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PDBsum entry 3iyn

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Virus PDB id
3iyn
Jmol
Contents
Protein chains
(+ 6 more) 915 a.a.
455 a.a.
284 a.a.
176 a.a.
128 a.a.
91 a.a.
86 a.a.
84 a.a.
HEADER    VIRUS                                   09-MAR-10   3IYN
TITLE     3.6-ANGSTROM CRYOEM STRUCTURE OF HUMAN ADENOVIRUS TYPE 5
COMPND    MOL_ID: 1;
COMPND   2 MOLECULE: HEXON PROTEIN;
COMPND   3 CHAIN: A, B, C, D, E, F, G, H, I, J, K, L;
COMPND   4 SYNONYM: LATE PROTEIN 2;
COMPND   5 MOL_ID: 2;
COMPND   6 MOLECULE: PENTON BASE PROTEIN;
COMPND   7 CHAIN: M;
COMPND   8 SYNONYM: VIRION COMPONENT III, PENTON BASE PROTEIN, PIII;
COMPND   9 MOL_ID: 3;
COMPND  10 MOLECULE: PERIPENTONAL HEXON-ASSOCIATED PROTEIN;
COMPND  11 CHAIN: N;
COMPND  12 SYNONYM: PROTEIN IIIA;
COMPND  13 MOL_ID: 4;
COMPND  14 MOLECULE: HEXON-ASSOCIATED PROTEIN;
COMPND  15 CHAIN: O, P;
COMPND  16 SYNONYM: PROTEIN VIII, PVIII;
COMPND  17 MOL_ID: 5;
COMPND  18 MOLECULE: HEXON-ASSOCIATED PROTEIN;
COMPND  19 CHAIN: Q, R, S, T;
COMPND  20 SYNONYM: PROTEIN IX, PIX
SOURCE    MOL_ID: 1;
SOURCE   2 ORGANISM_SCIENTIFIC: HUMAN ADENOVIRUS 5;
SOURCE   3 ORGANISM_COMMON: HADV-5;
SOURCE   4 ORGANISM_TAXID: 28285;
SOURCE   5 MOL_ID: 2;
SOURCE   6 ORGANISM_SCIENTIFIC: HUMAN ADENOVIRUS 5;
SOURCE   7 ORGANISM_COMMON: HADV-5;
SOURCE   8 ORGANISM_TAXID: 28285;
SOURCE   9 MOL_ID: 3;
SOURCE  10 ORGANISM_SCIENTIFIC: HUMAN ADENOVIRUS 5;
SOURCE  11 ORGANISM_COMMON: HADV-5;
SOURCE  12 ORGANISM_TAXID: 28285;
SOURCE  13 MOL_ID: 4;
SOURCE  14 ORGANISM_SCIENTIFIC: HUMAN ADENOVIRUS 5;
SOURCE  15 ORGANISM_COMMON: HADV-5;
SOURCE  16 ORGANISM_TAXID: 28285;
SOURCE  17 MOL_ID: 5;
SOURCE  18 ORGANISM_SCIENTIFIC: HUMAN ADENOVIRUS 5;
SOURCE  19 ORGANISM_COMMON: HADV-5;
SOURCE  20 ORGANISM_TAXID: 28285
KEYWDS    HUMAN ADENOVIRUS, CRYOEM, 3D RECONSTRUCTION, FULL-ATOM MODEL,
KEYWDS   2 INTERACTION NETWORK, CAPSID PROTEIN, HEXON PROTEIN, PENTON BASE
KEYWDS   3 PROTEIN, VIRION, HEXON-ASSOCIATED PROTEIN, ICOSAHEDRAL VIRUS, VIRUS
EXPDTA    ELECTRON MICROSCOPY
AUTHOR    H.LIU,L.JIN,S.B.S.KOH,I.ATANASOV,S.SCHEIN,L.WU,Z.H.ZHOU
REVDAT   1   08-SEP-10 3IYN    0
JRNL        AUTH   H.LIU,L.JIN,S.B.KOH,I.ATANASOV,S.SCHEIN,L.WU,Z.H.ZHOU
JRNL        TITL   ATOMIC STRUCTURE OF HUMAN ADENOVIRUS BY CRYO-EM REVEALS
JRNL        TITL 2 INTERACTIONS AMONG PROTEIN NETWORKS
JRNL        REF    SCIENCE                       V. 329  1038 2010
JRNL        REFN                   ISSN 0036-8075
JRNL        PMID   20798312
JRNL        DOI    10.1126/SCIENCE.1187433
REMARK   2
REMARK   2 RESOLUTION.    3.60 ANGSTROMS.
REMARK   3
REMARK   3 REFINEMENT.
REMARK   3   SOFTWARE PACKAGES      : IMIRS
REMARK   3   RECONSTRUCTION SCHEMA  : COMMON LINES
REMARK   3
REMARK   3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK   3   PDB ENTRY                    : NULL
REMARK   3   REFINEMENT SPACE             : NULL
REMARK   3   REFINEMENT PROTOCOL          : NULL
REMARK   3   REFINEMENT TARGET            : NULL
REMARK   3   OVERALL ANISOTROPIC B VALUE  : NULL
REMARK   3
REMARK   3 FITTING PROCEDURE : NULL
REMARK   3
REMARK   3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK   3   NOMINAL PIXEL SIZE (ANGSTROMS)    : 1.076
REMARK   3   ACTUAL PIXEL SIZE  (ANGSTROMS)    : 1.100
REMARK   3   EFFECTIVE RESOLUTION (ANGSTROMS)  : 3.600
REMARK   3   NUMBER OF PARTICLES               : 31815
REMARK   3   CTF CORRECTION METHOD             : EACH PARTICLE
REMARK   3
REMARK   3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: TMV IMAGES
REMARK   3
REMARK   3 OTHER DETAILS: THE PROGRAM CTFFIND WAS USED TO DETERMINE THE
REMARK   3  DEFOCUS VALUE AND ASTIGMATISM PARAMETERS FOR EACH MICROGRAPH. WE
REMARK   3  DETERMINED PARTICLE ORIENTATION, CENTRE PARAMETERS AND SUBSEQUENT
REMARK   3  3D RECONSTRUCTION WITH THE IMIRS PACKAGE, ENHANCED BY ICOS
REMARK   3  AHEDRAL SYMMETRY-ADAPTED FUNCTIONS FOR 3D RECONSTRUCTION. WE
REMARK   3  INCORPORATED ASTIGMATISM IN THE CTF CORRECTION IN BOTH
REMARK   3  ORIENTATION-CENTRE REFINEMENT AND 3D RECONSTRUCTION STEPS. THE
REMARK   3  IMIRS PROCEDURE WAS OPTIMIZED, AND THE DATA PROCESSING WAS
REMARK   3  COMPLETED WITHIN TWO MONTHS BY THREE PERSONAL COMPUTERS, EACH
REMARK   3  WITH EIGHT 2.33GHZ CPUS AND 16G MEMORY. (DETAILS ABOUT THE
REMARK   3  PARTICLE: 756 MICROGRAPHS THAT CLEARLY SHOWED SIGNALS UP TO 4
REMARK   3  ANGSTROM IN THEIR POWER SPECTRA WERE SELECTED. INDIVIDUAL
REMARK   3  PARTICLE IMAGES (1024 PIXEL BY 1024 PIXEL) WERE FIRST BOXED OUT
REMARK   3  AUTOMATICALLY BY THE AUTOBOX PROGRAM IN THE IMIRS PACKAGE,
REMARK   3  FOLLOWED BY MANUAL SCREENING WITH THE EMAN BOXER PROGRAM TO KEEP
REMARK   3  ONLY THE WELL-SEPARATED, CONTAMINATION-FREE AND INTACT 45000
REMARK   3  PARTICLES. THE PROGRAM CTFFIND WAS USED TO DETERMINE THE DEFOCUS
REMARK   3  VALUE AND ASTIGMATISM PARAMETERS FOR EACH MICROGRAPH.
REMARK   3  DETERMINATION OF PARTICLE ORIENTATION AND CENTRE, AND SUBSEQUENT
REMARK   3  3D RECONSTRUCTION WERE DONE WITH THE IMIRS PACKAGE, ENHANCED BY
REMARK   3  ICOSAHEDRAL SYMMETRY-ADAPTED FUNCTIONS. )
REMARK   4
REMARK   4 3IYN COMPLIES WITH FORMAT V. 3.20, 01-DEC-08
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 31-MAR-10.
REMARK 100 THE RCSB ID CODE IS RCSB160029.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245   RECONSTRUCTION METHOD          : SINGLE PARTICLE
REMARK 245   SPECIMEN TYPE                  : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245   SAMPLE TYPE                    : PARTICLE
REMARK 245   PARTICLE TYPE                  : ICOSAHEDRAL
REMARK 245   NAME OF SAMPLE                 : HUMAN ADENOVIRUS TYPE 5
REMARK 245   SAMPLE CONCENTRATION (MG ML-1) : NULL
REMARK 245   SAMPLE SUPPORT DETAILS         : THIS GRID PLUS SAMPLE WAS KEPT
REMARK 245                                    IN LIQUID NITROGEN BEFORE CRYOEM
REMARK 245                                    IMAGING.
REMARK 245   SAMPLE VITRIFICATION DETAILS   : VITRIFICATION CARRIED OUT IN A
REMARK 245                                    CHAMBER WITH CONTROLLED HUMIDITY.
REMARK 245   SAMPLE BUFFER                  : 10 MM TRIS, 1 MM MGCL2
REMARK 245   PH                             : 7.50
REMARK 245   SAMPLE DETAILS                 : E1B GENE-ATTENUATED ONCOLYTIC
REMARK 245  HUMAN ADENOVIRUS TYPE 5 WAS PROPAGATED IN HEK 293 CELLS,
REMARK 245  HARVESTED AND LIBERATED BY 3 CYCLES OF FREEZING-THAWING AND
REMARK 245  PURIFIED BY CSCL STEP GRADIENT ULTRA-CENTRIFUGATION. THE VIRION
REMARK 245  PARTICLES WERE THEN DIALYZED AND RESUSPENDED IN 10 MM TRIS (PH
REMARK 245  7.5), 1 MM MGCL2.
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245   DATE OF EXPERIMENT                : 01-MAY-09
REMARK 245   NUMBER OF MICROGRAPHS-IMAGES      : 1350
REMARK 245   TEMPERATURE (KELVIN)              : 90.00
REMARK 245   MICROSCOPE MODEL                  : FEI TITAN KRIOS
REMARK 245   DETECTOR TYPE                     : KODAK SO163 FILM
REMARK 245   MINIMUM DEFOCUS (NM)              : 1000.00
REMARK 245   MAXIMUM DEFOCUS (NM)              : 2500.00
REMARK 245   MINIMUM TILT ANGLE (DEGREES)      : 0.00
REMARK 245   MAXIMUM TILT ANGLE (DEGREES)      : 0.00
REMARK 245   NOMINAL CS                        : 2.70
REMARK 245   IMAGING MODE                      : BRIGHT FIELD
REMARK 245   ELECTRON DOSE (ELECTRONS NM**-2)  : 20.00
REMARK 245   ILLUMINATION MODE                 : FLOOD BEAM
REMARK 245   NOMINAL MAGNIFICATION             : 59000
REMARK 245   CALIBRATED MAGNIFICATION          : NULL
REMARK 245   SOURCE                            : FIELD EMISSION GUN
REMARK 245   ACCELERATION VOLTAGE (KV)         : 300
REMARK 245   IMAGING DETAILS                   : LOW-DOSE
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247  THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247  MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247  THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247  ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247  OF THE STRUCTURE FACTORS.
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 1
REMARK 290
REMARK 290      SYMOP   SYMMETRY
REMARK 290     NNNMMM   OPERATOR
REMARK 290       1555   X,Y,Z
REMARK 290
REMARK 290     WHERE NNN -> OPERATOR NUMBER
REMARK 290           MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 300 THE ASSEMBLY REPRESENTED IN THIS ENTRY HAS REGULAR
REMARK 300 ICOSAHEDRAL POINT SYMMETRY (SCHOENFLIES SYMBOL = I).
