PDBsum entry 3k2j

Transcription

PDB id: 3k2j

Contents

Protein chains

121 a.a. *

Ligands

SO4 ×2

Metals

_CL ×2

Waters ×54

* Residue conservation analysis

PDB id:

3k2j

Name:

Transcription

Title:

Crystal structure of the 3rd bromodomain of human poly-bromodomain containing protein 1 (pb1)

Structure:

Protein polybromo-1. Chain: a, b. Fragment: bromo 3 domain, unp residues 388-494. Synonym: pb1, hpb1, polybromo-1d, brg1-associated factor 180, baf180. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pb1. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.20Å R-factor: 0.227 R-free: 0.270

Authors:

P.Filippakopoulos,S.Picaud,T.Keates,A.Chaikuad,A.C.W.Pike,T.Krojer, R.Sethi,F.Von Delft,C.H.Arrowsmith,A.Edwards,J.Weigelt,C.Bountra, S.Knapp,Structural Genomics Consortium (Sgc)

Key ref:

P.Filippakopoulos et al. Crystal structure of the 3rd bromodomain of human poly-Bromodomain containing protein 1 (pb1). To be published, .

Date:

30-Sep-09 Release date: 13-Oct-09

Protein chains

Q86U86  (PB1_HUMAN) -  Protein polybromo-1 from Homo sapiens

Seq: 1689 a.a.

Struc: 121 a.a.*

* PDB and UniProt seqs differ at 14 residue positions (black crosses)