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PDBsum entry 3izr

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Ribosome PDB id
3izr
Jmol
Contents
Protein chains
216 a.a.
255 a.a.
170 a.a.
190 a.a.
201 a.a.
140 a.a.
194 a.a.
144 a.a.
163 a.a.
304 a.a.
189 a.a.
164 a.a.
171 a.a.
122 a.a.
75 a.a.
130 a.a.
73 a.a.
23 a.a.
112 a.a.
120 a.a.
133 a.a.
94 a.a.
69 a.a.
51 a.a.
105 a.a.
25 a.a.
20 a.a.
14 a.a.
219 a.a.
182 a.a.
134 a.a.
167 a.a.
108 a.a.
99 a.a.
119 a.a.
104 a.a.
77 a.a.
41 a.a.
128 a.a.
58 a.a.
59 a.a.
124 a.a.
244 a.a.
262 a.a.
389 a.a.
372 a.a.
206 a.a.
92 a.a.
184 a.a.
HEADER    RIBOSOME                                06-DEC-10   3IZR
OBSLTE     05-FEB-14 3IZR      3J61
TITLE     LOCALIZATION OF THE LARGE SUBUNIT RIBOSOMAL PROTEINS INTO A 5.5 A
TITLE    2 CRYO-EM MAP OF TRITICUM AESTIVUM TRANSLATING 80S RIBOSOME
SPLIT      3IZR 3IZ6 3IZ7 3IZ9
CAVEAT     3IZR    THE ENTRY HAS SEVERAL CHIRALITY ERRORS (SEE REMARK 500)
CAVEAT     3IZR    THE ENTRY ALSO HAS SOME UNREALISTIC C-N BONDS
COMPND    MOL_ID: 1;
COMPND   2 MOLECULE: 60S RIBOSOMAL PROTEIN L1 (L1P);
COMPND   3 CHAIN: A;
COMPND   4 MOL_ID: 2;
COMPND   5 MOLECULE: 60S RIBOSOMAL PROTEIN L2 (L2P);
COMPND   6 CHAIN: B;
COMPND   7 MOL_ID: 3;
COMPND   8 MOLECULE: 60S RIBOSOMAL PROTEIN L11 (L5P);
COMPND   9 CHAIN: E;
COMPND  10 MOL_ID: 4;
COMPND  11 MOLECULE: 60S RIBOSOMAL PROTEIN L9 (L6P);
COMPND  12 CHAIN: F;
COMPND  13 MOL_ID: 5;
COMPND  14 MOLECULE: 60S RIBOSOMAL PROTEIN L7A (L7AE);
COMPND  15 CHAIN: H;
COMPND  16 MOL_ID: 6;
COMPND  17 MOLECULE: 60S RIBOSOMAL PROTEIN L23 (L14P);
COMPND  18 CHAIN: M;
COMPND  19 MOL_ID: 7;
COMPND  20 MOLECULE: 60S RIBOSOMAL PROTEIN L15 (L15E);
COMPND  21 CHAIN: P;
COMPND  22 MOL_ID: 8;
COMPND  23 MOLECULE: 60S RIBOSOMAL PROTEIN L27A (L15P);
COMPND  24 CHAIN: O;
COMPND  25 MOL_ID: 9;
COMPND  26 MOLECULE: 60S RIBOSOMAL PROTEIN L18 (L18E);
COMPND  27 CHAIN: R;
COMPND  28 MOL_ID: 10;
COMPND  29 MOLECULE: 60S RIBOSOMAL PROTEIN L5 (L18P);
COMPND  30 CHAIN: Q;
COMPND  31 MOL_ID: 11;
COMPND  32 MOLECULE: 60S RIBOSOMAL PROTEIN L19 (L19E);
COMPND  33 CHAIN: T;
COMPND  34 MOL_ID: 12;
COMPND  35 MOLECULE: 60S RIBOSOMAL PROTEIN L21 (L21E);
COMPND  36 CHAIN: U;
COMPND  37 MOL_ID: 13;
COMPND  38 MOLECULE: 60S RIBOSOMAL PROTEIN L17 (L22P);
COMPND  39 CHAIN: V;
COMPND  40 MOL_ID: 14;
COMPND  41 MOLECULE: 60S RIBOSOMAL PROTEIN L23A (L23P);
COMPND  42 CHAIN: X;
COMPND  43 MOL_ID: 15;
COMPND  44 MOLECULE: 60S RIBOSOMAL PROTEIN L24 (L24E);
COMPND  45 CHAIN: Z;
COMPND  46 MOL_ID: 16;
COMPND  47 MOLECULE: 60S RIBOSOMAL PROTEIN L26 (L24P);
COMPND  48 CHAIN: Y;
COMPND  49 MOL_ID: 17;
COMPND  50 MOLECULE: 60S RIBOSOMAL PROTEIN L28 (L28E);
COMPND  51 CHAIN: b;
COMPND  52 MOL_ID: 18;
COMPND  53 MOLECULE: 60S RIBOSOMAL PROTEIN L29 (L29E);
COMPND  54 CHAIN: d;
COMPND  55 MOL_ID: 19;
COMPND  56 MOLECULE: 60S RIBOSOMAL PROTEIN L30 (L30E);
COMPND  57 CHAIN: f;
COMPND  58 MOL_ID: 20;
COMPND  59 MOLECULE: 60S RIBOSOMAL PROTEIN L31 (L31E);
COMPND  60 CHAIN: g;
COMPND  61 MOL_ID: 21;
COMPND  62 MOLECULE: 60S RIBOSOMAL PROTEIN L32 (L32E);
COMPND  63 CHAIN: h;
COMPND  64 MOL_ID: 22;
COMPND  65 MOLECULE: 60S RIBOSOMAL PROTEIN L37 (L37E);
COMPND  66 CHAIN: l;
COMPND  67 MOL_ID: 23;
COMPND  68 MOLECULE: 60S RIBOSOMAL PROTEIN L38 (L38E);
COMPND  69 CHAIN: n;
COMPND  70 MOL_ID: 24;
COMPND  71 MOLECULE: 60S RIBOSOMAL PROTEIN L39 (L39E);
COMPND  72 CHAIN: o;
COMPND  73 MOL_ID: 25;
COMPND  74 MOLECULE: 60S RIBOSOMAL PROTEIN L42 (L44E);
COMPND  75 CHAIN: r;
COMPND  76 MOL_ID: 26;
COMPND  77 MOLECULE: 60S RIBOSOMAL PROTEIN L41 (L41E);
COMPND  78 CHAIN: q;
COMPND  79 MOL_ID: 27;
COMPND  80 MOLECULE: UNKNOWN 60S RIBOSOMAL PROTEIN XL;
COMPND  81 CHAIN: y, x;
COMPND  82 MOL_ID: 28;
COMPND  83 MOLECULE: UNKNOWN 60S RIBOSOMAL PROTEIN XL3;
COMPND  84 CHAIN: z;
COMPND  85 MOL_ID: 29;
COMPND  86 MOLECULE: 60S RIBOSOMAL PROTEIN L6 (L6E);
COMPND  87 CHAIN: G;
COMPND  88 MOL_ID: 30;
COMPND  89 MOLECULE: 60S RIBOSOMAL PROTEIN L13 (L13E);
COMPND  90 CHAIN: L;
COMPND  91 MOL_ID: 31;
COMPND  92 MOLECULE: 60S RIBOSOMAL PROTEIN L14 (L14E);
COMPND  93 CHAIN: N;
COMPND  94 MOL_ID: 32;
COMPND  95 MOLECULE: 60S RIBOSOMAL PROTEIN L18A (L18AE);
COMPND  96 CHAIN: S;
COMPND  97 MOL_ID: 33;
COMPND  98 MOLECULE: 60S RIBOSOMAL PROTEIN L22 (L22E);
COMPND  99 CHAIN: W;
COMPND 100 MOL_ID: 34;
COMPND 101 MOLECULE: 60S RIBOSOMAL PROTEIN L27 (L27E);
COMPND 102 CHAIN: a;
COMPND 103 MOL_ID: 35;
COMPND 104 MOLECULE: 60S RIBOSOMAL PROTEIN L34 (L34E);
COMPND 105 CHAIN: i;
COMPND 106 MOL_ID: 36;
COMPND 107 MOLECULE: 60S RIBOSOMAL PROTEIN L35A (L35AE);
COMPND 108 CHAIN: j;
COMPND 109 MOL_ID: 37;
COMPND 110 MOLECULE: 60S RIBOSOMAL PROTEIN L36 (L36E);
COMPND 111 CHAIN: k;
COMPND 112 MOL_ID: 38;
COMPND 113 MOLECULE: 60S RIBOSOMAL PROTEIN L40 (L40E);
COMPND 114 CHAIN: p;
COMPND 115 MOL_ID: 39;
COMPND 116 MOLECULE: 60S RIBOSOMAL PROTEIN L12 (L11P);
COMPND 117 CHAIN: J;
COMPND 118 MOL_ID: 40;
COMPND 119 MOLECULE: 60S ACIDIC RIBOSOMAL PROTEIN P11 - P1 (L12P);
COMPND 120 CHAIN: t, u;
COMPND 121 MOL_ID: 41;
COMPND 122 MOLECULE: 60S ACIDIC RIBOSOMAL PROTEIN P21 - P2 (L12P);
COMPND 123 CHAIN: v, w;
COMPND 124 MOL_ID: 42;
COMPND 125 MOLECULE: 60S RIBOSOMAL PROTEIN L35 (L29P);
COMPND 126 CHAIN: c;
COMPND 127 MOL_ID: 43;
COMPND 128 MOLECULE: 60S RIBOSOMAL PROTEIN L7 (L30P);
COMPND 129 CHAIN: e;
COMPND 130 MOL_ID: 44;
COMPND 131 MOLECULE: 60S ACIDIC RIBOSOMAL PROTEIN P0 (L10P);
COMPND 132 CHAIN: s;
COMPND 133 MOL_ID: 45;
COMPND 134 MOLECULE: 60S RIBOSOMAL PROTEIN L3 (L3P);
COMPND 135 CHAIN: C;
COMPND 136 MOL_ID: 46;
COMPND 137 MOLECULE: 60S RIBOSOMAL PROTEIN L4 (L4P);
COMPND 138 CHAIN: D;
COMPND 139 MOL_ID: 47;
COMPND 140 MOLECULE: 60S RIBOSOMAL PROTEIN L13A (L13P);
COMPND 141 CHAIN: K;
COMPND 142 MOL_ID: 48;
COMPND 143 MOLECULE: 60S RIBOSOMAL PROTEIN L43 (L37AE);
COMPND 144 CHAIN: m;
COMPND 145 MOL_ID: 49;
COMPND 146 MOLECULE: 60S RIBOSOMAL PROTEIN L10 (L10E);
COMPND 147 CHAIN: I
SOURCE    MOL_ID: 1;
SOURCE   2 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE   3 ORGANISM_COMMON: WHEAT;
SOURCE   4 ORGANISM_TAXID: 4565;
SOURCE   5 MOL_ID: 2;
SOURCE   6 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE   7 ORGANISM_COMMON: WHEAT;
SOURCE   8 ORGANISM_TAXID: 4565;
SOURCE   9 MOL_ID: 3;
SOURCE  10 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  11 ORGANISM_COMMON: WHEAT;
SOURCE  12 ORGANISM_TAXID: 4565;
SOURCE  13 MOL_ID: 4;
SOURCE  14 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  15 ORGANISM_COMMON: WHEAT;
SOURCE  16 ORGANISM_TAXID: 4565;
SOURCE  17 MOL_ID: 5;
SOURCE  18 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  19 ORGANISM_COMMON: WHEAT;
SOURCE  20 ORGANISM_TAXID: 4565;
SOURCE  21 MOL_ID: 6;
SOURCE  22 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  23 ORGANISM_COMMON: WHEAT;
SOURCE  24 ORGANISM_TAXID: 4565;
SOURCE  25 MOL_ID: 7;
SOURCE  26 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  27 ORGANISM_COMMON: WHEAT;
SOURCE  28 ORGANISM_TAXID: 4565;
SOURCE  29 MOL_ID: 8;
SOURCE  30 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  31 ORGANISM_COMMON: WHEAT;
SOURCE  32 ORGANISM_TAXID: 4565;
SOURCE  33 MOL_ID: 9;
SOURCE  34 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  35 ORGANISM_COMMON: WHEAT;
SOURCE  36 ORGANISM_TAXID: 4565;
SOURCE  37 MOL_ID: 10;
SOURCE  38 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  39 ORGANISM_COMMON: WHEAT;
SOURCE  40 ORGANISM_TAXID: 4565;
SOURCE  41 MOL_ID: 11;
SOURCE  42 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  43 ORGANISM_COMMON: WHEAT;
SOURCE  44 ORGANISM_TAXID: 4565;
SOURCE  45 MOL_ID: 12;
SOURCE  46 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  47 ORGANISM_COMMON: WHEAT;
SOURCE  48 ORGANISM_TAXID: 4565;
SOURCE  49 MOL_ID: 13;
SOURCE  50 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  51 ORGANISM_COMMON: WHEAT;
SOURCE  52 ORGANISM_TAXID: 4565;
SOURCE  53 MOL_ID: 14;
SOURCE  54 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  55 ORGANISM_COMMON: WHEAT;
SOURCE  56 ORGANISM_TAXID: 4565;
SOURCE  57 MOL_ID: 15;
SOURCE  58 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  59 ORGANISM_COMMON: WHEAT;
SOURCE  60 ORGANISM_TAXID: 4565;
SOURCE  61 MOL_ID: 16;
SOURCE  62 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  63 ORGANISM_COMMON: WHEAT;
SOURCE  64 ORGANISM_TAXID: 4565;
SOURCE  65 MOL_ID: 17;
SOURCE  66 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  67 ORGANISM_COMMON: WHEAT;
SOURCE  68 ORGANISM_TAXID: 4565;
SOURCE  69 MOL_ID: 18;
SOURCE  70 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  71 ORGANISM_COMMON: WHEAT;
SOURCE  72 ORGANISM_TAXID: 4565;
SOURCE  73 MOL_ID: 19;
SOURCE  74 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  75 ORGANISM_COMMON: WHEAT;
SOURCE  76 ORGANISM_TAXID: 4565;
SOURCE  77 MOL_ID: 20;
SOURCE  78 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  79 ORGANISM_COMMON: WHEAT;
SOURCE  80 ORGANISM_TAXID: 4565;
SOURCE  81 MOL_ID: 21;
SOURCE  82 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  83 ORGANISM_COMMON: WHEAT;
SOURCE  84 ORGANISM_TAXID: 4565;
SOURCE  85 MOL_ID: 22;
SOURCE  86 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  87 ORGANISM_COMMON: WHEAT;
SOURCE  88 ORGANISM_TAXID: 4565;
SOURCE  89 MOL_ID: 23;
SOURCE  90 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  91 ORGANISM_COMMON: WHEAT;
SOURCE  92 ORGANISM_TAXID: 4565;
SOURCE  93 MOL_ID: 24;
SOURCE  94 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  95 ORGANISM_COMMON: WHEAT;
SOURCE  96 ORGANISM_TAXID: 4565;
SOURCE  97 MOL_ID: 25;
SOURCE  98 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE  99 ORGANISM_COMMON: WHEAT;
SOURCE 100 ORGANISM_TAXID: 4565;
SOURCE 101 MOL_ID: 26;
SOURCE 102 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 103 ORGANISM_COMMON: WHEAT;
SOURCE 104 ORGANISM_TAXID: 4565;
SOURCE 105 MOL_ID: 27;
SOURCE 106 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 107 ORGANISM_COMMON: WHEAT;
SOURCE 108 ORGANISM_TAXID: 4565;
SOURCE 109 MOL_ID: 28;
SOURCE 110 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 111 ORGANISM_COMMON: WHEAT;
SOURCE 112 ORGANISM_TAXID: 4565;
SOURCE 113 MOL_ID: 29;
SOURCE 114 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 115 ORGANISM_COMMON: WHEAT;
SOURCE 116 ORGANISM_TAXID: 4565;
SOURCE 117 MOL_ID: 30;
SOURCE 118 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 119 ORGANISM_COMMON: WHEAT;
SOURCE 120 ORGANISM_TAXID: 4565;
SOURCE 121 MOL_ID: 31;
SOURCE 122 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 123 ORGANISM_COMMON: WHEAT;
SOURCE 124 ORGANISM_TAXID: 4565;
SOURCE 125 MOL_ID: 32;
SOURCE 126 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 127 ORGANISM_COMMON: WHEAT;
SOURCE 128 ORGANISM_TAXID: 4565;
SOURCE 129 MOL_ID: 33;
SOURCE 130 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 131 ORGANISM_COMMON: WHEAT;
SOURCE 132 ORGANISM_TAXID: 4565;
SOURCE 133 MOL_ID: 34;
SOURCE 134 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 135 ORGANISM_COMMON: WHEAT;
SOURCE 136 ORGANISM_TAXID: 4565;
SOURCE 137 MOL_ID: 35;
SOURCE 138 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 139 ORGANISM_COMMON: WHEAT;
SOURCE 140 ORGANISM_TAXID: 4565;
SOURCE 141 MOL_ID: 36;
SOURCE 142 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 143 ORGANISM_COMMON: WHEAT;
SOURCE 144 ORGANISM_TAXID: 4565;
SOURCE 145 MOL_ID: 37;
SOURCE 146 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 147 ORGANISM_COMMON: WHEAT;
SOURCE 148 ORGANISM_TAXID: 4565;
SOURCE 149 MOL_ID: 38;
SOURCE 150 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 151 ORGANISM_COMMON: WHEAT;
SOURCE 152 ORGANISM_TAXID: 4565;
SOURCE 153 MOL_ID: 39;
SOURCE 154 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 155 ORGANISM_COMMON: WHEAT;
SOURCE 156 ORGANISM_TAXID: 4565;
SOURCE 157 MOL_ID: 40;
SOURCE 158 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 159 ORGANISM_COMMON: WHEAT;
SOURCE 160 ORGANISM_TAXID: 4565;
SOURCE 161 MOL_ID: 41;
SOURCE 162 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 163 ORGANISM_COMMON: WHEAT;
SOURCE 164 ORGANISM_TAXID: 4565;
SOURCE 165 MOL_ID: 42;
SOURCE 166 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 167 ORGANISM_COMMON: WHEAT;
SOURCE 168 ORGANISM_TAXID: 4565;
SOURCE 169 MOL_ID: 43;
SOURCE 170 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 171 ORGANISM_COMMON: WHEAT;
SOURCE 172 ORGANISM_TAXID: 4565;
SOURCE 173 MOL_ID: 44;
SOURCE 174 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 175 ORGANISM_COMMON: WHEAT;
SOURCE 176 ORGANISM_TAXID: 4565;
SOURCE 177 MOL_ID: 45;
SOURCE 178 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 179 ORGANISM_COMMON: WHEAT;
SOURCE 180 ORGANISM_TAXID: 4565;
SOURCE 181 MOL_ID: 46;
SOURCE 182 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 183 ORGANISM_COMMON: WHEAT;
SOURCE 184 ORGANISM_TAXID: 4565;
SOURCE 185 MOL_ID: 47;
SOURCE 186 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 187 ORGANISM_COMMON: WHEAT;
SOURCE 188 ORGANISM_TAXID: 4565;
SOURCE 189 MOL_ID: 48;
SOURCE 190 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 191 ORGANISM_COMMON: WHEAT;
SOURCE 192 ORGANISM_TAXID: 4565;
SOURCE 193 MOL_ID: 49;
SOURCE 194 ORGANISM_SCIENTIFIC: TRITICUM AESTIVUM;
SOURCE 195 ORGANISM_COMMON: WHEAT;
SOURCE 196 ORGANISM_TAXID: 4565
KEYWDS    EUKARYOTIC RIBOSOME,HOMOLOGY MODELING,DE NOVO MODELING,RIBOSOMAL
KEYWDS   2 PROTEINS,NOVEL RIBOSOMAL PROTEINS, RIBOSOME
EXPDTA    ELECTRON MICROSCOPY
AUTHOR    J.-P.ARMACHE,A.JARASCH,A.M.ANGER,E.VILLA,T.BECKER,S.BHUSHAN,
AUTHOR   2 F.JOSSINET,M.HABECK,G.DINDAR,S.FRANCKENBERG,V.MARQUEZ,MIELKE. T.,
AUTHOR   3 M.THOMM,O.BERNINGHAUSEN,B.BEATRIX,J.SOEDING,E.WESTHOF,D.N.WILSON,
AUTHOR   4 R.BECKMANN
REVDAT   4   05-FEB-14 3IZR    1       OBSLTE
REVDAT   3   27-JUL-11 3IZR    1       SEQADV VERSN
REVDAT   2   20-APR-11 3IZR    1       CRYST1
REVDAT   1   15-DEC-10 3IZR    0
SPRSDE     15-DEC-10 3IZR      3IZ5
JRNL        AUTH   J.P.ARMACHE,A.JARASCH,A.M.ANGER,E.VILLA,T.BECKER,S.BHUSHAN,
JRNL        AUTH 2 F.JOSSINET,M.HABECK,G.DINDAR,S.FRANCKENBERG,V.MARQUEZ,
JRNL        AUTH 3 T.MIELKE,M.THOMM,O.BERNINGHAUSEN,B.BEATRIX,J.SODING,
JRNL        AUTH 4 E.WESTHOF,D.N.WILSON,R.BECKMANN
JRNL        TITL   LOCALIZATION OF EUKARYOTE-SPECIFIC RIBOSOMAL PROTEINS IN A
JRNL        TITL 2 5.5-A CRYO-EM MAP OF THE 80S EUKARYOTIC RIBOSOME.
JRNL        REF    PROC.NATL.ACAD.SCI.USA        V. 107 19754 2010
JRNL        REFN                   ISSN 0027-8424
JRNL        PMID   20974910
JRNL        DOI    10.1073/PNAS.1010005107
REMARK   1
REMARK   1 REFERENCE 1
REMARK   1  AUTH   J.P.ARMACHE,A.JARASCH,A.M.ANGER,E.VILLA,T.BECKER,S.BHUSHAN,
REMARK   1  AUTH 2 F.JOSSINET,M.HABECK,G.DINDAR,S.FRANCKENBERG,V.MARQUEZ,
REMARK   1  AUTH 3 T.MIELKE,M.THOMM,O.BERNINGHAUSEN,B.BEATRIX,J.SODING,
REMARK   1  AUTH 4 E.WESTHOF,D.N.WILSON,R.BECKMANN
REMARK   1  TITL   CRYO-EM STRUCTURE AND RRNA MODEL OF A TRANSLATING EUKARYOTIC
REMARK   1  TITL 2 80S RIBOSOME AT 5.5-A RESOLUTION.
REMARK   1  REF    PROC.NATL.ACAD.SCI.USA        V. 107 19748 2010
REMARK   1  REFN                   ISSN 0027-8424
REMARK   1  PMID   20980660
REMARK   1  DOI    10.1073/PNAS.1009999107
REMARK   2
REMARK   2 RESOLUTION.    5.50 ANGSTROMS.
REMARK   3
REMARK   3 REFINEMENT.
REMARK   3   SOFTWARE PACKAGES      : NULL
REMARK   3   RECONSTRUCTION SCHEMA  : SINGLE PARTICLE
REMARK   3
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK   3   PDB ENTRY                    : NULL
REMARK   3   REFINEMENT SPACE             : NULL
REMARK   3   REFINEMENT PROTOCOL          : NULL
REMARK   3   REFINEMENT TARGET            : NULL
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL
REMARK   3
REMARK   3 FITTING PROCEDURE : NULL
REMARK   3
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : 1.238
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : 1.238
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 5.500
REMARK   3   NUMBER OF PARTICLES               : NULL
REMARK   3   CTF CORRECTION METHOD             : NULL
REMARK   3
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK   3
REMARK   3 OTHER DETAILS: NULL
REMARK   4
REMARK   4 3IZR COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 08-DEC-10.
REMARK 100 THE RCSB ID CODE IS RCSB160069.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE
REMARK 245   SPECIMEN TYPE                  : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245   SAMPLE TYPE                    : PARTICLE
REMARK 245   PARTICLE TYPE                  : ASYMMETRIC
REMARK 245   NAME OF SAMPLE                 : PROGRAMMED TRITICUM AESTIVUM
REMARK 245                                    80S RIBOSOME
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245   SAMPLE SUPPORT DETAILS         : NULL
REMARK 245   SAMPLE VITRIFICATION DETAILS   : NULL
REMARK 245   SAMPLE BUFFER                  : NULL
REMARK 245   PH                             : 7.50
REMARK 245   SAMPLE DETAILS                 : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245   DATE OF EXPERIMENT                : NULL
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : NULL
REMARK 245   TEMPERATURE (KELVIN)              : NULL
REMARK 245   MICROSCOPE MODEL                  : NULL
REMARK 245   DETECTOR TYPE                     : NULL
REMARK 245   MINIMUM DEFOCUS (NM)              : NULL
REMARK 245   MAXIMUM DEFOCUS (NM)              : NULL
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : NULL
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : NULL
REMARK 245   NOMINAL CS                        : NULL
REMARK 245   IMAGING MODE                      : NULL
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : NULL
REMARK 245   ILLUMINATION MODE                 : NULL
REMARK 245   NOMINAL MAGNIFICATION             : NULL
REMARK 245   CALIBRATED MAGNIFICATION          : NULL
REMARK 245   SOURCE                            : NULL
REMARK 245   ACCELERATION VOLTAGE (KV)         : NULL
REMARK 245   IMAGING DETAILS                   : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247  OF THE STRUCTURE FACTORS.
