PDBsum entry 3kb5

Membrane protein

PDB id

3kb5

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Contents

			Protein chain

					193 a.a. *

			Waters ×160

* Residue conservation analysis

PDB id:

3kb5

Links

Name:

Membrane protein

Title:

Pry-spry domain of human trim72

Structure:

Tripartite motif-containing protein 72. Chain: a. Fragment: pry-spry domain, unp residues 278-470. Synonym: mitsugumin-53, mg53. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pry-spry. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.50Å

R-factor:

0.219

R-free:

0.237

Authors:

E.Y.Park,O.-B.Kwon,B.-C.Jeong,H.K.Song

Key ref:

E.Y.Park et al. (2010). Crystal structure of PRY-SPRY domain of human TRIM72. Proteins, 78, 790-795. PubMed id: 19967786

Date:

20-Oct-09

Release date:

22-Dec-09

PROCHECK

	Headers

	References

Protein chain

Q6ZMU5 (TRI72_HUMAN) - Tripartite motif-containing protein 72 from Homo sapiens

Seq: Struc:					477 a.a. 193 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.2.3.2.27 - RING-type E3 ubiquitin transferase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N₆- ubiquitinyl-[acceptor protein]-L-lysine

	Proteins 78:790-795 (2010)
PubMed id: 19967786

Crystal structure of PRY-SPRY domain of human TRIM72.
E.Y.Park, O.B.Kwon, B.C.Jeong, J.S.Yi, C.S.Lee, Y.G.Ko, H.K.Song.

ABSTRACT

No abstract given.

Literature references that cite this PDB file's key reference

PubMed id

Reference

20561531

P.Filippakopoulos, A.Low, T.D.Sharpe, J.Uppenberg, S.Yao, Z.Kuang, P.Savitsky, R.S.Lewis, S.E.Nicholson, R.S.Norton, and A.N.Bullock (2010).
Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.

J Mol Biol, 401, 389-402.

PDB codes:

2jk9 2v24 3emw 3f2o

The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.