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PDBsum entry 3lm0
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of human serine/threonine kinase 17b (stk17b)
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Structure:
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Serine/threonine-protein kinase 17b. Chain: a. Synonym: dap kinase-related apoptosis-inducing protein kinase 2. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: drak2, stk17b. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.35Å
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R-factor:
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0.206
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R-free:
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0.267
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Authors:
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E.Ugochukwu,M.Soundararajan,P.Rellos,O.Fedorov,C.Phillips,J.Wang, E.Hapka,P.Filippakopoulos,A.Chaikuad,A.C.W.Pike,F.Von Delft, C.Bountra,C.H.Arrowsmith,J.Weigelt,A.Edwards,S.Knapp,Structural Genomics Consortium (Sgc)
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Date:
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29-Jan-10
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Release date:
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16-Mar-10
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PROCHECK
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Headers
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References
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O94768
(ST17B_HUMAN) -
Serine/threonine-protein kinase 17B from Homo sapiens
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Seq:
Struc:
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372 a.a.
278 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 7 residue positions (black
crosses)
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Enzyme class:
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E.C.2.7.11.1
- non-specific serine/threonine protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