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1
REMARK 290
REMARK 290      SYMOP   SYMMETRY
REMARK 290     NNNMMM   OPERATOR
REMARK 290       1555   X,Y,Z
REMARK 290
REMARK 290     WHERE NNN -> OPERATOR NUMBER
REMARK 290           MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 52-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, E, F, H, I, M, P, O,
REMARK 350                    AND CHAINS: R, Q, T, U, V, X, Z, Y, b,
REMARK 350                    AND CHAINS: d, f, g, h, l, n, o, r, q,
REMARK 350                    AND CHAINS: y, z, G, L, N, S, W, a, i,
REMARK 350                    AND CHAINS: j, k, p, x, J, t, u, v, w,
REMARK 350                    AND CHAINS: c, e, s, C, D, K, m
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465   M RES C SSSEQI
REMARK 465     LYS B   256
REMARK 465     ALA B   257
REMARK 465     ASP B   258
REMARK 465     LYS B   259
REMARK 465     ALA B   260
REMARK 465     THR B   261
REMARK 465     GLY E   171
REMARK 465     VAL E   172
REMARK 465     ILE E   173
REMARK 465     LEU E   174
REMARK 465     ASN E   175
REMARK 465     LYS E   176
REMARK 465     SER E   177
REMARK 465     HIS E   178
REMARK 465     ALA E   179
REMARK 465     SER E   180
REMARK 465     MET H     1
REMARK 465     ALA H     2
REMARK 465     PRO H     3
REMARK 465     LYS H     4
REMARK 465     ARG H     5
REMARK 465     GLY H     6
REMARK 465     GLY H     7
REMARK 465     ARG H     8
REMARK 465     ALA H     9
REMARK 465     PRO H    10
REMARK 465     VAL H    11
REMARK 465     PRO H    12
REMARK 465     ALA H    13
REMARK 465     LYS H    14
REMARK 465     LYS H    15
REMARK 465     LYS H    16
REMARK 465     THR H    17
REMARK 465     GLU H    18
REMARK 465     LYS H    19
REMARK 465     VAL H    20
REMARK 465     THR H    21
REMARK 465     ASN H    22
REMARK 465     PRO H    23
REMARK 465     LEU H    24
REMARK 465     PHE H    25
REMARK 465     GLU H    26
REMARK 465     LYS H    27
REMARK 465     ARG H    28
REMARK 465     PRO H    29
REMARK 465     LYS H    30
REMARK 465     GLN H    31
REMARK 465     PHE H    32
REMARK 465     GLY H    33
REMARK 465     ILE H    34
REMARK 465     GLY H    35
REMARK 465     GLY H    36
REMARK 465     ALA H    37
REMARK 465     LEU H    38
REMARK 465     PRO H    39
REMARK 465     PRO H    40
REMARK 465     LYS H    41
REMARK 465     LYS H    42
REMARK 465     ASP H    43
REMARK 465     LEU H    44
REMARK 465     HIS H    45
REMARK 465     ARG H    46
REMARK 465     PHE H    47
REMARK 465     VAL H    48
REMARK 465     LYS H    49
REMARK 465     TRP H    50
REMARK 465     PRO H    51
REMARK 465     LYS H    52
REMARK 465     VAL H    53
REMARK 465     VAL H    54
REMARK 465     ARG H    55
REMARK 465     ILE H    56
REMARK 465     GLN H    57
REMARK 465     ASN P   195
REMARK 465     GLN P   196
REMARK 465     THR P   197
REMARK 465     VAL P   198
REMARK 465     SER P   199
REMARK 465     LEU P   200
REMARK 465     ARG P   201
REMARK 465     ARG P   202
REMARK 465     TYR P   203
REMARK 465     ARG P   204
REMARK 465     LYS R   164
REMARK 465     PRO R   165
REMARK 465     TYR R   166
REMARK 465     VAL R   167
REMARK 465     ARG R   168
REMARK 465     SER R   169
REMARK 465     LYS R   170
REMARK 465     GLY R   171
REMARK 465     ARG R   172
REMARK 465     LYS R   173
REMARK 465     PHE R   174
REMARK 465     GLU R   175
REMARK 465     LYS R   176
REMARK 465     VAL R   177
REMARK 465     ARG R   178
REMARK 465     GLY R   179
REMARK 465     ARG R   180
REMARK 465     ARG R   181
REMARK 465     ASN R   182
REMARK 465     SER R   183
REMARK 465     ARG R   184
REMARK 465     GLY R   185
REMARK 465     PHE R   186
REMARK 465     LYS R   187
REMARK 465     VAL R   188
REMARK 465     THR T   190
REMARK 465     SER T   191
REMARK 465     THR T   192
REMARK 465     SER T   193
REMARK 465     GLY T   194
REMARK 465     CYS T   195
REMARK 465     SER T   196
REMARK 465     SER T   197
REMARK 465     SER T   198
REMARK 465     CYS T   199
REMARK 465     GLY T   200
REMARK 465     THR T   201
REMARK 465     LYS T   202
REMARK 465     GLU T   203
REMARK 465     GLY T   204
REMARK 465     GLN T   205
REMARK 465     GLU T   206
REMARK 465     VAL T   207
REMARK 465     LYS T   208
REMARK 465     PHE T   209
REMARK 465     MET X     1
REMARK 465     ALA X     2
REMARK 465     PRO X     3
REMARK 465     LYS X     4
REMARK 465     ALA X     5
REMARK 465     ALA X     6
REMARK 465     VAL X     7
REMARK 465     LYS X     8
REMARK 465     LYS X     9
REMARK 465     ALA X    10
REMARK 465     ASP X    11
REMARK 465     GLY X    12
REMARK 465     LYS X    13
REMARK 465     THR X    14
REMARK 465     GLN X    15
REMARK 465     GLN X    16
REMARK 465     ALA X    17
REMARK 465     LEU X    18
REMARK 465     LYS X    19
REMARK 465     VAL X    20
REMARK 465     ALA X    21
REMARK 465     LYS X    22
REMARK 465     ALA X    23
REMARK 465     VAL X    24
REMARK 465     LYS X    25
REMARK 465     SER X    26
REMARK 465     GLY X    27
REMARK 465     SER X    28
REMARK 465     ILE X    29
REMARK 465     LYS X    30
REMARK 465     THR Z    76
REMARK 465     THR Z    77
REMARK 465     LYS Z    78
REMARK 465     LYS Z    79
REMARK 465     PRO Z    80
REMARK 465     TYR Z    81
REMARK 465     SER Z    82
REMARK 465     ARG Z    83
REMARK 465     SER Z    84
REMARK 465     ILE Z    85
REMARK 465     VAL Z    86
REMARK 465     GLY Z    87
REMARK 465     ALA Z    88
REMARK 465     THR Z    89
REMARK 465     LEU Z    90
REMARK 465     GLU Z    91
REMARK 465     VAL Z    92
REMARK 465     ILE Z    93
REMARK 465     GLN Z    94
REMARK 465     LYS Z    95
REMARK 465     LYS Z    96
REMARK 465     ARG Z    97
REMARK 465     SER Z    98
REMARK 465     GLU Z    99
REMARK 465     LYS Z   100
REMARK 465     PRO Z   101
REMARK 465     GLU Z   102
REMARK 465     VAL Z   103
REMARK 465     ARG Z   104
REMARK 465     ASP Z   105
REMARK 465     ALA Z   106
REMARK 465     ALA Z   107
REMARK 465     ARG Z   108
REMARK 465     GLU Z   109
REMARK 465     ALA Z   110
REMARK 465     ALA Z   111
REMARK 465     LEU Z   112
REMARK 465     ARG Z   113
REMARK 465     GLU Z   114
REMARK 465     ILE Z   115
REMARK 465     LYS Z   116
REMARK 465     GLU Z   117
REMARK 465     ARG Z   118
REMARK 465     ILE Z   119
REMARK 465     LYS Z   120
REMARK 465     LYS Z   121
REMARK 465     THR Z   122
REMARK 465     LYS Z   123
REMARK 465     ASP Z   124
REMARK 465     GLU Z   125
REMARK 465     LYS Z   126
REMARK 465     LYS Z   127
REMARK 465     ALA Z   128
REMARK 465     LYS Z   129
REMARK 465     LYS Z   130
REMARK 465     ALA Z   131
REMARK 465     GLU Z   132
REMARK 465     VAL Z   133
REMARK 465     ALA Z   134
REMARK 465     LYS Z   135
REMARK 465     SER Z   136
REMARK 465     GLN Z   137
REMARK 465     LYS Z   138
REMARK 465     THR Z   139
REMARK 465     GLN Z   140
REMARK 465     SER Z   141
REMARK 465     LYS Z   142
REMARK 465     GLY Z   143
REMARK 465     GLY Z   144
REMARK 465     ALA Z   145
REMARK 465     THR Z   146
REMARK 465     GLN Z   147
REMARK 465     ARG Z   148
REMARK 465     GLY Z   149
REMARK 465     ALA Z   150
REMARK 465     LYS Z   151
REMARK 465     GLY Z   152
REMARK 465     PRO Z   153
REMARK 465     LYS Z   154
REMARK 465     ILE Z   155
REMARK 465     GLY Z   156
REMARK 465     GLY Z   157
REMARK 465     GLY Z   158
REMARK 465     GLY Z   159
REMARK 465     GLY Z   160
REMARK 465     LYS Z   161
REMARK 465     ARG Z   162
REMARK 465     LYS Y   131
REMARK 465     GLY Y   132
REMARK 465     LYS Y   133
REMARK 465     PHE Y   134
REMARK 465     THR Y   135
REMARK 465     ALA Y   136
REMARK 465     GLU Y   137
REMARK 465     ASP Y   138
REMARK 465     VAL Y   139
REMARK 465     ALA Y   140
REMARK 465     ALA Y   141
REMARK 465     ALA Y   142
REMARK 465     GLY Y   143
REMARK 465     ALA Y   144
REMARK 465     SER Y   145
REMARK 465     LEU Y   146
REMARK 465     GLN Y   147
REMARK 465     GLU Y   148
REMARK 465     ILE Y   149
REMARK 465     ASP Y   150
REMARK 465     MET b     2
REMARK 465     ALA b     3
REMARK 465     THR b     4
REMARK 465     VAL b     5
REMARK 465     PRO b     6
REMARK 465     GLU b     7
REMARK 465     PRO b     8
REMARK 465     LEU b     9
REMARK 465     ILE b    10
REMARK 465     TRP b    11
REMARK 465     GLU b    12
REMARK 465     ILE b    13
REMARK 465     VAL b    14
REMARK 465     LYS b    15
REMARK 465     LYS b    16
REMARK 465     ASN b    17
REMARK 465     ASN b    18
REMARK 465     CYS b    19
REMARK 465     PHE b    20
REMARK 465     LEU b    21
REMARK 465     VAL b    22
REMARK 465     LYS b    23
REMARK 465     GLN b    24
REMARK 465     PHE b    25
REMARK 465     GLY b    26
REMARK 465     ASN b    27
REMARK 465     SER b    28
REMARK 465     ASN b    29
REMARK 465     ALA b    30
REMARK 465     LYS b    31
REMARK 465     VAL b    32
REMARK 465     GLN b    33
REMARK 465     PHE b    34
REMARK 465     THR b    35
REMARK 465     LYS b    36
REMARK 465     GLU b    37
REMARK 465     PRO b    38
REMARK 465     ASN b    39
REMARK 465     ASN b    40
REMARK 465     LEU b    41
REMARK 465     TYR b    42
REMARK 465     ASN b    43
REMARK 465     VAL b    44
REMARK 465     HIS b    45
REMARK 465     SER b    46
REMARK 465     TYR b    47
REMARK 465     LYS b    48
REMARK 465     HIS b    49
REMARK 465     SER b    50
REMARK 465     GLY b    51
REMARK 465     LEU b    52
REMARK 465     ALA b    53
REMARK 465     ASN b    54
REMARK 465     LYS b    55
REMARK 465     LYS b    56
REMARK 465     THR b    57
REMARK 465     LEU b   131
REMARK 465     GLN b   132
REMARK 465     VAL b   133
REMARK 465     SER b   134
REMARK 465     LYS b   135
REMARK 465     SER b   136
REMARK 465     GLY b   137
REMARK 465     ALA b   138
REMARK 465     LYS b   139
REMARK 465     LYS b   140
REMARK 465     LYS b   141
REMARK 465     ASN b   142
REMARK 465     ARG b   143
REMARK 465     GLN b   144
REMARK 465     PRO b   145
REMARK 465     THR b   146
REMARK 465     LYS b   147
REMARK 465     LEU b   148
REMARK 465     MET d     1
REMARK 465     ALA d     2
REMARK 465     LYS d     3
REMARK 465     SER d     4
REMARK 465     LYS d     5
REMARK 465     ASN d     6
REMARK 465     HIS d     7
REMARK 465     THR d     8
REMARK 465     ALA d     9
REMARK 465     HIS d    10
REMARK 465     ASN d    11
REMARK 465     GLN d    12
REMARK 465     SER d    13
REMARK 465     TYR d    14
REMARK 465     LYS d    15
REMARK 465     ALA d    16
REMARK 465     HIS d    17
REMARK 465     LYS d    18
REMARK 465     ASN d    19
REMARK 465     GLY d    20
REMARK 465     ILE d    21
REMARK 465     LYS d    22
REMARK 465     LYS d    23
REMARK 465     PRO d    24
REMARK 465     LYS d    25
REMARK 465     ARG d    26
REMARK 465     HIS d    27
REMARK 465     ARG d    28
REMARK 465     GLN d    29
REMARK 465     THR d    30
REMARK 465     SER d    31
REMARK 465     THR d    32
REMARK 465     LYS d    33
REMARK 465     GLY d    34
REMARK 465     MET d    35
REMARK 465     ASP d    36
REMARK 465     PRO d    37
REMARK 465     ASP g   121
REMARK 465     GLU g   122
REMARK 465     GLU g   123
REMARK 465     UNK L    12
REMARK 465     THR S   168
REMARK 465     PHE S   169
REMARK 465     LYS S   170
REMARK 465     ALA S   171
REMARK 465     SER S   172
REMARK 465     ARG S   173
REMARK 465     PRO S   174
REMARK 465     ASN S   175
REMARK 465     LEU S   176
REMARK 465     PHE S   177
REMARK 465     MET S   178
REMARK 465     MET W     1
REMARK 465     ALA W     2
REMARK 465     ARG W     3
REMARK 465     GLY W     4
REMARK 465     VAL W     5
REMARK 465     ALA W     6
REMARK 465     VAL W     7
REMARK 465     ALA W     8
REMARK 465     ALA W     9
REMARK 465     LYS W    10
REMARK 465     GLY W    11
REMARK 465     GLY W    12
REMARK 465     ALA W    13
REMARK 465     ALA W   122
REMARK 465     GLU W   123
REMARK 465     ASN W   124
REMARK 465     GLU W   125
REMARK 465     GLY W   126
REMARK 465     GLU W   127
REMARK 465     GLU W   128
REMARK 465     GLU W   129
REMARK 465     ASP W   130
REMARK 465     ALA a   100
REMARK 465     LEU a   101
REMARK 465     ALA a   102
REMARK 465     THR a   103
REMARK 465     ARG a   104
REMARK 465     ASP a   105
REMARK 465     LYS a   106
REMARK 465     LYS a   107
REMARK 465     VAL a   108
REMARK 465     ALA a   109
REMARK 465     ALA a   110
REMARK 465     CYS a   111
REMARK 465     LYS a   112
REMARK 465     SER a   113
REMARK 465     ALA a   114
REMARK 465     LYS a   115
REMARK 465     ALA a   116
REMARK 465     ARG a   117
REMARK 465     LEU a   118
REMARK 465     GLU a   119
REMARK 465     ASP a   120
REMARK 465     ARG a   121
REMARK 465     PHE a   122
REMARK 465     LYS a   123
REMARK 465     THR a   124
REMARK 465     GLY a   125
REMARK 465     LYS a   126
REMARK 465     ASN a   127
REMARK 465     ARG a   128
REMARK 465     TRP a   129
REMARK 465     PHE a   130
REMARK 465     PHE a   131
REMARK 465     THR a   132
REMARK 465     LYS a   133
REMARK 465     LEU a   134
REMARK 465     ARG a   135
REMARK 465     PHE a   136
REMARK 465     PHE j   105
REMARK 465     MET j   106
REMARK 465     TYR j   107
REMARK 465     PRO j   108
REMARK 465     SER j   109
REMARK 465     SER j   110
REMARK 465     ILE j   111
REMARK 465     MET k     1
REMARK 465     ALA k     2
REMARK 465     PRO k     3
REMARK 465     SER k     4
REMARK 465     GLN k     5
REMARK 465     PRO k     6
REMARK 465     LYS k     7
REMARK 465     SER k     8
REMARK 465     GLY k     9
REMARK 465     LEU k    10
REMARK 465     PHE k    11
REMARK 465     VAL k    12
REMARK 465     GLY k    13
REMARK 465     ILE k    14
REMARK 465     ASN k    15
REMARK 465     LYS k    16
REMARK 465     GLY k    17
REMARK 465     HIS k    18
REMARK 465     VAL k    19
REMARK 465     VAL k    20
REMARK 465     THR k    21
REMARK 465     LYS k    22
REMARK 465     ARG k    23
REMARK 465     GLU k    24
REMARK 465     LEU k    25
REMARK 465     PRO k    26
REMARK 465     PRO k    27
REMARK 465     ARG k    28
REMARK 465     PRO k    29
REMARK 465     SER k    30
REMARK 465     ASP k    31
REMARK 465     ARG k    32
REMARK 465     LYS k    33
REMARK 465     GLY k    34
REMARK 465     LYS k    35
REMARK 465     ILE p     1
REMARK 465     ILE p     2
REMARK 465     GLU p     3
REMARK 465     PRO p     4
REMARK 465     SER p     5
REMARK 465     LEU p     6
REMARK 465     GLN p     7
REMARK 465     ALA p     8
REMARK 465     LEU p     9
REMARK 465     ALA p    10
REMARK 465     ARG p    11
REMARK 465     LYS p    12
REMARK 465     MET J     1
REMARK 465     PRO J     2
REMARK 465     PRO J     3
REMARK 465     LYS J     4
REMARK 465     LEU J     5
REMARK 465     ASP J     6
REMARK 465     PRO J     7
REMARK 465     THR J     8
REMARK 465     GLN J     9
REMARK 465     VAL J    10
REMARK 465     VAL J    11
REMARK 465     VAL J   140
REMARK 465     GLY J   141
REMARK 465     CYS J   142
REMARK 465     THR J   143
REMARK 465     VAL J   144
REMARK 465     ASP J   145
REMARK 465     GLY J   146
REMARK 465     LYS J   147
REMARK 465     ASP J   148
REMARK 465     PRO J   149
REMARK 465     LYS J   150
REMARK 465     ASP J   151
REMARK 465     LEU J   152
REMARK 465     GLN J   153
REMARK 465     GLN J   154
REMARK 465     GLU J   155
REMARK 465     ILE J   156
REMARK 465     SER J   157
REMARK 465     ASP J   158
REMARK 465     GLY J   159
REMARK 465     GLU J   160
REMARK 465     VAL J   161
REMARK 465     GLU J   162
REMARK 465     ILE J   163
REMARK 465     PRO J   164
REMARK 465     SER J   165
REMARK 465     ALA J   166
REMARK 465     MET t     1
REMARK 465     SER t     2
REMARK 465     SER t     3
REMARK 465     SER t     4
REMARK 465     GLU t     5
REMARK 465     SER t    64
REMARK 465     GLY t    65
REMARK 465     GLY t    66
REMARK 465     GLY t    67
REMARK 465     GLY t    68
REMARK 465     ALA t    69
REMARK 465     PRO t    70
REMARK 465     ALA t    71
REMARK 465     ALA t    72
REMARK 465     ALA t    73
REMARK 465     ALA t    74
REMARK 465     ALA t    75
REMARK 465     ALA t    76
REMARK 465     PRO t    77
REMARK 465     ALA t    78
REMARK 465     ALA t    79
REMARK 465     GLY t    80
REMARK 465     GLY t    81
REMARK 465     ALA t    82
REMARK 465     ALA t    83
REMARK 465     ALA t    84
REMARK 465     ALA t    85
REMARK 465     GLU t    86
REMARK 465     GLU t    87
REMARK 465     LYS t    88
REMARK 465     LYS t    89
REMARK 465     GLU t    90
REMARK 465     GLU t    91
REMARK 465     LYS t    92
REMARK 465     LYS t    93
REMARK 465     GLU t    94
REMARK 465     GLU t    95
REMARK 465     ALA t    96
REMARK 465     LYS t    97
REMARK 465     GLU t    98
REMARK 465     GLU t    99
REMARK 465     SER t   100
REMARK 465     ASP t   101
REMARK 465     ASP t   102
REMARK 465     ASP t   103
REMARK 465     MET t   104
REMARK 465     GLY t   105
REMARK 465     PHE t   106
REMARK 465     SER t   107
REMARK 465     LEU t   108
REMARK 465     PHE t   109
REMARK 465     ASP t   110
REMARK 465     MET u     1
REMARK 465     SER u     2
REMARK 465     SER u     3
REMARK 465     SER u     4
REMARK 465     GLU u     5
REMARK 465     SER u    64
REMARK 465     GLY u    65
REMARK 465     GLY u    66
REMARK 465     GLY u    67
REMARK 465     GLY u    68
REMARK 465     ALA u    69
REMARK 465     PRO u    70
REMARK 465     ALA u    71
REMARK 465     ALA u    72
REMARK 465     ALA u    73
REMARK 465     ALA u    74
REMARK 465     ALA u    75
REMARK 465     ALA u    76
REMARK 465     PRO u    77
REMARK 465     ALA u    78
REMARK 465     ALA u    79
REMARK 465     GLY u    80
REMARK 465     GLY u    81
REMARK 465     ALA u    82
REMARK 465     ALA u    83
REMARK 465     ALA u    84
REMARK 465     ALA u    85
REMARK 465     GLU u    86
REMARK 465     GLU u    87
REMARK 465     LYS u    88
REMARK 465     LYS u    89
REMARK 465     GLU u    90
REMARK 465     GLU u    91
REMARK 465     LYS u    92
REMARK 465     LYS u    93
REMARK 465     GLU u    94
REMARK 465     GLU u    95
REMARK 465     ALA u    96
REMARK 465     LYS u    97
REMARK 465     GLU u    98
REMARK 465     GLU u    99
REMARK 465     SER u   100
REMARK 465     ASP u   101
REMARK 465     ASP u   102
REMARK 465     ASP u   103
REMARK 465     MET u   104
REMARK 465     GLY u   105
REMARK 465     PHE u   106
REMARK 465     SER u   107
REMARK 465     LEU u   108
REMARK 465     PHE u   109
REMARK 465     ASP u   110
REMARK 465     GLU v    60
REMARK 465     LYS v    61
REMARK 465     PHE v    62
REMARK 465     ALA v    63
REMARK 465     ALA v    64
REMARK 465     VAL v    65
REMARK 465     PRO v    66
REMARK 465     SER v    67
REMARK 465     GLY v    68
REMARK 465     GLY v    69
REMARK 465     GLY v    70
REMARK 465     GLY v    71
REMARK 465     VAL v    72
REMARK 465     ALA v    73
REMARK 465     VAL v    74
REMARK 465     SER v    75
REMARK 465     ALA v    76
REMARK 465     ALA v    77
REMARK 465     ALA v    78
REMARK 465     PRO v    79
REMARK 465     ALA v    80
REMARK 465     ALA v    81
REMARK 465     GLY v    82
REMARK 465     GLY v    83
REMARK 465     ALA v    84
REMARK 465     ALA v    85
REMARK 465     ALA v    86
REMARK 465     PRO v    87
REMARK 465     ALA v    88
REMARK 465     ALA v    89
REMARK 465     GLU v    90
REMARK 465     SER v    91
REMARK 465     LYS v    92
REMARK 465     LYS v    93
REMARK 465     GLU v    94
REMARK 465     GLU v    95
REMARK 465     LYS v    96
REMARK 465     VAL v    97
REMARK 465     VAL v    98
REMARK 465     GLU v    99
REMARK 465     LYS v   100
REMARK 465     GLU v   101
REMARK 465     GLU v   102
REMARK 465     SER v   103
REMARK 465     ASP v   104
REMARK 465     ASP v   105
REMARK 465     ASP v   106
REMARK 465     MET v   107
REMARK 465     GLY v   108
REMARK 465     PHE v   109
REMARK 465     SER v   110
REMARK 465     LEU v   111
REMARK 465     PHE v   112
REMARK 465     ASP v   113
REMARK 465     GLU w    60
REMARK 465     LYS w    61
REMARK 465     PHE w    62
REMARK 465     ALA w    63
REMARK 465     ALA w    64
REMARK 465     VAL w    65
REMARK 465     PRO w    66
REMARK 465     SER w    67
REMARK 465     GLY w    68
REMARK 465     GLY w    69
REMARK 465     GLY w    70
REMARK 465     GLY w    71
REMARK 465     VAL w    72
REMARK 465     ALA w    73
REMARK 465     VAL w    74
REMARK 465     SER w    75
REMARK 465     ALA w    76
REMARK 465     ALA w    77
REMARK 465     ALA w    78
REMARK 465     PRO w    79
REMARK 465     ALA w    80
REMARK 465     ALA w    81
REMARK 465     GLY w    82
REMARK 465     GLY w    83
REMARK 465     ALA w    84
REMARK 465     ALA w    85
REMARK 465     ALA w    86
REMARK 465     PRO w    87
REMARK 465     ALA w    88
REMARK 465     ALA w    89
REMARK 465     GLU w    90
REMARK 465     SER w    91
REMARK 465     LYS w    92
REMARK 465     LYS w    93
REMARK 465     GLU w    94
REMARK 465     GLU w    95
REMARK 465     LYS w    96
REMARK 465     VAL w    97
REMARK 465     VAL w    98
REMARK 465     GLU w    99
REMARK 465     LYS w   100
REMARK 465     GLU w   101
REMARK 465     GLU w   102
REMARK 465     SER w   103
REMARK 465     ASP w   104
REMARK 465     ASP w   105
REMARK 465     ASP w   106
REMARK 465     MET w   107
REMARK 465     GLY w   108
REMARK 465     PHE w   109
REMARK 465     SER w   110
REMARK 465     LEU w   111
REMARK 465     PHE w   112
REMARK 465     ASP w   113
REMARK 465     PRO s   263
REMARK 465     HIS s   264
REMARK 465     ALA s   265
REMARK 465     ASP s   266
REMARK 465     LYS s   267
REMARK 465     ILE s   268
REMARK 465     LYS s   269
REMARK 465     GLU s   270
REMARK 465     TYR s   271
REMARK 465     LEU s   272
REMARK 465     LYS s   273
REMARK 465     ASP s   274
REMARK 465     PRO s   275
REMARK 465     SER s   276
REMARK 465     LYS s   277
REMARK 465     PHE s   278
REMARK 465     ALA s   279
REMARK 465     VAL s   280
REMARK 465     ALA s   281
REMARK 465     ALA s   282
REMARK 465     PRO s   283
REMARK 465     VAL s   284
REMARK 465     ALA s   285
REMARK 465     ALA s   286
REMARK 465     ASP s   287
REMARK 465     SER s   288
REMARK 465     GLY s   289
REMARK 465     ALA s   290
REMARK 465     ALA s   291
REMARK 465     ALA s   292
REMARK 465     PRO s   293
REMARK 465     SER s   294
REMARK 465     ALA s   295
REMARK 465     ALA s   296
REMARK 465     LYS s   297
REMARK 465     GLU s   298
REMARK 465     GLU s   299
REMARK 465     GLU s   300
REMARK 465     LYS s   301
REMARK 465     LYS s   302
REMARK 465     GLU s   303
REMARK 465     GLU s   304
REMARK 465     PRO s   305
REMARK 465     GLU s   306
REMARK 465     GLU s   307
REMARK 465     GLU s   308
REMARK 465     SER s   309
REMARK 465     ASP s   310
REMARK 465     GLY s   311
REMARK 465     ASP s   312
REMARK 465     LEU s   313
REMARK 465     GLY s   314
REMARK 465     MET s   315
REMARK 465     SER s   316
REMARK 465     LEU s   317
REMARK 465     PHE s   318
REMARK 465     ASP s   319
REMARK 465     GLY D   270
REMARK 465     THR D   271
REMARK 465     PHE D   272
REMARK 465     GLU D   273
REMARK 465     ALA D   274
REMARK 465     PRO D   275
REMARK 465     SER D   276
REMARK 465     LEU D   277
REMARK 465     LYS D   278
REMARK 465     LYS D   279
REMARK 465     LYS D   280
REMARK 465     GLY D   281
REMARK 465     PHE D   282
REMARK 465     ILE D   283
REMARK 465     LEU D   284
REMARK 465     PRO D   285
REMARK 465     ARG D   286
REMARK 465     PRO D   287
REMARK 465     LYS D   288
REMARK 465     MET D   289
REMARK 465     ALA D   290
REMARK 465     ASN D   291
REMARK 465     ALA D   292
REMARK 465     ASP D   293
REMARK 465     LEU D   294
REMARK 465     GLY D   295
REMARK 465     ARG D   296
REMARK 465     ILE D   297
REMARK 465     ILE D   298
REMARK 465     ASN D   299
REMARK 465     SER D   300
REMARK 465     ASP D   301
REMARK 465     GLU D   302
REMARK 465     LYS I   185
REMARK 465     ALA I   186
REMARK 465     GLU I   187
REMARK 465     GLY I   188
REMARK 465     ARG I   189
REMARK 465     ILE I   190
REMARK 465     MET I   191
REMARK 465     SER I   192
REMARK 465     ASP I   193
REMARK 465     GLY I   194
REMARK 465     VAL I   195
REMARK 465     ASN I   196
REMARK 465     ALA I   197
REMARK 465     GLN I   198
REMARK 465     LEU I   199
REMARK 465     LEU I   200
REMARK 465     GLY I   201
REMARK 465     SER I   202
REMARK 465     HIS I   203
REMARK 465     GLY I   204
REMARK 465     ARG I   205
REMARK 465     LEU I   206
REMARK 465     ALA I   207
REMARK 465     LYS I   208
REMARK 465     ARG I   209
REMARK 465     ALA I   210
REMARK 465     PRO I   211
REMARK 465     GLY I   212
REMARK 465     LYS I   213
REMARK 465     ALA I   214
REMARK 465     PHE I   215
REMARK 465     LEU I   216
REMARK 465     ALA I   217
REMARK 465     GLU I   218
REMARK 465     THR I   219
REMARK 465     ILE I   220
REMARK 465     GLN I   221
REMARK 465     ALA I   222
REMARK 465     SER I   223
REMARK 465     ALA I   224
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470   M RES CSSEQI  ATOMS
REMARK 470     GLN B 249    CB   CG   CD   OE1  NE2
REMARK 470     ALA B 250    CB
REMARK 470     ALA B 251    CB
REMARK 470     ALA B 252    CB
REMARK 470     THR B 253    CB   OG1  CG2
REMARK 470     ALA B 254    CB
REMARK 470     ALA B 255    CB
REMARK 470     GLU E  92    CG   CD   OE1  OE2
REMARK 470     ALA H 115    CB
REMARK 470     GLU H 116    CB   CG   CD   OE1  OE2
REMARK 470     LYS H 118    CB   CG   CD   CE   NZ
REMARK 470     THR H 119    CB   OG1  CG2
REMARK 470     VAL H 120    CB   CG1  CG2
REMARK 470     GLU H 121    CB   CG   CD   OE1  OE2
REMARK 470     ALA H 122    CB
REMARK 470     LYS H 123    CB   CG   CD   CE   NZ
REMARK 470     ARG H 256    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     MET H 257    CB   CG   SD   CE
REMARK 470     THR H 258    CB   OG1  CG2
REMARK 470     MET M   1    CB   CG   SD   CE
REMARK 470     SER M   2    CB   OG
REMARK 470     LYS M   3    CB   CG   CD   CE   NZ
REMARK 470     ARG M   4    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     ARG M   6    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     SER M   9    CB   OG
