UniProt functional annotation for P43166

UniProt code: P43166.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Function: Reversible hydration of carbon dioxide.
Catalytic activity: H(2)CO(3) = CO(2) + H(2)O.
Cofactor: Zinc.
Enzyme regulation: Activated by histamine, L-adrenaline, L- and D- histidine, and L- and D-phenylalanine. Inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA), by saccharin and Foscarnet (phosphonoformate trisodium salt).
Subcellular location: Cytoplasm (Probable).
Similarity: Belongs to the alpha-carbonic anhydrase family.

Annotations taken from UniProtKB at the EBI.