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PDBsum entry 3p30
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Immune system
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PDB id
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3p30
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Contents |
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84 a.a.
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211 a.a.
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226 a.a.
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* Residue conservation analysis
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PDB id:
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| Name: |
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Immune system
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Title:
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Crystal structure of the cluster ii fab 1281 in complex with HIV-1 gp41 ectodomain
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Structure:
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HIV-1 gp41. Chain: a. Engineered: yes. 1281 fab light chain. Chain: l. Engineered: yes. 1281 fab heavy chain. Chain: h. Engineered: yes
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Source:
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Human immunodeficiency virus 1. Organism_taxid: 11676. Gene: HIV-1 env. Expressed in: escherichia coli. Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens.
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Resolution:
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3.30Å
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R-factor:
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0.262
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R-free:
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0.289
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Authors:
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G.Frey,J.Chen,S.Rits-Volloch,M.M.Freeman,S.Zolla-Pazner,B.Chen
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Key ref:
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G.Frey
et al.
(2010).
Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Nat Struct Biol,
17,
1486-1491.
PubMed id:
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Date:
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04-Oct-10
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Release date:
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17-Nov-10
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PROCHECK
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Headers
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References
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No UniProt id for this chain
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Nat Struct Biol
17:1486-1491
(2010)
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PubMed id:
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Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
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G.Frey,
J.Chen,
S.Rits-Volloch,
M.M.Freeman,
S.Zolla-Pazner,
B.Chen.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.R.Ruprecht,
A.Krarup,
L.Reynell,
A.M.Mann,
O.F.Brandenberg,
L.Berlinger,
I.A.Abela,
R.R.Regoes,
H.F.Günthard,
P.Rusert,
and
A.Trkola
(2011).
MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1.
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J Exp Med,
208,
439-454.
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M.J.McElrath
(2011).
Standing guard at the mucosa.
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Immunity,
34,
146-148.
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Z.Beck,
B.K.Brown,
G.R.Matyas,
V.R.Polonis,
M.Rao,
and
C.R.Alving
(2011).
Infection of human peripheral blood mononuclear cells by erythrocyte-bound HIV-1: effects of antibodies and complement.
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Virology,
412,
441-447.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
