PDBsum entry 3mzh

Transcription/DNA

PDB id: 3mzh

Contents

Protein chains

225 a.a.

DNA/RNA

Ligands

CMP ×3

PDB id:

3mzh

Name:

Transcription/DNA

Title:

Crystal structure of camp receptor protein from mycobacterium tuberculosis in complex with camp and its DNA binding element

Structure:

Probable transcriptional regulatory protein (probably crp/fnr-family). Chain: a, b. Synonym: crp, transcriptional regulator, crp/fnr family. Engineered: yes. 5'-d(p Ap Ap Ap Tp Gp Tp Gp Ap Tp Cp Tp Ap Gp Gp Tp Cp Ap C p Gp Tp G)-3'. Chain: c. Engineered: yes.

Source:

Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: rv3676. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic: yes

Resolution:

2.90Å R-factor: 0.248 R-free: 0.279

Authors:

Y.Akhter,M.Wilmanns

Key ref:

Y.Akhter et al. Crystal structure of camp receptor protein from mycobacterium tuberculosis in complex with DNA and ca. To be published, .

Date:

12-May-10 Release date: 08-Jun-11

Protein chains

P9WMH3  (CRPL_MYCTU) -  CRP-like cAMP-activated global transcriptional regulator from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Seq: 224 a.a.

Struc: 225 a.a.

DNA/RNA chains

A-A-A-T-G-T-G-A-T-C-T-A-G-G-T-C-A-C-G-T-G 21 bases

C-A-C-G-T-G-A-C-C-T-A-G-A-T-C-A-C-A-T-C 20 bases