein 5. Chain: a, b. Fragment: wdr5 (unp residues 21-334). Synonym: bmp2-induced 3-kb gene protein. Engineered: yes. N-alpha acetylated form of histone h3. Chain: c, d. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: wdr5, big3. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: n-alpha acetylated form of histone h3 (synthetic)
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Resolution:
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1.70Å
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R-factor:
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0.157
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R-free:
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0.205
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Authors:
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V.Avdic,P.Zhang,S.Lanouette,A.Voronova,I.Skerjanc,J.-F.Couture
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Key ref:
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V.Avdic
et al.
(2011).
Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.
Faseb J,
25,
960-967.
PubMed id:
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Date:
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01-Dec-10
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Release date:
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22-Dec-10
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PROCHECK
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Headers
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References
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P61964
(WDR5_HUMAN) -
WD repeat-containing protein 5 from Homo sapiens
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Seq:
Struc:
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334 a.a.
298 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Faseb J
25:960-967
(2011)
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PubMed id:
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Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.
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V.Avdic,
P.Zhang,
S.Lanouette,
A.Voronova,
I.Skerjanc,
J.F.Couture.
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ABSTRACT
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Links