REMARK 470     ALA M  10    CB
REMARK 470     SER O  65    CB   OG
REMARK 470     ASN O  66    CB   CG   OD1  ND2
REMARK 470     ARG O  67    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     PHE O  68    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     HIS O  69    CB   CG   ND1  CD2  CE1  NE2
REMARK 470     CYS O  70    CB   SG
REMARK 470     ARG Q 114    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     LEU Q 116    CB   CG   CD1  CD2
REMARK 470     ASP Q 117    CB   CG   OD1  OD2
REMARK 470     GLN Q 118    CB   CG   CD   OE1  NE2
REMARK 470     GLU Q 138    CB   CG   CD   OE1  OE2
REMARK 470     ARG Q 139    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     ARG Q 140    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     PRO Q 141    CB   CG   CD
REMARK 470     PHE Q 142    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     MET U   1    CB   CG   SD   CE
REMARK 470     PRO U   2    CB   CG   CD
REMARK 470     ALA U   3    CB
REMARK 470     HIS U   5    CB   CG   ND1  CD2  CE1  NE2
REMARK 470     LEU U   7    CB   CG   CD1  CD2
REMARK 470     ARG U   8    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     PRO U 135    CB   CG   CD
REMARK 470     LYS U 136    CB   CG   CD   CE   NZ
REMARK 470     PRO U 137    CB   CG   CD
REMARK 470     PHE U 139    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     MET U 140    CB   CG   SD   CE
REMARK 470     VAL U 141    CB   CG1  CG2
REMARK 470     GLU V 155    CD   OE1  OE2
REMARK 470     PRO V 162    CB   CG   CD
REMARK 470     GLU V 163    CB   CG   CD   OE1  OE2
REMARK 470     SER V 164    CB   OG
REMARK 470     GLN V 165    CB   CG   CD   OE1  NE2
REMARK 470     ILE V 166    CB   CG1  CG2  CD1
REMARK 470     ALA V 167    CB
REMARK 470     ALA V 168    CB
REMARK 470     ARG V 169    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     LYS V 170    CB   CG   CD   CE   NZ
REMARK 470     ALA V 171    CB
REMARK 470     MET Z   1    CB   CG   SD   CE
REMARK 470     VAL Z   2    CB   CG1  CG2
REMARK 470     LEU Z   3    CB   CG   CD1  CD2
REMARK 470     LYS Z   4    CB   CG   CD   CE   NZ
REMARK 470     THR Z   5    CB   OG1  CG2
REMARK 470     HIS Z  61    CB   CG   ND1  CD2  CE1  NE2
REMARK 470     LYS Z  62    CB   CG   CD   CE   NZ
REMARK 470     LYS Z  63    CB   CG   CD   CE   NZ
REMARK 470     ASP Z  64    CB   CG   OD1  OD2
REMARK 470     ILE Z  65    CB   CG1  CG2  CD1
REMARK 470     ARG Z  74    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     ARG Z  75    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     MET f   1    CB   CG   SD   CE
REMARK 470     ALA f   2    CB
REMARK 470     PRO f   3    CB   CG   CD
REMARK 470     THR f   4    CB   OG1  CG2
REMARK 470     LYS f   5    CB   CG   CD   CE   NZ
REMARK 470     LYS f   6    CB   CG   CD   CE   NZ
REMARK 470     THR f 110    CB   OG1  CG2
REMARK 470     THR f 111    CB   OG1  CG2
REMARK 470     GLN f 112    CB   CG   CD   OE1  NE2
REMARK 470     LYS g 117    CB   CG   CD   CE   NZ
REMARK 470     VAL g 118    CB   CG1  CG2
REMARK 470     VAL g 119    CB   CG1  CG2
REMARK 470     GLU g 120    CB   CG   CD   OE1  OE2
REMARK 470     GLU h 131    CB   CG   CD   OE1  OE2
REMARK 470     ASP h 132    CB   CG   OD1  OD2
REMARK 470     GLU h 133    CB   CG   CD   OE1  OE2
REMARK 470     PRO l  86    CB   CG   CD
REMARK 470     ARG l  87    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     LYS l  88    CB   CG   CD   CE   NZ
REMARK 470     ARG l  89    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     ALA l  90    CB
REMARK 470     ALA l  91    CB
REMARK 470     ALA l  92    CB
REMARK 470     ALA l  93    CB
REMARK 470     ASN l  94    CB   CG   OD1  ND2
REMARK 470     MET n   1    CB   CG   SD   CE
REMARK 470     PRO n   2    CB   CG   CD
REMARK 470     LYS n   3    CB   CG   CD   CE   NZ
REMARK 470     GLN n   4    CB   CG   CD   OE1  NE2
REMARK 470     SER r 103    CB   OG
REMARK 470     LEU r 104    CB   CG   CD1  CD2
REMARK 470     PHE r 105    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     TYR G  88    OH
REMARK 470     LYS W  16    CB   CG   CD   CE   NZ
REMARK 470     LYS W  17    CB   CG   CD   CE   NZ
REMARK 470     PHE W 119    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     ASN W 120    CB   CG   OD1  ND2
REMARK 470     ILE W 121    CB   CG1  CG2  CD1
REMARK 470     MET a   1    CB   CG   SD   CE
REMARK 470     VAL a   2    CB   CG1  CG2
REMARK 470     LYS a   3    CB   CG   CD   CE   NZ
REMARK 470     PHE a   4    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     LEU a   5    CB   CG   CD1  CD2
REMARK 470     LYS a   6    CB   CG   CD   CE   NZ
REMARK 470     ALA a  47    CB
REMARK 470     LYS a  48    CB   CG   CD   CE   NZ
REMARK 470     TYR a  49    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     TYR a  49    OH
REMARK 470     PRO a  50    CB   CG   CD
REMARK 470     LYS a  51    CB   CG   CD   CE   NZ
REMARK 470     THR i  25    CB   OG1  CG2
REMARK 470     PRO i  26    CB   CG   CD
REMARK 470     LYS j  58    CB   CG   CD   CE   NZ
REMARK 470     ALA j  59    CB
REMARK 470     LYS j  60    CB   CG   CD   CE   NZ
REMARK 470     THR j  61    CB   OG1  CG2
REMARK 470     LYS j  62    CB   CG   CD   CE   NZ
REMARK 470     SER j  63    CB   OG
REMARK 470     ASN j  64    CB   CG   OD1  ND2
REMARK 470     ASP j  65    CB   CG   OD1  OD2
REMARK 470     ASN j  81    CB   CG   OD1  ND2
REMARK 470     SER j  82    CB   OG
REMARK 470     MET J 122    CE
REMARK 470     MET c   1    CB   CG   SD   CE
REMARK 470     SER c   2    CB   OG
REMARK 470     HIS C  11    CB   CG   ND1  CD2  CE1  NE2
REMARK 470     SER C  13    CB   OG
REMARK 470     LEU C  14    CB   CG   CD1  CD2
REMARK 470     TYR C 384    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     TYR C 384    OH
REMARK 470     ARG C 386    CB   CG   CD   NE   CZ   NH1  NH2
REMARK 470     LEU C 387    CB   CG   CD1  CD2
REMARK 470     LYS C 388    CB   CG   CD   CE   NZ
REMARK 470     ALA C 389    CB
REMARK 470     MET D   1    CB   CG   SD   CE
REMARK 470     ALA D   2    CB
REMARK 470     THR D   3    CB   OG1  CG2
REMARK 470     GLN D   4    CB   CG   CD   OE1  NE2
REMARK 470     THR D   5    CB   OG1  CG2
REMARK 470     ASP D  17    CB   CG   OD1  OD2
REMARK 470     MET D  18    CB   CG   SD   CE
REMARK 470     ALA D  19    CB
REMARK 470     THR D  20    CB   OG1  CG2
REMARK 470     ASP D  21    CB   CG   OD1  OD2
REMARK 470     ASP I  83    CB   CG   OD1  OD2
REMARK 470     ALA I  84    CB
REMARK 470     PHE I  85    CB   CG   CD1  CD2  CE1  CE2  CZ
REMARK 470     HIS I  86    CB   CG   ND1  CD2  CE1  NE2
REMARK 470     LEU I  87    CB   CG   CD1  CD2
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE
REMARK 500   O    VAL Q   124     N    GLU Q   125              1.30
REMARK 500   O    ASP Q   137     N    GLU Q   138              1.30
REMARK 500   O    VAL H   233     N    MET H   234              1.30
REMARK 500   O    TYR j    12     N    VAL j    13              1.31
REMARK 500   O    GLN D   304     N    SER D   305              1.31
REMARK 500   O    UNK L   146     N    UNK L   147              1.32
REMARK 500   O    LEU C    17     N    PRO C    18              1.32
REMARK 500   O    GLY D    94     N    ALA D    95              1.32
REMARK 500   O    ARG C   352     N    LEU C   353              1.34
REMARK 500   O    ILE V    36     N    ARG V    37              1.34
REMARK 500   O    ALA D   329     N    VAL D   330              1.34
REMARK 500   O    GLY r   101     N    THR r   102              1.34
REMARK 500   O    PRO P    74     N    VAL P    75              1.34
REMARK 500   O    HIS O    40     N    HIS O    41              1.34
REMARK 500   O    GLY Q   235     N    MET Q   236              1.34
REMARK 500   O    ARG q    23     N    SER q    24              1.34
REMARK 500   O    SER Q   290     N    SER Q   291              1.34
REMARK 500   O    GLY C   385     N    ARG C   386              1.35
REMARK 500   O    GLY C   292     N    GLN C   293              1.35
REMARK 500   O    UNK L   103     N    UNK L   104              1.36
REMARK 500   O    LYS F     2     N    THR F     3              1.36
REMARK 500   O    THR G    79     N    VAL G    80              1.36
REMARK 500   O    ALA D    95     N    PHE D    96              1.36
REMARK 500   O    GLU Q   237     N    SER Q   238              1.36
REMARK 500   O    VAL n    47     N    PHE n    48              1.37
REMARK 500   O    SER C   295     N    HIS C   296              1.37
REMARK 500   O    ILE U   126     N    SER U   127              1.37
REMARK 500   O    UNK L   128     N    UNK L   129              1.37
REMARK 500   O    LEU e   204     N    TRP e   205              1.37
REMARK 500   O    TRP B   196     N    PRO B   197              1.37
REMARK 500   O    GLY C   372     N    ARG C   373              1.37
REMARK 500   O    ALA D   328     N    ALA D   329              1.37
REMARK 500   O    TRP Z    53     N    THR Z    54              1.37
REMARK 500   O    LYS C   120     N    ASN C   121              1.38
REMARK 500   O    LYS V   170     N    ALA V   171              1.38
REMARK 500   O    SER Q   238     N    LEU Q   239              1.38
REMARK 500   O    ARG D    90     N    ALA D    91              1.38
REMARK 500   O    LYS O   127     N    VAL O   128              1.38
REMARK 500   O    MET C     1     N    SER C     2              1.38
REMARK 500   O    UNK x     3     N    UNK x     4              1.38
REMARK 500   O    PHE C   130     N    THR C   131              1.39
REMARK 500   O    MET k    93     N    SER k    94              1.39
REMARK 500   OD1  ASP t    18     CD   LYS v     2              1.39
REMARK 500   O    GLN C   349     N    THR C   350              1.39
REMARK 500   O    SER Y     9     N    SER Y    10              1.39
REMARK 500   O    PRO D    84     N    GLY D    85              1.39
REMARK 500   O    THR D    20     N    ASP D    21              1.39
REMARK 500   O    ARG K    11     N    VAL K    12              1.39
REMARK 500   O    ALA Q   249     N    ASP Q   250              1.39
REMARK 500   O    UNK z     2     N    UNK z     3              1.40
REMARK 500
REMARK 500 THIS ENTRY HAS     156 CLOSE CONTACTS
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION
REMARK 500    TYR A  83   CB    TYR A  83   CG     -0.099
REMARK 500    VAL A 200   N     VAL A 200   CA      0.129
REMARK 500    ARG B  68   NE    ARG B  68   CZ      0.094
REMARK 500    LYS B  73   C     LYS B  73   O      -0.162
REMARK 500    SER B 152   CA    SER B 152   CB      0.098
REMARK 500    TYR B 186   CE1   TYR B 186   CZ      0.084
REMARK 500    TRP B 196   C     TRP B 196   O      -0.215
REMARK 500    PRO B 197   CA    PRO B 197   CB     -0.112
REMARK 500    TRP B 196   C     PRO B 197   N       0.124
REMARK 500    HIS B 209   C     PRO B 210   N       0.129
REMARK 500    SER B 223   CA    SER B 223   CB      0.097
REMARK 500    ARG B 247   CZ    ARG B 247   NH2     0.094
REMARK 500    ARG E  34   CA    ARG E  34   CB      0.232
REMARK 500    ARG E  34   CB    ARG E  34   CG      0.171
REMARK 500    ARG E  34   CG    ARG E  34   CD      0.178
REMARK 500    LYS E  89   N     LYS E  89   CA      0.162
REMARK 500    TYR E  91   CG    TYR E  91   CD2     0.419
REMARK 500    TYR E  91   CG    TYR E  91   CD1     0.397
REMARK 500    TYR E  91   CD1   TYR E  91   CE1     0.388
REMARK 500    TYR E  91   CE1   TYR E  91   CZ      0.398
REMARK 500    TYR E  91   CZ    TYR E  91   CE2     0.422
REMARK 500    TYR E  91   CE2   TYR E  91   CD2     0.366
REMARK 500    GLY E 115   CA    GLY E 115   C      -0.185
REMARK 500    MET E 116   N     MET E 116   CA     -0.155
REMARK 500    ARG E 143   CD    ARG E 143   NE      0.103
REMARK 500    HIS E 153   CG    HIS E 153   CD2     0.375
REMARK 500    HIS E 153   CG    HIS E 153   ND1     0.270
REMARK 500    HIS E 153   ND1   HIS E 153   CE1     0.265
REMARK 500    HIS E 153   CE1   HIS E 153   NE2     0.280
REMARK 500    HIS E 153   NE2   HIS E 153   CD2     0.286
REMARK 500    LYS F   2   C     LYS F   2   O      -0.127
REMARK 500    ARG F  88   CD    ARG F  88   NE      0.127
REMARK 500    TYR F  95   CZ    TYR F  95   OH      0.120
REMARK 500    THR F 187   C     THR F 187   O      -0.197
REMARK 500    GLU F 188   N     GLU F 188   CA      0.196
REMARK 500    ARG H  61   CD    ARG H  61   NE      0.103
REMARK 500    ASN H  87   N     ASN H  87   CA     -0.174
REMARK 500    ASN H  87   C     ASN H  87   O      -0.138
REMARK 500    ARG H 226   CZ    ARG H 226   NH2     0.080
REMARK 500    VAL H 233   C     VAL H 233   O      -0.159
REMARK 500    PRO M  53   N     PRO M  53   CA     -0.111
REMARK 500    GLY M  68   CA    GLY M  68   C       0.157
REMARK 500    LYS M  69   N     LYS M  69   CA      0.132
REMARK 500    LEU M  72   C     ARG M  73   N       0.141
REMARK 500    PRO P  42   CD    PRO P  42   N      -0.104
REMARK 500    ARG P  49   CD    ARG P  49   NE      0.102
REMARK 500    PRO P  74   CA    PRO P  74   CB     -0.142
REMARK 500    PRO P  74   C     PRO P  74   O      -0.274
REMARK 500    PHE P  94   CG    PHE P  94   CD1     0.091
REMARK 500    ARG P 143   NE    ARG P 143   CZ      0.086
REMARK 500
REMARK 500 THIS ENTRY HAS     289 BOND DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3
REMARK 500    ALA A  12   CB  -  CA  -  C   ANGL. DEV. =  13.1 DEGREES
REMARK 500    ARG A  21   NE  -  CZ  -  NH1 ANGL. DEV. =   3.9 DEGREES
REMARK 500    ARG A  21   NE  -  CZ  -  NH2 ANGL. DEV. =  -5.2 DEGREES
REMARK 500    ARG A  25   CB  -  CA  -  C   ANGL. DEV. = -12.2 DEGREES
REMARK 500    ARG A  25   NE  -  CZ  -  NH2 ANGL. DEV. =  -3.0 DEGREES
REMARK 500    PHE A  27   N   -  CA  -  CB  ANGL. DEV. = -11.8 DEGREES
REMARK 500    LEU A  33   CA  -  CB  -  CG  ANGL. DEV. =  14.8 DEGREES
REMARK 500    PRO A  55   C   -  N   -  CD  ANGL. DEV. = -13.7 DEGREES
REMARK 500    TYR A  83   CA  -  CB  -  CG  ANGL. DEV. = -16.5 DEGREES
REMARK 500    TYR A  83   CD1 -  CG  -  CD2 ANGL. DEV. =   7.7 DEGREES
REMARK 500    TYR A  83   CB  -  CG  -  CD1 ANGL. DEV. =  -5.3 DEGREES
REMARK 500    TYR A  83   CG  -  CD1 -  CE1 ANGL. DEV. =  -5.2 DEGREES
REMARK 500    TYR A  83   CG  -  CD2 -  CE2 ANGL. DEV. =  -5.0 DEGREES
REMARK 500    ILE A 119   CA  -  C   -  N   ANGL. DEV. =  17.3 DEGREES
REMARK 500    ARG A 121   CB  -  CA  -  C   ANGL. DEV. =  13.3 DEGREES
REMARK 500    ARG A 201   NE  -  CZ  -  NH1 ANGL. DEV. =  -6.1 DEGREES
REMARK 500    LYS A 211   N   -  CA  -  CB  ANGL. DEV. = -12.2 DEGREES
REMARK 500    ARG A 214   NE  -  CZ  -  NH2 ANGL. DEV. =   4.8 DEGREES
REMARK 500    ARG B   9   NH1 -  CZ  -  NH2 ANGL. DEV. =  -7.8 DEGREES
REMARK 500    ARG B   9   NE  -  CZ  -  NH1 ANGL. DEV. =   3.4 DEGREES
REMARK 500    ARG B   9   NE  -  CZ  -  NH2 ANGL. DEV. =   4.1 DEGREES
REMARK 500    PHE B  16   CB  -  CG  -  CD2 ANGL. DEV. =   4.9 DEGREES
REMARK 500    PHE B  16   CB  -  CG  -  CD1 ANGL. DEV. =  -4.7 DEGREES
REMARK 500    ARG B  28   NE  -  CZ  -  NH1 ANGL. DEV. =   3.1 DEGREES
REMARK 500    SER B  31   N   -  CA  -  CB  ANGL. DEV. =  11.2 DEGREES
REMARK 500    PHE B  34   N   -  CA  -  CB  ANGL. DEV. =  16.3 DEGREES
REMARK 500    ARG B  37   NE  -  CZ  -  NH1 ANGL. DEV. =   7.6 DEGREES
REMARK 500    PHE B  63   CB  -  CG  -  CD2 ANGL. DEV. =   5.3 DEGREES
REMARK 500    PHE B  67   CB  -  CG  -  CD2 ANGL. DEV. =   4.2 DEGREES
REMARK 500    PHE B  67   CB  -  CG  -  CD1 ANGL. DEV. =  -4.5 DEGREES
REMARK 500    LYS B  73   CA  -  C   -  O   ANGL. DEV. = -58.3 DEGREES
REMARK 500    LYS B  73   O   -  C   -  N   ANGL. DEV. = -56.3 DEGREES
REMARK 500    TYR B  83   CB  -  CG  -  CD2 ANGL. DEV. =  -4.9 DEGREES
REMARK 500    PHE B  87   CB  -  CG  -  CD2 ANGL. DEV. =  -6.0 DEGREES
REMARK 500    PHE B  87   CB  -  CG  -  CD1 ANGL. DEV. =   4.9 DEGREES
REMARK 500    TYR B  89   CA  -  CB  -  CG  ANGL. DEV. = -11.6 DEGREES
REMARK 500    ARG B  93   CB  -  CA  -  C   ANGL. DEV. =  12.3 DEGREES
REMARK 500    ARG B  93   NE  -  CZ  -  NH1 ANGL. DEV. =   4.9 DEGREES
REMARK 500    ARG B 123   NE  -  CZ  -  NH1 ANGL. DEV. =   5.0 DEGREES
REMARK 500    ARG B 123   NE  -  CZ  -  NH2 ANGL. DEV. =  -5.9 DEGREES
REMARK 500    PHE B 126   CB  -  CG  -  CD2 ANGL. DEV. =   4.4 DEGREES
REMARK 500    ARG B 128   NE  -  CZ  -  NH1 ANGL. DEV. =   4.7 DEGREES
REMARK 500    ARG B 128   NE  -  CZ  -  NH2 ANGL. DEV. =  -7.2 DEGREES
REMARK 500    MET B 165   CG  -  SD  -  CE  ANGL. DEV. = -10.5 DEGREES
REMARK 500    ARG B 174   NE  -  CZ  -  NH1 ANGL. DEV. =   4.3 DEGREES
REMARK 500    MET B 179   CG  -  SD  -  CE  ANGL. DEV. = -11.1 DEGREES
REMARK 500    ALA B 182   N   -  CA  -  CB  ANGL. DEV. =   8.4 DEGREES
REMARK 500    TYR B 186   CB  -  CG  -  CD2 ANGL. DEV. =  -6.0 DEGREES
REMARK 500    TYR B 186   CB  -  CG  -  CD1 ANGL. DEV. =   6.0 DEGREES
REMARK 500    ARG B 193   NE  -  CZ  -  NH1 ANGL. DEV. =   3.8 DEGREES
REMARK 500
REMARK 500 THIS ENTRY HAS    1593 ANGLE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500  M RES CSSEQI        PSI       PHI
REMARK 500    ALA A  20     -170.31   -174.70
REMARK 500    LYS A  53      177.18    177.85
REMARK 500    PRO A  60      177.74    -53.51
REMARK 500    VAL A  73     -141.86     80.43
REMARK 500    TYR A  83      136.31   -177.77
REMARK 500    LEU A  98      -29.39    179.45
REMARK 500    LYS A 101       79.53   -110.28
REMARK 500    LEU A 102      144.70   -177.35
REMARK 500    PHE A 133       61.77   -102.77
REMARK 500    PRO A 134       79.77    -21.45
REMARK 500    THR A 150       43.81    144.00
REMARK 500    ALA A 167     -171.82    158.29
REMARK 500    TRP A 197      101.25     41.23
REMARK 500    GLN A 198      101.49     37.89
REMARK 500    ARG B  23      145.10    -31.74
REMARK 500    ARG B  28      135.38    -34.25
REMARK 500    LEU B  32      123.85    -25.61
REMARK 500    PHE B  34      156.23    164.75
REMARK 500    GLU B  36       42.25     74.87
REMARK 500    ASN B  38       94.10     43.91
REMARK 500    ARG B  54       -5.47   -153.57
REMARK 500    PHE B  63      108.64     53.32
REMARK 500    ARG B  64      -12.66   -154.87
REMARK 500    PRO B  66     -168.45   -112.84
REMARK 500    PHE B  67     -123.79    136.40
REMARK 500    ARG B  68       77.36    137.09
REMARK 500    HIS B  71      142.55    -33.93
REMARK 500    LYS B  73      164.87     83.99
REMARK 500    GLU B  74     -110.80   -135.67
REMARK 500    ARG B 123      -12.47     95.10
REMARK 500    ALA B 127       91.23     61.70
REMARK 500    ARG B 128      -49.78   -139.55
REMARK 500    HIS B 139      -86.32   -150.69
REMARK 500    ASN B 140     -175.17     87.48
REMARK 500    ARG B 245        1.57     92.52
REMARK 500    THR B 253      118.58     97.94
REMARK 500    SER E   2        3.77     -4.64
REMARK 500    THR E   3        1.73     -4.48
REMARK 500    GLU E   4      -44.47    -25.57
REMARK 500    LYS E   6      -95.10   -154.83
REMARK 500    GLN E   7       11.98    164.46
REMARK 500    LEU E   8     -154.78     37.67
REMARK 500    ASN E   9     -128.27      5.88
REMARK 500    PRO E  10      -35.35     -7.17
REMARK 500    VAL E  25      -67.52   -146.41
REMARK 500    GLU E  27      154.76    -31.83
REMARK 500    SER E  28      -35.26     76.76
REMARK 500    ARG E  31     -166.10    172.90
REMARK 500    LEU E  32      -72.26    -42.07
REMARK 500    THR E  33       28.58   -166.00
REMARK 500
REMARK 500 THIS ENTRY HAS    1098 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION.  CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS.  TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500                                 MODEL     OMEGA
REMARK 500 MET A    1     SER A    2                 -140.99
REMARK 500 CYS A  163     MET A  164                  149.85
REMARK 500 THR A  208     MET A  209                  145.20
REMARK 500 GLU B   36     ARG B   37                  146.17
REMARK 500 GLY B   39     TYR B   40                  128.44
REMARK 500 TYR B   40     LEU B   41                  145.75
REMARK 500 THR B   62     PHE B   63                   33.21
REMARK 500 ARG B   68     TYR B   69                   32.18
REMARK 500 TYR B   69     LYS B   70                 -141.29
REMARK 500 LYS B   70     HIS B   71                 -142.44
REMARK 500 LEU B  180     LYS B  181                  137.47
REMARK 500 VAL B  225     ARG B  226                 -147.26
REMARK 500 GLY B  244     ARG B  245                  130.05
REMARK 500 LYS E    6     GLN E    7                 -139.90
REMARK 500 GLN E    7     LEU E    8                  143.61
REMARK 500 ASN E    9     PRO E   10                 -139.64
REMARK 500 THR E   55     VAL E   56                  131.36
REMARK 500 ARG E   62     ARG E   63                  144.96
REMARK 500 LYS E   89     GLU E   90                 -147.65
REMARK 500 ASP E  128     PHE E  129                  149.91
REMARK 500 MET F    1     LYS F    2                  121.36
REMARK 500 LYS F    2     THR F    3                   56.35
REMARK 500 ASN F   42     LEU F   43                 -147.71
REMARK 500 SER F  136     GLU F  137                 -148.45
REMARK 500 ASN F  168     LYS F  169                  144.85
REMARK 500 LYS F  169     ASP F  170                  134.60
REMARK 500 THR F  187     GLU F  188                  138.81
REMARK 500 LEU H   63     LYS H   64                  139.79
REMARK 500 ASN H   87     LEU H   88                  -60.84
REMARK 500 LYS H   90     MET H   91                   32.31
REMARK 500 LEU H   93     LYS H   94                  145.96
REMARK 500 LYS H   94     TYR H   95                 -145.52
REMARK 500 TYR H   95     ARG H   96                  136.74
REMARK 500 ARG H   96     PRO H   97                  127.18
REMARK 500 GLU H   98     ASP H   99                  145.93
REMARK 500 ALA H  113     GLU H  114                  147.02
REMARK 500 ALA H  115     GLU H  116                  137.61
REMARK 500 ILE H  126     VAL H  127                  139.41
REMARK 500 ASP H  154     PRO H  155                  -33.06
REMARK 500 GLU H  202     ASP H  203                  144.35
REMARK 500 PHE H  222     ASP H  223                  139.88
REMARK 500 VAL H  233     MET H  234                  -40.19
REMARK 500 ARG H  256     MET H  257                 -132.77
REMARK 500 GLY M    8     SER M    9                  146.74
REMARK 500 MET P    1     GLY P    2                 -149.96
REMARK 500 LYS P   47     ALA P   48                  148.46
REMARK 500 PRO P   74     VAL P   75                  -34.49
REMARK 500 VAL P   80     TYR P   81                   47.68
REMARK 500 GLN P   95     ARG P   96                  141.93
REMARK 500 VAL P  137     ALA P  138                 -149.88
REMARK 500
REMARK 500 THIS ENTRY HAS     499 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: PLANAR GROUPS
REMARK 500
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS
REMARK 500 AN RMSD GREATER THAN THIS VALUE
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500  M RES CSSEQI        RMS     TYPE
REMARK 500    TYR A 204         0.12    SIDE CHAIN
REMARK 500    HIS B  19         0.09    SIDE CHAIN
REMARK 500    ARG B  28         0.09    SIDE CHAIN
REMARK 500    PHE B  29         0.09    SIDE CHAIN
REMARK 500    TYR B  40         0.10    SIDE CHAIN
REMARK 500    ARG B  54         0.08    SIDE CHAIN
REMARK 500    ARG B  64         0.08    SIDE CHAIN
REMARK 500    TYR B  69         0.15    SIDE CHAIN
REMARK 500    ARG B  93         0.16    SIDE CHAIN
REMARK 500    ARG B 128         0.18    SIDE CHAIN
REMARK 500    TYR B 189         0.09    SIDE CHAIN
REMARK 500    ARG B 190         0.10    SIDE CHAIN
REMARK 500    ARG B 226         0.19    SIDE CHAIN
REMARK 500    ARG E  31         0.10    SIDE CHAIN
REMARK 500    ARG E  62         0.26    SIDE CHAIN
REMARK 500    ARG E  74         0.24    SIDE CHAIN
REMARK 500    ARG E  96         0.31    SIDE CHAIN
REMARK 500    TYR E 118         0.10    SIDE CHAIN
REMARK 500    ARG E 142         0.09    SIDE CHAIN
REMARK 500    ARG E 143         0.09    SIDE CHAIN
REMARK 500    ARG E 144         0.25    SIDE CHAIN
REMARK 500    ARG E 155         0.14    SIDE CHAIN
REMARK 500    ARG F  31         0.15    SIDE CHAIN
REMARK 500    ARG F  36         0.10    SIDE CHAIN
REMARK 500    ARG F  70         0.17    SIDE CHAIN
REMARK 500    TYR F  95         0.13    SIDE CHAIN
REMARK 500    ARG F 123         0.10    SIDE CHAIN
REMARK 500    ARG F 172         0.12    SIDE CHAIN
REMARK 500    ARG H  60         0.15    SIDE CHAIN
REMARK 500    ARG H  66         0.12    SIDE CHAIN
REMARK 500    PHE H  76         0.11    SIDE CHAIN
REMARK 500    ARG H  96         0.10    SIDE CHAIN
REMARK 500    ARG H 106         0.08    SIDE CHAIN
REMARK 500    ARG H 110         0.07    SIDE CHAIN
REMARK 500    TYR H 130         0.13    SIDE CHAIN
REMARK 500    HIS H 134         0.09    SIDE CHAIN
REMARK 500    TYR H 137         0.05    SIDE CHAIN
REMARK 500    TYR M  38         0.10    SIDE CHAIN
REMARK 500    ARG M  73         0.20    SIDE CHAIN
REMARK 500    ARG M  89         0.18    SIDE CHAIN
REMARK 500    TYR P   6         0.09    SIDE CHAIN
REMARK 500    ARG P  12         0.09    SIDE CHAIN
REMARK 500    ARG P  13         0.10    SIDE CHAIN
REMARK 500    ARG P  20         0.11    SIDE CHAIN
REMARK 500    ARG P  24         0.15    SIDE CHAIN
REMARK 500    ARG P  26         0.08    SIDE CHAIN
REMARK 500    TYR P  30         0.12    SIDE CHAIN
REMARK 500    ARG P  31         0.09    SIDE CHAIN
REMARK 500    ARG P  41         0.13    SIDE CHAIN
REMARK 500    ARG P  50         0.13    SIDE CHAIN
REMARK 500
REMARK 500 THIS ENTRY HAS     356 PLANE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: MAIN CHAIN PLANARITY
REMARK 500
REMARK 500 THE FOLLOWING RESIDUES HAVE A PSEUDO PLANARITY
REMARK 500 TORSION ANGLE, C(I) - CA(I) - N(I+1) - O(I), GREATER
REMARK 500 10.0 DEGREES. (M=MODEL NUMBER; RES=RESIDUE NAME;
REMARK 500 C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 500 I=INSERTION CODE).