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I,
REMARK 350                    AND CHAINS: J, K, L, M, N, O, P, Q, R,
REMARK 350                    AND CHAINS: S, T
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT1   2  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT2   2  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT3   2  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT1   3 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT2   3  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT3   3  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT1   4 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT2   4 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT3   4  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT1   5  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT2   5 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT3   5  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT1   6 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2   6  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT3   6  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT1   7 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT2   7 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT3   7  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT1   8  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT2   8 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT3   8  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT1   9  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT2   9  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT3   9  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT1  10 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  10  0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  10  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT1  11  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2  11  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT3  11  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT1  12  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT2  12 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT3  12 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  13 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT2  13 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT3  13 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  14 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT2  14  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  14 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  15  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT2  15  0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  15 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  16 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2  16  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT3  16  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT1  17 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  17  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  17 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  18  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  18  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  18 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  19  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  19 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT3  19 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  20 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  20 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT3  20 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  21  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT2  21  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT3  21  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT1  22 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT2  22 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  22  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT1  23 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT2  23 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  23 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT1  24  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  24 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  24 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT1  25  0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  25 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  25  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT1  26  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT2  26  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT3  26 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT1  27  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  27 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  27 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  28  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  28 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  28  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  29 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT2  29 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT3  29  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  30 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT2  30 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  30 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  31  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT2  31  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT3  31  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT1  32  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  32  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT3  32  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT1  33  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  33  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT3  33 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT1  34 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT2  34  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT3  34 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT1  35 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT2  35  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT3  35  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT1  36  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT2  36  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT3  36 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT1  37 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT2  37  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT3  37 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  38 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT2  38  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT3  38  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  39  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT2  39  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT3  39  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT1  40  0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  40  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT3  40 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  41  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT2  41 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT3  41  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT1  42  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT2  42 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  42 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT1  43  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT2  43  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  43 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT1  44  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT2  44  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  44  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  45  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT2  45 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  45  0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  46  0.000000  0.000000  1.000000        0.00000
REMARK 350   BIOMT2  46  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT3  46  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT1  47  0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT2  47  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT3  47  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  48  0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT2  48 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT3  48  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  49  0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT2  49 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT3  49 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT1  50  0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT2  50  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT3  50 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT1  51  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT2  51 -1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT3  51  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT1  52 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  52 -0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  52  0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT1  53 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  53  0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  53  0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  54 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  54  0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT3  54 -0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT1  55 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  55 -0.500000 -0.809017 -0.309017        0.00000
REMARK 350   BIOMT3  55 -0.809017  0.309017  0.500000        0.00000
REMARK 350   BIOMT1  56  0.000000  0.000000 -1.000000        0.00000
REMARK 350   BIOMT2  56  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT3  56  0.000000 -1.000000  0.000000        0.00000
REMARK 350   BIOMT1  57 -0.309017 -0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  57  0.500000 -0.809017  0.309017        0.00000
REMARK 350   BIOMT3  57 -0.809017 -0.309017  0.500000        0.00000
REMARK 350   BIOMT1  58 -0.809017 -0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  58 -0.309017 -0.500000  0.809017        0.00000
REMARK 350   BIOMT3  58 -0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT1  59 -0.809017  0.309017 -0.500000        0.00000
REMARK 350   BIOMT2  59 -0.309017  0.500000  0.809017        0.00000
REMARK 350   BIOMT3  59  0.500000  0.809017 -0.309017        0.00000
REMARK 350   BIOMT1  60 -0.309017  0.500000 -0.809017        0.00000
REMARK 350   BIOMT2  60  0.500000  0.809017  0.309017        0.00000
REMARK 350   BIOMT3  60  0.809017 -0.309017 -0.500000        0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465   M RES C SSSEQI
REMARK 465     MET A     0
REMARK 465     ALA A     1
REMARK 465     THR A     2
REMARK 465     PRO A     3
REMARK 465     SER A     4
REMARK 465     MET A     5
REMARK 465     GLU A   136
REMARK 465     ALA A   137
REMARK 465     ALA A   138
REMARK 465     THR A   139
REMARK 465     ALA A   140
REMARK 465     LEU A   141
REMARK 465     GLU A   142
REMARK 465     ILE A   143
REMARK 465     ASN A   144
REMARK 465     LEU A   145
REMARK 465     GLU A   146
REMARK 465     GLU A   147
REMARK 465     GLU A   148
REMARK 465     ASP A   149
REMARK 465     ASP A   150
REMARK 465     ASP A   151
REMARK 465     ASN A   152
REMARK 465     GLU A   153
REMARK 465     ASP A   154
REMARK 465     GLU A   155
REMARK 465     VAL A   156
REMARK 465     ASP A   157
REMARK 465     GLU A   158
REMARK 465     GLN A   159
REMARK 465     ALA A   160
REMARK 465     GLU A   161
REMARK 465     GLN A   162
REMARK 465     GLN A   163
REMARK 465     LYS A   164
REMARK 465     THR A   950
REMARK 465     THR A   951
REMARK 465     MET B     0
REMARK 465     ALA B     1
REMARK 465     THR B     2
REMARK 465     PRO B     3
REMARK 465     SER B     4
REMARK 465     MET B     5
REMARK 465     GLU B   136
REMARK 465     ALA B   137
REMARK 465     ALA B   138
REMARK 465     THR B   139
REMARK 465     ALA B   140
REMARK 465     LEU B   141
REMARK 465     GLU B   142
REMARK 465     ILE B   143
REMARK 465     ASN B   144
REMARK 465     LEU B   145
REMARK 465     GLU B   146
REMARK 465     GLU B   147
REMARK 465     GLU B   148
REMARK 465     ASP B   149
REMARK 465     ASP B   150
REMARK 465     ASP B   151
REMARK 465     ASN B   152
REMARK 465     GLU B   153
REMARK 465     ASP B   154
REMARK 465     GLU B   155
REMARK 465     VAL B   156
REMARK 465     ASP B   157
REMARK 465     GLU B   158
REMARK 465     GLN B   159
REMARK 465     ALA B   160
REMARK 465     GLU B   161
REMARK 465     GLN B   162
REMARK 465     GLN B   163
REMARK 465     LYS B   164
REMARK 465     THR B   950
REMARK 465     THR B   951
REMARK 465     MET C     0
REMARK 465     ALA C     1
REMARK 465     GLU C   136
REMARK 465     ALA C   137
REMARK 465     ALA C   138
REMARK 465     THR C   139
REMARK 465     ALA C   140
REMARK 465     LEU C   141
REMARK 465     GLU C   142
REMARK 465     ILE C   143
REMARK 465     ASN C   144
REMARK 465     LEU C   145
REMARK 465     GLU C   146
REMARK 465     GLU C   147
REMARK 465     GLU C   148
REMARK 465     ASP C   149
REMARK 465     ASP C   150
REMARK 465     ASP C   151
REMARK 465     ASN C   152
REMARK 465     GLU C   153
REMARK 465     ASP C   154
REMARK 465     GLU C   155
REMARK 465     VAL C   156
REMARK 465     ASP C   157
REMARK 465     GLU C   158
REMARK 465     GLN C   159
REMARK 465     ALA C   160
REMARK 465     GLU C   161
REMARK 465     GLN C   162
REMARK 465     GLN C   163
REMARK 465     LYS C   164
REMARK 465     THR C   951
REMARK 465     MET D     0
REMARK 465     ALA D     1
REMARK 465     THR D     2
REMARK 465     PRO D     3
REMARK 465     SER D     4
REMARK 465     GLU D   136
REMARK 465     ALA D   137
REMARK 465     ALA D   138
REMARK 465     THR D   139
REMARK 465     ALA D   140
REMARK 465     LEU D   141
REMARK 465     GLU D   142
REMARK 465     ILE D   143
REMARK 465     ASN D   144
REMARK 465     LEU D   145
REMARK 465     GLU D   146
REMARK 465     GLU D   147
REMARK 465     GLU D   148
REMARK 465     ASP D   149
REMARK 465     ASP D   150
REMARK 465     ASP D   151
REMARK 465     ASN D   152
REMARK 465     GLU D   153
REMARK 465     ASP D   154
REMARK 465     GLU D   155
REMARK 465     VAL D   156
REMARK 465     ASP D   157
REMARK 465     GLU D   158
REMARK 465     GLN D   159
REMARK 465     ALA D   160
REMARK 465     GLU D   161
REMARK 465     GLN D   162
REMARK 465     GLN D   163
REMARK 465     LYS D   164
REMARK 465     THR D   950
REMARK 465     THR D   951
REMARK 465     MET E     0
REMARK 465     ALA E     1
REMARK 465     THR E     2
REMARK 465     PRO E     3
REMARK 465     SER E     4
REMARK 465     GLU E   136
REMARK 465     ALA E   137
REMARK 465     ALA E   138
REMARK 465     THR E   139
REMARK 465     ALA E   140
REMARK 465     LEU E   141
REMARK 465     GLU E   142
REMARK 465     ILE E   143
REMARK 465     ASN E   144
REMARK 465     LEU E   145
REMARK 465     GLU E   146
REMARK 465     GLU E   147
REMARK 465     GLU E   148
REMARK 465     ASP E   149
REMARK 465     ASP E   150
REMARK 465     ASP E   151
REMARK 465     ASN E   152
REMARK 465     GLU E   153
REMARK 465     ASP E   154
REMARK 465     GLU E   155
REMARK 465     VAL E   156
REMARK 465     ASP E   157
REMARK 465     GLU E   158
REMARK 465     GLN E   159
REMARK 465     ALA E   160
REMARK 465     GLU E   161
REMARK 465     GLN E   162
REMARK 465     GLN E   163
REMARK 465     LYS E   164
REMARK 465     THR E   951
REMARK 465     MET F     0
REMARK 465     ALA F     1
REMARK 465     THR F     2
REMARK 465     PRO F     3
REMARK 465     SER F     4
REMARK 465     GLU F   136
REMARK 465     ALA F   137
REMARK 465     ALA F   138
REMARK 465     THR F   139
REMARK 465     ALA F   140
REMARK 465     LEU F   141
REMARK 465     GLU F   142
REMARK 465     ILE F   143
REMARK 465     ASN F   144
REMARK 465     LEU F   145
REMARK 465     GLU F   146
REMARK 465     GLU F   147
REMARK 465     GLU F   148
REMARK 465     ASP F   149
REMARK 465     ASP F   150
REMARK 465     ASP F   151
REMARK 465     ASN F   152
REMARK 465     GLU F   153
REMARK 465     ASP F   154
REMARK 465     GLU F   155
REMARK 465     VAL F   156
REMARK 465     ASP F   157
REMARK 465     GLU F   158
REMARK 465     GLN F   159
REMARK 465     ALA F   160
REMARK 465     GLU F   161
REMARK 465     GLN F   162
REMARK 465     GLN F   163
REMARK 465     LYS F   164
REMARK 465     THR F   951
REMARK 465     MET G     0
REMARK 465     ALA G     1
REMARK 465     THR G     2
REMARK 465     PRO G     3
REMARK 465     SER G     4
REMARK 465     GLU G   136
REMARK 465     ALA G   137
REMARK 465     ALA G   138
REMARK 465     THR G   139
REMARK 465     ALA G   140
REMARK 465     LEU G   141
REMARK 465     GLU G   142
REMARK 465     ILE G   143
REMARK 465     ASN G   144
REMARK 465     LEU G   145
REMARK 465     GLU G   146
REMARK 465     GLU G   147
REMARK 465     GLU G   148
REMARK 465     ASP G   149
REMARK 465     ASP G   150
REMARK 465     ASP G   151
REMARK 465     ASN G   152
REMARK 465     GLU G   153
REMARK 465     ASP G   154
REMARK 465     GLU G   155
REMARK 465     VAL G   156
REMARK 465     ASP G   157
REMARK 465     GLU G   158
REMARK 465     GLN G   159
REMARK 465     ALA G   160
REMARK 465     GLU G   161
REMARK 465     GLN G   162
REMARK 465     GLN G   163
REMARK 465     LYS G   164
REMARK 465     THR G   951
REMARK 465     MET H     0
REMARK 465     ALA H     1
REMARK 465     GLU H   136
REMARK 465     ALA H   137
REMARK 465     ALA H   138
REMARK 465     THR H   139
REMARK 465     ALA H   140
REMARK 465     LEU H   141
REMARK 465     GLU H   142
REMARK 465     ILE H   143
REMARK 465     ASN H   144
REMARK 465     LEU H   145
REMARK 465     GLU H   146
REMARK 465     GLU H   147
REMARK 465     GLU H   148
REMARK 465     ASP H   149
REMARK 465     ASP H   150
REMARK 465     ASP H   151
REMARK 465     ASN H   152
REMARK 465     GLU H   153
REMARK 465     ASP H   154
REMARK 465     GLU H   155
REMARK 465     VAL H   156
REMARK 465     ASP H   157
REMARK 465     GLU H   158
REMARK 465     GLN H   159
REMARK 465     ALA H   160
REMARK 465     GLU H   161
REMARK 465     GLN H   162
REMARK 465     GLN H   163
REMARK 465     LYS H   164
REMARK 465     THR H   950
REMARK 465     THR H   951
REMARK 465     MET I     0
REMARK 465     ALA I     1
REMARK 465     THR I     2
REMARK 465     PRO I     3
REMARK 465     SER I     4
