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PDBsum entry 3oll

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protein ligands Protein-protein interface(s) links
Hormone receptor/activator PDB id
3oll
Jmol PyMol
Contents
Protein chains
235 a.a. *
Ligands
ARG-HIS-LYS-ILE-
LEU-HIS-ARG-LEU-
LEU-GLN
×2
EST ×2
Waters ×510
* Residue conservation analysis
PDB id:
3oll
Name: Hormone receptor/activator
Title: Crystal structure of phosphorylated estrogen receptor beta l binding domain
Structure: Estrogen receptor beta. Chain: a, b. Fragment: ligand binding domain (unp residues 261-500). Synonym: er-beta, nuclear receptor subfamily 3 group a memb engineered: yes. Nuclear receptor coactivator 1. Chain: c, d. Fragment: unp residues 683-701. Synonym: ncoa-1, steroid receptor coactivator 1, src-1, rip
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: esr2, estrb, nr3a2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
Resolution:
1.50Å     R-factor:   0.177     R-free:   0.208
Authors: S.Moecklinghoff,R.Rose,C.Ottmann,L.Brunsveld
Key ref: S.Möcklinghoff et al. (2010). Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain. Chembiochem, 11, 2251-2254. PubMed id: 20922740
Date:
26-Aug-10     Release date:   17-Nov-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q92731  (ESR2_HUMAN) -  Estrogen receptor beta
Seq:
Struc:
 
Seq:
Struc:
530 a.a.
235 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     nucleus   1 term 
  Biological process     steroid hormone mediated signaling pathway   2 terms 
  Biochemical function     DNA binding     3 terms  

 

 
Chembiochem 11:2251-2254 (2010)
PubMed id: 20922740  
 
 
Synthesis and crystal structure of a phosphorylated estrogen receptor ligand binding domain.
S.Möcklinghoff, R.Rose, M.Carraz, A.Visser, C.Ottmann, L.Brunsveld.
 
  ABSTRACT  
 
No abstract given.

 

 

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