spacer
spacer

PDBsum entry 3okt

Go to PDB code: 
protein ligands metals links
Signaling protein PDB id
3okt

 

 

 

 

Loading ...

 
JSmol PyMol  
Contents
Protein chain
656 a.a. *
Ligands
NAG ×5
GOL ×4
Metals
_CL ×2
_NA
Waters ×182
* Residue conservation analysis
PDB id:
3okt
Name: Signaling protein
Title: Mouse plexin a2, extracellular domains 1-4
Structure: Plexin-a2. Chain: a. Fragment: residues 33-703, extracellular domains 1-4. Synonym: plexin-2, plex 2. Engineered: yes
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: plxna2, kiaa0463. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293.
Resolution:
2.30Å     R-factor:   0.199     R-free:   0.251
Authors: B.J.C.Janssen,R.A.Robinson,C.H.Bell,C.Siebold,E.Y.Jones
Key ref: B.J.Janssen et al. (2010). Structural basis of semaphorin-plexin signalling. Nature, 467, 1118-1122. PubMed id: 20877282
Date:
25-Aug-10     Release date:   13-Oct-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
P70207  (PLXA2_MOUSE) -  Plexin-A2 from Mus musculus
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
 
Seq:
Struc:
1894 a.a.
656 a.a.
Key:    Secondary structure  CATH domain

 

 
Nature 467:1118-1122 (2010)
PubMed id: 20877282  
 
 
Structural basis of semaphorin-plexin signalling.
B.J.Janssen, R.A.Robinson, F.Pérez-Brangulí, C.H.Bell, K.J.Mitchell, C.Siebold, E.Y.Jones.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23104057 B.J.Janssen, T.Malinauskas, G.A.Weir, M.Z.Cader, C.Siebold, and E.Y.Jones (2012).
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
  Nat Struct Mol Biol, 19, 1293-1299.
PDB codes: 4gz8 4gz9 4gza
22002224 M.Kim, Z.Y.Sun, K.D.Rand, X.Shi, L.Song, Y.Cheng, A.F.Fahmy, S.Majumdar, G.Ofek, Y.Yang, P.D.Kwong, J.H.Wang, J.R.Engen, G.Wagner, and E.L.Reinherz (2011).
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization.
  Nat Struct Mol Biol, 18, 1235-1243.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.

 

spacer

spacer