UniProt functional annotation for P0CX53

UniProt codes: P0CX53, P17079.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Function: This protein binds directly to 26S ribosomal RNA.
Subunit: Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).
Subcellular location: Cytoplasm.
Ptm: It appears that the main modified species for L12 contains 6 methyl groups, 2 on Pro-2, 3 on Lys-4 and 1 on Arg-67. Although not reproduced with a second method, methylation at Lys-11 cannot be ruled out.
Mass spectrometry: Mass=17764.712; Method=Electrospray; Range=2- 106; Note=Monoisotopic mass with either 6 methylation modifications or 1 acetylation and 3 methylation modifications; Source=PubMed:11983894;
Miscellaneous: Present with 68500 molecules/cell in log phase SD medium.
Miscellaneous: There are 2 genes for L12 in yeast.
Similarity: Belongs to the ribosomal protein L11P family.

Annotations taken from UniProtKB at the EBI.