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PDBsum entry 3k1q
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PDB id:
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VIRUS
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Title:
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Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics
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Structure:
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VP1, the protein that forms the mRNA-capping machine, VP3A, the building block protein of inner shell, VP3B, the building block protein of inner shell, VP6A and VP6B, the clamping proteins, VP7: protector protein (outer shell), VP5: membrane-penetration protein (outer shell
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Authors:
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Cheng, L.P., Zhu, J., Hiu, W.H., Zhang, X.K., Honig, B., Fang, Q., Zhou, Z.H.
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Key ref:
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.
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Note. PDBsum analyses are not available for this structure because
of its large size. To
get more detailed information on it, please go to its
PDBe page.
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Enzyme class 1:
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E.C.2.1.1.56
- mRNA (guanine-N(7))-methyltransferase.
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Reaction:
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a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L- methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine
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5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA
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+
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S-adenosyl-L- methionine
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=
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5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA
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+
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S-adenosyl-L-homocysteine
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Enzyme class 2:
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E.C.2.7.7.50
- mRNA guanylyltransferase.
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Reaction:
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a 5'-end diphospho-ribonucleoside in mRNA + GTP + H+ = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate
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5'-end diphospho-ribonucleoside in mRNA
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GTP
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+
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H(+)
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=
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5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA
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+
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diphosphate
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