REMARK 465     GLU I   136
REMARK 465     ALA I   137
REMARK 465     ALA I   138
REMARK 465     THR I   139
REMARK 465     ALA I   140
REMARK 465     LEU I   141
REMARK 465     GLU I   142
REMARK 465     ILE I   143
REMARK 465     ASN I   144
REMARK 465     LEU I   145
REMARK 465     GLU I   146
REMARK 465     GLU I   147
REMARK 465     GLU I   148
REMARK 465     ASP I   149
REMARK 465     ASP I   150
REMARK 465     ASP I   151
REMARK 465     ASN I   152
REMARK 465     GLU I   153
REMARK 465     ASP I   154
REMARK 465     GLU I   155
REMARK 465     VAL I   156
REMARK 465     ASP I   157
REMARK 465     GLU I   158
REMARK 465     GLN I   159
REMARK 465     ALA I   160
REMARK 465     GLU I   161
REMARK 465     GLN I   162
REMARK 465     GLN I   163
REMARK 465     LYS I   164
REMARK 465     THR I   951
REMARK 465     MET J     0
REMARK 465     ALA J     1
REMARK 465     THR J     2
REMARK 465     PRO J     3
REMARK 465     SER J     4
REMARK 465     GLU J   136
REMARK 465     ALA J   137
REMARK 465     ALA J   138
REMARK 465     THR J   139
REMARK 465     ALA J   140
REMARK 465     LEU J   141
REMARK 465     GLU J   142
REMARK 465     ILE J   143
REMARK 465     ASN J   144
REMARK 465     LEU J   145
REMARK 465     GLU J   146
REMARK 465     GLU J   147
REMARK 465     GLU J   148
REMARK 465     ASP J   149
REMARK 465     ASP J   150
REMARK 465     ASP J   151
REMARK 465     ASN J   152
REMARK 465     GLU J   153
REMARK 465     ASP J   154
REMARK 465     GLU J   155
REMARK 465     VAL J   156
REMARK 465     ASP J   157
REMARK 465     GLU J   158
REMARK 465     GLN J   159
REMARK 465     ALA J   160
REMARK 465     GLU J   161
REMARK 465     GLN J   162
REMARK 465     GLN J   163
REMARK 465     LYS J   164
REMARK 465     MET K     0
REMARK 465     ALA K     1
REMARK 465     THR K     2
REMARK 465     GLU K   136
REMARK 465     ALA K   137
REMARK 465     ALA K   138
REMARK 465     THR K   139
REMARK 465     ALA K   140
REMARK 465     LEU K   141
REMARK 465     GLU K   142
REMARK 465     ILE K   143
REMARK 465     ASN K   144
REMARK 465     LEU K   145
REMARK 465     GLU K   146
REMARK 465     GLU K   147
REMARK 465     GLU K   148
REMARK 465     ASP K   149
REMARK 465     ASP K   150
REMARK 465     ASP K   151
REMARK 465     ASN K   152
REMARK 465     GLU K   153
REMARK 465     ASP K   154
REMARK 465     GLU K   155
REMARK 465     VAL K   156
REMARK 465     ASP K   157
REMARK 465     GLU K   158
REMARK 465     GLN K   159
REMARK 465     ALA K   160
REMARK 465     GLU K   161
REMARK 465     GLN K   162
REMARK 465     GLN K   163
REMARK 465     LYS K   164
REMARK 465     THR K   951
REMARK 465     MET L     0
REMARK 465     ALA L     1
REMARK 465     GLU L   136
REMARK 465     ALA L   137
REMARK 465     ALA L   138
REMARK 465     THR L   139
REMARK 465     ALA L   140
REMARK 465     LEU L   141
REMARK 465     GLU L   142
REMARK 465     ILE L   143
REMARK 465     ASN L   144
REMARK 465     LEU L   145
REMARK 465     GLU L   146
REMARK 465     GLU L   147
REMARK 465     GLU L   148
REMARK 465     ASP L   149
REMARK 465     ASP L   150
REMARK 465     ASP L   151
REMARK 465     ASN L   152
REMARK 465     GLU L   153
REMARK 465     ASP L   154
REMARK 465     GLU L   155
REMARK 465     VAL L   156
REMARK 465     ASP L   157
REMARK 465     GLU L   158
REMARK 465     GLN L   159
REMARK 465     ALA L   160
REMARK 465     GLU L   161
REMARK 465     GLN L   162
REMARK 465     GLN L   163
REMARK 465     LYS L   164
REMARK 465     THR L   950
REMARK 465     THR L   951
REMARK 465     MET M     1
REMARK 465     ARG M     2
REMARK 465     ARG M     3
REMARK 465     ALA M     4
REMARK 465     ALA M     5
REMARK 465     MET M     6
REMARK 465     TYR M     7
REMARK 465     GLU M     8
REMARK 465     GLU M     9
REMARK 465     GLY M    10
REMARK 465     PRO M    11
REMARK 465     PRO M    12
REMARK 465     PRO M    13
REMARK 465     SER M    14
REMARK 465     TYR M    15
REMARK 465     GLU M    16
REMARK 465     SER M    17
REMARK 465     VAL M    18
REMARK 465     VAL M    19
REMARK 465     SER M    20
REMARK 465     ALA M    21
REMARK 465     ALA M    22
REMARK 465     PRO M    23
REMARK 465     VAL M    24
REMARK 465     ALA M    25
REMARK 465     ALA M    26
REMARK 465     ALA M    27
REMARK 465     LEU M    28
REMARK 465     GLY M    29
REMARK 465     SER M    30
REMARK 465     PRO M    31
REMARK 465     PHE M    32
REMARK 465     ASP M    33
REMARK 465     ALA M    34
REMARK 465     PRO M    35
REMARK 465     LEU M    36
REMARK 465     LYS M   297
REMARK 465     ASP M   298
REMARK 465     ASP M   299
REMARK 465     THR M   300
REMARK 465     GLU M   301
REMARK 465     GLN M   302
REMARK 465     GLY M   303
REMARK 465     GLY M   304
REMARK 465     GLY M   305
REMARK 465     GLY M   306
REMARK 465     ALA M   307
REMARK 465     GLY M   308
REMARK 465     GLY M   309
REMARK 465     SER M   310
REMARK 465     ASN M   311
REMARK 465     SER M   312
REMARK 465     SER M   313
REMARK 465     GLY M   314
REMARK 465     SER M   315
REMARK 465     GLY M   316
REMARK 465     ALA M   317
REMARK 465     GLU M   318
REMARK 465     GLU M   319
REMARK 465     ASN M   320
REMARK 465     SER M   321
REMARK 465     ASN M   322
REMARK 465     ALA M   323
REMARK 465     ALA M   324
REMARK 465     ALA M   325
REMARK 465     ALA M   326
REMARK 465     ALA M   327
REMARK 465     MET M   328
REMARK 465     GLN M   329
REMARK 465     PRO M   330
REMARK 465     VAL M   331
REMARK 465     GLU M   332
REMARK 465     ASP M   333
REMARK 465     MET M   334
REMARK 465     ASN M   335
REMARK 465     ASP M   336
REMARK 465     HIS M   337
REMARK 465     ALA M   338
REMARK 465     ILE M   339
REMARK 465     ARG M   340
REMARK 465     GLY M   341
REMARK 465     ASP M   342
REMARK 465     THR M   343
REMARK 465     PHE M   344
REMARK 465     ALA M   345
REMARK 465     THR M   346
REMARK 465     ARG M   347
REMARK 465     ALA M   348
REMARK 465     GLU M   349
REMARK 465     GLU M   350
REMARK 465     LYS M   351
REMARK 465     ARG M   352
REMARK 465     ALA M   353
REMARK 465     GLU M   354
REMARK 465     ALA M   355
REMARK 465     GLU M   356
REMARK 465     ALA M   357
REMARK 465     ALA M   358
REMARK 465     ALA M   359
REMARK 465     GLU M   360
REMARK 465     ALA M   361
REMARK 465     ALA M   362
REMARK 465     ALA M   363
REMARK 465     PRO M   364
REMARK 465     ALA M   365
REMARK 465     ALA M   366
REMARK 465     GLN M   367
REMARK 465     PRO M   368
REMARK 465     GLU M   369
REMARK 465     VAL M   370
REMARK 465     GLU M   371
REMARK 465     LYS M   372
REMARK 465     PRO M   373
REMARK 465     GLN M   374
REMARK 465     THR M   570
REMARK 465     PHE M   571
REMARK 465     MET N     1
REMARK 465     MET N     2
REMARK 465     GLN N     3
REMARK 465     ASP N     4
REMARK 465     ALA N     5
REMARK 465     THR N     6
REMARK 465     ALA N   216
REMARK 465     PRO N   217
REMARK 465     THR N   218
REMARK 465     GLY N   219
REMARK 465     ASP N   220
REMARK 465     ARG N   221
REMARK 465     ALA N   222
REMARK 465     THR N   223
REMARK 465     VAL N   224
REMARK 465     SER N   225
REMARK 465     LEU N   301
REMARK 465     THR N   302
REMARK 465     ASN N   303
REMARK 465     ARG N   304
REMARK 465     ARG N   305
REMARK 465     GLN N   306
REMARK 465     LYS N   307
REMARK 465     ILE N   308
REMARK 465     PRO N   309
REMARK 465     SER N   310
REMARK 465     LEU N   311
REMARK 465     HIS N   312
REMARK 465     SER N   313
REMARK 465     LEU N   314
REMARK 465     ASN N   315
REMARK 465     SER N   316
REMARK 465     GLU N   317
REMARK 465     GLU N   318
REMARK 465     GLU N   319
REMARK 465     ARG N   320
REMARK 465     ILE N   321
REMARK 465     LEU N   322
REMARK 465     ARG N   323
REMARK 465     TYR N   324
REMARK 465     VAL N   325
REMARK 465     GLN N   326
REMARK 465     GLN N   327
REMARK 465     SER N   328
REMARK 465     VAL N   329
REMARK 465     SER N   330
REMARK 465     LEU N   331
REMARK 465     ASN N   332
REMARK 465     LEU N   333
REMARK 465     MET N   334
REMARK 465     ARG N   335
REMARK 465     ASP N   336
REMARK 465     GLY N   337
REMARK 465     VAL N   338
REMARK 465     THR N   339
REMARK 465     PRO N   340
REMARK 465     SER N   341
REMARK 465     VAL N   342
REMARK 465     ALA N   343
REMARK 465     LEU N   344
REMARK 465     ASP N   345
REMARK 465     MET N   346
REMARK 465     THR N   347
REMARK 465     ALA N   348
REMARK 465     ARG N   349
REMARK 465     ASN N   350
REMARK 465     MET N   351
REMARK 465     GLU N   352
REMARK 465     PRO N   353
REMARK 465     GLY N   354
REMARK 465     MET N   355
REMARK 465     TYR N   356
REMARK 465     ALA N   357
REMARK 465     SER N   358
REMARK 465     ASN N   359
REMARK 465     ARG N   360
REMARK 465     PRO N   361
REMARK 465     PHE N   362
REMARK 465     ILE N   363
REMARK 465     ASN N   364
REMARK 465     ARG N   365
REMARK 465     LEU N   366
REMARK 465     MET N   367
REMARK 465     ASP N   368
REMARK 465     TYR N   369
REMARK 465     LEU N   370
REMARK 465     HIS N   371
REMARK 465     ARG N   372
REMARK 465     ALA N   373
REMARK 465     ALA N   374
REMARK 465     ALA N   375
REMARK 465     VAL N   376
REMARK 465     ASN N   377
REMARK 465     PRO N   378
REMARK 465     GLU N   379
REMARK 465     TYR N   380
REMARK 465     PHE N   381
REMARK 465     THR N   382
REMARK 465     ASN N   383
REMARK 465     ALA N   384
REMARK 465     ILE N   385
REMARK 465     LEU N   386
REMARK 465     ASN N   387
REMARK 465     PRO N   388
REMARK 465     HIS N   389
REMARK 465     TRP N   390
REMARK 465     LEU N   391
REMARK 465     PRO N   392
REMARK 465     PRO N   393
REMARK 465     PRO N   394
REMARK 465     GLY N   395
REMARK 465     PHE N   396
REMARK 465     TYR N   397
REMARK 465     THR N   398
REMARK 465     GLY N   399
REMARK 465     GLY N   400
REMARK 465     PHE N   401
REMARK 465     GLU N   402
REMARK 465     VAL N   403
REMARK 465     PRO N   404
REMARK 465     GLU N   405
REMARK 465     GLY N   406
REMARK 465     ASN N   407
REMARK 465     ASP N   408
REMARK 465     GLY N   409
REMARK 465     PHE N   410
REMARK 465     LEU N   411
REMARK 465     TRP N   412
REMARK 465     ASP N   413
REMARK 465     ASP N   414
REMARK 465     ILE N   415
REMARK 465     ASP N   416
REMARK 465     ASP N   417
REMARK 465     SER N   418
REMARK 465     VAL N   419
REMARK 465     PHE N   420
REMARK 465     SER N   421
REMARK 465     PRO N   422
REMARK 465     GLN N   423
REMARK 465     PRO N   424
REMARK 465     GLN N   425
REMARK 465     THR N   426
REMARK 465     LEU N   427
REMARK 465     LEU N   428
REMARK 465     GLU N   429
REMARK 465     LEU N   430
REMARK 465     GLN N   431
REMARK 465     GLN N   432
REMARK 465     ARG N   433
REMARK 465     GLU N   434
REMARK 465     GLN N   435
REMARK 465     ALA N   436
REMARK 465     GLU N   437
REMARK 465     ALA N   438
REMARK 465     ALA N   439
REMARK 465     LEU N   440
REMARK 465     ARG N   441
REMARK 465     LYS N   442
REMARK 465     GLU N   443
REMARK 465     SER N   444
REMARK 465     PHE N   445
REMARK 465     ARG N   446
REMARK 465     ARG N   447
REMARK 465     PRO N   448
REMARK 465     SER N   449
REMARK 465     SER N   450
REMARK 465     LEU N   451
REMARK 465     SER N   452
REMARK 465     ASP N   453
REMARK 465     LEU N   454
REMARK 465     GLY N   455
REMARK 465     ALA N   456
REMARK 465     ALA N   457
REMARK 465     ALA N   458
REMARK 465     PRO N   459
REMARK 465     ARG N   460
REMARK 465     SER N   461
REMARK 465     ASP N   462
REMARK 465     ALA N   463
REMARK 465     SER N   464
REMARK 465     SER N   465
REMARK 465     PRO N   466
REMARK 465     PHE N   467
REMARK 465     PRO N   468
REMARK 465     SER N   469
REMARK 465     LEU N   470
REMARK 465     ILE N   471
REMARK 465     GLY N   472
REMARK 465     SER N   473
REMARK 465     LEU N   474
REMARK 465     THR N   475
REMARK 465     SER N   476
REMARK 465     THR N   477
REMARK 465     ARG N   478
REMARK 465     THR N   479
REMARK 465     THR N   480
REMARK 465     ARG N   481
REMARK 465     PRO N   482
REMARK 465     ARG N   483
REMARK 465     LEU N   484
REMARK 465     LEU N   485
REMARK 465     GLY N   486
REMARK 465     GLU N   487
REMARK 465     GLU N   488
REMARK 465     GLU N   489
REMARK 465     TYR N   490
REMARK 465     LEU N   491
REMARK 465     ASN N   492
REMARK 465     ASN N   493
REMARK 465     SER N   494
REMARK 465     LEU N   495
REMARK 465     LEU N   496
REMARK 465     GLN N   497
REMARK 465     PRO N   498
REMARK 465     GLN N   499
REMARK 465     ARG N   500
REMARK 465     GLU N   501
REMARK 465     LYS N   502
REMARK 465     ASN N   503
REMARK 465     LEU N   504
REMARK 465     PRO N   505
REMARK 465     PRO N   506
REMARK 465     ALA N   507
REMARK 465     PHE N   508
REMARK 465     PRO N   509
REMARK 465     ASN N   510
REMARK 465     ASN N   511
REMARK 465     GLY N   512
REMARK 465     ILE N   513
REMARK 465     GLU N   514
REMARK 465     SER N   515
REMARK 465     LEU N   516
REMARK 465     VAL N   517
REMARK 465     ASP N   518
REMARK 465     LYS N   519
REMARK 465     MET N   520
REMARK 465     SER N   521
REMARK 465     ARG N   522
REMARK 465     TRP N   523
REMARK 465     LYS N   524
REMARK 465     THR N   525
REMARK 465     TYR N   526
REMARK 465     ALA N   527
REMARK 465     GLN N   528
REMARK 465     GLU N   529
REMARK 465     HIS N   530
REMARK 465     ARG N   531
REMARK 465     ASP N   532
REMARK 465     VAL N   533
REMARK 465     PRO N   534
REMARK 465     GLY N   535
REMARK 465     PRO N   536
REMARK 465     ARG N   537
REMARK 465     PRO N   538
REMARK 465     PRO N   539
REMARK 465     THR N   540
REMARK 465     ARG N   541
REMARK 465     ARG N   542
REMARK 465     GLN N   543
REMARK 465     ARG N   544
REMARK 465     HIS N   545
REMARK 465     ASP N   546
REMARK 465     ARG N   547
REMARK 465     GLN N   548
REMARK 465     ARG N   549
REMARK 465     GLY N   550
REMARK 465     LEU N   551
REMARK 465     VAL N   552
REMARK 465     TRP N   553
REMARK 465     GLU N   554
REMARK 465     ASP N   555
REMARK 465     ASP N   556
REMARK 465     ASP N   557
REMARK 465     SER N   558
REMARK 465     ALA N   559
REMARK 465     ASP N   560
REMARK 465     ASP N   561
REMARK 465     SER N   562
REMARK 465     SER N   563
REMARK 465     VAL N   564
REMARK 465     LEU N   565
REMARK 465     ASP N   566
REMARK 465     LEU N   567
REMARK 465     GLY N   568
REMARK 465     GLY N   569
REMARK 465     SER N   570
REMARK 465     GLY N   571
REMARK 465     ASN N   572
REMARK 465     PRO N   573
REMARK 465     PHE N   574
REMARK 465     ALA N   575
REMARK 465     HIS N   576
REMARK 465     LEU N   577
REMARK 465     ARG N   578
REMARK 465     PRO N   579
REMARK 465     ARG N   580
REMARK 465     LEU N   581
REMARK 465     GLY N   582
REMARK 465     ARG N   583
REMARK 465     MET N   584
REMARK 465     PHE N   585
REMARK 465     MET O     1
REMARK 465     SER O     2
REMARK 465     GLY O   111
REMARK 465     PHE O   112
REMARK 465     ARG O   113
REMARK 465     HIS O   114
REMARK 465     ARG O   115
REMARK 465     VAL O   116
REMARK 465     ARG O   117
REMARK 465     SER O   118
REMARK 465     PRO O   119
REMARK 465     GLY O   120
REMARK 465     GLN O   121
REMARK 465     GLY O   122
REMARK 465     ILE O   123
REMARK 465     THR O   124
REMARK 465     HIS O   125
REMARK 465     LEU O   126
REMARK 465     THR O   127
REMARK 465     ILE O   128
REMARK 465     ARG O   129
REMARK 465     GLY O   130
REMARK 465     ARG O   131
REMARK 465     GLY O   132
REMARK 465     ILE O   133
REMARK 465     GLN O   134
REMARK 465     LEU O   135
REMARK 465     ASN O   136
REMARK 465     ASP O   137
REMARK 465     GLU O   138
REMARK 465     SER O   139
REMARK 465     VAL O   140
REMARK 465     SER O   141
REMARK 465     SER O   142
REMARK 465     SER O   143
REMARK 465     LEU O   144
REMARK 465     GLY O   145
REMARK 465     LEU O   146
REMARK 465     ARG O   147
REMARK 465     PRO O   148
REMARK 465     ASP O   149
REMARK 465     GLY O   150
REMARK 465     THR O   151
REMARK 465     PHE O   152
REMARK 465     GLN O   153
REMARK 465     ILE O   154
REMARK 465     GLY O   155
REMARK 465     GLY O   156
REMARK 465     ALA O   157
REMARK 465     GLY O   158
REMARK 465     ASP O   227
REMARK 465     MET P     1
REMARK 465     SER P     2
REMARK 465     GLY P   111
REMARK 465     PHE P   112
REMARK 465     ARG P   113
REMARK 465     HIS P   114
REMARK 465     ARG P   115
REMARK 465     VAL P   116
REMARK 465     ARG P   117
REMARK 465     SER P   118
REMARK 465     PRO P   119
REMARK 465     GLY P   120
REMARK 465     GLN P   121
REMARK 465     GLY P   122
REMARK 465     ILE P   123
REMARK 465     THR P   124
REMARK 465     HIS P   125
REMARK 465     LEU P   126
REMARK 465     THR P   127
REMARK 465     ILE P   128
REMARK 465     ARG P   129
REMARK 465     GLY P   130
REMARK 465     ARG P   131
REMARK 465     GLY P   132
REMARK 465     ILE P   133
REMARK 465     GLN P   134
REMARK 465     LEU P   135
REMARK 465     ASN P   136
REMARK 465     ASP P   137
REMARK 465     GLU P   138
REMARK 465     SER P   139
REMARK 465     VAL P   140
REMARK 465     SER P   141
REMARK 465     SER P   142
REMARK 465     SER P   143
REMARK 465     LEU P   144
REMARK 465     GLY P   145
REMARK 465     LEU P   146
REMARK 465     ARG P   147
REMARK 465     PRO P   148
REMARK 465     ASP P   149
REMARK 465     GLY P   150
REMARK 465     THR P   151
REMARK 465     PHE P   152
REMARK 465     GLN P   153
REMARK 465     ILE P   154
REMARK 465     GLY P   155
REMARK 465     GLY P   156
REMARK 465     ALA P   157
REMARK 465     GLY P   158
REMARK 465     ASP P   227
REMARK 465     MET Q     1
REMARK 465     SER Q     2
REMARK 465     THR Q     3
REMARK 465     ASN Q     4
REMARK 465     SER Q     5
REMARK 465     PHE Q     6
REMARK 465     SER Q   135
REMARK 465     PRO Q   136
REMARK 465     PRO Q   137
REMARK 465     ASN Q   138
REMARK 465     ALA Q   139
REMARK 465     VAL Q   140
REMARK 465     MET R     1
REMARK 465     SER R     2
REMARK 465     THR R     3
REMARK 465     ASN R     4
REMARK 465     SER R     5
REMARK 465     PHE R     6
REMARK 465     THR R    55
REMARK 465     PRO R    56
REMARK 465     LEU R    57
REMARK 465     GLU R    58
REMARK 465     THR R    59
REMARK 465     ALA R    60
REMARK 465     ALA R    61
REMARK 465     SER R    62
REMARK 465     ALA R    63
REMARK 465     ALA R    64
REMARK 465     ALA R    65
REMARK 465     SER R    66
REMARK 465     ALA R    67
REMARK 465     ALA R    68
REMARK 465     ALA R    69
REMARK 465     ALA R    70
REMARK 465     THR R    71
REMARK 465     ALA R    72
REMARK 465     ARG R    73
REMARK 465     GLY R    74
REMARK 465     ILE R    75
REMARK 465     VAL R    76
REMARK 465     THR R    77
REMARK 465     ASP R    78
REMARK 465     PHE R    79
REMARK 465     ALA R    80
