PDBsum entry 3j80 Go to PDB code:  Tunnel analysis for: 3j80 calculated with MOLE 2.0 PDB id 3j80 Tunnels calculated on whole structure Tunnels calculated excluding ligands View options MOLEonline 2.0 manipulation and visualization with HETATM: without HETATM:   30 tunnels, coloured by tunnel radius 38 tunnels, coloured by tunnel radius 38 tunnels, coloured as in list below Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown. Tunnels Free R Length HPathy HPhob Polar Rel Mut Residue..type Ligands Radius 1 1.48 1.48 66.0 -1.20 -0.60 14.7 81 5 0 1 1 1 0 0  U 52 2 G 53 2 C 54 2 U 56 2 G 57 2 A 92 2 A 93 2 U 94 2 G 95 2 G 96 2 U 117 2 U 157 2 U 158 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 G 403 2 C 413 2 C 414 2 A 420 2 G 422 2 MG 1802 2 2 1.29 1.29 66.6 -0.56 -0.77 4.9 65 1 0 0 0 0 1 0  A 41 2 G 42 2 A 43 2 G 95 2 G 96 2 C 97 2 U 98 2 U 118 2 C 297 2 A 298 2 A 299 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 A 396 2 G 397 2 C 426 2 A 427 2 G 428 2 G 429 2 C 430 2 G 431 2 G 433 2 A 437 2 MG 1820 2 MG 1832 2 MG 1853 2 3 1.48 1.48 67.1 -1.00 -0.62 11.8 77 4 0 1 1 1 1 0  U 52 2 G 53 2 C 54 2 U 56 2 G 57 2 A 92 2 A 93 2 U 94 2 G 95 2 G 96 2 U 118 2 U 157 2 U 158 2 C 297 2 A 298 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 G 403 2 C 413 2 C 414 2 A 420 2 G 422 2 MG 1802 2 4 1.37 1.37 69.1 -0.92 -0.59 12.3 78 4 0 0 1 1 0 0  U 94 2 G 96 2 U 117 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 C 404 2 U 405 2 A 406 2 C 407 2 A 411 2 G 418 2 A 419 2 A 420 2 G 421 2 G 422 2 C 423 2 G 425 2 5 1.36 1.37 70.3 -0.71 -0.62 8.8 74 3 0 0 1 1 1 0  U 94 2 G 96 2 U 118 2 C 297 2 A 298 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 C 404 2 U 405 2 A 406 2 C 407 2 A 411 2 G 418 2 A 419 2 A 420 2 G 421 2 G 422 2 C 423 2 G 425 2 6 1.50 1.50 71.4 -0.58 -0.65 7.8 80 3 0 0 1 1 0 0  A 41 2 G 42 2 A 43 2 U 94 2 G 95 2 G 96 2 C 97 2 U 98 2 U 117 2 A 299 2 A 300 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 G 385 2 A 396 2 G 397 2 A 399 2 C 426 2 A 427 2 G 428 2 G 429 2 C 430 2 G 431 2 G 433 2 A 437 2 MG 1820 2 MG 1832 2 MG 1853 2 7 1.26 1.26 72.0 -0.69 -0.77 5.6 78 2 0 2 0 0 2 0  A 41 2 G 42 2 G 95 2 G 96 2 C 97 2 U 98 2 U 118 2 C 297 2 A 298 2 A 299 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 A 396 2 G 397 2 C 426 2 A 427 2 A 437 2 A 440 2 C 441 2 C 442 2 G 458 2 A 459 2 G 460 2 G 461 2 U 462 2 MG 1836 2 MG 1853 2 8 1.27 1.27 75.4 -1.26 -0.54 15.8 77 8 3 2 2 1 1 0  U 111 2 A 112 2 U 113 2 U 118 2 U 244 2 G 245 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 C 736 2 A 737 2 9 1.40 1.40 76.9 -0.72 -0.66 8.3 82 4 0 2 1 1 1 0  A 41 2 G 42 2 U 94 2 G 95 2 G 96 2 C 97 2 U 98 2 U 117 2 A 299 2 A 300 