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UniProt functional annotation for P27472 | ||
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| UniProt code: P27472. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen. |
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| Catalytic activity: | |
Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)- alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA- COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11; |
| Activity regulation: | |
Allosteric activation by glucose-6-phosphate, and phosphorylation by a cAMP-dependent kinase. |
| Pathway: | |
Glycan biosynthesis; glycogen biosynthesis. |
| Subunit: | |
Interacts with PCL10. {ECO:0000269|PubMed:10490639}. |
| Ptm: | |
Phosphorylated by the cyclin-CDK PCL10-PHO85. Phosphorylation causes inactivation of enzyme. {ECO:0000269|PubMed:9584169}. |
| Miscellaneous: | |
Present with 14600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the glycosyltransferase 3 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.