REMARK 500
REMARK 500  M RES CSSEQI        ANGLE
REMARK 500    ASP B  33        -13.74
REMARK 500    LYS B  73        127.98
REMARK 500    TRP B 196        116.92
REMARK 500    VAL E  88         19.41
REMARK 500    ALA E 136        -12.00
REMARK 500    LYS F   2       -130.76
REMARK 500    THR F 187        -44.20
REMARK 500    ASN H  87        122.07
REMARK 500    PRO H  97         43.37
REMARK 500    VAL H 233        128.24
REMARK 500    ASP M  71         10.46
REMARK 500    PRO P  74        106.78
REMARK 500    HIS O  40       -123.34
REMARK 500    LYS O 127       -130.28
REMARK 500    GLY O 137         65.50
REMARK 500    ALA R  97        -57.47
REMARK 500    TYR Q  16        -92.27
REMARK 500    THR Q 112        119.53
REMARK 500    LEU Q 116         60.18
REMARK 500    VAL Q 124        103.72
REMARK 500    ASP Q 137        113.97
REMARK 500    GLY Q 235        124.13
REMARK 500    GLU Q 237        119.09
REMARK 500    SER Q 238        128.51
REMARK 500    ALA Q 249       -126.17
REMARK 500    SER Q 256        -12.75
REMARK 500    THR Q 257        -13.92
REMARK 500    SER Q 290        123.61
REMARK 500    GLN T  71        129.60
REMARK 500    PRO T  90         12.11
REMARK 500    ARG T 136        -33.92
REMARK 500    ILE U 126        122.81
REMARK 500    GLY U 138        -59.38
REMARK 500    MET U 140         55.33
REMARK 500    ILE V  36        115.83
REMARK 500    ARG V  69       -126.89
REMARK 500    ILE V 166         55.44
REMARK 500    LYS V 170       -128.48
REMARK 500    SER X  33         46.12
REMARK 500    TRP Z  53       -124.89
REMARK 500    SER Y   9       -123.60
REMARK 500    LYS Y 109         10.25
REMARK 500    LYS h  13        127.02
REMARK 500    ARG l  11         50.07
REMARK 500    VAL n  47       -129.29
REMARK 500    ARG o  30         58.96
REMARK 500    LYS r  32        -61.32
REMARK 500    LYS r  46        -10.28
REMARK 500    LYS r  61         53.82
REMARK 500    LYS r  89        131.13
REMARK 500
REMARK 500 THIS ENTRY HAS     142 MAIN CHAIN PLANARITY DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CHIRAL CENTERS
REMARK 500
REMARK 500 UNEXPECTED CONFIGURATION OF THE FOLLOWING CHIRAL
REMARK 500 CENTER(S) USING IMPROPER CA--C--CB--N CHIRALITY
REMARK 500 FOR AMINO ACIDS AND C1'--O4'--N1(N9)--C2' FOR
REMARK 500 NUCLEIC ACIDS OR EQUIVALENT ANGLE
REMARK 500 M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,6X,F5.1,6X,A1,10X,A1,3X,A16)
REMARK 500
REMARK 500  M RES CSSEQI    IMPROPER   EXPECTED   FOUND DETAILS
REMARK 500    GLU A  19        24.4      L          L   OUTSIDE RANGE
REMARK 500    LYS A  24        22.6      L          L   OUTSIDE RANGE
REMARK 500    ARG A 121        16.4      L          L   OUTSIDE RANGE
REMARK 500    GLN A 157        23.2      L          L   OUTSIDE RANGE
REMARK 500    LYS A 160        18.7      L          L   OUTSIDE RANGE
REMARK 500    TRP A 197        23.8      L          L   OUTSIDE RANGE
REMARK 500    HIS B  22        24.6      L          L   OUTSIDE RANGE
REMARK 500    LYS B  24        22.9      L          L   OUTSIDE RANGE
REMARK 500    ARG B  28        24.5      L          L   OUTSIDE RANGE
REMARK 500    GLU B  36        21.1      L          L   OUTSIDE RANGE
REMARK 500    HIS B  65        22.9      L          L   OUTSIDE RANGE
REMARK 500    LYS B  73        24.5      L          L   OUTSIDE RANGE
REMARK 500    THR B  84        21.7      L          L   OUTSIDE RANGE
REMARK 500    ARG B  93        16.5      L          L   OUTSIDE RANGE
REMARK 500    ALA B 127        24.2      L          L   OUTSIDE RANGE
REMARK 500    TRP B 196        47.0      L          L   OUTSIDE RANGE
REMARK 500    MET E   1       -29.2      L          D   WRONG HAND
REMARK 500    SER E   2        23.4      L          L   OUTSIDE RANGE
REMARK 500    LEU E   8        22.4      L          L   OUTSIDE RANGE
REMARK 500    ASN E   9         8.9      L          L   EXPECTING SP3
REMARK 500    PRO E  10        24.5      L          L   OUTSIDE RANGE
REMARK 500    ARG E  34        20.9      L          L   OUTSIDE RANGE
REMARK 500    ARG E  63        19.1      L          L   OUTSIDE RANGE
REMARK 500    LEU E  86        23.1      L          L   OUTSIDE RANGE
REMARK 500    VAL E  88        21.3      L          L   OUTSIDE RANGE
REMARK 500    TYR E 118        21.6      L          L   OUTSIDE RANGE
REMARK 500    ILE E 124        23.7      L          L   OUTSIDE RANGE
REMARK 500    TYR E 169        21.2      L          L   OUTSIDE RANGE
REMARK 500    LYS F  39        24.4      L          L   OUTSIDE RANGE
REMARK 500    LYS F 120        23.8      L          L   OUTSIDE RANGE
REMARK 500    SER F 154        24.8      L          L   OUTSIDE RANGE
REMARK 500    ASP F 170        24.1      L          L   OUTSIDE RANGE
REMARK 500    THR F 187        45.4      L          L   OUTSIDE RANGE
REMARK 500    ARG H  60        16.9      L          L   OUTSIDE RANGE
REMARK 500    ILE H  62        15.1      L          L   OUTSIDE RANGE
REMARK 500    LEU H  63        22.7      L          L   OUTSIDE RANGE
REMARK 500    THR H  86        20.8      L          L   OUTSIDE RANGE
REMARK 500    LYS H  94        24.9      L          L   OUTSIDE RANGE
REMARK 500    GLU H  98        21.5      L          L   OUTSIDE RANGE
REMARK 500    ILE H 126        24.1      L          L   OUTSIDE RANGE
REMARK 500    LEU H 162        24.2      L          L   OUTSIDE RANGE
REMARK 500    GLU H 170        24.5      L          L   OUTSIDE RANGE
REMARK 500    GLU H 202        23.0      L          L   OUTSIDE RANGE
REMARK 500    LYS H 215        24.7      L          L   OUTSIDE RANGE
REMARK 500    TRP H 229        22.5      L          L   OUTSIDE RANGE
REMARK 500    ARG M  51        24.4      L          L   OUTSIDE RANGE
REMARK 500    LYS M  69         8.1      L          L   EXPECTING SP3
REMARK 500    LEU M  72        16.2      L          L   OUTSIDE RANGE
REMARK 500    MET P   1        23.8      L          L   OUTSIDE RANGE
REMARK 500    ASP P  17        22.6      L          L   OUTSIDE RANGE
REMARK 500
REMARK 500 THIS ENTRY HAS     493 CHIRALITY DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-1780   RELATED DB: EMDB
REMARK 999
REMARK 999 SEQUENCE
REMARK 999 THE CRYO-EM MAP WAS OBTAINED FROM T. AESTIVUM. SOME OF THE CHAINS
REMARK 999 WERE MODELED USING THE HOMOLOGS FROM OTHER ORGANISMS.
DBREF  3IZR A    1   216  UNP    Q5I7L3   Q5I7L3_WHEAT     1    216
DBREF  3IZR B    1   261  UNP    Q2QNF3   Q2QNF3_ORYSJ     1    261
DBREF  3IZR E    1   180  UNP    Q5I7L2   Q5I7L2_WHEAT     1    180
DBREF  3IZR F    1   190  UNP    P49210   RL9_ORYSJ        1    190
DBREF  3IZR H    1   258  UNP    P35685   RL7A_ORYSJ       1    258
DBREF  3IZR I    1   224  UNP    Q0ITS8   RL101_ORYSJ      1    224
DBREF  3IZR M    1   140  UNP    Q5I7K4   Q5I7K4_WHEAT     1    140
DBREF  3IZR P    1   204  UNP    Q8H8S1   Q8H8S1_ORYSJ     1    204
DBREF  3IZR O    1   144  UNP    Q6EUQ7   Q6EUQ7_ORYSJ     1    144
DBREF  3IZR R    1   188  UNP    Q5I7L0   Q5I7L0_WHEAT     1    188
DBREF  3IZR Q    1   304  UNP    Q8L4L4   RL52_ORYSJ       1    304
DBREF  3IZR T    1   209  UNP    Q7XY20   Q7XY20_WHEAT     1    209
DBREF  3IZR U    1   164  UNP    Q7XYC9   Q7XYC9_WHEAT     9    172
DBREF  3IZR V    1   171  UNP    Q6K1W6   Q6K1W6_ORYSJ     1    171
DBREF  3IZR X    1   152  UNP    Q94CM9   Q94CM9_ORYSJ     1    152
DBREF  3IZR Z    1   162  UNP    Q5N754   Q5N754_ORYSJ     1    162
DBREF  3IZR Y    1   150  UNP    Q2QXN5   Q2QXN5_ORYSJ     1    150
DBREF  3IZR b    2   148  UNP    Q5TKP3   Q5TKP3_ORYSJ     1    147
DBREF  3IZR d    1    60  UNP    Q9FP55   Q9FP55_ORYSJ     1     60
DBREF  3IZR f    1   112  UNP    Q5I7K9   RL30_WHEAT       1    112
DBREF  3IZR g    1   123  UNP    Q6ZGV5   Q6ZGV5_ORYSJ     1    123
DBREF  3IZR h    1   133  UNP    Q3MST7   Q3MST7_ORYSI     1    133
DBREF  3IZR l    1    94  UNP    Q6Z8Y5   Q6Z8Y5_ORYSJ     1     94
DBREF  3IZR n    1    69  UNP    Q8GVY2   Q8GVY2_ORYSJ     1     69
DBREF  3IZR o    1    51  UNP    Q5I7K7   Q5I7K7_WHEAT     1     51
DBREF  3IZR r    1   105  UNP    Q8H5N0   Q8H5N0_ORYSJ     1    105
DBREF  3IZR q    1    25  UNP    Q8GVZ2   Q8GVZ2_ORYSJ    61     85
DBREF  3IZR G    1   219  UNP    Q5I7L4   Q5I7L4_WHEAT     1    219
DBREF  3IZR N    1   134  UNP    Q6K1Q6   Q6K1Q6_ORYSJ     1    134
DBREF  3IZR S    1   178  UNP    Q0JJA0   Q0JJA0_ORYSJ     1    178
DBREF  3IZR W    1   130  UNP    Q6YSX0   Q6YSX0_ORYSJ     1    130
DBREF  3IZR a    1   136  UNP    Q7XC31   Q7XC31_ORYSJ     1    136
DBREF  3IZR i    1   119  UNP    Q5I7K8   Q5I7K8_WHEAT     1    119
DBREF  3IZR j    1   111  UNP    Q6I608   Q6I608_ORYSJ     1    111
DBREF  3IZR k    1   112  UNP    Q5I7L5   Q5I7L5_WHEAT     1    112
DBREF  3IZR p    1    53  UNP    Q10PH1   Q10PH1_ORYSJ    77    129
DBREF  3IZR J    1   166  UNP    Q0JAI2   Q0JAI2_ORYSJ     1    166
DBREF  3IZR t    1   110  UNP    Q5I7K5   Q5I7K5_WHEAT     1    110
DBREF  3IZR u    1   110  UNP    Q5I7K5   Q5I7K5_WHEAT     1    110
DBREF  3IZR v    2   113  UNP    Q7X729   Q7X729_WHEAT     1    112
DBREF  3IZR w    2   113  UNP    Q7X729   Q7X729_WHEAT     1    112
DBREF  3IZR c    1   124  UNP    Q8L805   RL35_WHEAT       1    124
DBREF  3IZR e    1   244  UNP    Q5I7K6   Q5I7K6_WHEAT     1    244
DBREF  3IZR s    1   319  UNP    P41095   RLA0_ORYSJ       1    319
DBREF  3IZR C    1   389  UNP    Q7X744   Q7X744_WHEAT     1    389
DBREF  3IZR D    1   405  UNP    Q6ZLB8   Q6ZLB8_ORYSJ     1    405
DBREF  3IZR K    1   206  UNP    Q5I7L1   Q5I7L1_WHEAT     1    206
DBREF  3IZR m    1    92  UNP    Q5QM99   RL37A_ORYSJ      1     92
DBREF  3IZR L   12   194  PDB    3IZR     3IZR            12    194
DBREF  3IZR y    1    20  PDB    3IZR     3IZR             1     20
DBREF  3IZR x    1    20  PDB    3IZR     3IZR             1     20
DBREF  3IZR z    1    14  PDB    3IZR     3IZR             1     14
SEQADV 3IZR MET v    1  UNP  Q7X729              EXPRESSION TAG
SEQADV 3IZR MET w    1  UNP  Q7X729              EXPRESSION TAG
SEQRES   1 A  216  MET SER LYS LEU GLN SER ASP ALA VAL LYS ASP ALA ILE
SEQRES   2 A  216  THR GLN ILE VAL GLY GLU ALA ARG GLU LYS LYS ARG LYS
SEQRES   3 A  216  PHE THR GLU THR VAL GLU LEU GLN ILE GLY LEU LYS ASN
SEQRES   4 A  216  TYR ASP PRO GLN LYS ASP LYS ARG PHE SER GLY SER VAL
SEQRES   5 A  216  LYS LEU PRO HIS ILE PRO ARG PRO LYS MET ARG VAL CYS
SEQRES   6 A  216  MET LEU GLY ASP ALA GLN HIS VAL ASP GLN ALA GLU LYS
SEQRES   7 A  216  MET GLY LEU ASP TYR MET ASP VAL GLU SER LEU LYS LYS
SEQRES   8 A  216  MET ASN LYS ASN LYS LYS LEU VAL LYS LYS LEU ALA LYS
SEQRES   9 A  216  LYS TYR HIS ALA PHE LEU ALA SER GLU ALA ILE ILE LYS
SEQRES  10 A  216  GLN ILE PRO ARG LEU LEU GLY PRO GLY LEU ASN LYS ALA
SEQRES  11 A  216  GLY LYS PHE PRO THR LEU VAL SER HIS GLN GLU SER LEU
SEQRES  12 A  216  GLU ALA LYS VAL ASN GLU THR LYS ALA THR VAL LYS PHE
SEQRES  13 A  216  GLN LEU LYS LYS VAL LEU CYS MET GLY VAL ALA VAL GLY
SEQRES  14 A  216  ASN LEU SER MET ASP GLU LYS GLN ILE GLN GLN ASN ILE
SEQRES  15 A  216  GLN MET SER VAL ASN PHE LEU VAL SER LEU LEU LYS LYS
SEQRES  16 A  216  ASN TRP GLN ASN VAL ARG CYS LEU TYR VAL LYS SER THR
SEQRES  17 A  216  MET GLY LYS ARG VAL ARG VAL PHE
SEQRES   1 B  261  MET GLY ARG VAL ILE ARG ALA GLN ARG LYS GLY ALA GLY
SEQRES   2 B  261  SER VAL PHE LYS SER HIS THR HIS HIS ARG LYS GLY PRO
SEQRES   3 B  261  ALA ARG PHE ARG SER LEU ASP PHE GLY GLU ARG ASN GLY
SEQRES   4 B  261  TYR LEU LYS GLY VAL VAL THR ASP ILE ILE HIS ASP PRO
SEQRES   5 B  261  GLY ARG GLY ALA PRO LEU ALA LYS VAL THR PHE ARG HIS
SEQRES   6 B  261  PRO PHE ARG TYR LYS HIS GLN LYS GLU LEU PHE VAL ALA
SEQRES   7 B  261  ALA GLU GLY MET TYR THR GLY GLN PHE VAL TYR CYS GLY
SEQRES   8 B  261  ARG ARG ALA THR LEU SER ILE GLY ASN VAL LEU PRO ILE
SEQRES   9 B  261  ARG SER VAL PRO GLU GLY ALA VAL VAL CYS ASN VAL GLU
SEQRES  10 B  261  HIS HIS VAL GLY ASP ARG GLY VAL PHE ALA ARG ALA SER
SEQRES  11 B  261  GLY ASP TYR ALA ILE VAL ILE SER HIS ASN PRO ASP ASN
SEQRES  12 B  261  GLY THR SER ARG ILE LYS LEU PRO SER GLY ALA LYS LYS
SEQRES  13 B  261  ILE VAL PRO SER SER CYS ARG ALA MET ILE GLY GLN VAL
SEQRES  14 B  261  ALA GLY GLY GLY ARG THR GLU LYS PRO MET LEU LYS ALA
SEQRES  15 B  261  GLY ASN ALA TYR HIS LYS TYR ARG VAL LYS ARG ASN CYS
SEQRES  16 B  261  TRP PRO LYS VAL ARG GLY VAL ALA MET ASN PRO VAL GLU
SEQRES  17 B  261  HIS PRO HIS GLY GLY GLY ASN HIS GLN HIS ILE GLY HIS
SEQRES  18 B  261  ALA SER THR VAL ARG ARG ASP ALA PRO PRO GLY GLN LYS
SEQRES  19 B  261  VAL GLY LEU ILE ALA ALA ARG ARG THR GLY ARG LEU ARG
SEQRES  20 B  261  GLY GLN ALA ALA ALA THR ALA ALA LYS ALA ASP LYS ALA
SEQRES  21 B  261  THR
SEQRES   1 E  180  MET SER THR GLU LYS LYS GLN LEU ASN PRO MET ARG ASP
SEQRES   2 E  180  ILE LYS VAL GLN LYS LEU VAL LEU ASN ILE SER VAL GLY
SEQRES   3 E  180  GLU SER GLY ASP ARG LEU THR ARG ALA SER LYS VAL LEU
SEQRES   4 E  180  GLU GLN LEU SER GLY GLN SER PRO VAL PHE SER LYS ALA
SEQRES   5 E  180  ARG TYR THR VAL ARG SER PHE GLY ILE ARG ARG ASN GLU
SEQRES   6 E  180  LYS ILE ALA CYS TYR VAL THR ILE ARG GLY GLU LYS ALA
SEQRES   7 E  180  MET GLN LEU LEU GLU SER GLY LEU LYS VAL LYS GLU TYR
SEQRES   8 E  180  GLU LEU LEU ARG ARG ASN PHE SER ASP THR GLY CYS PHE
SEQRES   9 E  180  GLY PHE GLY ILE GLN GLU HIS ILE ASP LEU GLY MET LYS
SEQRES  10 E  180  TYR ASP PRO SER THR GLY ILE TYR GLY MET ASP PHE PHE
SEQRES  11 E  180  VAL VAL LEU GLU ARG ALA GLY TYR ARG VAL SER ARG ARG
SEQRES  12 E  180  ARG ARG CYS LYS ALA ARG VAL GLY ILE HIS GLN ARG VAL
SEQRES  13 E  180  THR LYS GLU ASP ALA MET LYS TRP PHE GLN VAL LYS TYR
SEQRES  14 E  180  GLU GLY VAL ILE LEU ASN LYS SER HIS ALA SER
SEQRES   1 F  190  MET LYS THR ILE LEU ALA SER GLU THR MET GLU ILE PRO
SEQRES   2 F  190  GLU GLY VAL THR VAL GLN VAL ALA ALA LYS VAL VAL THR
SEQRES   3 F  190  VAL GLU GLY PRO ARG GLY LYS LEU THR ARG ASN PHE LYS
SEQRES   4 F  190  HIS LEU ASN LEU ASP PHE GLN LEU LEU GLU GLY GLY ARG
SEQRES   5 F  190  LYS LEU GLN VAL ASP ALA TRP PHE GLY THR ARG ARG THR
SEQRES   6 F  190  MET ALA ALA ILE ARG THR ALA ILE SER HIS VAL GLN ASN
SEQRES   7 F  190  LEU ILE THR GLY VAL THR LYS GLY TYR ARG TYR LYS MET
SEQRES   8 F  190  ARG PHE VAL TYR ALA HIS PHE PRO ILE ASN ALA SER ILE
SEQRES   9 F  190  THR ASN SER ASN THR ALA ILE GLU ILE ARG ASN PHE LEU
SEQRES  10 F  190  GLY GLU LYS LYS VAL ARG LYS VAL ASP MET LEU GLU GLY
SEQRES  11 F  190  VAL THR ILE LEU ARG SER GLU LYS VAL LYS ASP GLU LEU
SEQRES  12 F  190  VAL LEU ASP GLY ASN ASP ILE GLU LEU VAL SER ARG SER
SEQRES  13 F  190  ALA ALA LEU ILE ASN GLN LYS CYS HIS VAL LYS ASN LYS
SEQRES  14 F  190  ASP ILE ARG LYS PHE LEU ASP GLY ILE TYR VAL SER ASP
SEQRES  15 F  190  LYS GLY THR ILE THR GLU ASP ALA
SEQRES   1 H  258  MET ALA PRO LYS ARG GLY GLY ARG ALA PRO VAL PRO ALA
SEQRES   2 H  258  LYS LYS LYS THR GLU LYS VAL THR ASN PRO LEU PHE GLU
SEQRES   3 H  258  LYS ARG PRO LYS GLN PHE GLY ILE GLY GLY ALA LEU PRO
SEQRES   4 H  258  PRO LYS LYS ASP LEU HIS ARG PHE VAL LYS TRP PRO LYS
SEQRES   5 H  258  VAL VAL ARG ILE GLN ARG GLN ARG ARG ILE LEU LYS GLN
SEQRES   6 H  258  ARG LEU LYS VAL PRO PRO ALA LEU ASN GLN PHE THR ARG
SEQRES   7 H  258  THR LEU ASP LYS ASN LEU ALA THR ASN LEU PHE LYS MET
SEQRES   8 H  258  LEU LEU LYS TYR ARG PRO GLU ASP LYS ALA ALA LYS LYS
SEQRES   9 H  258  GLU ARG LEU LEU LYS ARG ALA GLN ALA GLU ALA GLU GLY
SEQRES  10 H  258  LYS THR VAL GLU ALA LYS LYS PRO ILE VAL VAL LYS TYR
SEQRES  11 H  258  GLY LEU ASN HIS VAL THR TYR LEU ILE GLU GLN SER LYS
SEQRES  12 H  258  ALA GLN LEU VAL VAL ILE ALA HIS ASP VAL ASP PRO ILE
SEQRES  13 H  258  GLU LEU VAL VAL TRP LEU PRO ALA LEU CYS ARG LYS MET
SEQRES  14 H  258  GLU VAL PRO TYR CYS ILE VAL LYS GLY LYS ALA ARG LEU
SEQRES  15 H  258  GLY SER ILE VAL HIS LYS LYS THR ALA SER VAL LEU CYS
SEQRES  16 H  258  LEU THR THR VAL LYS ASN GLU ASP LYS LEU GLU PHE SER
SEQRES  17 H  258  LYS ILE LEU GLU ALA ILE LYS ALA ASN PHE ASN ASP LYS
SEQRES  18 H  258  PHE ASP GLU VAL ARG LYS LYS TRP GLY GLY GLY VAL MET
SEQRES  19 H  258  GLY SER LYS SER GLN ALA LYS THR LYS ALA ARG GLU LYS
SEQRES  20 H  258  LEU LEU ALA LYS GLU ALA ALA GLN ARG MET THR
SEQRES   1 M  140  MET SER LYS ARG GLY ARG GLY GLY SER ALA GLY ASN LYS
SEQRES   2 M  140  PHE ARG MET SER LEU GLY LEU PRO VAL ALA ALA THR VAL
SEQRES   3 M  140  ASN CYS ALA ASP ASN THR GLY ALA LYS ASN LEU TYR ILE
SEQRES   4 M  140  ILE SER VAL LYS GLY ILE LYS GLY ARG LEU ASN ARG LEU
SEQRES   5 M  140  PRO SER ALA CYS VAL GLY ASP MET VAL MET ALA THR VAL
SEQRES   6 M  140  LYS LYS GLY LYS PRO ASP LEU ARG LYS LYS VAL MET PRO
SEQRES   7 M  140  ALA VAL ILE VAL ARG GLN ARG LYS PRO TRP ARG ARG LYS
SEQRES   8 M  140  ASP GLY VAL PHE MET TYR PHE GLU ASP ASN ALA GLY VAL
SEQRES   9 M  140  ILE VAL ASN PRO LYS GLY GLU MET LYS GLY SER ALA ILE
SEQRES  10 M  140  THR GLY PRO ILE GLY LYS GLU CYS ALA ASP LEU TRP PRO
SEQRES  11 M  140  ARG ILE ALA SER ALA ALA ASN ALA ILE VAL
SEQRES   1 P  204  MET GLY ALA TYR LYS TYR VAL SER GLU LEU TRP ARG ARG
SEQRES   2 P  204  LYS GLN SER ASP VAL MET ARG PHE VAL GLN ARG VAL ARG
SEQRES   3 P  204  CYS TRP GLU TYR ARG GLN GLN PRO ALA ILE VAL ARG LEU
SEQRES   4 P  204  THR ARG PRO THR ARG PRO ASP LYS ALA ARG ARG LEU GLY
SEQRES   5 P  204  TYR LYS ALA LYS GLN GLY TYR VAL VAL TYR ARG VAL ARG
SEQRES   6 P  204  VAL ARG ARG GLY GLY ARG LYS ARG PRO VAL PRO LYS GLY
SEQRES   7 P  204  ILE VAL TYR GLY LYS PRO LYS HIS GLN GLY ILE THR GLN
SEQRES   8 P  204  LEU LYS PHE GLN ARG ASN LYS ARG SER VAL ALA GLU GLU
SEQRES   9 P  204  ARG ALA GLY ARG LYS LEU GLY GLY LEU ARG VAL LEU ASN
SEQRES  10 P  204  SER TYR TRP VAL ASN GLU ASP SER THR TYR LYS TYR PHE
SEQRES  11 P  204  GLU ILE ILE LEU VAL ASP VAL ALA HIS SER ALA ILE ARG
SEQRES  12 P  204  ASN ASP PRO ARG ILE ASN TRP LEU CYS LYS PRO VAL HIS
SEQRES  13 P  204  LYS HIS ARG GLU LEU ARG GLY LEU THR SER ALA GLY LYS
SEQRES  14 P  204  LYS TYR ARG GLY LEU ARG GLY LYS GLY HIS THR HIS HIS
SEQRES  15 P  204  LYS ALA ARG PRO SER ARG ARG ALA THR TRP LYS ARG ASN
SEQRES  16 P  204  GLN THR VAL SER LEU ARG ARG TYR ARG
SEQRES   1 O  144  MET THR THR ARG PHE LYS LYS ASN ARG LYS LYS ARG GLY
SEQRES   2 O  144  HIS VAL SER ALA GLY HIS GLY ARG ILE GLY LYS HIS ARG
SEQRES   3 O  144  LYS HIS PRO GLY GLY ARG GLY ASN ALA GLY GLY MET HIS
SEQRES   4 O  144  HIS HIS ARG ILE LEU PHE ASP LYS TYR HIS PRO GLY TYR
SEQRES   5 O  144  PHE GLY LYS VAL GLY MET ARG TYR PHE HIS ARG LEU SER
SEQRES   6 O  144  ASN ARG PHE HIS CYS PRO ALA VAL ASN VAL GLU ARG LEU
SEQRES   7 O  144  TRP SER MET VAL PRO ALA GLU ALA GLY ALA GLY ALA GLY
SEQRES   8 O  144  LYS ALA PRO VAL ILE ASP VAL THR GLN PHE GLY TYR THR
