| UniProt functional annotation for Q97ZE7 | |||
| UniProt code: Q97ZE7. |
| Organism: | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus). | |
| Taxonomy: | Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Saccharolobus. | |
| Function: | Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. {ECO:0000255|HAMAP-Rule:MF_00306}. | |
| Subunit: | Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19. {ECO:0000255|HAMAP-Rule:MF_00306}. | |
| Subcellular location: | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00306}. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00306}. | |
| Domain: | Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC. {ECO:0000255|HAMAP-Rule:MF_00306}. | |
| Similarity: | Belongs to the GTP-binding SRP family. SRP54 subfamily. {ECO:0000255|HAMAP-Rule:MF_00306}. | |
Annotations taken from UniProtKB at the EBI.