REMARK 465     PHE R    81
REMARK 465     LEU R    82
REMARK 465     SER R    83
REMARK 465     PRO R    84
REMARK 465     LEU R    85
REMARK 465     ALA R    86
REMARK 465     SER R    87
REMARK 465     SER R    88
REMARK 465     ALA R    89
REMARK 465     ALA R    90
REMARK 465     SER R    91
REMARK 465     ARG R    92
REMARK 465     SER R    93
REMARK 465     SER R    94
REMARK 465     ASN R   138
REMARK 465     ALA R   139
REMARK 465     VAL R   140
REMARK 465     MET S     1
REMARK 465     SER S     2
REMARK 465     THR S     3
REMARK 465     ASN S     4
REMARK 465     SER S     5
REMARK 465     PHE S     6
REMARK 465     THR S    55
REMARK 465     PRO S    56
REMARK 465     LEU S    57
REMARK 465     GLU S    58
REMARK 465     THR S    59
REMARK 465     ALA S    60
REMARK 465     ALA S    61
REMARK 465     SER S    62
REMARK 465     ALA S    63
REMARK 465     ALA S    64
REMARK 465     ALA S    65
REMARK 465     SER S    66
REMARK 465     ALA S    67
REMARK 465     ALA S    68
REMARK 465     ALA S    69
REMARK 465     ALA S    70
REMARK 465     THR S    71
REMARK 465     ALA S    72
REMARK 465     ARG S    73
REMARK 465     GLY S    74
REMARK 465     ILE S    75
REMARK 465     VAL S    76
REMARK 465     THR S    77
REMARK 465     ASP S    78
REMARK 465     PHE S    79
REMARK 465     ALA S    80
REMARK 465     PHE S    81
REMARK 465     LEU S    82
REMARK 465     SER S    83
REMARK 465     PRO S    84
REMARK 465     LEU S    85
REMARK 465     ALA S    86
REMARK 465     SER S    87
REMARK 465     SER S    88
REMARK 465     ALA S    89
REMARK 465     ALA S    90
REMARK 465     SER S    91
REMARK 465     ARG S    92
REMARK 465     LEU S   131
REMARK 465     LYS S   132
REMARK 465     ALA S   133
REMARK 465     SER S   134
REMARK 465     SER S   135
REMARK 465     PRO S   136
REMARK 465     PRO S   137
REMARK 465     ASN S   138
REMARK 465     ALA S   139
REMARK 465     VAL S   140
REMARK 465     MET T     1
REMARK 465     SER T     2
REMARK 465     THR T     3
REMARK 465     ASN T     4
REMARK 465     SER T     5
REMARK 465     PHE T     6
REMARK 465     THR T    55
REMARK 465     PRO T    56
REMARK 465     LEU T    57
REMARK 465     GLU T    58
REMARK 465     THR T    59
REMARK 465     ALA T    60
REMARK 465     ALA T    61
REMARK 465     SER T    62
REMARK 465     ALA T    63
REMARK 465     ALA T    64
REMARK 465     ALA T    65
REMARK 465     SER T    66
REMARK 465     ALA T    67
REMARK 465     ALA T    68
REMARK 465     ALA T    69
REMARK 465     ALA T    70
REMARK 465     THR T    71
REMARK 465     ALA T    72
REMARK 465     ARG T    73
REMARK 465     GLY T    74
REMARK 465     ILE T    75
REMARK 465     VAL T    76
REMARK 465     THR T    77
REMARK 465     ASP T    78
REMARK 465     PHE T    79
REMARK 465     ALA T    80
REMARK 465     PHE T    81
REMARK 465     LEU T    82
REMARK 465     SER T    83
REMARK 465     PRO T    84
REMARK 465     LEU T    85
REMARK 465     ALA T    86
REMARK 465     SER T    87
REMARK 465     SER T    88
REMARK 465     ALA T    89
REMARK 465     ALA T    90
REMARK 465     SER T    91
REMARK 465     ARG T    92
REMARK 465     SER T    93
REMARK 465     SER T    94
REMARK 465     ALA T    95
REMARK 465     ARG T    96
REMARK 465     ASP T    97
REMARK 465     SER T   134
REMARK 465     SER T   135
REMARK 465     PRO T   136
REMARK 465     PRO T   137
REMARK 465     ASN T   138
REMARK 465     ALA T   139
REMARK 465     VAL T   140
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470   M RES CSSEQI  ATOMS
REMARK 470     THR A 272    OG1  CG2
REMARK 470     THR B 272    OG1  CG2
REMARK 470     THR C 272    OG1  CG2
REMARK 470     THR D 272    OG1  CG2
REMARK 470     THR E 272    OG1  CG2
REMARK 470     THR F 272    OG1  CG2
REMARK 470     THR G 272    OG1  CG2
REMARK 470     THR H 272    OG1  CG2
REMARK 470     THR I 272    OG1  CG2
REMARK 470     THR J 272    OG1  CG2
REMARK 470     THR K 272    OG1  CG2
REMARK 470     THR L 272    OG1  CG2
REMARK 470     SER O 104    OG
REMARK 470     SER P 104    OG
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3
REMARK 500    PRO A 192   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO A 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO B 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO B 739   C   -  N   -  CA  ANGL. DEV. =   9.9 DEGREES
REMARK 500    PRO C 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO D 192   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO D 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO E 192   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO E 739   C   -  N   -  CA  ANGL. DEV. =  10.0 DEGREES
REMARK 500    PRO F 192   C   -  N   -  CD  ANGL. DEV. = -18.0 DEGREES
REMARK 500    PRO F 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO G 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO G 667   C   -  N   -  CD  ANGL. DEV. = -15.5 DEGREES
REMARK 500    PRO G 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO H 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO H 739   C   -  N   -  CA  ANGL. DEV. =   9.9 DEGREES
REMARK 500    PRO I 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO I 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO J 192   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO J 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO K   7   C   -  N   -  CD  ANGL. DEV. = -12.6 DEGREES
REMARK 500    PRO K 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO K 667   C   -  N   -  CD  ANGL. DEV. = -14.4 DEGREES
REMARK 500    PRO K 739   C   -  N   -  CA  ANGL. DEV. =   9.9 DEGREES
REMARK 500    PRO L   3   C   -  N   -  CD  ANGL. DEV. = -13.1 DEGREES
REMARK 500    PRO L 192   C   -  N   -  CD  ANGL. DEV. = -18.1 DEGREES
REMARK 500    PRO L 739   C   -  N   -  CA  ANGL. DEV. =   9.8 DEGREES
REMARK 500    PRO M 153   C   -  N   -  CD  ANGL. DEV. = -18.0 DEGREES
REMARK 500    PRO O 209   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO P 209   C   -  N   -  CD  ANGL. DEV. = -18.2 DEGREES
REMARK 500    PRO Q  56   C   -  N   -  CD  ANGL. DEV. = -13.9 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500  M RES CSSEQI        PSI       PHI
REMARK 500    PRO A   7      -22.88    -34.82
REMARK 500    SER A  24      131.71    -32.10
REMARK 500    GLU A  35       24.34    -58.03
REMARK 500    THR A  36      -66.71   -124.37
REMARK 500    HIS A  53      144.81   -179.62
REMARK 500    VAL A  55      -64.80   -144.63
REMARK 500    ASN A  90       28.92     44.26
REMARK 500    PRO A 114       39.40    -73.11
REMARK 500    LYS A 126       -4.75    -57.81
REMARK 500    VAL A 187      112.41   -167.40
REMARK 500    GLU A 188       88.56    -66.54
REMARK 500    PHE A 199       -2.21   -147.68
REMARK 500    GLU A 214       92.88     68.30
REMARK 500    ILE A 248      -97.50    157.05
REMARK 500    LEU A 249       35.94    115.04
REMARK 500    LYS A 251     -168.52     88.57
REMARK 500    ASN A 254     -109.20     39.74
REMARK 500    LEU A 257     -150.98    -59.33
REMARK 500    GLU A 258     -174.21    -59.30
REMARK 500    SER A 259      -97.99   -104.26
REMARK 500    GLN A 260     -140.98   -170.16
REMARK 500    VAL A 261      159.78    123.26
REMARK 500    THR A 269       36.25     73.67
REMARK 500    ALA A 271      132.69     68.99
REMARK 500    ASN A 275      -82.56   -104.86
REMARK 500    LEU A 279       10.26    -56.50
REMARK 500    THR A 280      125.68    -27.91
REMARK 500    GLN A 353      -14.16     62.56
REMARK 500    VAL A 419      155.22    176.99
REMARK 500    ASN A 421       56.81    -92.22
REMARK 500    LYS A 431      120.08     64.33
REMARK 500    THR A 432      -41.96    121.64
REMARK 500    THR A 443       39.72    -81.05
REMARK 500    PHE A 445       62.82     71.16
REMARK 500    CYS A 515       -5.79    -57.33
REMARK 500    ASN A 518       51.00     38.39
REMARK 500    ASP A 603       31.41    -86.24
REMARK 500    ASN A 658       -4.27     69.58
REMARK 500    SER A 668      123.10    -34.83
REMARK 500    THR A 699       54.15   -116.57
REMARK 500    TYR A 712       14.95   -154.30
REMARK 500    SER A 727      -34.25   -176.12
REMARK 500    VAL A 748      -55.23     39.29
REMARK 500    ALA A 756       18.96     51.73
REMARK 500    ASP A 788       71.77   -101.88
REMARK 500    ARG A 789     -174.06    -69.95
REMARK 500    PRO A 833       39.70    -82.16
REMARK 500    TYR A 841      147.40    176.86
REMARK 500    CYS A 865       71.76   -160.34
REMARK 500    PHE A 878       -2.96     67.40
REMARK 500
REMARK 500 THIS ENTRY HAS     891 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-5172   RELATED DB: EMDB
DBREF  3IYN A    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN B    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN C    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN D    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN E    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN F    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN G    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN H    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN I    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN J    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN K    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN L    0   951  UNP    P04133   HEX_ADE05        1    952
DBREF  3IYN M    1   571  UNP    P12538   PEN3_ADE05       1    571
DBREF  3IYN N    1   585  UNP    P12537   HEX3_ADE05       1    585
DBREF  3IYN O    1   227  UNP    P24936   HEX8_ADE05       1    227
DBREF  3IYN P    1   227  UNP    P24936   HEX8_ADE05       1    227
DBREF  3IYN Q    1   140  UNP    P03281   HEX9_ADE05       1    140
DBREF  3IYN R    1   140  UNP    P03281   HEX9_ADE05       1    140
DBREF  3IYN S    1   140  UNP    P03281   HEX9_ADE05       1    140
DBREF  3IYN T    1   140  UNP    P03281   HEX9_ADE05       1    140
SEQRES   1 A  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 A  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 A  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 A  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 A  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 A  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 A  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 A  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 A  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 A  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 A  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 A  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 A  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 A  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 A  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 A  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 A  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 A  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 A  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 A  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 A  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 A  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 A  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 A  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 A  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 A  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 A  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 A  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 A  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 A  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 A  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 A  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 A  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 A  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 A  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 A  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 A  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 A  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 A  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 A  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 A  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 A  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 A  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 A  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 A  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 A  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 A  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 A  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 A  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 A  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 A  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 A  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 A  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 A  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 A  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 A  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 A  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 A  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 A  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 A  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 A  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 A  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 A  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 A  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 A  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 A  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 A  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 A  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 A  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 A  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 A  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 A  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 A  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 A  952  ALA THR THR
SEQRES   1 B  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 B  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 B  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 B  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 B  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 B  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 B  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 B  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 B  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 B  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 B  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 B  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 B  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 B  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 B  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 B  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 B  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 B  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 B  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 B  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 B  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 B  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 B  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 B  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 B  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 B  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 B  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 B  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 B  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 B  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 B  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 B  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 B  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 B  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 B  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 B  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 B  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 B  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 B  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 B  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 B  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 B  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 B  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 B  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 B  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 B  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 B  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 B  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 B  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 B  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 B  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 B  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 B  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 B  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 B  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 B  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 B  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 B  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 B  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 B  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 B  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 B  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 B  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 B  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 B  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 B  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 B  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 B  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 B  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 B  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 B  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 B  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 B  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 B  952  ALA THR THR