SEQRES   9 O  144  LYS VAL LEU GLY LYS GLY MET LEU PRO PRO GLU ARG PRO
SEQRES  10 O  144  ILE VAL VAL LYS ALA LYS LEU ILE SER LYS VAL ALA GLU
SEQRES  11 O  144  LYS LYS ILE LYS ALA ALA GLY GLY ALA VAL LEU LEU THR
SEQRES  12 O  144  ALA
SEQRES   1 R  188  MET GLY ILE ASP LEU VAL ALA GLY GLY ARG ASN LYS ARG
SEQRES   2 R  188  THR LYS ARG VAL ALA PRO LYS SER ASP ASP VAL TYR LEU
SEQRES   3 R  188  LYS LEU LEU VAL LYS LEU TYR ARG PHE LEU VAL ARG ARG
SEQRES   4 R  188  THR LYS SER LYS PHE ASN ALA VAL ILE LEU LYS ARG LEU
SEQRES   5 R  188  PHE MET SER LYS THR ASN ARG PRO PRO LEU SER MET ARG
SEQRES   6 R  188  ARG LEU SER ASN PHE MET LYS GLY LYS GLU GLU LYS ASN
SEQRES   7 R  188  ILE ALA VAL VAL VAL GLY THR ILE THR ASP ASP MET ARG
SEQRES   8 R  188  ILE GLN GLU VAL PRO ALA MET LYS VAL THR ALA LEU ARG
SEQRES   9 R  188  PHE THR GLU THR ALA ARG ALA ARG ILE ILE ASN ALA GLY
SEQRES  10 R  188  GLY GLU CYS LEU THR PHE ASP GLN LEU ALA LEU ARG ALA
SEQRES  11 R  188  PRO THR GLY GLU ASN THR ILE LEU LEU ARG GLY PRO LYS
SEQRES  12 R  188  ASN ALA ARG GLU ALA VAL ARG HIS PHE GLY LYS ALA PRO
SEQRES  13 R  188  GLY VAL PRO HIS SER HIS THR LYS PRO TYR VAL ARG SER
SEQRES  14 R  188  LYS GLY ARG LYS PHE GLU LYS VAL ARG GLY ARG ARG ASN
SEQRES  15 R  188  SER ARG GLY PHE LYS VAL
SEQRES   1 Q  304  MET SER LEU GLN GLY GLY PHE VAL LYS THR GLN LYS THR
SEQRES   2 Q  304  HIS ALA TYR PHE LYS ARG PHE GLN VAL LYS PHE LYS ARG
SEQRES   3 Q  304  ARG ARG GLN GLY LYS THR ASP TYR ARG ALA ARG ILE ARG
SEQRES   4 Q  304  LEU THR ASN GLN ASP LYS ASN LYS TYR ASN THR PRO LYS
SEQRES   5 Q  304  TYR ARG PHE VAL THR ASN LYS ASP ILE THR ALA GLN ILE
SEQRES   6 Q  304  VAL TYR ALA THR ILE ALA GLY ASP ILE VAL MET ALA ALA
SEQRES   7 Q  304  ALA TYR SER HIS GLU LEU PRO ARG TYR GLY LEU GLU VAL
SEQRES   8 Q  304  GLY LEU THR ASN TYR ALA ALA ALA TYR CYS THR GLY LEU
SEQRES   9 Q  304  LEU LEU ALA ARG ARG VAL LEU THR LEU ARG GLY LEU ASP
SEQRES  10 Q  304  GLN GLU TYR GLU GLY ASN VAL GLU ALA THR GLY GLU ASP
SEQRES  11 Q  304  TYR TYR VAL GLU PRO ALA ASP GLU ARG ARG PRO PHE ARG
SEQRES  12 Q  304  ALA LEU LEU ASP VAL GLY LEU ILE ARG THR THR THR GLY
SEQRES  13 Q  304  ASN ARG VAL PHE GLY ALA LEU LYS GLY ALA LEU ASP GLY
SEQRES  14 Q  304  GLY LEU ASP ILE PRO HIS SER ASP LYS ARG PHE ALA GLY
SEQRES  15 Q  304  PHE LYS LYS ASP GLU LYS GLN LEU ASP SER ASP ILE HIS
SEQRES  16 Q  304  ARG LYS TYR ILE TYR GLY GLY HIS VAL ALA ASP TYR MET
SEQRES  17 Q  304  ARG SER MET ALA GLU GLU GLU PRO GLU LYS PHE GLN ALA
SEQRES  18 Q  304  HIS PHE SER GLU TYR LEU LYS LYS GLY ILE ASP ALA ASP
SEQRES  19 Q  304  GLY MET GLU SER LEU TYR LYS LYS VAL HIS ALA ALA ILE
SEQRES  20 Q  304  ARG ALA ASP PRO THR MET ALA LYS SER THR LYS LYS GLU
SEQRES  21 Q  304  PRO ALA THR HIS LYS ARG TYR ASN LEU LYS LYS LEU THR
SEQRES  22 Q  304  TYR GLU GLN ARG LYS ALA SER LEU VAL GLU ARG LEU ASN
SEQRES  23 Q  304  ALA LEU ASN SER SER ALA GLY ALA ASP ASP ASP ASP GLU
SEQRES  24 Q  304  GLU GLU ASP ASP GLU
SEQRES   1 T  209  MET VAL SER LEU LYS LEU GLN LYS ARG LEU ALA SER SER
SEQRES   2 T  209  VAL LEU LYS CYS GLY LYS GLY LYS VAL TRP LEU ASP PRO
SEQRES   3 T  209  ASN GLU VAL ASN GLU ILE SER MET ALA ASN SER ARG GLN
SEQRES   4 T  209  ASN ILE ARG LYS LEU VAL LYS ASP GLY PHE ILE ILE ARG
SEQRES   5 T  209  LYS PRO GLN LYS ILE HIS SER ARG SER ARG ALA ARG ARG
SEQRES   6 T  209  ALA HIS GLU ALA LYS GLN LYS GLY ARG HIS SER GLY TYR
SEQRES   7 T  209  GLY LYS ARG ARG GLY THR ARG GLU ALA ARG LEU PRO THR
SEQRES   8 T  209  LYS ILE LEU TRP MET ARG ARG MET ARG VAL LEU ARG ARG
SEQRES   9 T  209  LEU LEU ARG LYS TYR ARG GLU ALA LYS LYS ILE ASP LYS
SEQRES  10 T  209  HIS MET TYR HIS ASP MET TYR LEU LYS VAL LYS GLY ASN
SEQRES  11 T  209  MET PHE LYS ASN LYS ARG VAL LEU MET GLU SER ILE HIS
SEQRES  12 T  209  LYS SER LYS ALA GLU LYS ALA ARG GLU LYS THR LEU SER
SEQRES  13 T  209  ASP GLN PHE GLU ALA LYS ARG ALA LYS SER LYS ALA SER
SEQRES  14 T  209  ARG GLU ARG LYS ILE ALA ARG ARG GLU GLU ARG LEU ALA
SEQRES  15 T  209  PRO GLY PRO GLU ARG SER CYS THR SER THR SER GLY CYS
SEQRES  16 T  209  SER SER SER CYS GLY THR LYS GLU GLY GLN GLU VAL LYS
SEQRES  17 T  209  PHE
SEQRES   1 U  164  MET PRO ALA GLY HIS GLY LEU ARG SER ARG THR ARG ASP
SEQRES   2 U  164  LEU PHE ALA ARG PRO PHE ARG LYS LYS GLY TYR ILE PRO
SEQRES   3 U  164  LEU THR THR TYR LEU ARG THR TYR LYS VAL GLY GLU HIS
SEQRES   4 U  164  VAL ASP VAL LYS VAL ASN GLY ALA VAL HIS LYS GLY MET
SEQRES   5 U  164  PRO HIS LYS PHE TYR HIS GLY ARG THR GLY ARG VAL TRP
SEQRES   6 U  164  ASN VAL THR LYS ARG ALA ILE GLY VAL GLU ILE ASN LYS
SEQRES   7 U  164  GLN VAL GLY ASN ARG ILE ILE LYS LYS ARG ILE HIS VAL
SEQRES   8 U  164  ARG VAL GLU HIS VAL GLN PRO SER ARG CYS ASN GLU GLU
SEQRES   9 U  164  PHE LEU GLN ARG LYS LEU ASN ASN ASP LYS LEU LYS ALA
SEQRES  10 U  164  GLU ALA LYS ALA ARG GLY GLU VAL ILE SER THR LYS ARG
SEQRES  11 U  164  GLN PRO ALA GLY PRO LYS PRO GLY PHE MET VAL GLU GLY
SEQRES  12 U  164  THR THR ILE GLU THR VAL THR PRO ILE PRO TYR ASP VAL
SEQRES  13 U  164  VAL ASN ASP LEU LYS GLY GLY TYR
SEQRES   1 V  171  MET VAL LYS TYR SER ARG GLU ALA ASN ASN PRO THR LYS
SEQRES   2 V  171  SER SER LYS ALA MET GLY ARG ASP LEU ARG VAL HIS PHE
SEQRES   3 V  171  LYS ASN THR ARG GLU THR ALA PHE ALA ILE ARG LYS LEU
SEQRES   4 V  171  PRO LEU GLY LYS ALA LYS ARG TYR LEU GLU ASP VAL ILE
SEQRES   5 V  171  ALA HIS LYS GLN ALA ILE PRO PHE ARG ARG TYR CYS GLY
SEQRES   6 V  171  GLY VAL GLY ARG THR ALA GLN ALA LYS SER ARG HIS SER
SEQRES   7 V  171  ASN GLY GLN GLY ARG TRP PRO ALA LYS SER ALA ARG PHE
SEQRES   8 V  171  ILE LEU ASP LEU LEU LYS ASN ALA GLU SER ASN ALA GLU
SEQRES   9 V  171  VAL LYS GLY LEU ASP VAL ASP THR LEU TYR VAL SER HIS
SEQRES  10 V  171  ILE GLN VAL ASN GLN ALA GLN LYS GLN ARG ARG ARG THR
SEQRES  11 V  171  TYR ARG ALA HIS GLY ARG ILE ASN PRO TYR MET SER SER
SEQRES  12 V  171  PRO CYS HIS ILE GLU LEU ILE LEU SER GLU LYS GLU GLU
SEQRES  13 V  171  PRO VAL LYS LYS GLU PRO GLU SER GLN ILE ALA ALA ARG
SEQRES  14 V  171  LYS ALA
SEQRES   1 X  152  MET ALA PRO LYS ALA ALA VAL LYS LYS ALA ASP GLY LYS
SEQRES   2 X  152  THR GLN GLN ALA LEU LYS VAL ALA LYS ALA VAL LYS SER
SEQRES   3 X  152  GLY SER ILE LYS ARG LYS SER LYS LYS ILE ARG THR SER
SEQRES   4 X  152  VAL THR PHE HIS ARG PRO LYS THR LEU LYS LYS ALA ARG
SEQRES   5 X  152  ASP PRO LYS TYR PRO ARG VAL SER ALA PRO GLY ARG ASN
SEQRES   6 X  152  LYS LEU ASP GLN TYR GLN ILE LEU LYS TYR PRO LEU THR
SEQRES   7 X  152  THR GLU SER ALA MET LYS LYS ILE GLU ASP ASN ASN THR
SEQRES   8 X  152  LEU VAL PHE ILE VAL ASP LEU LYS ALA ASP LYS LYS LYS
SEQRES   9 X  152  ILE LYS ALA ALA VAL LYS LYS MET TYR ASP ILE GLN ALA
SEQRES  10 X  152  LYS LYS VAL ASN THR LEU ILE ARG PRO ASP GLY LYS LYS
SEQRES  11 X  152  LYS ALA TYR VAL LYS LEU THR PRO ASP TYR ASP ALA LEU
SEQRES  12 X  152  ASP VAL ALA ASN LYS ILE GLY ILE ILE
SEQRES   1 Z  162  MET VAL LEU LYS THR GLU LEU CYS ARG PHE SER GLY GLN
SEQRES   2 Z  162  LYS ILE TYR PRO GLY LYS GLY ILE ARG PHE ILE ARG ALA
SEQRES   3 Z  162  ASP SER GLN VAL PHE LEU PHE ALA ASN SER LYS CYS LYS
SEQRES   4 Z  162  ARG TYR PHE HIS ASN ARG LEU LYS PRO ALA LYS LEU THR
SEQRES   5 Z  162  TRP THR ALA MET TYR ARG LYS GLN HIS LYS LYS ASP ILE
SEQRES   6 Z  162  HIS ALA GLU ALA VAL LYS LYS ARG ARG ARG THR THR LYS
SEQRES   7 Z  162  LYS PRO TYR SER ARG SER ILE VAL GLY ALA THR LEU GLU
SEQRES   8 Z  162  VAL ILE GLN LYS LYS ARG SER GLU LYS PRO GLU VAL ARG
SEQRES   9 Z  162  ASP ALA ALA ARG GLU ALA ALA LEU ARG GLU ILE LYS GLU
SEQRES  10 Z  162  ARG ILE LYS LYS THR LYS ASP GLU LYS LYS ALA LYS LYS
SEQRES  11 Z  162  ALA GLU VAL ALA LYS SER GLN LYS THR GLN SER LYS GLY
SEQRES  12 Z  162  GLY ALA THR GLN ARG GLY ALA LYS GLY PRO LYS ILE GLY
SEQRES  13 Z  162  GLY GLY GLY GLY LYS ARG
SEQRES   1 Y  150  MET LYS ARG ASN PRO ARG VAL THR SER SER ARG ARG LYS
SEQRES   2 Y  150  CYS ARG LYS ALA HIS PHE THR ALA PRO SER SER VAL ARG
SEQRES   3 Y  150  ARG VAL LEU MET SER ALA ALA LEU SER THR GLU LEU ARG
SEQRES   4 Y  150  HIS LYS TYR ASN VAL ARG SER ILE PRO ILE ARG LYS ASP
SEQRES   5 Y  150  ASP GLU VAL GLN VAL VAL ARG GLY SER TYR LYS GLY ARG
SEQRES   6 Y  150  GLU GLY LYS VAL VAL GLN VAL TYR ARG ARG ARG TRP VAL
SEQRES   7 Y  150  ILE HIS VAL GLU ARG ILE THR ARG GLU LYS VAL ASN GLY
SEQRES   8 Y  150  SER THR VAL ASN VAL GLY ILE HIS PRO SER LYS VAL VAL
SEQRES   9 Y  150  VAL THR LYS LEU LYS LEU ASP LYS ASP ARG LYS ALA ILE
SEQRES  10 Y  150  LEU ASP ARG LYS ALA SER GLY ARG ALA ALA ASP LYS ALA
SEQRES  11 Y  150  LYS GLY LYS PHE THR ALA GLU ASP VAL ALA ALA ALA GLY
SEQRES  12 Y  150  ALA SER LEU GLN GLU ILE ASP
SEQRES   1 b  147  MET ALA THR VAL PRO GLU PRO LEU ILE TRP GLU ILE VAL
SEQRES   2 b  147  LYS LYS ASN ASN CYS PHE LEU VAL LYS GLN PHE GLY ASN
SEQRES   3 b  147  SER ASN ALA LYS VAL GLN PHE THR LYS GLU PRO ASN ASN
SEQRES   4 b  147  LEU TYR ASN VAL HIS SER TYR LYS HIS SER GLY LEU ALA
SEQRES   5 b  147  ASN LYS LYS THR VAL THR ILE GLN PRO SER GLY VAL LYS
SEQRES   6 b  147  ASP ALA ALA VAL VAL LEU SER THR THR LYS THR LYS LYS
SEQRES   7 b  147  GLN ASN ALA PRO ALA LYS LEU TYR HIS LYS SER VAL MET
SEQRES   8 b  147  ARG LYS GLU PHE ARG LYS MET ALA LYS ALA VAL LYS ASN
SEQRES   9 b  147  GLN VAL SER ASP ASN TYR TYR ARG PRO ASP LEU THR LYS
SEQRES  10 b  147  PRO ALA LEU ALA ARG LEU SER SER VAL TYR ARG SER LEU
SEQRES  11 b  147  GLN VAL SER LYS SER GLY ALA LYS LYS LYS ASN ARG GLN
SEQRES  12 b  147  PRO THR LYS LEU
SEQRES   1 d   60  MET ALA LYS SER LYS ASN HIS THR ALA HIS ASN GLN SER
SEQRES   2 d   60  TYR LYS ALA HIS LYS ASN GLY ILE LYS LYS PRO LYS ARG
SEQRES   3 d   60  HIS ARG GLN THR SER THR LYS GLY MET ASP PRO LYS PHE
SEQRES   4 d   60  LEU ARG ASN GLN ARG TYR SER ARG LYS HIS ASN LYS LYS
SEQRES   5 d   60  SER GLY GLU ALA GLU SER GLU GLU
SEQRES   1 f  112  MET ALA PRO THR LYS LYS ALA LYS LYS SER GLY GLU ASN
SEQRES   2 f  112  ILE ASN ASN LYS LEU GLN LEU VAL MET LYS SER GLY LYS
SEQRES   3 f  112  TYR THR LEU GLY TYR LYS THR VAL LEU LYS THR LEU ARG
SEQRES   4 f  112  SER SER LEU GLY LYS LEU ILE ILE LEU ALA ASN ASN CYS
SEQRES   5 f  112  PRO PRO LEU ARG LYS SER GLU ILE GLU THR TYR ALA MET
SEQRES   6 f  112  LEU ALA LYS ILE SER VAL HIS HIS PHE HIS GLY ASN ASN
SEQRES   7 f  112  VAL ASP LEU GLY THR ALA CYS GLY LYS TYR TYR ARG VAL
SEQRES   8 f  112  CYS CYS LEU SER ILE LEU ASP PRO GLY ASP SER ASP ILE
SEQRES   9 f  112  ILE SER THR THR THR THR THR GLN
SEQRES   1 g  123  MET SER GLU LYS LYS ARG GLY ALA GLY THR ARG LYS ASP
SEQRES   2 g  123  GLU VAL VAL THR ARG GLU TYR THR ILE ASN LEU HIS LYS
SEQRES   3 g  123  ARG LEU HIS GLY CYS THR PHE LYS LYS LYS ALA PRO ASN
SEQRES   4 g  123  ALA ILE LYS GLU ILE ARG LYS PHE ALA GLN LYS ALA MET
SEQRES   5 g  123  GLY THR THR ASP ILE ARG ILE ASP VAL LYS LEU ASN LYS
SEQRES   6 g  123  ALA ILE TRP THR ASN GLY ILE ARG SER VAL PRO ARG ARG
SEQRES   7 g  123  VAL ARG VAL ARG ILE SER ARG LYS ARG ASN ASP GLU GLU
SEQRES   8 g  123  ASP ALA LYS GLU GLU LEU TYR SER LEU VAL THR VAL ALA
SEQRES   9 g  123  GLU ILE PRO ALA GLU GLY LEU LYS GLY LEU GLY THR LYS
SEQRES  10 g  123  VAL VAL GLU ASP GLU GLU
SEQRES   1 h  133  MET ALA VAL PRO LEU LEU THR LYS LYS ILE VAL LYS LYS
SEQRES   2 h  133  ARG VAL LYS GLN PHE LYS ARG PRO HIS SER ASP ARG TYR
SEQRES   3 h  133  ILE GLY LEU LYS THR SER TRP ARG ARG PRO LYS GLY ILE
SEQRES   4 h  133  ASP SER ARG VAL ARG ARG LYS PHE LYS GLY CYS THR LEU
SEQRES   5 h  133  MET PRO ASN ILE GLY TYR GLY SER ASP LYS LYS THR ARG
SEQRES   6 h  133  HIS TYR LEU PRO ASN LYS PHE LYS LYS PHE VAL VAL HIS
SEQRES   7 h  133  ASN VAL SER GLU LEU GLU LEU LEU MET MET HIS ASN ARG
SEQRES   8 h  133  THR TYR CYS ALA GLU ILE ALA HIS ASN VAL SER THR ARG
SEQRES   9 h  133  LYS ARG LYS GLU ILE VAL GLU ARG ALA ALA GLN LEU ASP
SEQRES  10 h  133  ILE VAL VAL THR ASN LYS LEU ALA ARG LEU ARG SER GLN
SEQRES  11 h  133  GLU ASP GLU
SEQRES   1 l   94  MET GLY LYS GLY THR GLY SER PHE GLY LYS ARG ARG ASN
SEQRES   2 l   94  LYS THR HIS THR LEU CYS VAL ARG CYS GLY ARG ARG SER
SEQRES   3 l   94  PHE HIS LEU GLN LYS SER THR CYS SER SER CYS GLY TYR
SEQRES   4 l   94  PRO ALA ALA ARG ILE ARG LYS TYR ASN TRP SER VAL LYS
SEQRES   5 l   94  ALA ILE ARG ARG LYS THR THR GLY THR GLY ARG MET ARG
SEQRES   6 l   94  TYR MET ARG HIS VAL PRO ARG ARG PHE LYS SER ASN PHE
SEQRES   7 l   94  ARG GLU GLY THR GLU ALA THR PRO ARG LYS ARG ALA ALA
SEQRES   8 l   94  ALA ALA ASN
SEQRES   1 n   69  MET PRO LYS GLN ILE HIS GLU ILE LYS ASP PHE LEU LEU
SEQRES   2 n   69  THR ALA ARG ARG LYS ASP ALA ARG SER VAL ARG ILE LYS
SEQRES   3 n   69  ARG THR LYS ASP ALA VAL LYS PHE LYS VAL ARG CYS SER
SEQRES   4 n   69  LYS TYR LEU TYR THR LEU CYS VAL PHE ASP ALA ASP LYS
SEQRES   5 n   69  ALA ASN LYS LEU LYS GLN SER LEU PRO PRO GLY LEU THR
SEQRES   6 n   69  VAL GLN GLU VAL
SEQRES   1 o   51  MET PRO SER HIS LYS THR PHE ARG ILE LYS GLN LYS LEU
SEQRES   2 o   51  ALA LYS LYS GLN ARG GLN ASN ARG PRO ILE PRO TYR TRP
SEQRES   3 o   51  ILE ARG MET ARG THR ASP ASN THR ILE ARG TYR ASN ALA
SEQRES   4 o   51  LYS ARG ARG HIS TRP ARG ARG THR LYS LEU GLY PHE
SEQRES   1 r  105  MET VAL ASN VAL PRO LYS THR LYS LYS THR TYR CYS LYS
SEQRES   2 r  105  ASN LYS GLU CYS ARG LYS HIS THR LEU HIS LYS VAL THR
SEQRES   3 r  105  GLN TYR LYS LYS GLY LYS ASP SER LEU SER ALA GLN GLY
SEQRES   4 r  105  LYS ARG ARG TYR ASP ARG LYS GLN SER GLY TYR GLY GLY
SEQRES   5 r  105  GLN THR LYS PRO VAL PHE HIS LYS LYS ALA LYS THR THR
SEQRES   6 r  105  LYS LYS ILE VAL LEU LYS LEU GLN CYS GLN SER CYS LYS
SEQRES   7 r  105  HIS TYR SER GLN HIS PRO ILE LYS ARG CYS LYS HIS PHE
SEQRES   8 r  105  GLU ILE GLY GLY ASP LYS LYS GLY LYS GLY THR SER LEU
SEQRES   9 r  105  PHE
SEQRES   1 q   25  MET ARG ALA LYS TRP LYS LYS LYS ARG MET ARG ARG LEU
SEQRES   2 q   25  LYS ARG LYS ARG ARG LYS MET ARG GLN ARG SER LYS
SEQRES   1 y   20  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   2 y   20  UNK UNK UNK UNK UNK UNK UNK
SEQRES   1 z   14  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   2 z   14  UNK
SEQRES   1 G  219  MET ALA PRO THR SER LYS MET ALA LEU GLY ILE LYS ARG
SEQRES   2 G  219  ALA SER ARG SER HIS THR TYR HIS ARG ARG GLY LEU TRP
SEQRES   3 G  219  ALA ILE LYS ALA LYS HIS GLY GLY ALA LEU PRO LYS ALA
SEQRES   4 G  219  GLU LYS PRO ALA ALA ILE ALA GLU PRO LYS PHE TYR PRO
SEQRES   5 G  219  ALA ASP ASP VAL LYS PRO ARG THR VAL SER THR ARG LYS
SEQRES   6 G  219  PRO HIS PRO THR LYS LEU ARG SER THR ILE THR PRO GLY
SEQRES   7 G  219  THR VAL LEU ILE LEU LEU ALA GLY ARG TYR MET GLY LYS
SEQRES   8 G  219  ARG VAL VAL PHE LEU LYS GLN LEU GLN SER GLY LEU LEU
SEQRES   9 G  219  LEU ILE THR GLY PRO PHE LYS ILE ASN GLY VAL PRO ILE
SEQRES  10 G  219  ARG ARG VAL ASN GLN ALA TYR VAL ILE ALA THR SER THR
SEQRES  11 G  219  LYS VAL ASP ILE SER LYS VAL ASN VAL GLN LYS PHE ASP
SEQRES  12 G  219  ASP LYS TYR PHE ALA ARG GLU LYS LYS THR ARG ALA LYS
SEQRES  13 G  219  LYS THR GLU GLY GLU LEU PHE GLU SER ASP LYS GLU ALA
SEQRES  14 G  219  THR LYS ASN LEU PRO ASP PHE LYS LYS ASP ASP GLN LYS
SEQRES  15 G  219  VAL ILE ASP ALA GLU LEU ILE LYS ALA ILE ASP ALA VAL
SEQRES  16 G  219  PRO ASP LEU LYS ASN TYR LEU GLY ALA ARG PHE SER LEU
SEQRES  17 G  219  ARG ASP GLY ASP LYS PRO HIS GLU MET THR PHE
SEQRES   1 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   2 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   3 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   4 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   5 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   6 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   7 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   8 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   9 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  10 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  11 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  12 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  13 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  14 L  183  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES  15 L  183  UNK
SEQRES   1 N  134  MET PRO PHE LYS ARG PHE VAL GLU ILE GLY ARG VAL ALA
SEQRES   2 N  134  LEU VAL ASN TYR GLY LYS ASP TYR GLY ARG LEU VAL VAL
SEQRES   3 N  134  ILE VAL ASP VAL VAL ASP GLN ASN ARG ALA LEU VAL ASP
SEQRES   4 N  134  ALA PRO ASP MET VAL ARG CYS GLN ILE ASN PHE LYS ARG
SEQRES   5 N  134  LEU SER LEU THR ASP ILE LYS ILE ASP ILE LYS ARG VAL
SEQRES   6 N  134  PRO LYS LYS THR THR LEU ILE LYS ALA MET GLU GLU ALA
SEQRES   7 N  134  ASP VAL LYS ASN LYS TRP GLU ASN SER SER TRP GLY LYS
SEQRES   8 N  134  LYS LEU ILE VAL GLN LYS ARG ARG ALA SER LEU ASN ASP
SEQRES   9 N  134  PHE ASP ARG PHE LYS VAL MET LEU ALA LYS ILE LYS ARG
SEQRES  10 N  134  GLY GLY ALA ILE ARG GLN GLU LEU ALA LYS LEU LYS LYS
SEQRES  11 N  134  THR ALA ALA ALA
SEQRES   1 S  178  MET GLY ALA PHE ARG PHE HIS GLN TYR GLN VAL VAL GLY
SEQRES   2 S  178  ARG GLY LEU PRO THR PRO THR ASP GLU HIS PRO LYS ILE
SEQRES   3 S  178  TYR ARG MET LYS LEU TRP ALA THR ASN GLU VAL ARG ALA
SEQRES   4 S  178  LYS SER LYS PHE TRP TYR PHE LEU ARG LYS LEU LYS LYS
SEQRES   5 S  178  VAL LYS LYS SER ASN GLY GLN ILE LEU ALA ILE ASN GLU
SEQRES   6 S  178  ILE PHE GLU LYS ASN PRO THR THR ILE LYS ASN TYR GLY
SEQRES   7 S  178  ILE TRP LEU ARG TYR GLN SER ARG THR GLY TYR HIS ASN
SEQRES   8 S  178  MET TYR LYS GLU TYR ARG ASP THR THR LEU ASN GLY ALA
SEQRES   9 S  178  VAL GLU GLN MET TYR THR GLU MET ALA SER ARG HIS ARG
SEQRES  10 S  178  VAL ARG PHE PRO CYS ILE GLN ILE ILE LYS THR ALA THR
SEQRES  11 S  178  VAL HIS PHE LYS LEU CYS LYS ARG ASP ASN THR LYS GLN
SEQRES  12 S  178  PHE HIS LYS SER ASP ILE LYS PHE PRO LEU VAL TYR ARG
SEQRES  13 S  178  LYS VAL ARG PRO PRO THR ARG LYS LEU LYS THR THR PHE
SEQRES  14 S  178  LYS ALA SER ARG PRO ASN LEU PHE MET
SEQRES   1 W  130  MET ALA ARG GLY VAL ALA VAL ALA ALA LYS GLY GLY ALA
SEQRES   2 W  130  GLY GLY LYS LYS LYS GLY SER VAL SER PHE VAL ILE ASP
SEQRES   3 W  130  CYS SER LYS PRO VAL GLU ASP LYS ILE MET GLU ILE ALA
SEQRES   4 W  130  SER LEU GLU LYS PHE LEU GLN GLU ARG ILE LYS VAL ALA
SEQRES   5 W  130  GLY GLY LYS ALA GLY ASN LEU GLY ASP SER VAL THR VAL
SEQRES   6 W  130  THR ARG ASP LYS THR LYS VAL THR VAL THR SER ASP GLY
SEQRES   7 W  130  ALA PHE SER LYS ARG TYR LEU LYS TYR LEU THR LYS LYS
SEQRES   8 W  130  TYR LEU LYS LYS HIS ASN VAL ARG ASP TRP LEU ARG VAL
SEQRES   9 W  130  ILE ALA ALA ASN LYS ASP ARG ASN VAL TYR GLU LEU ARG
SEQRES  10 W  130  TYR PHE ASN ILE ALA GLU ASN GLU GLY GLU GLU GLU ASP
SEQRES   1 a  136  MET VAL LYS PHE LEU LYS PRO GLY LYS ALA VAL ILE LEU
SEQRES   2 a  136  LEU GLN GLY ARG PHE ALA GLY ARG LYS ALA VAL ILE VAL
SEQRES   3 a  136  ARG VAL PHE GLU GLU GLY THR ARG ASP ARG PRO TYR GLY
