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PDBsum entry 3pew
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Hydrolase/RNA
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PDB id
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3pew
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PDB id:
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| Name: |
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Hydrolase/RNA
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Title:
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S. Cerevisiae dbp5 l327v bound to RNA and adp bef3
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Structure:
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Atp-dependent RNA helicase dbp5. Chain: a. Synonym: dead box protein 5, helicase ca5/6, ribonucleic acid- trafficking protein 8. Engineered: yes. Mutation: yes. RNA (5'-r(p Up Up Up Up Up U)-3'). Chain: b. Engineered: yes
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Source:
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Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: dbp5, rat8, yor046c. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
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Resolution:
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1.50Å
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R-factor:
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0.166
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R-free:
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0.189
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Authors:
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B.Montpetit,N.D.Thomsen,K.J.Helmke,M.A.Seeliger,J.M.Berger,K.Weis
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Key ref:
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B.Montpetit
et al.
(2011).
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
Nature,
472,
238-242.
PubMed id:
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Date:
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27-Oct-10
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Release date:
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23-Mar-11
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PROCHECK
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Headers
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References
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P20449
(DBP5_YEAST) -
ATP-dependent RNA helicase DBP5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
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Seq:
Struc:
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482 a.a.
391 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class:
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E.C.3.6.4.13
- Rna helicase.
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Reaction:
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ATP + H2O = ADP + phosphate + H+
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ATP
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+
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H2O
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=
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ADP
Bound ligand (Het Group name = )
corresponds exactly
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+
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phosphate
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Nature
472:238-242
(2011)
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PubMed id:
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A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export.
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B.Montpetit,
N.D.Thomsen,
K.J.Helmke,
M.A.Seeliger,
J.M.Berger,
K.Weis.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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I.Barbosa,
N.Haque,
F.Fiorini,
C.Barrandon,
C.Tomasetto,
M.Blanchette,
and
H.Le Hir
(2012).
Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly.
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Nat Struct Mol Biol,
19,
983-990.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
