PDBsum entry 3oed

Immune system

PDB id: 3oed

Contents

Protein chains

294 a.a.

130 a.a.

Waters ×16

PDB id:

3oed

Name:

Immune system

Title:

The structure of the complex between complement receptor cr2 and its ligand complement fragment c3d

Structure:

Complement c3. Chain: a, b. Fragment: c3 (unp residues 996-1303). Synonym: c3 and pzp-like alpha-2-macroglobulin domain-containing protein 1. Engineered: yes. Mutation: yes. Complement receptor type 2. Chain: c, d.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: c3, cpamd1. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: c3dr, cr2.

Resolution:

3.16Å R-factor: 0.189 R-free: 0.259

Authors:

D.E.Isenman,J.M.H.Van Den Elsen

Key ref:

J.M.van den Elsen and D.E.Isenman (2011). A crystal structure of the complex between human complement receptor 2 and its ligand C3d. Science, 332, 608-611. PubMed id: 21527715

Date:

12-Aug-10 Release date: 11-May-11

Protein chains

P01024  (CO3_HUMAN) -  Complement C3 from Homo sapiens

Seq: 1663 a.a.

Struc: 294 a.a.*

Protein chains

P20023  (CR2_HUMAN) -  Complement receptor type 2 from Homo sapiens

Seq: 1033 a.a.

Struc: 130 a.a.

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Science 332:608-611 (2011)

PubMed id: 21527715

A crystal structure of the complex between human complement receptor 2 and its ligand C3d.

J.M.van den Elsen, D.E.Isenman.

ABSTRACT

No abstract given.