SEQRES   4 a  136  HIS CYS LEU VAL ALA GLY LEU ALA LYS TYR PRO LYS LYS
SEQRES   5 a  136  VAL ILE ARG LYS ASP SER ALA LYS LYS THR ALA LYS LYS
SEQRES   6 a  136  SER ARG VAL LYS CYS PHE LEU LYS LEU VAL ASN PHE THR
SEQRES   7 a  136  HIS LEU MET PRO THR ARG TYR THR LEU ASP VAL ASP LEU
SEQRES   8 a  136  LYS GLU VAL ALA ALA GLY PRO ASP ALA LEU ALA THR ARG
SEQRES   9 a  136  ASP LYS LYS VAL ALA ALA CYS LYS SER ALA LYS ALA ARG
SEQRES  10 a  136  LEU GLU ASP ARG PHE LYS THR GLY LYS ASN ARG TRP PHE
SEQRES  11 a  136  PHE THR LYS LEU ARG PHE
SEQRES   1 i  119  MET VAL GLN ARG LEU THR TYR ARG LYS ARG HIS SER TYR
SEQRES   2 i  119  ALA THR LYS SER ASN GLN THR ARG VAL VAL LYS THR PRO
SEQRES   3 i  119  GLY GLY LYS LEU VAL TYR GLN TYR THR LYS LYS ARG ALA
SEQRES   4 i  119  SER GLY PRO LYS CYS PRO VAL THR GLY LYS LYS ILE GLN
SEQRES   5 i  119  GLY ILE PRO HIS LEU ARG PRO THR GLU TYR LYS ARG PRO
SEQRES   6 i  119  ARG LEU SER ARG ASN ARG ARG THR VAL ASN ARG PRO TYR
SEQRES   7 i  119  GLY GLY VAL LEU SER GLY PRO ALA VAL ARG GLU ARG ILE
SEQRES   8 i  119  ILE ARG ALA PHE LEU VAL GLU GLU GLN LYS ILE VAL LYS
SEQRES   9 i  119  LYS VAL LEU LYS ILE GLN LYS THR LYS GLU LYS THR THR
SEQRES  10 i  119  LYS SER
SEQRES   1 j  111  MET LYS GLY ARG GLN GLY GLN ARG VAL ARG LEU TYR VAL
SEQRES   2 j  111  ARG GLY THR ILE LEU GLY TYR LYS ARG SER LYS SER ASN
SEQRES   3 j  111  GLN TYR GLU ASN THR SER LEU LEU GLN ILE GLU GLY VAL
SEQRES   4 j  111  ASN THR LYS GLU GLU VAL GLY TRP TYR ALA GLY LYS ARG
SEQRES   5 j  111  ILE ALA TYR VAL TYR LYS ALA LYS THR LYS SER ASN ASP
SEQRES   6 j  111  SER THR ILE ARG CYS ILE TRP GLY LYS VAL THR ARG PRO
SEQRES   7 j  111  HIS GLY ASN SER GLY VAL VAL ARG ALA LYS PHE ARG SER
SEQRES   8 j  111  ASN LEU PRO PRO THR SER MET GLY LYS LYS VAL ARG VAL
SEQRES   9 j  111  PHE MET TYR PRO SER SER ILE
SEQRES   1 k  112  MET ALA PRO SER GLN PRO LYS SER GLY LEU PHE VAL GLY
SEQRES   2 k  112  ILE ASN LYS GLY HIS VAL VAL THR LYS ARG GLU LEU PRO
SEQRES   3 k  112  PRO ARG PRO SER ASP ARG LYS GLY LYS GLY THR LYS ARG
SEQRES   4 k  112  VAL HIS PHE VAL ARG ASN LEU ILE ARG GLU VAL ALA GLY
SEQRES   5 k  112  PHE ALA PRO TYR GLU LYS ARG ILE THR GLU LEU LEU LYS
SEQRES   6 k  112  VAL GLY LYS ASP LYS ARG ALA LEU LYS VAL ALA LYS ARG
SEQRES   7 k  112  LYS LEU GLY THR HIS LYS ARG ALA LYS LYS LYS ARG GLU
SEQRES   8 k  112  GLU MET SER SER VAL LEU ARG LYS MET ARG SER ALA GLY
SEQRES   9 k  112  GLY GLY ALA GLY ASP LYS LYS LYS
SEQRES   1 p   53  ILE ILE GLU PRO SER LEU GLN ALA LEU ALA ARG LYS TYR
SEQRES   2 p   53  ASN GLN ASP LYS MET ILE CYS ARG LYS CYS TYR ALA ARG
SEQRES   3 p   53  LEU HIS PRO ARG ALA VAL ASN CYS ARG LYS LYS LYS CYS
SEQRES   4 p   53  GLY HIS SER ASN GLN LEU ARG PRO LYS LYS LYS ILE LYS
SEQRES   5 p   53  ASN
SEQRES   1 x   20  UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES   2 x   20  UNK UNK UNK UNK UNK UNK UNK
SEQRES   1 J  166  MET PRO PRO LYS LEU ASP PRO THR GLN VAL VAL ASP VAL
SEQRES   2 J  166  PHE VAL ARG VAL THR GLY GLY GLU VAL GLY ALA ALA SER
SEQRES   3 J  166  SER LEU ALA PRO LYS ILE GLY PRO LEU GLY LEU SER PRO
SEQRES   4 J  166  LYS LYS ILE GLY GLU ASP ILE ALA LYS GLU THR ALA LYS
SEQRES   5 J  166  ASP TRP LYS GLY LEU ARG VAL THR VAL LYS LEU THR VAL
SEQRES   6 J  166  GLN ASN ARG GLN ALA LYS VAL SER VAL VAL PRO SER ALA
SEQRES   7 J  166  ALA ALA LEU VAL ILE LYS ALA LEU LYS GLU PRO GLU ARG
SEQRES   8 J  166  ASP ARG LYS LYS VAL LYS ASN ILE LYS HIS SER GLY ASN
SEQRES   9 J  166  ILE SER LEU ASP ASP VAL ILE GLU ILE ALA ARG ILE MET
SEQRES  10 J  166  ARG ASN ARG SER MET ALA LYS GLU MET ALA GLY THR VAL
SEQRES  11 J  166  LYS GLU ILE LEU GLY THR CYS VAL SER VAL GLY CYS THR
SEQRES  12 J  166  VAL ASP GLY LYS ASP PRO LYS ASP LEU GLN GLN GLU ILE
SEQRES  13 J  166  SER ASP GLY GLU VAL GLU ILE PRO SER ALA
SEQRES   1 t  110  MET SER SER SER GLU VAL ALA CYS THR LEU ALA ALA LEU
SEQRES   2 t  110  ILE LEU HIS ASP ASP GLY ILE PRO ILE THR SER GLU LYS
SEQRES   3 t  110  ILE ALA THR VAL VAL LYS ALA ALA GLY ILE LYS VAL GLU
SEQRES   4 t  110  ALA TYR TRP PRO ALA LEU PHE ALA LYS LEU LEU GLU LYS
SEQRES   5 t  110  ARG SER VAL ASP ASP LEU ILE LEU SER VAL GLY SER GLY
SEQRES   6 t  110  GLY GLY GLY ALA PRO ALA ALA ALA ALA ALA ALA PRO ALA
SEQRES   7 t  110  ALA GLY GLY ALA ALA ALA ALA GLU GLU LYS LYS GLU GLU
SEQRES   8 t  110  LYS LYS GLU GLU ALA LYS GLU GLU SER ASP ASP ASP MET
SEQRES   9 t  110  GLY PHE SER LEU PHE ASP
SEQRES   1 u  110  MET SER SER SER GLU VAL ALA CYS THR LEU ALA ALA LEU
SEQRES   2 u  110  ILE LEU HIS ASP ASP GLY ILE PRO ILE THR SER GLU LYS
SEQRES   3 u  110  ILE ALA THR VAL VAL LYS ALA ALA GLY ILE LYS VAL GLU
SEQRES   4 u  110  ALA TYR TRP PRO ALA LEU PHE ALA LYS LEU LEU GLU LYS
SEQRES   5 u  110  ARG SER VAL ASP ASP LEU ILE LEU SER VAL GLY SER GLY
SEQRES   6 u  110  GLY GLY GLY ALA PRO ALA ALA ALA ALA ALA ALA PRO ALA
SEQRES   7 u  110  ALA GLY GLY ALA ALA ALA ALA GLU GLU LYS LYS GLU GLU
SEQRES   8 u  110  LYS LYS GLU GLU ALA LYS GLU GLU SER ASP ASP ASP MET
SEQRES   9 u  110  GLY PHE SER LEU PHE ASP
SEQRES   1 v  113  MET LYS PHE ILE ALA ALA TYR LEU LEU ALA TYR LEU SER
SEQRES   2 v  113  GLY ASN ALA SER PRO SER ALA GLU ASP LEU THR SER ILE
SEQRES   3 v  113  LEU GLU SER VAL GLY CYS GLU ILE ASP ASN GLU LYS MET
SEQRES   4 v  113  GLU LEU MET LEU SER GLN VAL LYS GLY LYS ASP ILE THR
SEQRES   5 v  113  GLU LEU LEU ALA ALA GLY ARG GLU LYS PHE ALA ALA VAL
SEQRES   6 v  113  PRO SER GLY GLY GLY GLY VAL ALA VAL SER ALA ALA ALA
SEQRES   7 v  113  PRO ALA ALA GLY GLY ALA ALA ALA PRO ALA ALA GLU SER
SEQRES   8 v  113  LYS LYS GLU GLU LYS VAL VAL GLU LYS GLU GLU SER ASP
SEQRES   9 v  113  ASP ASP MET GLY PHE SER LEU PHE ASP
SEQRES   1 w  113  MET LYS PHE ILE ALA ALA TYR LEU LEU ALA TYR LEU SER
SEQRES   2 w  113  GLY ASN ALA SER PRO SER ALA GLU ASP LEU THR SER ILE
SEQRES   3 w  113  LEU GLU SER VAL GLY CYS GLU ILE ASP ASN GLU LYS MET
SEQRES   4 w  113  GLU LEU MET LEU SER GLN VAL LYS GLY LYS ASP ILE THR
SEQRES   5 w  113  GLU LEU LEU ALA ALA GLY ARG GLU LYS PHE ALA ALA VAL
SEQRES   6 w  113  PRO SER GLY GLY GLY GLY VAL ALA VAL SER ALA ALA ALA
SEQRES   7 w  113  PRO ALA ALA GLY GLY ALA ALA ALA PRO ALA ALA GLU SER
SEQRES   8 w  113  LYS LYS GLU GLU LYS VAL VAL GLU LYS GLU GLU SER ASP
SEQRES   9 w  113  ASP ASP MET GLY PHE SER LEU PHE ASP
SEQRES   1 c  124  MET SER SER GLY LYS VAL LYS ALA GLY GLU LEU TRP ASN
SEQRES   2 c  124  LYS SER LYS ASP ASP LEU THR LYS GLN LEU ALA GLU LEU
SEQRES   3 c  124  LYS THR GLU LEU GLY GLN LEU ARG ILE GLN LYS VAL ALA
SEQRES   4 c  124  SER SER GLY SER LYS LEU ASN ARG ILE HIS ASP ILE ARG
SEQRES   5 c  124  LYS SER ILE ALA ARG VAL LEU THR VAL ILE ASN ALA LYS
SEQRES   6 c  124  GLN ARG ALA GLN LEU ARG LEU PHE TYR LYS ASN LYS LYS
SEQRES   7 c  124  TYR ALA PRO LEU ASP LEU ARG ALA LYS GLN THR ARG ALA
SEQRES   8 c  124  ILE ARG ARG ARG LEU SER PRO ASP GLU LYS SER ARG VAL
SEQRES   9 c  124  LEU GLU LYS THR LYS LYS ARG THR VAL HIS PHE PRO GLN
SEQRES  10 c  124  ARG LYS PHE ALA ILE LYS ALA
SEQRES   1 e  244  MET ALA SER GLU ALA ALA LYS VAL ALA VAL PRO GLU LYS
SEQRES   2 e  244  VAL ILE LEU LYS ARG ARG ARG GLU GLU VAL TRP ALA ALA
SEQRES   3 e  244  GLU LYS LYS GLN LYS VAL ALA ALA GLU LYS ILE LYS ALA
SEQRES   4 e  244  ALA GLU ASN THR LYS VAL ILE TYR ALA ARG ALA GLU GLN
SEQRES   5 e  244  TYR ALA GLY GLU TYR GLU ALA GLN ASP LYS GLU LEU VAL
SEQRES   6 e  244  GLN LEU LYS ARG GLU ALA ARG MET LYS GLY GLY PHE TYR
SEQRES   7 e  244  VAL SER PRO GLU ALA LYS PRO LEU PHE VAL VAL ARG ILE
SEQRES   8 e  244  ARG GLY ILE ASN ALA MET HIS PRO LYS THR LYS LYS ILE
SEQRES   9 e  244  LEU GLN LEU LEU ARG LEU ARG GLN ILE PHE ASN GLY VAL
SEQRES  10 e  244  PHE LEU LYS VAL ASN LYS ALA THR ILE ASN MET LEU ARG
SEQRES  11 e  244  ARG VAL GLU PRO TYR VAL THR TYR GLY TYR PRO ASN LEU
SEQRES  12 e  244  LYS SER VAL ARG GLU LEU ILE TYR LYS ARG GLY TYR GLY
SEQRES  13 e  244  LYS LEU ASN LYS GLN ARG ILE PRO LEU ALA ASN ASN LYS
SEQRES  14 e  244  VAL ILE GLU GLU GLY LEU GLY LYS HIS ASN ILE ILE CYS
SEQRES  15 e  244  ILE GLU ASP LEU VAL HIS GLU ILE LEU THR VAL GLY PRO
SEQRES  16 e  244  HIS PHE LYS GLU ALA ASN ASN PHE LEU TRP PRO PHE LYS
SEQRES  17 e  244  LEU LYS ALA PRO LEU GLY GLY LEU LYS LYS LYS ARG ASN
SEQRES  18 e  244  HIS TYR VAL GLU GLY GLY ASP ALA GLY ASN ARG GLU ASN
SEQRES  19 e  244  TYR ILE ASN GLN LEU VAL ARG ARG MET ASN
SEQRES   1 s  319  MET ALA ILE LYS ARG THR LYS ALA GLU LYS LYS VAL ALA
SEQRES   2 s  319  TYR ASP LYS LYS LEU CYS GLN LEU LEU ASP GLU TYR THR
SEQRES   3 s  319  LYS VAL LEU ILE ALA VAL ALA ASP ASN VAL GLY SER ASN
SEQRES   4 s  319  GLN LEU GLN GLU ILE ARG LYS GLY LEU ARG GLY ASP SER
SEQRES   5 s  319  ILE VAL LEU MET GLY LYS ASN THR LEU ILE ARG ARG CYS
SEQRES   6 s  319  ILE LYS VAL HIS ALA ASP ASN THR GLY ASN LYS GLU PHE
SEQRES   7 s  319  LEU GLU LEU MET PRO LEU LEU VAL GLY ASN VAL GLY LEU
SEQRES   8 s  319  ILE PHE THR LYS GLY ASP LEU LYS GLU VAL ARG GLU GLU
SEQRES   9 s  319  VAL ALA LYS TYR LYS VAL GLY ALA PRO ALA ARG VAL GLY
SEQRES  10 s  319  LEU VAL ALA PRO VAL ASP VAL VAL VAL PRO PRO GLY ASN
SEQRES  11 s  319  THR GLY LEU ASP PRO SER GLN THR SER PHE PHE GLN VAL
SEQRES  12 s  319  LEU ASN ILE PRO THR LYS ILE ASN LYS GLY THR VAL GLU
SEQRES  13 s  319  ILE ILE THR PRO VAL GLU LEU ILE LYS LYS GLY ASP LYS
SEQRES  14 s  319  VAL GLY SER SER GLU SER ALA LEU LEU ALA LYS LEU GLY
SEQRES  15 s  319  ILE ARG PRO PHE SER TYR GLY LEU VAL ILE THR ASN VAL
SEQRES  16 s  319  TYR ASP SER GLY SER VAL PHE SER PRO GLU VAL LEU ASP
SEQRES  17 s  319  LEU THR GLU ASP ASP LEU MET GLU LYS PHE ALA SER GLY
SEQRES  18 s  319  VAL SER MET VAL ALA SER VAL SER LEU ALA ILE SER TYR
SEQRES  19 s  319  PRO THR ILE ALA ALA ALA PRO HIS MET PHE LEU ASN GLY
SEQRES  20 s  319  TYR LYS ASN VAL LEU ALA VAL ALA VAL GLU THR GLU TYR
SEQRES  21 s  319  SER TYR PRO HIS ALA ASP LYS ILE LYS GLU TYR LEU LYS
SEQRES  22 s  319  ASP PRO SER LYS PHE ALA VAL ALA ALA PRO VAL ALA ALA
SEQRES  23 s  319  ASP SER GLY ALA ALA ALA PRO SER ALA ALA LYS GLU GLU
SEQRES  24 s  319  GLU LYS LYS GLU GLU PRO GLU GLU GLU SER ASP GLY ASP
SEQRES  25 s  319  LEU GLY MET SER LEU PHE ASP
SEQRES   1 C  389  MET SER HIS ARG LYS PHE GLU HIS PRO ARG HIS GLY SER
SEQRES   2 C  389  LEU GLY PHE LEU PRO ARG LYS ARG CYS SER ARG HIS ARG
SEQRES   3 C  389  GLY LYS VAL LYS SER PHE PRO LYS ASP ASP GLN GLN LYS
SEQRES   4 C  389  PRO CYS HIS LEU THR ALA PHE LEU GLY TYR LYS ALA GLY
SEQRES   5 C  389  MET THR HIS ILE VAL ARG GLU VAL GLU LYS PRO GLY SER
SEQRES   6 C  389  LYS LEU HIS LYS LYS GLU THR CYS GLU ALA VAL THR ILE
SEQRES   7 C  389  ILE GLU THR PRO PRO LEU VAL ILE VAL GLY LEU VAL ALA
SEQRES   8 C  389  TYR VAL LYS THR PRO ARG GLY LEU ARG THR LEU ASN SER
SEQRES   9 C  389  VAL TRP ALA GLN HIS LEU SER GLU ASP VAL ARG ARG ARG
SEQRES  10 C  389  PHE TYR LYS ASN TRP CYS LYS SER LYS LYS LYS ALA PHE
SEQRES  11 C  389  THR LYS TYR ALA LEU LYS TYR ASP SER ASP ALA GLY LYS
SEQRES  12 C  389  LYS GLU ILE GLN LEU GLN LEU GLU LYS MET LYS LYS TYR
SEQRES  13 C  389  ALA THR ILE VAL ARG VAL ILE ALA HIS THR GLN ILE ARG
SEQRES  14 C  389  LYS MET LYS GLY LEU LYS GLN LYS LYS ALA HIS LEU MET
SEQRES  15 C  389  GLU ILE GLN VAL ASN GLY GLY THR ILE ALA ASP LYS VAL
SEQRES  16 C  389  ASP TYR GLY TYR LYS PHE PHE GLU LYS GLU VAL PRO VAL
SEQRES  17 C  389  GLU ALA VAL PHE GLN LYS ASP GLU MET VAL ASP ILE ILE
SEQRES  18 C  389  GLY VAL THR LYS GLY LYS GLY TYR GLU GLY VAL VAL THR
SEQRES  19 C  389  ARG TRP GLY VAL THR ARG LEU PRO ARG LYS THR HIS ARG
SEQRES  20 C  389  GLY LEU ARG LYS VAL ALA CYS ILE GLY ALA TRP HIS PRO
SEQRES  21 C  389  ALA ARG VAL SER TYR THR VAL ALA ARG ALA GLY GLN ASN
SEQRES  22 C  389  GLY TYR HIS HIS ARG THR GLU MET ASN LYS LYS ILE TYR
SEQRES  23 C  389  LYS MET GLY LYS SER GLY GLN GLU SER HIS GLU ALA CYS
SEQRES  24 C  389  THR GLU PHE ASP ARG THR GLU LYS ASP ILE THR PRO MET
SEQRES  25 C  389  GLY GLY PHE PRO HIS TYR GLY VAL VAL LYS GLY ASP TYR
SEQRES  26 C  389  LEU MET ILE LYS GLY CYS CYS VAL GLY PRO LYS LYS ARG
SEQRES  27 C  389  VAL VAL THR LEU ARG GLN SER LEU LEU LYS GLN THR SER
SEQRES  28 C  389  ARG LEU ALA LEU GLU GLU ILE LYS LEU LYS PHE ILE ASP
SEQRES  29 C  389  THR SER SER LYS PHE GLY HIS GLY ARG PHE GLN THR THR
SEQRES  30 C  389  ASP GLU LYS GLN LYS PHE TYR GLY ARG LEU LYS ALA
SEQRES   1 D  405  MET ALA THR GLN THR ARG PRO LEU VAL SER VAL LYS ALA
SEQRES   2 D  405  LEU GLU GLY ASP MET ALA THR ASP ASN SER SER SER LEU
SEQRES   3 D  405  ALA LEU ALA GLU VAL PHE ARG ALA PRO LEU ARG PRO ASP
SEQRES   4 D  405  VAL VAL ARG PHE VAL HIS ARG LEU LEU SER CYS ASN LYS
SEQRES   5 D  405  ARG GLN PRO TYR ALA VAL SER ARG ARG ALA GLY HIS GLN
SEQRES   6 D  405  THR SER ALA GLU SER TRP GLY THR GLY ARG ALA VAL SER
SEQRES   7 D  405  ARG ILE PRO ARG VAL PRO GLY GLY GLY THR HIS ARG ALA
SEQRES   8 D  405  GLY GLN GLY ALA PHE GLY ASN MET CYS ARG GLY GLY ARG
SEQRES   9 D  405  MET PHE ALA PRO THR LYS THR TRP ARG LYS TRP HIS ARG
SEQRES  10 D  405  ARG VAL ASN VAL HIS LEU ARG ARG VAL ALA VAL ALA SER
SEQRES  11 D  405  ALA LEU ALA ALA THR SER VAL PRO SER LEU VAL LEU ALA
SEQRES  12 D  405  ARG GLY HIS ARG ILE GLU THR VAL PRO GLU LEU PRO LEU
SEQRES  13 D  405  VAL ILE SER ASP SER ALA GLU SER ILE GLU LYS THR SER
SEQRES  14 D  405  GLN ALA ILE LYS ILE LEU LYS GLN VAL GLY ALA TYR ALA
SEQRES  15 D  405  ASP ALA GLU LYS ALA LYS ASP SER VAL GLY ILE ARG PRO
SEQRES  16 D  405  GLY LYS GLY LYS MET ARG ASN ARG ARG TYR ILE ASN ARG
SEQRES  17 D  405  LYS GLY PRO LEU ILE VAL TYR GLY THR GLU GLY SER LYS
SEQRES  18 D  405  ILE VAL LYS ALA PHE ARG ASN LEU PRO GLY VAL ASP VAL
SEQRES  19 D  405  ALA ASN VAL GLU ARG LEU ASN LEU LEU ASP LEU ALA PRO
SEQRES  20 D  405  GLY GLY HIS LEU GLY ARG PHE VAL ILE TRP THR GLU SER
SEQRES  21 D  405  ALA PHE LYS LYS LEU GLU GLU VAL TYR GLY THR PHE GLU
SEQRES  22 D  405  ALA PRO SER LEU LYS LYS LYS GLY PHE ILE LEU PRO ARG
SEQRES  23 D  405  PRO LYS MET ALA ASN ALA ASP LEU GLY ARG ILE ILE ASN
SEQRES  24 D  405  SER ASP GLU VAL GLN SER VAL VAL LYS PRO LEU ASN LYS
SEQRES  25 D  405  GLU VAL LYS ARG ARG GLU LYS ARG LYS ASN PRO LEU LYS
SEQRES  26 D  405  ASN VAL ALA ALA VAL LEU LYS LEU ASN PRO TYR PHE GLY
SEQRES  27 D  405  THR ALA ARG LYS MET ALA THR LEU ALA GLU ALA ALA ARG
SEQRES  28 D  405  ILE LYS ALA ARG LYS GLU LYS LEU ASP SER LYS ARG THR
SEQRES  29 D  405  LYS LEU SER PRO GLU GLU ALA ALA LYS VAL LYS ALA ALA
SEQRES  30 D  405  GLY LYS ALA TRP TYR LYS THR MET ILE SER ASP SER ASP
SEQRES  31 D  405  TYR ALA GLU PHE ASP ASN PHE SER LYS TRP LEU GLY VAL
SEQRES  32 D  405  THR GLN
SEQRES   1 K  206  MET VAL SER GLY SER GLY VAL CYS ALA LYS ARG VAL VAL
SEQRES   2 K  206  VAL ASP ALA ARG HIS HIS MET LEU GLY ARG LEU ALA SER
SEQRES   3 K  206  ILE VAL ALA LYS GLU LEU LEU ASN GLY GLN ARG VAL VAL
SEQRES   4 K  206  VAL VAL ARG CYS GLU GLU ILE CYS MET SER GLY GLY LEU
SEQRES   5 K  206  VAL ARG GLN LYS MET LYS TYR LEU ARG PHE LEU ARG LYS
SEQRES   6 K  206  ARG MET ASN THR LYS PRO SER HIS GLY PRO ILE HIS PHE
SEQRES   7 K  206  ARG ALA PRO ALA LYS ILE LEU TRP ARG THR ILE ARG GLY
SEQRES   8 K  206  MET ILE PRO HIS LYS THR ALA ARG GLY GLU ALA ALA LEU
SEQRES   9 K  206  ALA ARG LEU LYS ALA TYR GLU GLY VAL PRO PRO PRO TYR
SEQRES  10 K  206  ASP ARG THR LYS ARG MET VAL ILE PRO ASP ALA LEU LYS
SEQRES  11 K  206  VAL LEU ARG LEU GLN PRO GLY HIS ARG TYR CYS LEU LEU
SEQRES  12 K  206  GLY GLN LEU SER LYS GLU VAL GLY TRP ASN TYR ALA ASP
SEQRES  13 K  206  THR ILE ARG GLU LEU GLU GLU LYS ARG LYS GLU LYS ALA
SEQRES  14 K  206  LYS VAL SER TYR ASP ARG ARG LYS GLN LEU ALA LYS LEU
SEQRES  15 K  206  ARG VAL LYS ALA GLU LYS ALA ALA GLU GLU LYS LEU GLY
SEQRES  16 K  206  THR GLN LEU GLU ILE LEU ALA PRO ILE LYS TYR
SEQRES   1 m   92  MET THR LYS ARG THR LYS LYS ALA GLY ILE VAL GLY LYS
SEQRES   2 m   92  TYR GLY THR ARG TYR GLY ALA SER LEU ARG LYS GLN ILE
SEQRES   3 m   92  LYS LYS MET GLU VAL SER GLN HIS SER LYS TYR PHE CYS
SEQRES   4 m   92  GLU PHE CYS GLY LYS PHE ALA VAL LYS ARG LYS ALA VAL
SEQRES   5 m   92  GLY ILE TRP GLY CYS LYS ASP CYS GLY LYS VAL LYS ALA
SEQRES   6 m   92  GLY GLY ALA TYR THR MET ASN THR ALA SER ALA VAL THR
SEQRES   7 m   92  VAL ARG SER THR ILE ARG ARG LEU ARG GLU GLN THR GLU
SEQRES   8 m   92  ALA
SEQRES   1 I  224  MET GLY ARG ARG PRO ALA ARG CYS TYR ARG GLN ILE LYS
SEQRES   2 I  224  ASN LYS PRO TYR PRO LYS SER ARG TYR CYS ARG GLY VAL
SEQRES   3 I  224  PRO ASP PRO LYS ILE ARG ILE TYR ASP VAL GLY MET LYS
SEQRES   4 I  224  LYS LYS GLY VAL ASP GLU PHE PRO TYR CYS VAL HIS LEU
SEQRES   5 I  224  VAL SER TRP GLU LYS GLU ASN VAL SER SER GLU ALA LEU
SEQRES   6 I  224  GLU ALA ALA ARG ILE ALA CYS ASN LYS TYR MET THR LYS
SEQRES   7 I  224  ASN ALA GLY LYS ASP ALA PHE HIS LEU ARG VAL ARG VAL
SEQRES   8 I  224  HIS PRO PHE HIS VAL LEU ARG ILE ASN LYS MET LEU SER
SEQRES   9 I  224  CYS ALA GLY ALA ASP ARG LEU GLN THR GLY MET ARG GLY
SEQRES  10 I  224  ALA PHE GLY LYS PRO GLN GLY THR CYS ALA ARG VAL ASP
SEQRES  11 I  224  ILE GLY GLN VAL LEU LEU SER VAL ARG CYS LYS GLU SER
SEQRES  12 I  224  ASN ALA LYS HIS ALA GLU GLU ALA LEU ARG ARG ALA LYS
SEQRES  13 I  224  PHE LYS PHE PRO GLY ARG GLN LYS ILE ILE HIS SER ARG
SEQRES  14 I  224  LYS TRP GLY PHE THR LYS PHE THR ARG GLU GLU TYR VAL
SEQRES  15 I  224  LYS LEU LYS ALA GLU GLY ARG ILE MET SER ASP GLY VAL
SEQRES  16 I  224  ASN ALA GLN LEU LEU GLY SER HIS GLY ARG LEU ALA LYS
SEQRES  17 I  224  ARG ALA PRO GLY LYS ALA PHE LEU ALA GLU THR ILE GLN
SEQRES  18 I  224  ALA SER ALA
HELIX    1   1 SER A    2  SER A    6  5                                   5
HELIX    2   2 GLU A   22  PHE A   27  1                                   6
HELIX    3   3 VAL A   73  ASP A   82  1                                  10
HELIX    4   4 SER A   88  LYS A   90  5                                   3
HELIX    5   5 LYS A   91  LEU A   98  1                                   8
HELIX    6   6 ALA A  111  GLY A  124  1                                  14
HELIX    7   7 HIS A  139  THR A  150  1                                  12
HELIX    8   8 SER A  172  SER A  191  1                                  20
HELIX    9   9 ILE B    5  LYS B   10  1                                   6
HELIX   10  10 ARG B  105  VAL B  107  5                                   3
HELIX   11  11 LYS B  181  VAL B  191  1                                  11
HELIX   12  12 ARG E   34  GLY E   44  1                                  11
HELIX   13  13 ARG E   74  VAL E   88  1                                  15
HELIX   14  14 ARG E  135  GLY E  137  5                                   3
HELIX   15  15 TYR E  138  ARG E  143  1                                   6
HELIX   16  16 THR E  157  LYS E  168  1                                  12
