PDBsum entry 3oqs

Protein transport

PDB id: 3oqs

Contents

Protein chain

425 a.a.

Ligands

VAL-ALA-LYS-LYS-TYR-ARG-ASN

Waters ×359

PDB id:

3oqs

Name:

Protein transport

Title:

Crystal structure of importin-alpha bound to a clic4 nls peptide

Structure:

Peptide of chloride intracellular channel protein 4. Chain: b. Fragment: nls (nuclear localisation signal) unp residues 198-207. Synonym: intracellular chloride ion channel protein p64h1. Engineered: yes. Importin subunit alpha-2. Chain: a. Fragment: nls binding domain (unp residues 70-529). Synonym: karyopherin subunit alpha-2, srp1-alpha, rag cohort protein

Source:

Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: this sequence occurs naturally in humans.. Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2, rch1.

Resolution:

2.00Å R-factor: 0.199 R-free: 0.237

Authors:

A.V.Mynott,L.J.Brown,S.J.Harrop,P.M.G.Curmi

Key ref:

A.V.Mynott et al. (2011). Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4. Febs J, 278, 1662-1675. PubMed id: 21388519

Date:

03-Sep-10 Release date: 27-Jul-11

Protein chain

P52293  (IMA1_MOUSE) -  Importin subunit alpha-1 from Mus musculus

Seq: 529 a.a.

Struc: 425 a.a.

Febs J 278:1662-1675 (2011)

PubMed id: 21388519

Crystal structure of importin-α bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4.

A.V.Mynott, S.J.Harrop, L.J.Brown, S.N.Breit, B.Kobe, P.M.Curmi.

ABSTRACT

No abstract given.