SEQRES   1 C  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 C  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 C  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 C  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 C  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 C  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 C  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 C  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 C  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 C  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 C  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 C  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 C  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 C  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 C  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 C  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 C  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 C  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 C  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 C  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 C  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 C  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 C  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 C  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 C  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 C  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 C  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 C  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 C  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 C  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 C  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 C  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 C  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 C  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 C  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 C  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 C  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 C  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 C  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 C  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 C  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 C  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 C  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 C  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 C  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 C  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 C  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 C  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 C  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 C  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 C  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 C  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 C  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 C  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 C  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 C  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 C  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 C  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 C  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 C  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 C  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 C  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 C  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 C  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 C  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 C  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 C  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 C  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 C  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 C  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 C  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 C  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 C  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 C  952  ALA THR THR
SEQRES   1 D  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 D  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 D  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 D  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 D  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 D  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 D  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 D  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 D  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 D  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 D  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 D  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 D  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 D  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 D  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 D  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 D  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 D  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 D  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 D  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 D  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 D  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 D  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 D  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 D  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 D  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 D  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 D  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 D  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 D  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 D  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 D  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 D  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 D  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 D  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 D  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 D  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 D  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 D  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 D  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 D  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 D  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 D  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 D  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 D  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 D  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 D  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 D  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 D  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 D  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 D  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 D  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 D  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 D  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 D  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 D  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 D  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 D  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 D  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 D  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 D  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 D  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 D  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 D  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 D  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 D  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 D  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 D  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 D  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 D  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 D  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 D  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 D  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 D  952  ALA THR THR
SEQRES   1 E  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 E  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 E  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 E  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 E  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 E  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 E  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 E  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 E  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 E  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 E  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 E  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 E  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 E  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 E  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 E  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 E  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 E  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 E  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 E  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 E  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 E  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 E  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 E  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 E  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 E  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 E  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 E  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 E  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 E  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 E  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 E  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 E  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 E  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 E  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 E  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 E  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 E  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 E  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 E  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 E  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 E  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 E  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 E  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 E  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 E  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 E  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 E  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 E  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 E  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 E  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 E  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 E  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 E  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 E  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 E  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 E  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 E  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 E  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 E  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 E  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 E  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 E  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 E  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 E  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 E  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 E  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 E  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 E  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 E  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 E  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 E  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 E  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 E  952  ALA THR THR
SEQRES   1 F  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 F  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 F  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 F  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 F  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 F  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 F  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 F  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 F  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 F  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 F  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 F  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 F  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 F  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 F  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 F  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 F  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 F  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 F  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 F  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 F  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 F  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 F  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 F  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 F  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 F  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 F  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 F  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 F  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 F  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 F  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 F  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 F  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 F  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 F  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 F  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 F  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 F  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 F  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 F  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 F  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 F  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 F  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 F  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 F  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 F  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 F  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 F  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 F  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 F  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 F  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 F  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 F  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 F  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 F  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 F  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 F  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 F  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 F  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 F  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 F  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 F  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 F  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 F  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 F  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 F  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 F  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 F  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 F  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 F  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 F  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 F  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 F  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 F  952  ALA THR THR
SEQRES   1 G  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 G  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 G  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 G  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 G  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 G  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 G  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 G  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 G  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 G  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 G  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 G  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 G  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 G  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 G  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 G  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 G  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 G  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 G  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 G  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 G  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 G  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 G  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 G  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 G  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 G  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 G  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 G  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 G  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 G  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 G  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 G  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 G  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 G  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 G  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 G  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 G  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 G  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 G  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 G  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 G  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 G  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 G  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 G  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 G  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 G  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 G  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 G  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 G  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 G  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 G  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 G  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 G  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 G  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 G  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 G  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 G  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 G  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 G  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 G  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 G  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 G  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 G  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 G  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 G  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 G  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 G  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 G  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 G  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 G  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 G  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 G  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 G  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 G  952  ALA THR THR
