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PDBsum entry 3jyf
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Hydrolase
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Title:
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The crystal structure of a 2,3-cyclic nucleotide 2- phosphodiesterase/3-nucleotidase bifunctional periplasmic precursor protein from klebsiella pneumoniae subsp. Pneumoniae mgh 78578
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Structure:
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2',3'-cyclic nucleotide 2'-phosphodiesterase/3'- nucleotidase bifunctional periplasmic protein. Chain: a, b. Fragment: sequence database residues 16-354. Engineered: yes
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Source:
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Klebsiella pneumoniae subsp. Pneumoniae. Organism_taxid: 272620. Strain: mgh 78578. Atcc: 700721. Gene: cpdb, kpn78578_45340, kpn_04607. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.43Å
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R-factor:
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0.182
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R-free:
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0.231
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Authors:
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Y.Fan,L.Volkart,G.Cobb,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)
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Key ref:
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Y.Fan
et al.
The crystal structure of a 2,3-Cyclic nucleotide 2-Phosphodiesterase/3-Nucleotidase bifunctional periplasmic precursor protein from klebsiella pneumoniae subsp. Pneumoniae mgh 78578.
To be published,
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Date:
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21-Sep-09
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Release date:
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29-Sep-09
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PROCHECK
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Headers
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References
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A6THC4
(A6THC4_KLEP7) -
2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
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Seq:
Struc:
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647 a.a.
336 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class 2:
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E.C.3.1.3.6
- 3'-nucleotidase.
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Reaction:
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a ribonucleoside 3'-phosphate + H2O = a ribonucleoside + phosphate
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ribonucleoside 3'-phosphate
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+
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H2O
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=
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ribonucleoside
Bound ligand (Het Group name = )
matches with 50.00% similarity
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+
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phosphate
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Enzyme class 3:
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E.C.3.1.4.16
- 2',3'-cyclic-nucleotide 2'-phosphodiesterase.
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Reaction:
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a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 3'-phosphate + H+
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nucleoside 2',3'-cyclic phosphate
Bound ligand (Het Group name = )
matches with 41.18% similarity
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+
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H2O
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=
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nucleoside 3'-phosphate
Bound ligand (Het Group name = )
matches with 42.86% similarity
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+
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H(+)
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
