UniProt functional annotation for P95803

UniProt code: P95803.

Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159).
Taxonomy: Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus.
 
Function: Cell wall formation. {ECO:0000255|HAMAP-Rule:MF_00047}.
 
Catalytic activity: ATP + 2 D-alanine = ADP + phosphate + D- alanyl-D-alanine. {ECO:0000255|HAMAP-Rule:MF_00047}.
Cofactor: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Note=Binds 2 magnesium or manganese ions per subunit. {ECO:0000250};
Pathway: Cell wall biogenesis; peptidoglycan biosynthesis. {ECO:0000255|HAMAP-Rule:MF_00047}.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00047}.
Similarity: Belongs to the D-alanine--D-alanine ligase family. {ECO:0000255|HAMAP-Rule:MF_00047}.

Annotations taken from UniProtKB at the EBI.