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 G 385 2 A 396 2 G 397 2 A 399 2 C 426 2 A 427 2 A 437 2 A 440 2 C 441 2 C 442 2 G 458 2 A 459 2 G 460 2 G 461 2 U 462 2 MG 1832 2 MG 1836 2 MG 1853 2 10 1.30 1.30 77.2 -1.30 -0.56 16.0 77 9 3 2 2 1 1 0  U 111 2 A 112 2 U 113 2 U 117 2 U 244 2 G 245 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 C 736 2 A 737 2 11 1.48 1.48 78.0 -1.20 -0.60 15.3 77 7 0 0 1 1 0 0  U 56 2 G 57 2 U 58 2 A 84 2 A 85 2 A 86 2 A 92 2 A 93 2 U 94 2 G 95 2 G 96 2 U 117 2 U 158 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 G 403 2 G 456 2 MG 1802 2 12 1.48 1.48 79.2 -1.10 -0.63 13.4 74 6 0 0 1 1 1 0  U 56 2 G 57 2 U 58 2 A 84 2 A 85 2 A 86 2 A 92 2 A 93 2 U 94 2 G 95 2 G 96 2 U 118 2 U 158 2 C 297 2 A 298 2 A 299 2 A 300 2 A 384 2 G 385 2 A 386 2 A 396 2 G 397 2 A 399 2 C 401 2 G 402 2 G 403 2 G 456 2 MG 1802 2 13 1.28 1.28 78.4 -0.56 -0.75 4.5 62 1 0 0 0 0 2 0  G 34 2 U 35 2 C 36 2 U 37 2 C 38 2 A 39 2 A 40 2 A 41 2 G 42 2 G 95 2 G 96 2 C 97 2 U 98 2 U 118 2 C 297 2 A 298 2 A 299 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 A 396 2 G 397 2 A 427 2 A 437 2 G 460 2 G 461 2 U 462 2 A 463 2 G 464 2 U 465 2 G 466 2 U 516 2 A 528 2 MG 1836 2 MG 1853 2 14 1.27 1.27 79.9 -0.79 -0.50 10.7 71 5 0 2 3 1 2 0  U 111 2 A 112 2 U 113 2 C 114 2 U 118 2 U 240 2 U 241 2 G 242 2 A 243 2 U 244 2 A 246 2 U 247 2 A 252 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 15 1.28 1.48 81.3 -0.68 -0.61 9.7 87 6 0 0 5 1 0 0  A 103 2 A 104 2 A 105 2 U 106 2 C 107 2 U 117 2 A 299 2 A 300 2 U 301 2 U 302 2 U 303 2 C 304 2 U 305 2 U 317 2 C 353 2 G 354 2 G 355 2 G 383 2 A 384 2 A 396 2 G 397 2 G 1661 2 C 1662 2 U 1663 2 U 1736 2 16 1.34 1.34 81.8 -0.89 -0.52 11.7 72 6 0 2 3 1 2 0  U 111 2 A 112 2 U 113 2 C 114 2 U 117 2 U 240 2 U 241 2 G 242 2 A 243 2 U 244 2 A 246 2 U 247 2 A 252 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 17 1.50 1.60 83.3 -0.57 -0.66 6.8 76 3 0 0 1 1 1 0  G 34 2 U 35 2 C 36 2 U 37 2 C 38 2 A 39 2 A 40 2 A 41 2 G 42 2 U 94 2 G 95 2 G 96 2 C 97 2 U 98 2 U 117 2 A 299 2 A 300 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 G 385 2 A 396 2 G 397 2 A 399 2 A 427 2 A 437 2 G 460 2 G 461 2 U 462 2 A 463 2 G 464 2 U 465 2 G 466 2 U 516 2 A 528 2 MG 1832 2 MG 1836 2 MG 1853 2 18 1.34 1.34 86.7 -0.60 -0.70 7.0 86 4 0 0 4 0 1 0  A 103 2 A 104 2 A 105 2 U 106 2 C 107 2 A 108 2 G 109 2 U 118 2 C 297 2 A 298 2 A 299 2 U 302 2 U 303 2 C 304 2 U 305 2 U 317 2 C 353 2 G 354 2 G 355 2 G 382 2 G 383 2 A 396 2 G 397 2 G 1661 2 C 1662 2 U 1663 2 U 1736 2 19 1.27 1.27 92.0 -1.39 -0.60 14.9 84 7 2 4 1 1 2 0  U 111 2 U 113 2 U 118 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 U 648 2 U 649 2 U 678 2 G 751 2 A 753 2 