SEQRES   1 H  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 H  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 H  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 H  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 H  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 H  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 H  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 H  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 H  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 H  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 H  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 H  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 H  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 H  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 H  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 H  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 H  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 H  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 H  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 H  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 H  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 H  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 H  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 H  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 H  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 H  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 H  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 H  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 H  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 H  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 H  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 H  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 H  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 H  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 H  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 H  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 H  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 H  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 H  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 H  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 H  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 H  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 H  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 H  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 H  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 H  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 H  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 H  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 H  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 H  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 H  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 H  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 H  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 H  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 H  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 H  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 H  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 H  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 H  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 H  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 H  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 H  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 H  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 H  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 H  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 H  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 H  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 H  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 H  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 H  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 H  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 H  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 H  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 H  952  ALA THR THR
SEQRES   1 I  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 I  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 I  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 I  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 I  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 I  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 I  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 I  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 I  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 I  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 I  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 I  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 I  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 I  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 I  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 I  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 I  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 I  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 I  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 I  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 I  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 I  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 I  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 I  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 I  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 I  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 I  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 I  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 I  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 I  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 I  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 I  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 I  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 I  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 I  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 I  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 I  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 I  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 I  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 I  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 I  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 I  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 I  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 I  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 I  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 I  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 I  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 I  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 I  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 I  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 I  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 I  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 I  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 I  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 I  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 I  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 I  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 I  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 I  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 I  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 I  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 I  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 I  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 I  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 I  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 I  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 I  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 I  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 I  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 I  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 I  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 I  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 I  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 I  952  ALA THR THR
SEQRES   1 J  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 J  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 J  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 J  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 J  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 J  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 J  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 J  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 J  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 J  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 J  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 J  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 J  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 J  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 J  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 J  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 J  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 J  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 J  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 J  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 J  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 J  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 J  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 J  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 J  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 J  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 J  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 J  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 J  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 J  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 J  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 J  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 J  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 J  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 J  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 J  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 J  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 J  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 J  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 J  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 J  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 J  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 J  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 J  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 J  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 J  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 J  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 J  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 J  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 J  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 J  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 J  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 J  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 J  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 J  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 J  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 J  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 J  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 J  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 J  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 J  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 J  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 J  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 J  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 J  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 J  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 J  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 J  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 J  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 J  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 J  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 J  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 J  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 J  952  ALA THR THR
SEQRES   1 K  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 K  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 K  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 K  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 K  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 K  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 K  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 K  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 K  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 K  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 K  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 K  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 K  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 K  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 K  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 K  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 K  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 K  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 K  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 K  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 K  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 K  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 K  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 K  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 K  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 K  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 K  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 K  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 K  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 K  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 K  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 K  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 K  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 K  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 K  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 K  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 K  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 K  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 K  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 K  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 K  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 K  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 K  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 K  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 K  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 K  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 K  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 K  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 K  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 K  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 K  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 K  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 K  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 K  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 K  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 K  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 K  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 K  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 K  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 K  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 K  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 K  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 K  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 K  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 K  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 K  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 K  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 K  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 K  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 K  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 K  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 K  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 K  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 K  952  ALA THR THR
SEQRES   1 L  952  MET ALA THR PRO SER MET MET PRO GLN TRP SER TYR MET
SEQRES   2 L  952  HIS ILE SER GLY GLN ASP ALA SER GLU TYR LEU SER PRO
SEQRES   3 L  952  GLY LEU VAL GLN PHE ALA ARG ALA THR GLU THR TYR PHE