HELIX   17  17 THR F   62  LYS F   85  1                                  24
HELIX   18  18 ASN F  115  GLU F  119  5                                   5
HELIX   19  19 ASP F  149  CYS F  164  1                                  16
HELIX   20  20 LYS H   64  VAL H   69  1                                   6
HELIX   21  21 ASN H   74  ALA H   85  1                                  12
HELIX   22  22 GLU H   98  ALA H  113  1                                  16
HELIX   23  23 GLY H  131  GLN H  141  1                                  11
HELIX   24  24 ILE H  156  ARG H  167  1                                  12
HELIX   25  25 GLY H  178  VAL H  186  1                                   9
HELIX   26  26 LYS H  204  LYS H  215  1                                  12
HELIX   27  27 MET H  234  MET H  257  1                                  24
HELIX   28  28 LYS M  123  TRP M  129  1                                   7
HELIX   29  29 TRP M  129  SER M  134  1                                   6
HELIX   30  30 ALA P    3  ARG P   13  1                                  11
HELIX   31  31 SER P   16  GLN P   33  1                                  18
HELIX   32  32 ARG P   44  ARG P   49  1                                   6
HELIX   33  33 LYS P   83  GLN P   87  5                                   5
HELIX   34  34 ASN P   97  LEU P  110  1                                  14
HELIX   35  35 HIS P  139  ASN P  144  1                                   6
HELIX   36  36 ILE P  148  CYS P  152  5                                   5
HELIX   37  37 LYS P  153  LYS P  157  5                                   5
HELIX   38  38 THR P  165  TYR P  171  1                                   7
HELIX   39  39 THR P  180  ALA P  184  5                                   5
HELIX   40  40 LYS O   47  PHE O   53  1                                   7
HELIX   41  41 VAL O   75  ARG O   77  5                                   3
HELIX   42  42 LEU O  107  LEU O  112  1                                   6
HELIX   43  43 LEU O  124  LYS O  127  5                                   4
HELIX   44  44 ILE R    3  ARG R   10  1                                   8
HELIX   45  45 ASP R   23  ARG R   38  1                                  16
HELIX   46  46 SER R   42  MET R   54  1                                  13
HELIX   47  47 MET R   64  ASN R   69  1                                   6
HELIX   48  48 THR R  106  ASN R  115  1                                  10
HELIX   49  49 PHE R  123  ALA R  130  1                                   8
HELIX   50  50 GLY Q    6  GLN Q   11  1                                   6
HELIX   51  51 HIS Q   14  VAL Q   22  1                                   9
HELIX   52  52 PHE Q   24  GLY Q   30  1                                   7
HELIX   53  53 ASP Q   33  ASN Q   42  1                                  10
HELIX   54  54 GLU Q   83  GLY Q   88  5                                   6
HELIX   55  55 ASN Q   95  THR Q  112  1                                  18
HELIX   56  56 ASN Q  157  ASP Q  168  1                                  12
HELIX   57  57 GLY Q  182  ASP Q  186  5                                   5
HELIX   58  58 VAL Q  204  SER Q  210  1                                   7
HELIX   59  59 GLN Q  220  ASP Q  232  1                                  13
HELIX   60  60 ASP Q  250  THR Q  257  1                                   8
HELIX   61  61 ALA Q  262  LYS Q  278  1                                  17
HELIX   62  62 ASP Q  295  ASP Q  302  1                                   8
HELIX   63  63 LEU T    4  LYS T   16  1                                  13
HELIX   64  64 GLU T   28  ALA T   35  1                                   8
HELIX   65  65 SER T   37  ASP T   47  1                                  11
HELIX   66  66 SER T   59  ALA T   69  1                                  11
HELIX   67  67 THR T   91  LYS T  113  1                                  23
HELIX   68  68 ASP T  116  GLY T  129  1                                  14
HELIX   69  69 LEU T  138  ALA T  182  1                                  45
HELIX   70  70 ALA T  182  CYS T  189  1                                   8
HELIX   71  71 THR U   11  ALA U   16  1                                   6
HELIX   72  72 PRO U   18  LYS U   22  5                                   5
HELIX   73  73 LEU U   27  ARG U   32  1                                   6
HELIX   74  74 HIS U   54  HIS U   58  5                                   5
HELIX   75  75 ARG U   92  GLU U   94  5                                   3
HELIX   76  76 SER U   99  ALA U  119  1                                  21
HELIX   77  77 LYS U  129  GLY U  134  1                                   6
HELIX   78  78 VAL U  141  VAL U  149  1                                   9
HELIX   79  79 ASP U  155  TYR U  164  1                                  10
HELIX   80  80 HIS V   25  ILE V   36  1                                  12
HELIX   81  81 LEU V   41  HIS V   54  1                                  14
HELIX   82  82 PRO V   85  GLY V  107  1                                  23
HELIX   83  83 LYS V  154  LYS V  159  1                                   6
HELIX   84  84 SER X   33  HIS X   43  1                                  11
HELIX   85  85 THR X   79  ASN X   90  1                                  12
HELIX   86  86 LYS X  102  ASP X  114  1                                  13
HELIX   87  87 ASP X  141  ASN X  147  1                                   7
HELIX   88  88 LYS X  148  GLY X  150  5                                   3
HELIX   89  89 ASN Z   35  ARG Z   45  1                                  11
HELIX   90  90 LYS Z   47  LEU Z   51  5                                   5
HELIX   91  91 SER Y   10  ALA Y   21  1                                  12
HELIX   92  92 PRO Y   22  LEU Y   29  1                                   8
HELIX   93  93 SER Y   35  HIS Y   40  1                                   6
HELIX   94  94 HIS Y   99  SER Y  101  5                                   3
HELIX   95  95 LYS Y  112  ALA Y  130  1                                  19
HELIX   96  96 LYS b   94  VAL b  107  1                                  14
HELIX   97  97 TYR b  111  THR b  117  1                                   7
HELIX   98  98 LYS b  118  TYR b  128  1                                  11
HELIX   99  99 LYS d   38  HIS d   49  1                                  12
HELIX  100 100 ASN d   50  GLU d   57  1                                   8
HELIX  101 101 LYS f    9  GLY f   11  5                                   3
HELIX  102 102 GLU f   12  LYS f   23  1                                  12
HELIX  103 103 GLY f   30  SER f   40  1                                  11
HELIX  104 104 PRO f   53  ALA f   67  1                                  15
HELIX  105 105 ASP f   80  GLY f   86  1                                   7
HELIX  106 106 ASP f  103  THR f  108  1                                   6
HELIX  107 107 LEU g   24  CYS g   31  1                                   8
HELIX  108 108 LYS g   36  GLY g   53  1                                  18
HELIX  109 109 ASP g   60  THR g   69  1                                  10
HELIX  110 110 ILE g  106  VAL g  118  1                                  13
HELIX  111 111 MET h    1  VAL h   11  1                                  11
HELIX  112 112 HIS h   22  TYR h   26  5                                   5
HELIX  113 113 SER h   41  LYS h   46  1                                   6
HELIX  114 114 ASN h   55  GLY h   59  5                                   5
HELIX  115 115 ASN h   79  ASN h   90  1                                  12
HELIX  116 116 SER h  102  ASP h  117  1                                  16
HELIX  117 117 THR h  121  GLU h  131  1                                  11
HELIX  118 118 GLY l    4  ARG l   11  1                                   8
HELIX  119 119 GLN l   30  SER l   32  5                                   3
HELIX  120 120 VAL l   51  GLY l   60  1                                  10
HELIX  121 121 ARG l   65  LYS l   75  1                                  11
HELIX  122 122 LYS n    3  ARG n   16  1                                  14
HELIX  123 123 ASP n   49  LEU n   56  1                                   8
HELIX  124 124 THR o    6  ASN o   20  1                                  15
HELIX  125 125 PRO o   24  MET o   29  5                                   6
HELIX  126 126 ALA r   37  LYS r   46  1                                  10
HELIX  127 127 LYS q    4  MET q   20  1                                  17
HELIX  128 128 UNK y    1  UNK y   17  1                                  17
HELIX  129 129 UNK z    3  UNK z   11  1                                   9
HELIX  130 130 MET G    1  LEU G    9  1                                   9
HELIX  131 131 LYS G   12  TRP G   26  1                                  15
HELIX  132 132 LYS G   29  LEU G   36  1                                   8
HELIX  133 133 ASP G   55  LYS G   65  1                                  11
HELIX  134 134 PRO G   66  ILE G   75  1                                  10
HELIX  135 135 TYR G  146  THR G  170  1                                  25
HELIX  136 136 LEU G  173  VAL G  183  1                                  11
HELIX  137 137 LEU G  198  GLY G  211  1                                  14
HELIX  138 138 UNK L   29  UNK L   51  1                                  23
HELIX  139 139 UNK L   63  UNK L   81  1                                  19
HELIX  140 140 UNK L   94  UNK L  100  1                                   7
HELIX  141 141 UNK L  103  UNK L  108  1                                   6
HELIX  142 142 UNK L  130  UNK L  145  1                                  16
HELIX  143 143 UNK L  157  UNK L  169  1                                  13
HELIX  144 144 UNK L  170  UNK L  191  1                                  22
HELIX  145 145 LYS N   67  ASP N   79  1                                  13
HELIX  146 146 VAL N   80  SER N   88  1                                   9
HELIX  147 147 LYS N   92  SER N  101  1                                  10
HELIX  148 148 PHE N  105  ALA N  134  1                                  30
HELIX  149 149 ASN S   35  LEU S   50  1                                  16
HELIX  150 150 THR S  100  SER S  114  1                                  15
HELIX  151 151 ASP S  139  LYS S  150  1                                  12
HELIX  152 152 PRO S  160  LYS S  164  5                                   5
HELIX  153 153 ILE W   38  GLY W   53  1                                  16
HELIX  154 154 TYR W   84  LYS W   94  1                                  11
HELIX  155 155 LYS a   65  GLY a   97  1                                  33
HELIX  156 156 MET i    1  ARG i   10  1                                  10
HELIX  157 157 LEU i   82  LYS i  101  1                                  20
HELIX  158 158 LYS j   42  TRP j   47  1                                   6
HELIX  159 159 VAL k   43  LEU k   63  1                                  21
HELIX  160 160 GLY k   67  LYS k   77  1                                  11
HELIX  161 161 GLY k   81  GLU k   91  1                                  11
HELIX  162 162 VAL k   96  ASP k  109  1                                  14
HELIX  163 163 UNK x   11  UNK x   19  1                                   9
HELIX  164 164 ALA J   24  ALA J   29  1                                   6
HELIX  165 165 LYS J   41  ALA J   51  1                                  11
HELIX  166 166 ALA J   78  LYS J   87  1                                  10
HELIX  167 167 SER J  106  ARG J  118  1                                  13
HELIX  168 168 GLU J  125  CYS J  137  1                                  13
HELIX  169 169 VAL t    6  GLY t   19  1                                  14
HELIX  170 170 THR t   23  GLY t   35  1                                  13
HELIX  171 171 ALA t   40  GLU t   51  1                                  12
HELIX  172 172 SER t   54  LEU t   60  1                                   7
HELIX  173 173 VAL u    6  GLY u   19  1                                  14
HELIX  174 174 THR u   23  GLY u   35  1                                  13
HELIX  175 175 ALA u   40  GLU u   51  1                                  12
HELIX  176 176 SER u   54  LEU u   60  1                                   7
HELIX  177 177 MET v    1  GLY v   14  1                                  14
HELIX  178 178 ASP v   22  GLY v   31  1                                  10
HELIX  179 179 ASP v   35  LYS v   47  1                                  13
HELIX  180 180 ASP v   50  ALA v   57  1                                   8
HELIX  181 181 MET w    1  GLY w   14  1                                  14
HELIX  182 182 ASP w   22  GLY w   31  1                                  10
HELIX  183 183 ASP w   35  LYS w   47  1                                  13
HELIX  184 184 ASP w   50  ALA w   57  1                                   8
HELIX  185 185 LYS c    7  ASN c   13  1                                   7
HELIX  186 186 SER c   15  SER c   40  1                                  26
HELIX  187 187 SER c   41  LYS c   75  1                                  35
HELIX  188 188 LEU c   82  THR c   89  1                                   8
HELIX  189 189 ARG c   90  LEU c   96  1                                   7
HELIX  190 190 GLU c  100  LEU c  105  1                                   6
HELIX  191 191 ARG c  118  LYS c  123  1                                   6
HELIX  192 192 MET e    1  LYS e   36  1                                  36
HELIX  193 193 ILE e   37  ASP e   61  1                                  25
HELIX  194 194 VAL e   65  ALA e   71  1                                   7
HELIX  195 195 HIS e   98  LEU e  108  1                                  11
HELIX  196 196 ASN e  122  ARG e  130  1                                   9
HELIX  197 197 ARG e  131  TYR e  135  5                                   5
HELIX  198 198 ASN e  142  GLY e  154  1                                  13
HELIX  199 199 ASN e  167  GLU e  172  1                                   6
HELIX  200 200 CYS e  182  VAL e  193  1                                  12
HELIX  201 201 ARG e  232  ARG e  241  1                                  10
HELIX  202 202 VAL s   12  TYR s   25  1                                  14
HELIX  203 203 GLY s   37  SER s   52  1                                  16
HELIX  204 204 ARG s   63  ASP s   71  1                                   9
HELIX  205 205 ASP s   97  TYR s  108  1                                  12
HELIX  206 206 THR s  138  ASN s  145  1                                   8
HELIX  207 207 GLY s  171  GLY s  182  1                                  12
HELIX  208 208 SER s  203  ASP s  208  1                                   6
HELIX  209 209 GLU s  211  SER s  233  1                                  23
HELIX  210 210 ALA s  239  VAL s  256  1                                  18
HELIX  211 211 GLU C  112  ARG C  117  1                                   6
HELIX  212 212 ASP C  138  ALA C  157  1                                  20
HELIX  213 213 ILE C  168  MET C  171  5                                   4
HELIX  214 214 THR C  190  GLU C  203  1                                  14
HELIX  215 215 PRO C  207  VAL C  211  5                                   5
HELIX  216 216 GLY C  231  GLY C  237  1                                   7
HELIX  217 217 GLN C  375  TYR C  384  1                                  10
HELIX  218 218 ALA D   29  ALA D   34  5                                   6
HELIX  219 219 ARG D   37  ASN D   51  1                                  15
HELIX  220 220 ASN D  120  THR D  135  1                                  16
HELIX  221 221 VAL D  137  GLY D  145  1                                   9
HELIX  222 222 LYS D  167  GLY D  179  1                                  13
HELIX  223 223 ALA D  180  LYS D  186  1                                   7
HELIX  224 224 GLY D  196  MET D  200  5                                   5
HELIX  225 225 VAL D  223  ASN D  228  1                                   6
HELIX  226 226 GLU D  238  LEU D  240  5                                   3
HELIX  227 227 ASN D  241  ALA D  246  1                                   6
HELIX  228 228 PRO D  247  HIS D  250  5                                   4
HELIX  229 229 GLU D  259  LYS D  263  1                                   5
HELIX  230 230 VAL D  306  VAL D  314  1                                   9
HELIX  231 231 ARG D  317  ASN D  326  1                                  10
HELIX  232 232 LYS D  332  ARG D  341  1                                  10
HELIX  233 233 ALA D  350  ARG D  355  1                                   6
HELIX  234 234 GLU D  357  THR D  384  1                                  28
HELIX  235 235 SER D  389  THR D  404  1                                  16
HELIX  236 236 MET K   20  ASN K   34  1                                  15
HELIX  237 237 CYS K   43  GLU K   45  5                                   3
HELIX  238 238 GLY K   51  ARG K   66  1                                  16
HELIX  239 239 ALA K   80  ILE K   93  1                                  14
HELIX  240 240 THR K   97  ALA K  105  1                                   9
HELIX  241 241 LEU K  143  SER K  147  1                                   5
HELIX  242 242 LYS K  148  VAL K  150  5                                   3
HELIX  243 243 ASN K  153  GLU K  192  1                                  40
HELIX  244 244 ILE K  200  LYS K  205  1                                   6
HELIX  245 245 ILE m   10  TYR m   14  5                                   5
HELIX  246 246 GLY m   19  SER m   35  1                                  17
HELIX  247 247 THR m   73  ALA m   92  1                                  20
HELIX  248 248 ALA I    6  GLN I   11  1                                   6
HELIX  249 249 SER I   62  GLY I   81  1                                  20
HELIX  250 250 LYS I  141  SER I  143  5                                   3
HELIX  251 251 ASN I  144  LYS I  156  1                                  13
HELIX  252 252 PHE I  157  PHE I  159  5                                   3
HELIX  253 253 LYS I  175  LEU I  184  1                                  10
SHEET    1   A 7 ASP A  11  ILE A  13  0
SHEET    2   A 7 VAL A 213  PHE A 216  1  O  PHE A 216   N  ALA A  12
SHEET    3   A 7 CYS A 202  VAL A 205 -1  N  VAL A 205   O  VAL A 213
SHEET    4   A 7 GLN A  34  TYR A  40 -1  N  LYS A  38   O  TYR A 204