A 754 2 A 755 2 A 756 2 U 789 2 A 790 2 20 1.34 1.34 93.9 -1.39 -0.60 15.6 84 8 2 4 1 1 2 0  U 111 2 U 113 2 U 117 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 U 648 2 U 649 2 U 678 2 G 751 2 A 753 2 A 754 2 A 755 2 A 756 2 U 789 2 A 790 2 21 1.29 1.29 96.9 -0.91 -0.72 9.6 69 6 0 0 0 1 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 U 128 2 U 202 2 G 203 2 U 204 2 A 205 2 U 206 2 U 207 2 U 208 2 A 209 2 C 249 2 A 250 2 A 253 2 U 254 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 22 1.33 1.33 98.8 -0.93 -0.73 10.1 70 7 0 0 0 1 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 U 128 2 U 202 2 G 203 2 U 204 2 A 205 2 U 206 2 U 207 2 U 208 2 A 209 2 C 249 2 A 250 2 A 253 2 U 254 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 23 1.39 1.52 100.0 -0.84 -0.61 10.5 86 7 0 1 3 1 0 0  A 104 2 A 105 2 U 106 2 C 107 2 U 117 2 A 299 2 A 300 2 U 301 2 U 302 2 U 303 2 C 304 2 U 305 2 C 307 2 U 310 2 A 311 2 U 312 2 A 351 2 A 352 2 G 383 2 A 384 2 A 396 2 G 397 2 A 969 2 A 970 2 G 971 2 A 972 2 U 1105 2 U 1119 2 C 1120 2 C 1127 2 U 1128 2 24 1.28 1.28 100.2 -0.89 -0.64 10.6 76 7 0 1 2 1 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 A 119 2 U 120 2 U 121 2 U 122 2 G 123 2 A 124 2 U 125 2 G 284 2 C 285 2 G 286 2 G 289 2 G 290 2 U 292 2 C 293 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 25 1.26 1.26 102.0 -0.96 -0.66 11.2 76 8 0 1 2 1 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 A 119 2 U 120 2 U 121 2 U 122 2 G 123 2 A 124 2 U 125 2 G 284 2 C 285 2 G 286 2 G 289 2 G 290 2 U 292 2 C 293 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 26 1.36 1.35 105.4 -0.83 -0.70 8.5 86 5 0 1 2 0 1 0  A 104 2 A 105 2 U 106 2 C 107 2 A 108 2 G 109 2 U 118 2 C 297 2 A 298 2 A 299 2 U 302 2 U 303 2 C 304 2 U 305 2 C 307 2 U 310 2 A 311 2 U 312 2 A 351 2 A 352 2 G 382 2 G 383 2 A 396 2 G 397 2 A 969 2 A 970 2 G 971 2 A 972 2 U 1105 2 U 1119 2 C 1120 2 C 1127 2 U 1128 2 27 1.27 1.27 110.1 -0.73 -0.59 9.2 87 8 1 2 3 1 1 0  U 111 2 A 112 2 U 113 2 U 118 2 G 245 2 U 296 2 C 297 2 A 298 2 A 299 2 C 350 2 G 382 2 A 396 2 G 397 2 A 629 2 G 630 2 U 744 2 U 745 2 A 746 2 C 797 2 A 798 2 U 807 2 G 808 2 28 1.26 1.26 109.8 -0.40 -0.50 7.5 74 5 0 2 4 3 2 0  C 38 2 A 39 2 A 40 2 A 41 2 G 42 2 G 95 2 G 96 2 C 97 2 U 98 2 U 118 2 C 297 2 A 298 2 A 299 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 A 396 2 G 397 2 A 427 2 A 437 2 G 460 2 G 461 2 U 462 2 A 463 2 U 523 2 G 772 2 A 774 2 G 775 2 C 783 2 U 784 2 MG 1832 2 MG 1836 2 MG 1853 2 29 1.26 1.26 112.1 -1.09 -0.62 12.5 83 7 1 4 2 1 2 0  U 1 2 A 108 2 G 109 2 U 118 2 C 297 2 A 298 2 A 299 2 G 362 2 G 363 2 A 365 2 A 366 2 U 367 2 A 368 2 G 370 2 G 371 2 G 372 2 U 373 2 C 381 