PDBsum entry 3pp3

Immune system

PDB id: 3pp3

Contents

Protein chains

220 a.a.

219 a.a.

Waters ×527

PDB id:

3pp3

Name:

Immune system

Title:

Epitope characterization and crystal structure of ga101 provide insights into the molecular basis for the type i / type ii distinction of anti- cd20 antibodies

Structure:

Ga101 fab heavy chain. Chain: h, i. Engineered: yes. Ga101 fab light chain. Chain: l, k. Engineered: yes

Source:

Mus musculus. Organism_taxid: 10090. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: chinese hamster ovary (cho). Expression_system_cell_line: chinese hamster ovary (cho)

Resolution:

2.51Å R-factor: 0.210 R-free: 0.269

Authors:

K.-P.Hopfner,A.Lammens

Key ref:

G.Niederfellner et al. (2011). Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies. Blood, 118, 358-367. PubMed id: 21444918

Date:

24-Nov-10 Release date: 13-Apr-11

Protein chains

No UniProt id for this chain

Struc: 220 a.a.

Protein chains

No UniProt id for this chain

Struc: 219 a.a.

Blood 118:358-367 (2011)

PubMed id: 21444918

Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.

G.Niederfellner, A.Lammens, O.Mundigl, G.J.Georges, W.Schaefer, M.Schwaiger, A.Franke, K.Wiechmann, S.Jenewein, J.W.Slootstra, P.Timmerman, A.Brännström, F.Lindstrom, E.Mössner, P.Umana, K.P.Hopfner, C.Klein.

ABSTRACT

No abstract given.