UniProt functional annotation for P02405

UniProt codes: P0CX27, P02405.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Subunit: Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). {ECO:0000269|PubMed:9559554}.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Ptm: In wild-type cells, 78% of L42 is monomethylated at both Lys- 40 and Lys-55, and 22% are a mixture of species with either residue monomethylated.
Mass spectrometry: Mass=12100.729; Method=Electrospray; Range=2- 106; Note=Monoisotopic mass with 2 methylation modifications.; Evidence={ECO:0000269|PubMed:11983894};
Mass spectrometry: Mass=12100.71; Method=Electrospray; Range=2- 106; Note=Monoisotopic mass with N6-methyl-Lys-40 and N6-methyl- Lys-55.; Evidence={ECO:0000269|PubMed:18957409};
Mass spectrometry: Mass=12108.0; Method=Electrospray; Range=2-106; Note=With N6-methyl-Lys-40 and N6-methyl-Lys-55.; Evidence={ECO:0000269|PubMed:18957409};
Miscellaneous: Present with 13600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Miscellaneous: There are 2 genes for L42 in yeast.
Similarity: Belongs to the ribosomal protein L44e family. {ECO:0000305}.
Sequence caution: Sequence=CAA96049.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.