PDBsum entry 3pof

Hydrolase

PDB id: 3pof

Contents

Protein chains

113 a.a.

Ligands

SO4 ×2

TRS

Metals

_CA ×2

Waters ×251

PDB id:

3pof

Name:

Hydrolase

Title:

Crystal structure of masp-1 cub2 domain bound to ca2+

Structure:

Mannan-binding lectin serine protease 1. Chain: a, b. Fragment: masp-1 cub2 domain (unp residues 188-301). Synonym: complement factor masp-3, complement-activating component of ra-reactive factor, mannose-binding lectin-associated serine protease 1, masp-1, mannose-binding protein-associated serine protease, ra- reactive factor serine protease p100, rarf, serine protease 5, mannan-binding lectin serine protease 1 heavy chain, mannan-binding lectin serine protease 1 light chain.

Source:

Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: crarf, masp-1, masp1, masp3. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.50Å R-factor: 0.119 R-free: 0.149

Authors:

A.R.Gingras,P.C.E.Moody,R.Wallis

Key ref:

A.R.Gingras et al. (2011). Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation. Structure, 19, 1635-1643. PubMed id: 22078562

Date:

22-Nov-10 Release date: 24-Aug-11

Protein chains

Q8CHN8  (MASP1_RAT) -  Mannan-binding lectin serine protease 1 from Rattus norvegicus

Seq: 704 a.a.

Struc: 113 a.a.

Enzyme reactions

• Enzyme class: E.C.3.4.21.- - ?????

Structure 19:1635-1643 (2011)

PubMed id: 22078562

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation.

A.R.Gingras, U.V.Girija, A.H.Keeble, R.Panchal, D.A.Mitchell, P.C.Moody, R.Wallis.

ABSTRACT

No abstract given.