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PDBsum entry 3jzh
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Gene regulation
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PDB id
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3jzh
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Gene regulation
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Title:
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Eed-h3k79me3
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Structure:
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Polycomb protein eed. Chain: a. Synonym: heed, wd protein associating with integrin cytoplasmic tails 1, wait-1. Engineered: yes. Histone peptide. Chain: b. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: eed. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
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Resolution:
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2.05Å
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R-factor:
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0.163
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R-free:
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0.218
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Authors:
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C.Xu,C.B.Bian,C.Bountra,J.Weigelt,C.H.Arrowsmith,A.M.Edwards, A.Bochkarev,J.Min,Structural Genomics Consortium (Sgc)
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Key ref:
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C.Xu
et al.
(2010).
Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc Natl Acad Sci U S A,
107,
19266-19271.
PubMed id:
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Date:
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23-Sep-09
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Release date:
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15-Dec-09
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PROCHECK
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Headers
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References
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O75530
(EED_HUMAN) -
Polycomb protein EED from Homo sapiens
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Seq:
Struc:
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441 a.a.
359 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Proc Natl Acad Sci U S A
107:19266-19271
(2010)
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PubMed id:
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Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
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C.Xu,
C.Bian,
W.Yang,
M.Galka,
H.Ouyang,
C.Chen,
W.Qiu,
H.Liu,
A.E.Jones,
F.MacKenzie,
P.Pan,
S.S.Li,
H.Wang,
J.Min.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.A.Musselman,
M.E.Lalonde,
J.Côté,
and
T.G.Kutateladze
(2012).
Perceiving the epigenetic landscape through histone readers.
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Nat Struct Mol Biol,
19,
1218-1227.
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C.A.Musselman,
N.Avvakumov,
R.Watanabe,
C.G.Abraham,
M.E.Lalonde,
Z.Hong,
C.Allen,
S.Roy,
J.K.Nuñez,
J.Nickoloff,
C.A.Kulesza,
A.Yasui,
J.Côté,
and
T.G.Kutateladze
(2012).
Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
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Nat Struct Mol Biol,
19,
1266-1272.
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PDB code:
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C.Xu,
and
J.Min
(2011).
Structure and function of WD40 domain proteins.
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Protein Cell,
2,
202-214.
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PDB codes:
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F.W.Schmitges,
A.B.Prusty,
M.Faty,
A.Stützer,
G.M.Lingaraju,
J.Aiwazian,
R.Sack,
D.Hess,
L.Li,
S.Zhou,
R.D.Bunker,
U.Wirth,
T.Bouwmeester,
A.Bauer,
N.Ly-Hartig,
K.Zhao,
H.Chan,
J.Gu,
H.Gut,
W.Fischle,
J.Müller,
and
N.H.Thomä
(2011).
Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks.
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Mol Cell,
42,
330-341.
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PDB codes:
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H.Cedar,
and
Y.Bergman
(2011).
Epigenetics of haematopoietic cell development.
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Nat Rev Immunol,
11,
478-488.
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M.Yun,
J.Wu,
J.L.Workman,
and
B.Li
(2011).
Readers of histone modifications.
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Cell Res,
21,
564-578.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
code is
shown on the right.
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Links