SEQRES   4 L  952  SER LEU ASN ASN LYS PHE ARG ASN PRO THR VAL ALA PRO
SEQRES   5 L  952  THR HIS ASP VAL THR THR ASP ARG SER GLN ARG LEU THR
SEQRES   6 L  952  LEU ARG PHE ILE PRO VAL ASP ARG GLU ASP THR ALA TYR
SEQRES   7 L  952  SER TYR LYS ALA ARG PHE THR LEU ALA VAL GLY ASP ASN
SEQRES   8 L  952  ARG VAL LEU ASP MET ALA SER THR TYR PHE ASP ILE ARG
SEQRES   9 L  952  GLY VAL LEU ASP ARG GLY PRO THR PHE LYS PRO TYR SER
SEQRES  10 L  952  GLY THR ALA TYR ASN ALA LEU ALA PRO LYS GLY ALA PRO
SEQRES  11 L  952  ASN PRO CYS GLU TRP ASP GLU ALA ALA THR ALA LEU GLU
SEQRES  12 L  952  ILE ASN LEU GLU GLU GLU ASP ASP ASP ASN GLU ASP GLU
SEQRES  13 L  952  VAL ASP GLU GLN ALA GLU GLN GLN LYS THR HIS VAL PHE
SEQRES  14 L  952  GLY GLN ALA PRO TYR SER GLY ILE ASN ILE THR LYS GLU
SEQRES  15 L  952  GLY ILE GLN ILE GLY VAL GLU GLY GLN THR PRO LYS TYR
SEQRES  16 L  952  ALA ASP LYS THR PHE GLN PRO GLU PRO GLN ILE GLY GLU
SEQRES  17 L  952  SER GLN TRP TYR GLU THR GLU ILE ASN HIS ALA ALA GLY
SEQRES  18 L  952  ARG VAL LEU LYS LYS THR THR PRO MET LYS PRO CYS TYR
SEQRES  19 L  952  GLY SER TYR ALA LYS PRO THR ASN GLU ASN GLY GLY GLN
SEQRES  20 L  952  GLY ILE LEU VAL LYS GLN GLN ASN GLY LYS LEU GLU SER
SEQRES  21 L  952  GLN VAL GLU MET GLN PHE PHE SER THR THR GLU ALA THR
SEQRES  22 L  952  ALA GLY ASN GLY ASP ASN LEU THR PRO LYS VAL VAL LEU
SEQRES  23 L  952  TYR SER GLU ASP VAL ASP ILE GLU THR PRO ASP THR HIS
SEQRES  24 L  952  ILE SER TYR MET PRO THR ILE LYS GLU GLY ASN SER ARG
SEQRES  25 L  952  GLU LEU MET GLY GLN GLN SER MET PRO ASN ARG PRO ASN
SEQRES  26 L  952  TYR ILE ALA PHE ARG ASP ASN PHE ILE GLY LEU MET TYR
SEQRES  27 L  952  TYR ASN SER THR GLY ASN MET GLY VAL LEU ALA GLY GLN
SEQRES  28 L  952  ALA SER GLN LEU ASN ALA VAL VAL ASP LEU GLN ASP ARG
SEQRES  29 L  952  ASN THR GLU LEU SER TYR GLN LEU LEU LEU ASP SER ILE
SEQRES  30 L  952  GLY ASP ARG THR ARG TYR PHE SER MET TRP ASN GLN ALA
SEQRES  31 L  952  VAL ASP SER TYR ASP PRO ASP VAL ARG ILE ILE GLU ASN
SEQRES  32 L  952  HIS GLY THR GLU ASP GLU LEU PRO ASN TYR CYS PHE PRO
SEQRES  33 L  952  LEU GLY GLY VAL ILE ASN THR GLU THR LEU THR LYS VAL
SEQRES  34 L  952  LYS PRO LYS THR GLY GLN GLU ASN GLY TRP GLU LYS ASP
SEQRES  35 L  952  ALA THR GLU PHE SER ASP LYS ASN GLU ILE ARG VAL GLY
SEQRES  36 L  952  ASN ASN PHE ALA MET GLU ILE ASN LEU ASN ALA ASN LEU
SEQRES  37 L  952  TRP ARG ASN PHE LEU TYR SER ASN ILE ALA LEU TYR LEU
SEQRES  38 L  952  PRO ASP LYS LEU LYS TYR SER PRO SER ASN VAL LYS ILE
SEQRES  39 L  952  SER ASP ASN PRO ASN THR TYR ASP TYR MET ASN LYS ARG
SEQRES  40 L  952  VAL VAL ALA PRO GLY LEU VAL ASP CYS TYR ILE ASN LEU
SEQRES  41 L  952  GLY ALA ARG TRP SER LEU ASP TYR MET ASP ASN VAL ASN
SEQRES  42 L  952  PRO PHE ASN HIS HIS ARG ASN ALA GLY LEU ARG TYR ARG
SEQRES  43 L  952  SER MET LEU LEU GLY ASN GLY ARG TYR VAL PRO PHE HIS
SEQRES  44 L  952  ILE GLN VAL PRO GLN LYS PHE PHE ALA ILE LYS ASN LEU
SEQRES  45 L  952  LEU LEU LEU PRO GLY SER TYR THR TYR GLU TRP ASN PHE
SEQRES  46 L  952  ARG LYS ASP VAL ASN MET VAL LEU GLN SER SER LEU GLY
SEQRES  47 L  952  ASN ASP LEU ARG VAL ASP GLY ALA SER ILE LYS PHE ASP
SEQRES  48 L  952  SER ILE CYS LEU TYR ALA THR PHE PHE PRO MET ALA HIS
SEQRES  49 L  952  ASN THR ALA SER THR LEU GLU ALA MET LEU ARG ASN ASP
SEQRES  50 L  952  THR ASN ASP GLN SER PHE ASN ASP TYR LEU SER ALA ALA
SEQRES  51 L  952  ASN MET LEU TYR PRO ILE PRO ALA ASN ALA THR ASN VAL
SEQRES  52 L  952  PRO ILE SER ILE PRO SER ARG ASN TRP ALA ALA PHE ARG
SEQRES  53 L  952  GLY TRP ALA PHE THR ARG LEU LYS THR LYS GLU THR PRO
SEQRES  54 L  952  SER LEU GLY SER GLY TYR ASP PRO TYR TYR THR TYR SER
SEQRES  55 L  952  GLY SER ILE PRO TYR LEU ASP GLY THR PHE TYR LEU ASN
SEQRES  56 L  952  HIS THR PHE LYS LYS VAL ALA ILE THR PHE ASP SER SER
SEQRES  57 L  952  VAL SER TRP PRO GLY ASN ASP ARG LEU LEU THR PRO ASN
SEQRES  58 L  952  GLU PHE GLU ILE LYS ARG SER VAL ASP GLY GLU GLY TYR
SEQRES  59 L  952  ASN VAL ALA GLN CYS ASN MET THR LYS ASP TRP PHE LEU
SEQRES  60 L  952  VAL GLN MET LEU ALA ASN TYR ASN ILE GLY TYR GLN GLY
SEQRES  61 L  952  PHE TYR ILE PRO GLU SER TYR LYS ASP ARG MET TYR SER
SEQRES  62 L  952  PHE PHE ARG ASN PHE GLN PRO MET SER ARG GLN VAL VAL
SEQRES  63 L  952  ASP ASP THR LYS TYR LYS ASP TYR GLN GLN VAL GLY ILE
SEQRES  64 L  952  LEU HIS GLN HIS ASN ASN SER GLY PHE VAL GLY TYR LEU
SEQRES  65 L  952  ALA PRO THR MET ARG GLU GLY GLN ALA TYR PRO ALA ASN
SEQRES  66 L  952  PHE PRO TYR PRO LEU ILE GLY LYS THR ALA VAL ASP SER
SEQRES  67 L  952  ILE THR GLN LYS LYS PHE LEU CYS ASP ARG THR LEU TRP
SEQRES  68 L  952  ARG ILE PRO PHE SER SER ASN PHE MET SER MET GLY ALA
SEQRES  69 L  952  LEU THR ASP LEU GLY GLN ASN LEU LEU TYR ALA ASN SER
SEQRES  70 L  952  ALA HIS ALA LEU ASP MET THR PHE GLU VAL ASP PRO MET
SEQRES  71 L  952  ASP GLU PRO THR LEU LEU TYR VAL LEU PHE GLU VAL PHE
SEQRES  72 L  952  ASP VAL VAL ARG VAL HIS ARG PRO HIS ARG GLY VAL ILE
SEQRES  73 L  952  GLU THR VAL TYR LEU ARG THR PRO PHE SER ALA GLY ASN
SEQRES  74 L  952  ALA THR THR
SEQRES   1 M  571  MET ARG ARG ALA ALA MET TYR GLU GLU GLY PRO PRO PRO
SEQRES   2 M  571  SER TYR GLU SER VAL VAL SER ALA ALA PRO VAL ALA ALA
SEQRES   3 M  571  ALA LEU GLY SER PRO PHE ASP ALA PRO LEU ASP PRO PRO
SEQRES   4 M  571  PHE VAL PRO PRO ARG TYR LEU ARG PRO THR GLY GLY ARG
SEQRES   5 M  571  ASN SER ILE ARG TYR SER GLU LEU ALA PRO LEU PHE ASP
SEQRES   6 M  571  THR THR ARG VAL TYR LEU VAL ASP ASN LYS SER THR ASP
SEQRES   7 M  571  VAL ALA SER LEU ASN TYR GLN ASN ASP HIS SER ASN PHE
SEQRES   8 M  571  LEU THR THR VAL ILE GLN ASN ASN ASP TYR SER PRO GLY
SEQRES   9 M  571  GLU ALA SER THR GLN THR ILE ASN LEU ASP ASP ARG SER
SEQRES  10 M  571  HIS TRP GLY GLY ASP LEU LYS THR ILE LEU HIS THR ASN
SEQRES  11 M  571  MET PRO ASN VAL ASN GLU PHE MET PHE THR ASN LYS PHE
SEQRES  12 M  571  LYS ALA ARG VAL MET VAL SER ARG LEU PRO THR LYS ASP
SEQRES  13 M  571  ASN GLN VAL GLU LEU LYS TYR GLU TRP VAL GLU PHE THR
SEQRES  14 M  571  LEU PRO GLU GLY ASN TYR SER GLU THR MET THR ILE ASP
SEQRES  15 M  571  LEU MET ASN ASN ALA ILE VAL GLU HIS TYR LEU LYS VAL
SEQRES  16 M  571  GLY ARG GLN ASN GLY VAL LEU GLU SER ASP ILE GLY VAL
SEQRES  17 M  571  LYS PHE ASP THR ARG ASN PHE ARG LEU GLY PHE ASP PRO
SEQRES  18 M  571  VAL THR GLY LEU VAL MET PRO GLY VAL TYR THR ASN GLU
SEQRES  19 M  571  ALA PHE HIS PRO ASP ILE ILE LEU LEU PRO GLY CYS GLY
SEQRES  20 M  571  VAL ASP PHE THR HIS SER ARG LEU SER ASN LEU LEU GLY
SEQRES  21 M  571  ILE ARG LYS ARG GLN PRO PHE GLN GLU GLY PHE ARG ILE
SEQRES  22 M  571  THR TYR ASP ASP LEU GLU GLY GLY ASN ILE PRO ALA LEU
SEQRES  23 M  571  LEU ASP VAL ASP ALA TYR GLN ALA SER LEU LYS ASP ASP
SEQRES  24 M  571  THR GLU GLN GLY GLY GLY GLY ALA GLY GLY SER ASN SER
SEQRES  25 M  571  SER GLY SER GLY ALA GLU GLU ASN SER ASN ALA ALA ALA
SEQRES  26 M  571  ALA ALA MET GLN PRO VAL GLU ASP MET ASN ASP HIS ALA
SEQRES  27 M  571  ILE ARG GLY ASP THR PHE ALA THR ARG ALA GLU GLU LYS
SEQRES  28 M  571  ARG ALA GLU ALA GLU ALA ALA ALA GLU ALA ALA ALA PRO
SEQRES  29 M  571  ALA ALA GLN PRO GLU VAL GLU LYS PRO GLN LYS LYS PRO
SEQRES  30 M  571  VAL ILE LYS PRO LEU THR GLU ASP SER LYS LYS ARG SER
SEQRES  31 M  571  TYR ASN LEU ILE SER ASN ASP SER THR PHE THR GLN TYR
SEQRES  32 M  571  ARG SER TRP TYR LEU ALA TYR ASN TYR GLY ASP PRO GLN
SEQRES  33 M  571  THR GLY ILE ARG SER TRP THR LEU LEU CYS THR PRO ASP
SEQRES  34 M  571  VAL THR CYS GLY SER GLU GLN VAL TYR TRP SER LEU PRO
SEQRES  35 M  571  ASP MET MET GLN ASP PRO VAL THR PHE ARG SER THR ARG
SEQRES  36 M  571  GLN ILE SER ASN PHE PRO VAL VAL GLY ALA GLU LEU LEU
SEQRES  37 M  571  PRO VAL HIS SER LYS SER PHE TYR ASN ASP GLN ALA VAL
SEQRES  38 M  571  TYR SER GLN LEU ILE ARG GLN PHE THR SER LEU THR HIS
SEQRES  39 M  571  VAL PHE ASN ARG PHE PRO GLU ASN GLN ILE LEU ALA ARG
SEQRES  40 M  571  PRO PRO ALA PRO THR ILE THR THR VAL SER GLU ASN VAL
SEQRES  41 M  571  PRO ALA LEU THR ASP HIS GLY THR LEU PRO LEU ARG ASN
SEQRES  42 M  571  SER ILE GLY GLY VAL GLN ARG VAL THR ILE THR ASP ALA
SEQRES  43 M  571  ARG ARG ARG THR CYS PRO TYR VAL TYR LYS ALA LEU GLY
SEQRES  44 M  571  ILE VAL SER PRO ARG VAL LEU SER SER ARG THR PHE
SEQRES   1 N  585  MET MET GLN ASP ALA THR ASP PRO ALA VAL ARG ALA ALA
SEQRES   2 N  585  LEU GLN SER GLN PRO SER GLY LEU ASN SER THR ASP ASP
SEQRES   3 N  585  TRP ARG GLN VAL MET ASP ARG ILE MET SER LEU THR ALA
SEQRES   4 N  585  ARG ASN PRO ASP ALA PHE ARG GLN GLN PRO GLN ALA ASN
SEQRES   5 N  585  ARG LEU SER ALA ILE LEU GLU ALA VAL VAL PRO ALA ARG
SEQRES   6 N  585  ALA ASN PRO THR HIS GLU LYS VAL LEU ALA ILE VAL ASN
SEQRES   7 N  585  ALA LEU ALA GLU ASN ARG ALA ILE ARG PRO ASP GLU ALA
SEQRES   8 N  585  GLY LEU VAL TYR ASP ALA LEU LEU GLN ARG VAL ALA ARG
SEQRES   9 N  585  TYR ASN SER GLY ASN VAL GLN THR ASN LEU ASP ARG LEU
SEQRES  10 N  585  VAL GLY ASP VAL ARG GLU ALA VAL ALA GLN ARG GLU ARG
SEQRES  11 N  585  ALA GLN GLN GLN GLY ASN LEU GLY SER MET VAL ALA LEU
SEQRES  12 N  585  ASN ALA PHE LEU SER THR GLN PRO ALA ASN VAL PRO ARG
SEQRES  13 N  585  GLY GLN GLU ASP TYR THR ASN PHE VAL SER ALA LEU ARG
SEQRES  14 N  585  LEU MET VAL THR GLU THR PRO GLN SER GLU VAL TYR GLN
SEQRES  15 N  585  SER GLY PRO ASP TYR PHE PHE GLN THR SER ARG GLN GLY
SEQRES  16 N  585  LEU GLN THR VAL ASN LEU SER GLN ALA PHE LYS ASN LEU
SEQRES  17 N  585  GLN GLY LEU TRP GLY VAL ARG ALA PRO THR GLY ASP ARG
SEQRES  18 N  585  ALA THR VAL SER SER LEU LEU THR PRO ASN SER ARG LEU
SEQRES  19 N  585  LEU LEU LEU LEU ILE ALA PRO PHE THR ASP SER GLY SER
SEQRES  20 N  585  VAL SER ARG ASP THR TYR LEU GLY HIS LEU LEU THR LEU
SEQRES  21 N  585  TYR ARG GLU ALA ILE GLY GLN ALA HIS VAL ASP GLU HIS
SEQRES  22 N  585  THR PHE GLN GLU ILE THR SER VAL SER ARG ALA LEU GLY
SEQRES  23 N  585  GLN GLU ASP THR GLY SER LEU GLU ALA THR LEU ASN TYR
SEQRES  24 N  585  LEU LEU THR ASN ARG ARG GLN LYS ILE PRO SER LEU HIS
SEQRES  25 N  585  SER LEU ASN SER GLU GLU GLU ARG ILE LEU ARG TYR VAL
SEQRES  26 N  585  GLN GLN SER VAL SER LEU ASN LEU MET ARG ASP GLY VAL
SEQRES  27 N  585  THR PRO SER VAL ALA LEU ASP MET THR ALA ARG ASN MET
SEQRES  28 N  585  GLU PRO GLY MET TYR ALA SER ASN ARG PRO PHE ILE ASN
SEQRES  29 N  585  ARG LEU MET ASP TYR LEU HIS ARG ALA ALA ALA VAL ASN
SEQRES  30 N  585  PRO GLU TYR PHE THR ASN ALA ILE LEU ASN PRO HIS TRP
SEQRES  31 N  585  LEU PRO PRO PRO GLY PHE TYR THR GLY GLY PHE GLU VAL
SEQRES  32 N  585  PRO GLU GLY ASN ASP GLY PHE LEU TRP ASP ASP ILE ASP
SEQRES  33 N  585  ASP SER VAL PHE SER PRO GLN PRO GLN THR LEU LEU GLU
SEQRES  34 N  585  LEU GLN GLN ARG GLU GLN ALA GLU ALA ALA LEU ARG LYS
SEQRES  35 N  585  GLU SER PHE ARG ARG PRO SER SER LEU SER ASP LEU GLY
SEQRES  36 N  585  ALA ALA ALA PRO ARG SER ASP ALA SER SER PRO PHE PRO
SEQRES  37 N  585  SER LEU ILE GLY SER LEU THR SER THR ARG THR THR ARG
SEQRES  38 N  585  PRO ARG LEU LEU GLY GLU GLU GLU TYR LEU ASN ASN SER
SEQRES  39 N  585  LEU LEU GLN PRO GLN ARG GLU LYS ASN LEU PRO PRO ALA
SEQRES  40 N  585  PHE PRO ASN ASN GLY ILE GLU SER LEU VAL ASP LYS MET
SEQRES  41 N  585  SER ARG TRP LYS THR TYR ALA GLN GLU HIS ARG ASP VAL
SEQRES  42 N  585  PRO GLY PRO ARG PRO PRO THR ARG ARG GLN ARG HIS ASP
SEQRES  43 N  585  ARG GLN ARG GLY LEU VAL TRP GLU ASP ASP ASP SER ALA
SEQRES  44 N  585  ASP ASP SER SER VAL LEU ASP LEU GLY GLY SER GLY ASN
SEQRES  45 N  585  PRO PHE ALA HIS LEU ARG PRO ARG LEU GLY ARG MET PHE
SEQRES   1 O  227  MET SER LYS GLU ILE PRO THR PRO TYR MET TRP SER TYR
SEQRES   2 O  227  GLN PRO GLN MET GLY LEU ALA ALA GLY ALA ALA GLN ASP
SEQRES   3 O  227  TYR SER THR ARG ILE ASN TYR MET SER ALA GLY PRO HIS
SEQRES   4 O  227  MET ILE SER ARG VAL ASN GLY ILE ARG ALA HIS ARG ASN
SEQRES   5 O  227  ARG ILE LEU LEU GLU GLN ALA ALA ILE THR THR THR PRO
SEQRES   6 O  227  ARG ASN ASN LEU ASN PRO ARG SER TRP PRO ALA ALA LEU
SEQRES   7 O  227  VAL TYR GLN GLU SER PRO ALA PRO THR THR VAL VAL LEU
SEQRES   8 O  227  PRO ARG ASP ALA GLN ALA GLU VAL GLN MET THR ASN SER
SEQRES   9 O  227  GLY ALA GLN LEU ALA GLY GLY PHE ARG HIS ARG VAL ARG
SEQRES  10 O  227  SER PRO GLY GLN GLY ILE THR HIS LEU THR ILE ARG GLY
SEQRES  11 O  227  ARG GLY ILE GLN LEU ASN ASP GLU SER VAL SER SER SER
SEQRES  12 O  227  LEU GLY LEU ARG PRO ASP GLY THR PHE GLN ILE GLY GLY
SEQRES  13 O  227  ALA GLY ARG PRO SER PHE THR PRO ARG GLN ALA ILE LEU
SEQRES  14 O  227  THR LEU GLN THR SER SER SER GLU PRO ARG SER GLY GLY
SEQRES  15 O  227  ILE GLY THR LEU GLN PHE ILE GLU GLU PHE VAL PRO SER
SEQRES  16 O  227  VAL TYR PHE ASN PRO PHE SER GLY PRO PRO GLY HIS TYR
SEQRES  17 O  227  PRO ASP GLN PHE ILE PRO ASN PHE ASP ALA VAL LYS ASP
SEQRES  18 O  227  SER ALA ASP GLY TYR ASP
SEQRES   1 P  227  MET SER LYS GLU ILE PRO THR PRO TYR MET TRP SER TYR
SEQRES   2 P  227  GLN PRO GLN MET GLY LEU ALA ALA GLY ALA ALA GLN ASP
SEQRES   3 P  227  TYR SER THR ARG ILE ASN TYR MET SER ALA GLY PRO HIS
SEQRES   4 P  227  MET ILE SER ARG VAL ASN GLY ILE ARG ALA HIS ARG ASN
SEQRES   5 P  227  ARG ILE LEU LEU GLU GLN ALA ALA ILE THR THR THR PRO
SEQRES   6 P  227  ARG ASN ASN LEU ASN PRO ARG SER TRP PRO ALA ALA LEU
SEQRES   7 P  227  VAL TYR GLN GLU SER PRO ALA PRO THR THR VAL VAL LEU
SEQRES   8 P  227  PRO ARG ASP ALA GLN ALA GLU VAL GLN MET THR ASN SER
SEQRES   9 P  227  GLY ALA GLN LEU ALA GLY GLY PHE ARG HIS ARG VAL ARG
SEQRES  10 P  227  SER PRO GLY GLN GLY ILE THR HIS LEU THR ILE ARG GLY
SEQRES  11 P  227  ARG GLY ILE GLN LEU ASN ASP GLU SER VAL SER SER SER
SEQRES  12 P  227  LEU GLY LEU ARG PRO ASP GLY THR PHE GLN ILE GLY GLY
SEQRES  13 P  227  ALA GLY ARG PRO SER PHE THR PRO ARG GLN ALA ILE LEU
SEQRES  14 P  227  THR LEU GLN THR SER SER SER GLU PRO ARG SER GLY GLY
SEQRES  15 P  227  ILE GLY THR LEU GLN PHE ILE GLU GLU PHE VAL PRO SER
SEQRES  16 P  227  VAL TYR PHE ASN PRO PHE SER GLY PRO PRO GLY HIS TYR
SEQRES  17 P  227  PRO ASP GLN PHE ILE PRO ASN PHE ASP ALA VAL LYS ASP
SEQRES  18 P  227  SER ALA ASP GLY TYR ASP
SEQRES   1 Q  140  MET SER THR ASN SER PHE ASP GLY SER ILE VAL SER SER
SEQRES   2 Q  140  TYR LEU THR THR ARG MET PRO PRO TRP ALA GLY VAL ARG
SEQRES   3 Q  140  GLN ASN VAL MET GLY SER SER ILE ASP GLY ARG PRO VAL
SEQRES   4 Q  140  LEU PRO ALA ASN SER THR THR LEU THR TYR GLU THR VAL
SEQRES   5 Q  140  SER GLY THR PRO LEU GLU THR ALA ALA SER ALA ALA ALA
SEQRES   6 Q  140  SER ALA ALA ALA ALA THR ALA ARG GLY ILE VAL THR ASP
SEQRES   7 Q  140  PHE ALA PHE LEU SER PRO LEU ALA SER SER ALA ALA SER
SEQRES   8 Q  140  ARG SER SER ALA ARG ASP ASP LYS LEU THR ALA LEU LEU
SEQRES   9 Q  140  ALA GLN LEU ASP SER LEU THR ARG GLU LEU ASN VAL VAL
SEQRES  10 Q  140  SER GLN GLN LEU LEU ASP LEU ARG GLN GLN VAL SER ALA
SEQRES  11 Q  140  LEU LYS ALA SER SER PRO PRO ASN ALA VAL
SEQRES   1 R  140  MET SER THR ASN SER PHE ASP GLY SER ILE VAL SER SER
SEQRES   2 R  140  TYR LEU THR THR ARG MET PRO PRO TRP ALA GLY VAL ARG
SEQRES   3 R  140  GLN ASN VAL MET GLY SER SER ILE ASP GLY ARG PRO VAL
SEQRES   4 R  140  LEU PRO ALA ASN SER THR THR LEU THR TYR GLU THR VAL
SEQRES   5 R  140  SER GLY THR PRO LEU GLU THR ALA ALA SER ALA ALA ALA
SEQRES   6 R  140  SER ALA ALA ALA ALA THR ALA ARG GLY ILE VAL THR ASP
SEQRES   7 R  140  PHE ALA PHE LEU SER PRO LEU ALA SER SER ALA ALA SER
SEQRES   8 R  140  ARG SER SER ALA ARG ASP ASP LYS LEU THR ALA LEU LEU
SEQRES   9 R  140  ALA GLN LEU ASP SER LEU THR ARG GLU LEU ASN VAL VAL
SEQRES  10 R  140  SER GLN GLN LEU LEU ASP LEU ARG GLN GLN VAL SER ALA
SEQRES  11 R  140  LEU LYS ALA SER SER PRO PRO ASN ALA VAL
SEQRES   1 S  140  MET SER THR ASN SER PHE ASP GLY SER ILE VAL SER SER
SEQRES   2 S  140  TYR LEU THR THR ARG MET PRO PRO TRP ALA GLY VAL ARG
SEQRES   3 S  140  GLN ASN VAL MET GLY SER SER ILE ASP GLY ARG PRO VAL
SEQRES   4 S  140  LEU PRO ALA ASN SER THR THR LEU THR TYR GLU THR VAL
SEQRES   5 S  140  SER GLY THR PRO LEU GLU THR ALA ALA SER ALA ALA ALA
SEQRES   6 S  140  SER ALA ALA ALA ALA THR ALA ARG GLY ILE VAL THR ASP
SEQRES   7 S  140  PHE ALA PHE LEU SER PRO LEU ALA SER SER ALA ALA SER
SEQRES   8 S  140  ARG SER SER ALA ARG ASP ASP LYS LEU THR ALA LEU LEU
SEQRES   9 S  140  ALA GLN LEU ASP SER LEU THR ARG GLU LEU ASN VAL VAL
SEQRES  10 S  140  SER GLN GLN LEU LEU ASP LEU ARG GLN GLN VAL SER ALA
SEQRES  11 S  140  LEU LYS ALA SER SER PRO PRO ASN ALA VAL
SEQRES   1 T  140  MET SER THR ASN SER PHE ASP GLY SER ILE VAL SER SER
SEQRES   2 T  140  TYR LEU THR THR ARG MET PRO PRO TRP ALA GLY VAL ARG
SEQRES   3 T  140  GLN ASN VAL MET GLY SER SER ILE ASP GLY ARG PRO VAL
SEQRES   4 T  140  LEU PRO ALA ASN SER THR THR LEU THR TYR GLU THR VAL
SEQRES   5 T  140  SER GLY THR PRO LEU GLU THR ALA ALA SER ALA ALA ALA
SEQRES   6 T  140  SER ALA ALA ALA ALA THR ALA ARG GLY ILE VAL THR ASP
SEQRES   7 T  140  PHE ALA PHE LEU SER PRO LEU ALA SER SER ALA ALA SER
SEQRES   8 T  140  ARG SER SER ALA ARG ASP ASP LYS LEU THR ALA LEU LEU
SEQRES   9 T  140  ALA GLN LEU ASP SER LEU THR ARG GLU LEU ASN VAL VAL
SEQRES  10 T  140  SER GLN GLN LEU LEU ASP LEU ARG GLN GLN VAL SER ALA
SEQRES  11 T  140  LEU LYS ALA SER SER PRO PRO ASN ALA VAL
HELIX    1   1 PRO A    7  MET A   12  1                                   6
HELIX    2   2 ALA A   19  TYR A   22  1                                   4
HELIX    3   3 PRO A   25  ALA A   33  1                                   9
HELIX    4   4 ASN A   41  LYS A   43  1                                   3
HELIX    5   5 MET A   95  SER A   97  1                                   3
HELIX    6   6 ARG A  311  GLY A  315  1                                   5
HELIX    7   7 ASP A  330  PHE A  332  1                                   3
HELIX    8   8 THR A  341  ASN A  343  1                                   3
HELIX    9   9 THR A  365  ILE A  376  1                                  12
HELIX   10  10 SER A  384  TRP A  386  1                                   3
HELIX   11  11 PRO A  395  ARG A  398  1                                   4
HELIX   12  12 LEU A  463  TYR A  479  1                                  17
HELIX   13  13 ASP A  482  LEU A  484  1                                   3
HELIX   14  14 TYR A  500  LYS A  505  1                                   6
HELIX   15  15 PRO A  510  VAL A  513  1                                   4
HELIX   16  16 ASP A  526  ASP A  529  1                                   4
HELIX   17  17 ALA A  540  LEU A  549  1                                  10
HELIX   18  18 VAL A  588  VAL A  591  1                                   4
HELIX   19  19 HIS A  623  ARG A  634  1                                  12
HELIX   20  20 ASP A  636  ASN A  638  1                                   3
HELIX   21  21 THR A  684  GLU A  686  1                                   3
HELIX   22  22 PRO A  705  ASP A  708  1                                   4
HELIX   23  23 ASN A  714  THR A  716  1                                   3
HELIX   24  24 LYS A  762  TYR A  773  1                                  12
