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PDBsum entry 3mse
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of c-terminal domain of pf110239.
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Structure:
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Calcium-dependent protein kinase, putative. Chain: b. Fragment: c-terminal domain of pf110239 (unp residues 1439:1617). Engineered: yes
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Source:
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Plasmodium falciparum. Organism_taxid: 5833. Gene: pf11_0239. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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2.10Å
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R-factor:
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0.224
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R-free:
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0.264
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Authors:
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A.K.Wernimont,J.D.Artz,A.Hutchinson,H.Sullivan,J.Weadge,W.Tempel, A.Bochkarev,C.H.Arrowsmith,A.M.Edwards,C.Bountra,J.Weigelt,R.Hui, Y.H.Lin,A.M.Neculai,M.Amani,Structural Genomics Consortium (Sgc)
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Key ref:
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A.K.Wernimont
et al.
Crystal structure of c-Terminal domain of pf110239. ( Target).
To be published,
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Date:
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29-Apr-10
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Release date:
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23-Jun-10
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PROCHECK
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Headers
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References
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Q8IID5
(Q8IID5_PLAF7) -
Calcium-dependent protein kinase 6 from Plasmodium falciparum (isolate 3D7)
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Seq:
Struc:
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1617 a.a.
168 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.11.17
- calcium/calmodulin-dependent protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Cofactor:
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Ca(2+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
