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PDBsum entry 3ma9

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protein metals Protein-protein interface(s) links
Immune system PDB id
3ma9

 

 

 

 

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Contents
Protein chains
197 a.a. *
214 a.a. *
209 a.a. *
Metals
_NA ×2
Waters ×442
* Residue conservation analysis
PDB id:
3ma9
Name: Immune system
Title: Crystal structure of gp41 derived protein complexed with fab 8066
Structure: Transmembrane glycoprotein. Chain: a. Synonym: gp41. Engineered: yes. Fab8066 fab antibody fragment, heavy chain. Chain: h. Engineered: yes. Fab8066 fab antibody fragment, light chain. Chain: l.
Source: Human immunodeficiency virus 1. Organism_taxid: 11676. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Organism_taxid: 9606
Resolution:
2.05Å     R-factor:   0.194     R-free:   0.245
Authors: M.Li,E.Gustchina,J.Louis,A.Gustchina,A.Wlodawer,M.Clore
Key ref: E.Gustchina et al. (2010). Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41. Plos Pathog, 6, e1001182. PubMed id: 21085615
Date:
23-Mar-10     Release date:   01-Dec-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
D0VWW0  (D0VWW0_9HIV1) -  Transmembrane glycoprotein from Human immunodeficiency virus 1
Seq:
Struc:
226 a.a.
197 a.a.
Protein chain
No UniProt id for this chain
Struc: 214 a.a.
Protein chain
No UniProt id for this chain
Struc: 209 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 

 
Plos Pathog 6:e1001182 (2010)
PubMed id: 21085615  
 
 
Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.
E.Gustchina, M.Li, J.M.Louis, D.E.Anderson, J.Lloyd, C.Frisch, C.A.Bewley, A.Gustchina, A.Wlodawer, G.M.Clore.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
22932267 D.Lingwood, P.M.McTamney, H.M.Yassine, J.R.Whittle, X.Guo, J.C.Boyington, C.J.Wei, and G.J.Nabel (2012).
Structural and genetic basis for development of broadly neutralizing influenza antibodies.
  Nature, 489, 566-570.
PDB code: 4evn
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.

 

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