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PDBsum entry 3okw

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
3okw

 

 

 

 

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Contents
Protein chains
540 a.a. *
Ligands
NAG-NAG ×4
NAG-NAG-BMA-MAN-
MAN
NAG ×2
CIT
GOL ×10
Waters ×278
* Residue conservation analysis
PDB id:
3okw
Name: Signaling protein
Title: Mouse semaphorin 6a, extracellular domains 1-2
Structure: Semaphorin-6a. Chain: a, b. Synonym: semaphorin via, sema via, semaphorin-6a-1, sema6a-1, semaphorin q, sema q. Engineered: yes
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: sema6a, semaq. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293.
Resolution:
2.30Å     R-factor:   0.186     R-free:   0.219
Authors: B.J.C.Janssen,R.A.Robinson,C.H.Bell,C.Siebold,E.Y.Jones
Key ref: B.J.Janssen et al. (2010). Structural basis of semaphorin-plexin signalling. Nature, 467, 1118-1122. PubMed id: 20877282
Date:
25-Aug-10     Release date:   13-Oct-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
O35464  (SEM6A_MOUSE) -  Semaphorin-6A from Mus musculus
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1031 a.a.
540 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
Nature 467:1118-1122 (2010)
PubMed id: 20877282  
 
 
Structural basis of semaphorin-plexin signalling.
B.J.Janssen, R.A.Robinson, F.Pérez-Brangulí, C.H.Bell, K.J.Mitchell, C.Siebold, E.Y.Jones.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23104057 B.J.Janssen, T.Malinauskas, G.A.Weir, M.Z.Cader, C.Siebold, and E.Y.Jones (2012).
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
  Nat Struct Mol Biol, 19, 1293-1299.
PDB codes: 4gz8 4gz9 4gza
22002224 M.Kim, Z.Y.Sun, K.D.Rand, X.Shi, L.Song, Y.Cheng, A.F.Fahmy, S.Majumdar, G.Ofek, Y.Yang, P.D.Kwong, J.H.Wang, J.R.Engen, G.Wagner, and E.L.Reinherz (2011).
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization.
  Nat Struct Mol Biol, 18, 1235-1243.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

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