2 G 382 2 A 396 2 G 397 2 A 754 2 A 755 2 U 759 2 A 760 2 U 791 2 A 792 2 U 793 2 U 794 2 30 1.28 1.28 111.7 -1.01 -0.76 7.6 72 5 0 2 0 1 2 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 C 171 2 A 172 2 U 173 2 U 206 2 A 250 2 U 259 2 U 260 2 U 261 2 C 262 2 G 290 2 U 291 2 U 292 2 C 293 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 A 1716 2 A 1717 2 31 1.28 1.28 114.0 -1.14 -0.62 13.2 83 8 1 4 2 1 2 0  U 1 2 A 108 2 G 109 2 U 117 2 A 298 2 A 299 2 G 362 2 G 363 2 A 365 2 A 366 2 U 367 2 A 368 2 G 370 2 G 371 2 G 372 2 U 373 2 C 381 2 G 382 2 A 396 2 G 397 2 A 754 2 A 755 2 U 759 2 A 760 2 U 791 2 A 792 2 U 793 2 U 794 2 32 1.26 1.26 111.9 -0.74 -0.59 9.5 87 9 1 2 3 1 1 0  U 111 2 A 112 2 U 113 2 U 117 2 G 245 2 U 296 2 C 297 2 A 298 2 A 299 2 C 350 2 G 382 2 A 396 2 G 397 2 A 629 2 G 630 2 U 744 2 U 745 2 A 746 2 C 797 2 A 798 2 U 807 2 G 808 2 33 1.26 1.26 113.5 -1.03 -0.76 8.2 73 6 0 2 0 1 2 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 C 171 2 A 172 2 U 173 2 U 206 2 A 250 2 U 259 2 U 260 2 U 261 2 C 262 2 G 290 2 U 291 2 U 292 2 C 293 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 A 1716 2 A 1717 2 34 1.34 1.34 114.9 -0.91 -0.59 11.0 73 7 0 1 2 3 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 U 207 2 U 208 2 A 209 2 U 210 2 U 211 2 A 212 2 G 213 2 U 248 2 C 249 2 A 250 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 U 829 2 U 835 2 G 836 2 MG 1850 2 35 1.50 1.52 114.7 -0.42 -0.42 9.4 77 8 0 2 5 4 1 0  C 38 2 A 39 2 A 40 2 A 41 2 G 42 2 U 94 2 G 95 2 G 96 2 C 97 2 U 98 2 U 117 2 A 299 2 A 300 2 U 378 2 U 379 2 C 381 2 G 382 2 G 383 2 A 384 2 G 385 2 A 396 2 G 397 2 A 399 2 A 427 2 A 437 2 G 460 2 G 461 2 U 462 2 A 463 2 U 523 2 G 772 2 A 774 2 G 775 2 C 783 2 U 784 2 MG 1832 2 MG 1836 2 MG 1853 2 36 1.28 1.28 116.7 -0.91 -0.58 11.3 73 8 0 1 2 3 1 0  U 111 2 A 112 2 U 113 2 C 114 2 U 116 2 U 117 2 U 118 2 U 207 2 U 208 2 A 209 2 U 210 2 U 211 2 A 212 2 G 213 2 U 248 2 C 249 2 A 250 2 A 294 2 U 295 2 U 296 2 C 297 2 A 298 2 A 299 2 G 382 2 A 396 2 G 397 2 U 829 2 U 835 2 G 836 2 MG 1850 2 37 1.24 1.44 125.5 -0.75 -0.52 9.9 80 8 0 1 4 2 0 0  A 104 2 A 105 2 U 106 2 C 107 2 U 117 2 A 299 2 A 300 2 U 301 2 U 302 2 U 303 2 C 304 2 U 305 2 C 307 2 U 310 2 A 311 2 U 312 2 A 351 2 A 352 2 G 383 2 A 384 2 A 396 2 G 397 2 U 1116 2 G 1129 2 A 1130 2 U 1648 2 A 1649 2 C 1650 2 C 1651 2 G 1652 2 U 1739 2 U 1740 2 U 1741 2 A 1742 2 G 1743 2 38 1.12 1.37 22.1 0.23 -0.04 10.0 87 2 1 3 6 0 0 0   Residue-type_colouring Positive Negative Neutral Aliphatic Aromatic Pro & Gly Cysteine H,K,R D,E S,T,N,Q A,V,L,I,M F,Y,W P,G C Acknowledgement Tunnels were calculated by MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.