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PDBsum entry 3ppy
Go to PDB code:
Cell adhesion
PDB id
3ppy
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Contents
Protein chain
187 a.a.
Metals
_NA
Waters
×157
PDB id:
3ppy
Links
PDBe
RCSB
MMDB
JenaLib
Proteopedia
CATH
SCOP
PDBSWS
PDBePISA
ProSAT
Name:
Cell adhesion
Title:
Crystal structure of the d1596a/n1602a double mutant of an engineered vwf a2 domain (n1493c and c1670s)
Structure:
Von willebrand factor. Chain: a. Fragment: vwf a2 domain, unp residues 1488-1674. Synonym: vwf, von willebrand antigen 2, von willebrand antigen ii. Engineered: yes. Mutation: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: f8vwf, vwf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.00Å
R-factor:
0.203
R-free:
0.232
Authors:
M.Zhou,X.Dong,C.Zhong,J.Ding
Key ref:
M.Zhou et al. (2011). A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13.
Blood
,
117
, 4623-4631.
PubMed id:
21385852
Date:
25-Nov-10
Release date:
04-May-11
PROCHECK
Headers
References
Protein chain
?
P04275
(VWF_HUMAN) - von Willebrand factor from Homo sapiens
Seq:
Struc:
Seq:
Struc:
Seq:
Struc:
Seq:
Struc:
Seq:
Struc:
Seq:
Struc:
2813 a.a.
187 a.a.
*
Key:
PfamA domain
Secondary structure
CATH domain
*
PDB and UniProt seqs differ at 5 residue positions (black crosses)
Blood
117
:4623-4631 (2011)
PubMed id:
21385852
A novel calcium-binding site of von Willebrand factor A2 domain regulates its cleavage by ADAMTS13.
M.Zhou,
X.Dong,
C.Baldauf,
H.Chen,
Y.Zhou,
T.A.Springer,
X.Luo,
C.Zhong,
F.Gräter,
J.Ding.
ABSTRACT
No abstract given.
Links
