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PDBsum entry 3liz
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Hydrolase/immune system
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PDB id
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3liz
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Contents |
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329 a.a.
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211 a.a.
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213 a.a.
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* Residue conservation analysis
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PDB id:
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| Name: |
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Hydrolase/immune system
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Title:
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Crystal structure of bla g 2 complexed with fab 4c3
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Structure:
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Aspartic protease bla g 2. Chain: a. Synonym: allergen bla g ii. Engineered: yes. Mutation: yes. 4c3 monoclonal antibody light chain. Chain: l. 4c3 monoclonal antibody heavy chain. Chain: h
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Source:
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Blattella germanica. German cockroach. Organism_taxid: 6973. Expressed in: pichia pastoris. Expression_system_taxid: 4922. Mus musculus. Mouse. Organism_taxid: 10090. Other_details: hybridomas.
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Resolution:
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1.80Å
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R-factor:
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0.178
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R-free:
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0.202
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Authors:
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M.Li,A.Gustchina,J.Glesner,S.Wunschmann,A.Pomes,A.Wlodawer
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Key ref:
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J.Glesner
et al.
(2011).
Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
Plos One,
6,
e22223.
PubMed id:
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Date:
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25-Jan-10
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Release date:
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15-Dec-10
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PROCHECK
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Headers
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References
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P54958
(ASP2_BLAGE) -
Aspartic protease Bla g 2 from Blattella germanica
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Seq:
Struc:
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352 a.a.
329 a.a.*
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Plos One
6:e22223
(2011)
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PubMed id:
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Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
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J.Glesner,
S.Wünschmann,
M.Li,
A.Gustchina,
A.Wlodawer,
M.Himly,
M.D.Chapman,
A.Pomés.
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ABSTRACT
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Links
