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UniProt functional annotation for Q9NVP1 | ||
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| UniProt code: Q9NVP1. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Probable RNA-dependent helicase. |
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| Catalytic activity: | |
Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
| Subunit: | |
Interacts with NOL8; the interaction is RNA-dependent. {ECO:0000269|PubMed:16963496, ECO:0000269|PubMed:20941364}. |
| Subcellular location: | |
Nucleus, nucleolus {ECO:0000269|PubMed:16963496}. Chromosome {ECO:0000269|PubMed:20813266}. |
| Similarity: | |
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. {ECO:0000305}. |
| Sequence caution: | |
Sequence=CAA67295.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.