UniProt functional annotation for P0ADZ0

UniProt code: P0ADZ0.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
 
Function: One of the early assembly proteins, it binds 23S rRNA; is essential for growth. One of the proteins that surround the polypeptide exit tunnel on the outside of the subunit. Acts as the docking site for trigger factor (PubMed:12226666) for Ffh binding to the ribosome (SRP54, PubMed:12756233 and PubMed:12702815) and to nascent polypeptide chains (PubMed:12756233).
 
Subunit: Part of the 50S ribosomal subunit. Contacts protein L29 and trigger factor. Might also contact SecE and probably does contact SecG and SecY when the SecYEG translocation complex is docked with the ribosome.
Mass spectrometry: Mass=11198.0; Method=MALDI; Range=1-100; Source=PubMed:10094780;
Similarity: Belongs to the ribosomal protein L23P family.

Annotations taken from UniProtKB at the EBI.