PDBsum entry 3n9g

Immune system

PDB id: 3n9g

Contents

Protein chains

230 a.a. *

220 a.a. *

Waters ×821

* Residue conservation analysis

PDB id:

3n9g

Name:

Immune system

Title:

Crystal structure of the fab fragment of the human neutralizing anti- west nile virus mab cr4354

Structure:

Fab fragment of mab cr4354, heavy chain. Chain: h. Engineered: yes. Fab fragment of mab cr4354, light chain. Chain: l. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.

Resolution:

1.43Å R-factor: 0.168 R-free: 0.186

Authors:

B.Kaufmann,M.G.Rossmann

Key ref:

B.Kaufmann et al. (2010). Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proc Natl Acad Sci U S A, 107, 18950-18955. PubMed id: 20956322

Date:

29-May-10 Release date: 24-Nov-10

Protein chain

No UniProt id for this chain

Struc: 230 a.a.

Protein chain

No UniProt id for this chain

Struc: 220 a.a.

Proc Natl Acad Sci U S A 107:18950-18955 (2010)

PubMed id: 20956322

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.

B.Kaufmann, M.R.Vogt, J.Goudsmit, H.A.Holdaway, A.A.Aksyuk, P.R.Chipman, R.J.Kuhn, M.S.Diamond, M.G.Rossmann.

ABSTRACT

No abstract given.