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PDBsum entry 3ljj
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protein ligands metals links
Hydrolase/hydrolase inhibitor PDB id
3ljj

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
223 a.a. *
Ligands
10U
SO4 ×2
Metals
_CA
Waters ×195
* Residue conservation analysis
PDB id:
3ljj
Name: Hydrolase/hydrolase inhibitor
Title: Bovine trypsin in complex with ub-thr 10
Structure: Cationic trypsin. Chain: a. Fragment: residues 24-246. Synonym: beta-trypsin, alpha-trypsin chain 1, alpha-trypsin chain 2. Engineered: yes
Source: Bos taurus. Bovine. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 562
Resolution:
1.55Å     R-factor:   0.259     R-free:   0.220
Authors: C.Wegscheid-Gerlach,A.Heine,G.Klebe
Key ref: T.Brandt et al. (2011). Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties. J Mol Biol, 405, 1170-1187. PubMed id: 21111747
Date:
26-Jan-10     Release date:   06-Oct-10    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00760  (TRY1_BOVIN) -  Serine protease 1 from Bos taurus
Seq:
Struc: 		246 a.a.
223 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.21.4  - trypsin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

 

 
J Mol Biol 405:1170-1187 (2011)
PubMed id: 21111747  
 
 
Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties.
T.Brandt, N.Holzmann, L.Muley, M.Khayat, C.Wegscheid-Gerlach, B.Baum, A.Heine, D.Hangauer, G.Klebe.
 
  ABSTRACT  
 
No abstract given.

 

 

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