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PDBsum entry 3llt
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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Crystal structure of pf14_0431, kinase domain.
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Structure:
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Serine/threonine kinase-1, pflammer. Chain: a. Fragment: unp residues 534-875. Engineered: yes
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Source:
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Plasmodium falciparum 3d7. Organism_taxid: 36329. Gene: lammer, pf14_0431. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.50Å
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R-factor:
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0.225
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R-free:
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0.267
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Authors:
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A.K.Wernimont,W.Tempel,Y.H.Lin,P.Loppnau,F.Mackenzie,H.Sullivan, J.Weadge,I.Kozieradzki,D.Cossar,G.Sinesterra,M.Vedadi, C.H.Arrowsmith,A.M.Edwards,C.Bountra,J.Weigelt,A.Bochkarev,R.Hui, W.Qiu,A.Hutchinson,Structural Genomics Consortium (Sgc)
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Key ref:
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A.K.Wernimont
et al.
Crystal structure of pf14_0431, Kinase domain..
To be published,
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Date:
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29-Jan-10
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Release date:
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04-Aug-10
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PROCHECK
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Headers
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References
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Q8IL19
(Q8IL19_PLAF7) -
Protein serine/threonine kinase-1 from Plasmodium falciparum (isolate 3D7)
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Seq:
Struc:
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881 a.a.
341 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.11.1
- non-specific serine/threonine protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
Bound ligand (Het Group name = )
matches with 81.25% similarity
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
Bound ligand (Het Group name = )
matches with 81.25% similarity
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
