PDBsum entry 3n0d

Transcription

PDB id

3n0d

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Contents

			Protein chain

					315 a.a. *

			Waters ×172

* Residue conservation analysis

PDB id:

3n0d

Links

Name:

Transcription

Title:

Crystal structure of wdr5 mutant (w330f)

Structure:

Wd repeat-containing protein 5. Chain: a. Fragment: residues 31-334. Synonym: wdr5, bmp2-induced 3-kb gene protein. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.30Å

R-factor:

0.170

R-free:

0.233

Authors:

Y.-D.Wu,X.-H.Wu,Y.Gao,R.-C.Chen

Key ref:

X.H.Wu et al. (2010). The effect of Asp-His-Ser/Thr-Trp tetrad on the thermostability of WD40-repeat proteins. Biochemistry, 49, 10237-10245. PubMed id: 20939513

Date:

13-May-10

Release date:

20-Oct-10

PROCHECK

	Headers

	References

Protein chain

P61964 (WDR5_HUMAN) - WD repeat-containing protein 5 from Homo sapiens

Seq: Struc:					334 a.a. 315 a.a.*

Key:

PfamA domain

Secondary structure

CATH domain

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

	Biochemistry 49:10237-10245 (2010)
PubMed id: 20939513

The effect of Asp-His-Ser/Thr-Trp tetrad on the thermostability of WD40-repeat proteins.
X.H.Wu, R.C.Chen, Y.Gao, Y.D.Wu.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

21468892

C.Xu, and J.Min (2011).
Structure and function of WD40 domain proteins.

Protein Cell, 2, 202-214.

PDB codes:

3e0c 3fm0 3i2n 3ow8

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.