SHEET    5   A 7 VAL A 161  VAL A 168 -1  O  VAL A 166   N  ILE A  35
SHEET    6   A 7 VAL A 154  PHE A 156 -1  N  LYS A 155   O  CYS A 163
SHEET    7   A 7 VAL A  52  LYS A  53 -1  N  LYS A  53   O  VAL A 154
SHEET    1   B 3 ASP A  85  GLU A  87  0
SHEET    2   B 3 LEU A  67  ALA A  70  1  N  ASP A  69   O  GLU A  87
SHEET    3   B 3 LYS A 104  HIS A 107  1  O  LYS A 104   N  GLY A  68
SHEET    1   C 4 LEU B  75  VAL B  77  0
SHEET    2   C 4 PRO B  57  THR B  62 -1  N  ALA B  59   O  PHE B  76
SHEET    3   C 4 LYS B  42  HIS B  50 -1  N  ILE B  49   O  LEU B  58
SHEET    4   C 4 PHE B  87  TYR B  89 -1  O  VAL B  88   N  GLY B  43
SHEET    1   D 6 VAL B 101  PRO B 103  0
SHEET    2   D 6 ARG B 163  ILE B 166 -1  O  ALA B 164   N  LEU B 102
SHEET    3   D 6 ALA B 111  CYS B 114 -1  N  CYS B 114   O  MET B 165
SHEET    4   D 6 ALA B 134  SER B 138 -1  O  ALA B 134   N  VAL B 113
SHEET    5   D 6 SER B 146  LYS B 149 -1  O  LYS B 149   N  ILE B 135
SHEET    6   D 6 LYS B 155  VAL B 158 -1  O  LYS B 156   N  ILE B 148
SHEET    1   E 2 THR B 224  VAL B 225  0
SHEET    2   E 2 LEU B 237  ILE B 238  1  O  LEU B 237   N  VAL B 225
SHEET    1   F 5 VAL E  48  SER E  50  0
SHEET    2   F 5 ALA E  68  ILE E  73 -1  O  TYR E  70   N  VAL E  48
SHEET    3   F 5 LYS E  15  SER E  24 -1  N  LEU E  19   O  ILE E  73
SHEET    4   F 5 ASP E 128  GLU E 134 -1  O  VAL E 132   N  LYS E  18
SHEET    5   F 5 PHE E 104  GLY E 107 -1  N  PHE E 106   O  PHE E 129
SHEET    1   G 3 GLU F   8  GLU F  11  0
SHEET    2   G 3 LYS F  53  ALA F  58 -1  O  LEU F  54   N  MET F  10
SHEET    3   G 3 LEU F  43  LEU F  48 -1  N  GLN F  46   O  GLN F  55
SHEET    1   H 3 THR F  17  ALA F  21  0
SHEET    2   H 3 VAL F  24  GLY F  29 -1  O  THR F  26   N  GLN F  19
SHEET    3   H 3 GLY F  32  ASN F  37 -1  O  ARG F  36   N  VAL F  25
SHEET    1   I 4 THR F 132  ARG F 135  0
SHEET    2   I 4 GLU F 142  GLY F 147 -1  O  VAL F 144   N  LEU F 134
SHEET    3   I 4 TYR F  87  VAL F  94 -1  N  MET F  91   O  LEU F 143
SHEET    4   I 4 GLY F 177  VAL F 180 -1  O  GLY F 177   N  VAL F  94
SHEET    1   J 3 ASN F 101  THR F 105  0
SHEET    2   J 3 ALA F 110  ARG F 114 -1  O  ARG F 114   N  ASN F 101
SHEET    3   J 3 ARG F 123  ASP F 126 -1  O  ARG F 123   N  ILE F 113
SHEET    1   K 4 VAL H 128  TYR H 130  0
SHEET    2   K 4 LEU H 194  THR H 198 -1  O  LEU H 196   N  LYS H 129
SHEET    3   K 4 ALA H 144  ALA H 150 -1  N  GLN H 145   O  THR H 197
SHEET    4   K 4 TYR H 173  VAL H 176  1  O  CYS H 174   N  ILE H 149
SHEET    1   L 5 ARG M  15  MET M  16  0
SHEET    2   L 5 TRP M  88  ARG M  89 -1  O  ARG M  89   N  ARG M  15
SHEET    3   L 5 PHE M  95  PHE M  98 -1  O  MET M  96   N  TRP M  88
SHEET    4   L 5 ILE Z  21  ILE Z  24  1  O  ILE Z  24   N  TYR M  97
SHEET    5   L 5 VAL Z  30  PHE Z  33 -1  O  PHE Z  33   N  ILE Z  21
SHEET    1   M 2 LEU M  20  PRO M  21  0
SHEET    2   M 2 SER M  54  ALA M  55 -1  O  ALA M  55   N  LEU M  20
SHEET    1   N 6 THR M  25  CYS M  28  0
SHEET    2   N 6 LEU M  37  VAL M  42 -1  O  LEU M  37   N  VAL M  26
SHEET    3   N 6 MET M  60  VAL M  65 -1  O  THR M  64   N  TYR M  38
SHEET    4   N 6 VAL M  76  ARG M  83 -1  O  ALA M  79   N  VAL M  61
SHEET    5   N 6 ALA M 102  ILE M 105 -1  O  VAL M 104   N  VAL M  80
SHEET    6   N 6 THR M  25  CYS M  28  1  N  ASN M  27   O  GLY M 103
SHEET    1   O 2 ILE M 121  GLY M 122  0
SHEET    2   O 2 ILE M 139  VAL M 140  1  O  VAL M 140   N  ILE M 121
SHEET    1   P 4 ILE P  36  LEU P  39  0
SHEET    2   P 4 TYR P  59  ARG P  67 -1  O  ARG P  63   N  VAL P  37
SHEET    3   P 4 TYR P 127  VAL P 135 -1  O  LYS P 128   N  VAL P  66
SHEET    4   P 4 ARG P 114  GLU P 123 -1  N  ARG P 114   O  VAL P 135
SHEET    1   Q 3 ARG O  42  ASP O  46  0
SHEET    2   Q 3 ALA O  86  ALA O  90  1  O  ALA O  88   N  ILE O  43
SHEET    3   Q 3 LYS O 105  VAL O 106  1  O  LYS O 105   N  GLY O  89
SHEET    1   R 3 PRO O  71  VAL O  73  0
SHEET    2   R 3 GLN O 100  TYR O 103  1  O  GLY O 102   N  ALA O  72
SHEET    3   R 3 LYS O 121  ALA O 122  1  O  LYS O 121   N  PHE O 101
SHEET    1   S 4 PRO R  61  SER R  63  0
SHEET    2   S 4 ILE R  79  THR R  87  1  O  THR R  87   N  LEU R  62
SHEET    3   S 4 MET R  98  ARG R 104  1  O  THR R 101   N  ALA R  80
SHEET    4   S 4 GLY R 118  THR R 122  1  O  LEU R 121   N  VAL R 100
SHEET    1   T 3 PRO R  61  SER R  63  0
SHEET    2   T 3 ILE R  79  THR R  87  1  O  THR R  87   N  LEU R  62
SHEET    3   T 3 THR R 136  LEU R 138  1  O  ILE R 137   N  VAL R  81
SHEET    1   U 4 GLY Q  72  TYR Q  80  0
SHEET    2   U 4 THR Q  62  THR Q  69 -1  N  ILE Q  65   O  MET Q  76
SHEET    3   U 4 LYS Q  47  ASN Q  49 -1  N  LYS Q  47   O  VAL Q  66
SHEET    4   U 4 LEU Q 145  ASP Q 147  1  O  LEU Q 145   N  TYR Q  48
SHEET    1   V 2 VAL T  22  LEU T  24  0
SHEET    2   V 2 ILE T  50  ARG T  52 -1  O  ILE T  51   N  TRP T  23
SHEET    1   W 5 LYS U  86  VAL U  91  0
SHEET    2   W 5 ILE U  72  ASN U  77 -1  N  VAL U  74   O  ILE U  89
SHEET    3   W 5 ARG U  60  VAL U  67 -1  N  ARG U  63   O  GLU U  75
SHEET    4   W 5 HIS U  39  VAL U  42 -1  N  VAL U  40   O  GLY U  62
SHEET    5   W 5 VAL U  96  PRO U  98 -1  O  GLN U  97   N  ASP U  41
SHEET    1   X 3 SER V  14  ARG V  23  0
SHEET    2   X 3 PRO V 144  SER V 152 -1  O  LEU V 151   N  SER V  15
SHEET    3   X 3 TYR V 114  GLN V 122 -1  N  HIS V 117   O  ILE V 150
SHEET    1   Y 2 ILE V  58  PRO V  59  0
SHEET    2   Y 2 GLY V  82  ARG V  83 -1  O  ARG V  83   N  ILE V  58
SHEET    1   Z 2 ARG V 129  ARG V 132  0
SHEET    2   Z 2 ARG V 136  PRO V 139 -1  O  ARG V 136   N  ARG V 132
SHEET    1  AA 4 LEU X  73  PRO X  76  0
SHEET    2  AA 4 THR X  91  VAL X  96 -1  O  ILE X  95   N  TYR X  75
SHEET    3  AA 4 LYS X 130  LEU X 136 -1  O  VAL X 134   N  LEU X  92
SHEET    4  AA 4 ALA X 117  ILE X 124 -1  N  LEU X 123   O  LYS X 131
SHEET    1  AB 2 GLU Z   6  LEU Z   7  0
SHEET    2  AB 2 LYS Z  14  ILE Z  15 -1  O  ILE Z  15   N  GLU Z   6
SHEET    1  AC 6 SER Y  46  PRO Y  48  0
SHEET    2  AC 6 SER Y  31  LEU Y  34 -1  N  ALA Y  32   O  ILE Y  47
SHEET    3  AC 6 VAL Y 103  LYS Y 107  1  O  VAL Y 105   N  ALA Y  33
SHEET    4  AC 6 GLU Y  54  VAL Y  57 -1  N  GLN Y  56   O  VAL Y 104
SHEET    5  AC 6 GLU Y  66  TYR Y  73 -1  O  GLY Y  67   N  VAL Y  55
SHEET    6  AC 6 VAL Y  78  VAL Y  81 -1  O  HIS Y  80   N  GLN Y  71
SHEET    1  AD 2 THR Y  85  GLU Y  87  0
SHEET    2  AD 2 THR Y  93  ASN Y  95 -1  O  VAL Y  94   N  ARG Y  86
SHEET    1  AE 2 THR b  74  THR b  75  0
SHEET    2  AE 2 LYS b  89  SER b  90 -1  O  SER b  90   N  THR b  74
SHEET    1  AF 4 LYS f  26  LEU f  29  0
SHEET    2  AF 4 CYS f  93  LEU f  97 -1  O  LEU f  97   N  LYS f  26
SHEET    3  AF 4 LEU f  45  LEU f  48 -1  N  LEU f  45   O  ILE f  96
SHEET    4  AF 4 VAL f  71  HIS f  72  1  O  HIS f  72   N  LEU f  48
SHEET    1  AG 3 THR g  17  ASN g  23  0
SHEET    2  AG 3 ARG g  78  LYS g  86 -1  O  VAL g  81   N  TYR g  20
SHEET    3  AG 3 GLU g  91  GLU g  96 -1  O  ALA g  93   N  SER g  84
SHEET    1  AH 2 LYS h  73  VAL h  77  0
SHEET    2  AH 2 TYR h  93  ILE h  97  1  O  GLU h  96   N  VAL h  77
SHEET    1  AI 3 HIS l  16  LEU l  18  0
SHEET    2  AI 3 ARG l  25  HIS l  28 -1  O  PHE l  27   N  THR l  17
SHEET    3  AI 3 THR l  33  CYS l  34 -1  O  THR l  33   N  HIS l  28
SHEET    1  AJ 2 VAL n  23  ARG n  24  0
SHEET    2  AJ 2 LYS n  35  VAL n  36 -1  O  LYS n  35   N  ARG n  24
SHEET    1  AK 3 THR r   7  THR r  10  0
SHEET    2  AK 3 THR r  21  GLN r  27 -1  O  HIS r  23   N  LYS r   8
SHEET    3  AK 3 LEU r  70  CYS r  74 -1  O  GLN r  73   N  LYS r  24
SHEET    1  AL 2 LYS r  66  LYS r  67  0
SHEET    2  AL 2 ARG r  87  CYS r  88 -1  O  CYS r  88   N  LYS r  66
SHEET    1  AM 3 ARG G  92  VAL G  93  0
SHEET    2  AM 3 LEU G  81  ILE G  82 -1  N  LEU G  81   O  VAL G  93
SHEET    3  AM 3 ILE G 126  ALA G 127 -1  O  ILE G 126   N  ILE G  82
SHEET    1  AN 3 PHE G  95  GLN G  98  0
SHEET    2  AN 3 LEU G 104  ILE G 106 -1  O  LEU G 105   N  LYS G  97
SHEET    3  AN 3 ARG G 118  VAL G 120 -1  O  VAL G 120   N  LEU G 104
SHEET    1  AO 5 MET N  43  ASN N  49  0
SHEET    2  AO 5 ARG N  35  ALA N  40 -1  N  VAL N  38   O  CYS N  46
SHEET    3  AO 5 LEU N  24  VAL N  30 -1  N  VAL N  26   O  ASP N  39
SHEET    4  AO 5 ARG N  11  LEU N  14 -1  N  ALA N  13   O  VAL N  25
SHEET    5  AO 5 SER N  54  LYS N  59 -1  O  SER N  54   N  LEU N  14
SHEET    1  AP 3 LEU S  31  ALA S  33  0
SHEET    2  AP 3 HIS S   7  GLY S  13 -1  N  TYR S   9   O  LEU S  31
SHEET    3  AP 3 ILE S  60  ASN S  64 -1  O  ASN S  64   N  GLN S  10
SHEET    1  AQ 3 TYR S  89  GLU S  95  0
SHEET    2  AQ 3 GLY S  78  GLN S  84 -1  N  ILE S  79   O  LYS S  94
SHEET    3  AQ 3 ILE S 125  ALA S 129 -1  O  ALA S 129   N  GLY S  78
SHEET    1  AR 4 VAL W  63  ARG W  67  0
SHEET    2  AR 4 VAL W  72  SER W  76 -1  O  THR W  73   N  THR W  66
SHEET    3  AR 4 LYS W  18  PHE W  23 -1  N  VAL W  21   O  VAL W  74
SHEET    4  AR 4 TYR W 114  ARG W 117 -1  O  GLU W 115   N  SER W  20
SHEET    1  AS 4 GLY j  15  LYS j  21  0
SHEET    2  AS 4 THR j  31  ILE j  36 -1  O  GLN j  35   N  THR j  16
SHEET    3  AS 4 VAL j  85  LYS j  88 -1  O  VAL j  85   N  LEU j  34
SHEET    4  AS 4 LYS j  74  PRO j  78 -1  N  ARG j  77   O  ARG j  86
SHEET    1  AT 2 ALA j  54  TYR j  55  0
SHEET    2  AT 2 ILE j  71  TRP j  72 -1  O  ILE j  71   N  TYR j  55
SHEET    1  AU 2 MET p  18  ILE p  19  0
SHEET    2  AU 2 ARG p  46  PRO p  47 -1  O  ARG p  46   N  ILE p  19
SHEET    1  AV 3 VAL J  13  VAL J  17  0
SHEET    2  AV 3 VAL J  59  GLN J  66 -1  O  VAL J  61   N  VAL J  15
SHEET    3  AV 3 GLN J  69  SER J  73 -1  O  GLN J  69   N  GLN J  66
SHEET    1  AW 5 PHE e 207  LYS e 208  0
SHEET    2  AW 5 ASN e 115  LEU e 119 -1  N  GLY e 116   O  PHE e 207
SHEET    3  AW 5 LEU e  86  VAL e  89 -1  N  LEU e  86   O  LEU e 119
SHEET    4  AW 5 THR e 137  GLY e 139 -1  O  THR e 137   N  VAL e  89
SHEET    5  AW 5 GLY e 230  ASN e 231  1  O  GLY e 230   N  TYR e 138
SHEET    1  AX 5 VAL s  54  LEU s  55  0
SHEET    2  AX 5 VAL s  89  THR s  94 -1  O  LEU s  91   N  LEU s  55
SHEET    3  AX 5 LYS s  27  VAL s  32 -1  N  LEU s  29   O  ILE s  92
SHEET    4  AX 5 VAL s 191  ASP s 197 -1  O  TYR s 196   N  VAL s  28
SHEET    5  AX 5 SER s 200  PHE s 202 -1  O  PHE s 202   N  VAL s 195
SHEET    1  AY 2 VAL s 110  ALA s 112  0
SHEET    2  AY 2 PHE s 186  TYR s 188 -1  O  TYR s 188   N  VAL s 110
SHEET    1  AZ 2 VAL s 124  VAL s 126  0
SHEET    2  AZ 2 VAL s 161  ILE s 164 -1  O  VAL s 161   N  VAL s 126
SHEET    1  BA 3 GLY s 129  ASN s 130  0
SHEET    2  BA 3 THR s 154  ILE s 157 -1  O  ILE s 157   N  GLY s 129
SHEET    3  BA 3 THR s 148  ASN s 151 -1  N  LYS s 149   O  GLU s 156
SHEET    1  BB 7 HIS C 277  LYS C 284  0
SHEET    2  BB 7 MET C 217  VAL C 223 -1  N  ILE C 220   O  GLU C 280
SHEET    3  BB 7 VAL C 339  GLN C 344 -1  O  ARG C 343   N  ASP C 219
SHEET    4  BB 7 ALA C  45  ARG C  58 -1  N  PHE C  46   O  LEU C 342
SHEET    5  BB 7 THR C  72  GLU C  80 -1  O  VAL C  76   N  THR C  54
SHEET    6  BB 7 ASP C 324  LYS C 329 -1  O  ILE C 328   N  THR C  77
SHEET    7  BB 7 LYS C 287  LYS C 290 -1  N  LYS C 287   O  MET C 327
SHEET    1  BC 5 HIS C 277  LYS C 284  0
SHEET    2  BC 5 MET C 217  VAL C 223 -1  N  ILE C 220   O  GLU C 280
SHEET    3  BC 5 VAL C 339  GLN C 344 -1  O  ARG C 343   N  ASP C 219
SHEET    4  BC 5 ALA C  45  ARG C  58 -1  N  PHE C  46   O  LEU C 342
SHEET    5  BC 5 LEU C 360  ILE C 363 -1  O  PHE C 362   N  VAL C  57
SHEET    1  BD 4 ARG C 100  TRP C 106  0
SHEET    2  BD 4 LEU C  84  VAL C  93 -1  N  VAL C  93   O  ARG C 100
SHEET    3  BD 4 ILE C 159  THR C 166 -1  O  ILE C 159   N  TYR C  92
SHEET    4  BD 4 HIS C 180  GLN C 185 -1  O  ILE C 184   N  VAL C 162
SHEET    1  BE 2 GLY C 226  GLU C 230  0
SHEET    2  BE 2 GLY C 271  GLY C 274 -1  O  GLY C 271   N  GLU C 230
SHEET    1  BF 2 LEU D   8  VAL D   9  0
SHEET    2  BF 2 LEU D  26  ALA D  27 -1  O  LEU D  26   N  VAL D   9
SHEET    1  BG 4 LEU D 156  ILE D 158  0
SHEET    2  BG 4 VAL D 255  THR D 258  1  O  TRP D 257   N  ILE D 158
SHEET    3  BG 4 LEU D 212  TYR D 215  1  N  LEU D 212   O  ILE D 256
SHEET    4  BG 4 ASP D 233  ASN D 236  1  O  ALA D 235   N  TYR D 215
SHEET    1  BH 2 GLY D 192  ILE D 193  0
SHEET    2  BH 2 TYR D 205  ILE D 206 -1  O  ILE D 206   N  GLY D 192
SHEET    1  BI 3 VAL K  13  ASP K  15  0
SHEET    2  BI 3 VAL K  38  VAL K  41  1  O  VAL K  41   N  VAL K  14
SHEET    3  BI 3 LEU K 107  TYR K 110  1  O  LYS K 108   N  VAL K  40
SHEET    1  BJ 2 CYS K  47  SER K  49  0
SHEET    2  BJ 2 TYR K 140  LEU K 142 -1  O  CYS K 141   N  MET K  48
SHEET    1  BK 3 LYS m  48  ALA m  51  0
SHEET    2  BK 3 ILE m  54  GLY m  56 -1  O  GLY m  56   N  LYS m  48
SHEET    3  BK 3 VAL m  63  ALA m  65 -1  O  LYS m  64   N  TRP m  55
SHEET    1  BL 5 ASP I  35  GLY I  37  0
SHEET    2  BL 5 HIS I  86  VAL I  89 -1  O  LEU I  87   N  VAL I  36
SHEET    3  BL 5 VAL I 134  CYS I 140 -1  O  SER I 137   N  ARG I  88
SHEET    4  BL 5 TYR I  48  SER I  54 -1  N  TYR I  48   O  CYS I 140
SHEET    5  BL 5 GLN I 163  SER I 168 -1  O  ILE I 166   N  HIS I  51
SHEET    1  BM 3 GLU I  58  SER I  61  0
SHEET    2  BM 3 GLY I 124  VAL I 129 -1  O  VAL I 129   N  GLU I  58
SHEET    3  BM 3 HIS I  95  LEU I  97 -1  N  HIS I  95   O  CYS I 126
CISPEP   1 LYS B   73    GLU B   74          0       -16.89
CISPEP   2 TRP B  196    PRO B  197          0       -25.95
CISPEP   3 ALA B  252    THR B  253          0        14.16
CISPEP   4 TYR E   91    GLU E   92          0        -5.75
CISPEP   5 GLU E   92    LEU E   93          0       -14.10
CISPEP   6 LEU E   93    LEU E   94          0       -27.13
CISPEP   7 LYS F  183    GLY F  184          0         7.94
CISPEP   8 GLY F  184    THR F  185          0        16.22
CISPEP   9 PRO H   70    PRO H   71          0        12.99
CISPEP  10 GLU H  224    VAL H  225          0        -9.36
CISPEP  11 ARG M    4    GLY M    5          0       -22.98
CISPEP  12 ARG P  185    PRO P  186          0        28.02
CISPEP  13 LEU R  139    ARG R  140          0         7.04
CISPEP  14 GLY R  141    PRO R  142          0        19.71
CISPEP  15 GLU R  147    ALA R  148          0        29.21
CISPEP  16 PRO R  156    GLY R  157          0       -15.92
CISPEP  17 HIS R  160    SER R  161          0        27.85
CISPEP  18 GLY Q  122    ASN Q  123          0        29.12
CISPEP  19 VAL Q  124    GLU Q  125          0       -24.32
CISPEP  20 LYS Q  197    TYR Q  198          0        15.32
CISPEP  21 GLY Q  235    MET Q  236          0       -26.37
CISPEP  22 GLU Q  237    SER Q  238          0       -29.41
CISPEP  23 VAL Q  243    HIS Q  244          0       -23.22
CISPEP  24 ALA Q  246    ILE Q  247          0        -4.29
CISPEP  25 ALA Q  249    ASP Q  250          0        18.63
CISPEP  26 PRO Q  261    ALA Q  262          0       -27.72
CISPEP  27 LEU Q  285    ASN Q  286          0         6.10
CISPEP  28 SER Q  290    SER Q  291          0        -8.28
CISPEP  29 ALA Q  294    ASP Q  295          0        14.96
CISPEP  30 GLN T   71    LYS T   72          0       -29.98
CISPEP  31 ILE V   36    ARG V   37          0       -28.23
CISPEP  32 ARG V   69    THR V   70          0        20.66
CISPEP  33 LYS g    5    ARG g    6          0        -5.81
CISPEP  34 LYS h   13    ARG h   14          0       -16.21
CISPEP  35 TYR l   39    PRO l   40          0       -25.29
CISPEP  36 LYS l   88    ARG l   89          0        -2.02
CISPEP  37 ALA l   92    ALA l   93          0        13.34
CISPEP  38 ALA l   93    ASN l   94          0        -6.66
CISPEP  39 LYS r   97    LYS r   98          0       -17.71
CISPEP  40 UNK z    2    UNK z    3          0       -29.20
CISPEP  41 LYS G  171    ASN G  172          0       -19.65
CISPEP  42 VAL G  195    PRO G  196          0        -5.67
CISPEP  43 LYS G  213    PRO G  214          0         9.14
CISPEP  44 UNK L   81    UNK L   82          0        29.40
CISPEP  45 UNK L  103    UNK L  104          0       -27.70
CISPEP  46 ARG S  138    ASP S  139          0         9.07
CISPEP  47 LYS a    3    PHE a    4          0       -23.51
CISPEP  48 ASP a   57    SER a   58          0        -9.30
CISPEP  49 GLY i   41    PRO i   42          0        13.68
CISPEP  50 GLY i   80    VAL i   81          0        -6.58
CISPEP  51 TYR j   12    VAL j   13          0       -29.07
CISPEP  52 LYS j   60    THR j   61          0         8.07
CISPEP  53 LYS k   38    ARG k   39          0       -10.69
CISPEP  54 ARG k   39    VAL k   40          0       -20.33
CISPEP  55 VAL k   66    GLY k   67          0       -21.29
CISPEP  56 MET k   93    SER k   94          0         7.27
CISPEP  57 THR c   89    ARG c   90          0        13.16
CISPEP  58 ASN e  201    ASN e  202          0        -0.82
CISPEP  59 LEU e  204    TRP e  205          0        20.50
CISPEP  60 ALA s    8    GLU s    9          0       -15.00
CISPEP  61 MET C    1    SER C    2          0         9.53
CISPEP  62 HIS C    3    ARG C    4          0        28.87
CISPEP  63 ARG C    4    LYS C    5          0       -17.33
CISPEP  64 GLU C  301    PHE C  302          0       -25.70
CISPEP  65 PHE C  302    ASP C  303          0        22.65
CISPEP  66 ARG C  352    LEU C  353          0        22.82
CISPEP  67 ASP C  364    THR C  365          0         6.01
CISPEP  68 SER C  366    SER C  367          0        26.69
CISPEP  69 GLY C  372    ARG C  373          0        21.65
CISPEP  70 GLY D   16    ASP D   17          0       -19.80
CISPEP  71 ARG D   90    ALA D   91          0       -25.66
CISPEP  72 GLY D   94    ALA D   95          0        29.84
CISPEP  73 THR D  150    VAL D  151          0       -19.48
CISPEP  74 LEU D  154    PRO D  155          0       -28.26
CISPEP  75 THR D  345    LEU D  346          0        18.61
CISPEP  76 ASN K   68    THR K   69          0         3.39
CISPEP  77 GLY K   74    PRO K   75          0         1.52
CISPEP  78 TRP K  152    ASN K  153          0        26.71
CISPEP  79 LYS I   30    ILE I   31          0        -2.03
CISPEP  80 ARG I  116    GLY I  117          0         0.79
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1
ORIGX1      1.000000  0.000000  0.000000        0.00000
ORIGX2      0.000000  1.000000  0.000000        0.00000
ORIGX3      0.000000  0.000000  1.000000        0.00000
SCALE1      1.000000  0.000000  0.000000        0.00000
SCALE2      0.000000  1.000000  0.000000        0.00000
SCALE3      0.000000  0.000000  1.000000        0.00000
      
PROCHECK
Go to PROCHECK summary
 References