HELIX   25  25 SER A  785  LYS A  787  1                                   3
HELIX   26  26 PHE A  793  ASN A  796  1                                   4
HELIX   27  27 ILE A  818  HIS A  820  1                                   3
HELIX   28  28 LEU A  887  GLN A  889  1                                   3
HELIX   29  29 LEU A  891  ASN A  895  1                                   5
HELIX   30  30 PRO B    7  MET B   12  1                                   6
HELIX   31  31 ALA B   19  TYR B   22  1                                   4
HELIX   32  32 PRO B   25  ALA B   33  1                                   9
HELIX   33  33 ASN B   41  LYS B   43  1                                   3
HELIX   34  34 MET B   95  SER B   97  1                                   3
HELIX   35  35 ARG B  311  GLY B  315  1                                   5
HELIX   36  36 ASP B  330  PHE B  332  1                                   3
HELIX   37  37 THR B  341  ASN B  343  1                                   3
HELIX   38  38 THR B  365  ILE B  376  1                                  12
HELIX   39  39 SER B  384  TRP B  386  1                                   3
HELIX   40  40 PRO B  395  ARG B  398  1                                   4
HELIX   41  41 LEU B  463  TYR B  479  1                                  17
HELIX   42  42 ASP B  482  LEU B  484  1                                   3
HELIX   43  43 TYR B  500  LYS B  505  1                                   6
HELIX   44  44 PRO B  510  VAL B  513  1                                   4
HELIX   45  45 ASP B  526  ASP B  529  1                                   4
HELIX   46  46 ALA B  540  LEU B  549  1                                  10
HELIX   47  47 VAL B  588  VAL B  591  1                                   4
HELIX   48  48 HIS B  623  ARG B  634  1                                  12
HELIX   49  49 ASP B  636  ASN B  638  1                                   3
HELIX   50  50 THR B  684  GLU B  686  1                                   3
HELIX   51  51 PRO B  705  ASP B  708  1                                   4
HELIX   52  52 ASN B  714  THR B  716  1                                   3
HELIX   53  53 LYS B  762  TYR B  773  1                                  12
HELIX   54  54 SER B  785  LYS B  787  1                                   3
HELIX   55  55 PHE B  793  ASN B  796  1                                   4
HELIX   56  56 ILE B  818  HIS B  820  1                                   3
HELIX   57  57 LEU B  887  GLN B  889  1                                   3
HELIX   58  58 LEU B  891  ASN B  895  1                                   5
HELIX   59  59 GLN C    8  HIS C   13  1                                   6
HELIX   60  60 ALA C   19  TYR C   22  1                                   4
HELIX   61  61 PRO C   25  ALA C   33  1                                   9
HELIX   62  62 ASN C   41  LYS C   43  1                                   3
HELIX   63  63 MET C   95  SER C   97  1                                   3
HELIX   64  64 ARG C  311  GLY C  315  1                                   5
HELIX   65  65 ASP C  330  PHE C  332  1                                   3
HELIX   66  66 THR C  341  ASN C  343  1                                   3
HELIX   67  67 THR C  365  ILE C  376  1                                  12
HELIX   68  68 SER C  384  TRP C  386  1                                   3
HELIX   69  69 PRO C  395  ARG C  398  1                                   4
HELIX   70  70 LEU C  463  TYR C  479  1                                  17
HELIX   71  71 ASP C  482  LEU C  484  1                                   3
HELIX   72  72 TYR C  500  LYS C  505  1                                   6
HELIX   73  73 PRO C  510  VAL C  513  1                                   4
HELIX   74  74 ASP C  526  ASP C  529  1                                   4
HELIX   75  75 ALA C  540  LEU C  549  1                                  10
HELIX   76  76 VAL C  588  VAL C  591  1                                   4
HELIX   77  77 HIS C  623  ARG C  634  1                                  12
HELIX   78  78 ASP C  636  ASN C  638  1                                   3
HELIX   79  79 THR C  684  GLU C  686  1                                   3
HELIX   80  80 PRO C  705  ASP C  708  1                                   4
HELIX   81  81 ASN C  714  THR C  716  1                                   3
HELIX   82  82 LYS C  762  TYR C  773  1                                  12
HELIX   83  83 SER C  785  LYS C  787  1                                   3
HELIX   84  84 PHE C  793  ASN C  796  1                                   4
HELIX   85  85 ILE C  818  HIS C  820  1                                   3
HELIX   86  86 LEU C  887  GLN C  889  1                                   3
HELIX   87  87 LEU C  891  ASN C  895  1                                   5
HELIX   88  88 PRO D    7  MET D   12  1                                   6
HELIX   89  89 ALA D   19  TYR D   22  1                                   4
HELIX   90  90 PRO D   25  ALA D   33  1                                   9
HELIX   91  91 ASN D   41  LYS D   43  1                                   3
HELIX   92  92 MET D   95  SER D   97  1                                   3
HELIX   93  93 ARG D  311  GLY D  315  1                                   5
HELIX   94  94 ASP D  330  PHE D  332  1                                   3
HELIX   95  95 THR D  341  ASN D  343  1                                   3
HELIX   96  96 THR D  365  ILE D  376  1                                  12
HELIX   97  97 SER D  384  TRP D  386  1                                   3
HELIX   98  98 PRO D  395  ARG D  398  1                                   4
HELIX   99  99 LEU D  463  TYR D  479  1                                  17
HELIX  100 100 ASP D  482  LEU D  484  1                                   3
HELIX  101 101 TYR D  500  LYS D  505  1                                   6
HELIX  102 102 PRO D  510  VAL D  513  1                                   4
HELIX  103 103 ASP D  526  ASP D  529  1                                   4
HELIX  104 104 ALA D  540  LEU D  549  1                                  10
HELIX  105 105 VAL D  588  VAL D  591  1                                   4
HELIX  106 106 HIS D  623  ARG D  634  1                                  12
HELIX  107 107 ASP D  636  ASN D  638  1                                   3
HELIX  108 108 THR D  684  GLU D  686  1                                   3
HELIX  109 109 PRO D  705  ASP D  708  1                                   4
HELIX  110 110 ASN D  714  THR D  716  1                                   3
HELIX  111 111 LYS D  762  TYR D  773  1                                  12
HELIX  112 112 SER D  785  LYS D  787  1                                   3
HELIX  113 113 PHE D  793  ASN D  796  1                                   4
HELIX  114 114 ILE D  818  HIS D  820  1                                   3
HELIX  115 115 LEU D  887  GLN D  889  1                                   3
HELIX  116 116 LEU D  891  ASN D  895  1                                   5
HELIX  117 117 PRO E    7  MET E   12  1                                   6
HELIX  118 118 ALA E   19  TYR E   22  1                                   4
HELIX  119 119 PRO E   25  ALA E   33  1                                   9
HELIX  120 120 ASN E   41  LYS E   43  1                                   3
HELIX  121 121 MET E   95  SER E   97  1                                   3
HELIX  122 122 ARG E  311  GLY E  315  1                                   5
HELIX  123 123 ASP E  330  PHE E  332  1                                   3
HELIX  124 124 THR E  341  ASN E  343  1                                   3
HELIX  125 125 THR E  365  ILE E  376  1                                  12
HELIX  126 126 SER E  384  TRP E  386  1                                   3
HELIX  127 127 PRO E  395  ARG E  398  1                                   4
HELIX  128 128 LEU E  463  TYR E  479  1                                  17
HELIX  129 129 ASP E  482  LEU E  484  1                                   3
HELIX  130 130 TYR E  500  LYS E  505  1                                   6
HELIX  131 131 PRO E  510  VAL E  513  1                                   4
HELIX  132 132 ASP E  526  ASP E  529  1                                   4
HELIX  133 133 ALA E  540  LEU E  549  1                                  10
HELIX  134 134 VAL E  588  VAL E  591  1                                   4
HELIX  135 135 HIS E  623  ARG E  634  1                                  12
HELIX  136 136 ASP E  636  ASN E  638  1                                   3
HELIX  137 137 THR E  684  GLU E  686  1                                   3
HELIX  138 138 PRO E  705  ASP E  708  1                                   4
HELIX  139 139 ASN E  714  THR E  716  1                                   3
HELIX  140 140 LYS E  762  TYR E  773  1                                  12
HELIX  141 141 SER E  785  LYS E  787  1                                   3
HELIX  142 142 PHE E  793  ASN E  796  1                                   4
HELIX  143 143 ILE E  818  HIS E  820  1                                   3
HELIX  144 144 LEU E  887  GLN E  889  1                                   3
HELIX  145 145 LEU E  891  ASN E  895  1                                   5
HELIX  146 146 PRO F    7  MET F   12  1                                   6
HELIX  147 147 ALA F   19  TYR F   22  1                                   4
HELIX  148 148 PRO F   25  ALA F   33  1                                   9
HELIX  149 149 ASN F   41  LYS F   43  1                                   3
HELIX  150 150 MET F   95  SER F   97  1                                   3
HELIX  151 151 ARG F  311  GLY F  315  1                                   5
HELIX  152 152 ASP F  330  PHE F  332  1                                   3
HELIX  153 153 THR F  341  ASN F  343  1                                   3
HELIX  154 154 THR F  365  ILE F  376  1                                  12
HELIX  155 155 SER F  384  TRP F  386  1                                   3
HELIX  156 156 PRO F  395  ARG F  398  1                                   4
HELIX  157 157 LEU F  463  TYR F  479  1                                  17
HELIX  158 158 ASP F  482  LEU F  484  1                                   3
HELIX  159 159 TYR F  500  LYS F  505  1                                   6
HELIX  160 160 PRO F  510  VAL F  513  1                                   4
HELIX  161 161 ASP F  526  ASP F  529  1                                   4
HELIX  162 162 ALA F  540  LEU F  549  1                                  10
HELIX  163 163 VAL F  588  VAL F  591  1                                   4
HELIX  164 164 HIS F  623  ARG F  634  1                                  12
HELIX  165 165 ASP F  636  ASN F  638  1                                   3
HELIX  166 166 THR F  684  GLU F  686  1                                   3
HELIX  167 167 PRO F  705  ASP F  708  1                                   4
HELIX  168 168 ASN F  714  THR F  716  1                                   3
HELIX  169 169 LYS F  762  TYR F  773  1                                  12
HELIX  170 170 SER F  785  LYS F  787  1                                   3
HELIX  171 171 PHE F  793  ASN F  796  1                                   4
HELIX  172 172 ILE F  818  HIS F  820  1                                   3
HELIX  173 173 LEU F  887  GLN F  889  1                                   3
HELIX  174 174 LEU F  891  ASN F  895  1                                   5
HELIX  175 175 PRO G    7  MET G   12  1                                   6
HELIX  176 176 ALA G   19  TYR G   22  1                                   4
HELIX  177 177 PRO G   25  ALA G   33  1                                   9
HELIX  178 178 ASN G   41  LYS G   43  1                                   3
HELIX  179 179 MET G   95  SER G   97  1                                   3
HELIX  180 180 ARG G  311  GLY G  315  1                                   5
HELIX  181 181 ASP G  330  PHE G  332  1                                   3
HELIX  182 182 THR G  341  ASN G  343  1                                   3
HELIX  183 183 THR G  365  ILE G  376  1                                  12
HELIX  184 184 SER G  384  TRP G  386  1                                   3
HELIX  185 185 PRO G  395  ARG G  398  1                                   4
HELIX  186 186 LEU G  463  TYR G  479  1                                  17
HELIX  187 187 ASP G  482  LEU G  484  1                                   3
HELIX  188 188 TYR G  500  LYS G  505  1                                   6
HELIX  189 189 PRO G  510  VAL G  513  1                                   4
HELIX  190 190 ASP G  526  ASP G  529  1                                   4
HELIX  191 191 ALA G  540  LEU G  549  1                                  10
HELIX  192 192 VAL G  588  VAL G  591  1                                   4
HELIX  193 193 HIS G  623  ARG G  634  1                                  12
HELIX  194 194 ASP G  636  ASN G  638  1                                   3
HELIX  195 195 THR G  684  GLU G  686  1                                   3
HELIX  196 196 PRO G  705  ASP G  708  1                                   4
HELIX  197 197 ASN G  714  THR G  716  1                                   3
HELIX  198 198 LYS G  762  TYR G  773  1                                  12
HELIX  199 199 SER G  785  LYS G  787  1                                   3
HELIX  200 200 PHE G  793  ASN G  796  1                                   4
HELIX  201 201 ILE G  818  HIS G  820  1                                   3
HELIX  202 202 LEU G  887  GLN G  889  1                                   3
HELIX  203 203 LEU G  891  ASN G  895  1                                   5
HELIX  204 204 MET H    6  MET H   12  1                                   7
HELIX  205 205 ALA H   19  TYR H   22  1                                   4
HELIX  206 206 PRO H   25  ALA H   33  1                                   9
HELIX  207 207 ASN H   41  LYS H   43  1                                   3
HELIX  208 208 MET H   95  SER H   97  1                                   3
HELIX  209 209 ARG H  311  GLY H  315  1                                   5
HELIX  210 210 ASP H  330  PHE H  332  1                                   3
HELIX  211 211 THR H  341  ASN H  343  1                                   3
HELIX  212 212 THR H  365  ILE H  376  1                                  12
HELIX  213 213 SER H  384  TRP H  386  1                                   3
HELIX  214 214 PRO H  395  ARG H  398  1                                   4
HELIX  215 215 LEU H  463  TYR H  479  1                                  17
HELIX  216 216 ASP H  482  LEU H  484  1                                   3
HELIX  217 217 TYR H  500  LYS H  505  1                                   6
HELIX  218 218 PRO H  510  VAL H  513  1                                   4
HELIX  219 219 ASP H  526  ASP H  529  1                                   4
HELIX  220 220 ALA H  540  LEU H  549  1                                  10
HELIX  221 221 VAL H  588  VAL H  591  1                                   4
HELIX  222 222 HIS H  623  ARG H  634  1                                  12
HELIX  223 223 ASP H  636  ASN H  638  1                                   3
HELIX  224 224 THR H  684  GLU H  686  1                                   3
HELIX  225 225 PRO H  705  ASP H  708  1                                   4
HELIX  226 226 ASN H  714  THR H  716  1                                   3
HELIX  227 227 LYS H  762  TYR H  773  1                                  12
HELIX  228 228 SER H  785  LYS H  787  1                                   3
HELIX  229 229 PHE H  793  ASN H  796  1                                   4
HELIX  230 230 ILE H  818  HIS H  820  1                                   3
HELIX  231 231 LEU H  887  GLN H  889  1                                   3
HELIX  232 232 LEU H  891  ASN H  895  1                                   5
HELIX  233 233 PRO I    7  MET I   12  1                                   6
HELIX  234 234 ALA I   19  TYR I   22  1                                   4
HELIX  235 235 PRO I   25  ALA I   33  1                                   9
HELIX  236 236 ASN I   41  LYS I   43  1                                   3
HELIX  237 237 MET I   95  SER I   97  1                                   3
HELIX  238 238 ARG I  311  GLY I  315  1                                   5
HELIX  239 239 ASP I  330  PHE I  332  1                                   3
HELIX  240 240 THR I  341  ASN I  343  1                                   3
HELIX  241 241 THR I  365  ILE I  376  1                                  12
HELIX  242 242 SER I  384  TRP I  386  1                                   3
HELIX  243 243 PRO I  395  ARG I  398  1                                   4
HELIX  244 244 LEU I  463  TYR I  479  1                                  17
HELIX  245 245 ASP I  482  LEU I  484  1                                   3
HELIX  246 246 TYR I  500  LYS I  505  1                                   6
HELIX  247 247 PRO I  510  VAL I  513  1                                   4
HELIX  248 248 ASP I  526  ASP I  529  1                                   4
HELIX  249 249 ALA I  540  LEU I  549  1                                  10
HELIX  250 250 VAL I  588  VAL I  591  1                                   4
HELIX  251 251 HIS I  623  ARG I  634  1                                  12
HELIX  252 252 ASP I  636  ASN I  638  1                                   3
HELIX  253 253 THR I  684  GLU I  686  1                                   3
HELIX  254 254 PRO I  705  ASP I  708  1                                   4
HELIX  255 255 ASN I  714  THR I  716  1                                   3
HELIX  256 256 LYS I  762  TYR I  773  1                                  12
HELIX  257 257 SER I  785  LYS I  787  1                                   3
HELIX  258 258 PHE I  793  ASN I  796  1                                   4
HELIX  259 259 ILE I  818  HIS I  820  1                                   3
HELIX  260 260 LEU I  887  GLN I  889  1                                   3
HELIX  261 261 LEU I  891  ASN I  895  1                                   5
HELIX  262 262 PRO J    7  MET J   12  1                                   6
HELIX  263 263 ALA J   19  TYR J   22  1                                   4
HELIX  264 264 PRO J   25  ALA J   33  1                                   9
HELIX  265 265 ASN J   41  LYS J   43  1                                   3
HELIX  266 266 MET J   95  SER J   97  1                                   3
HELIX  267 267 ARG J  311  GLY J  315  1                                   5
HELIX  268 268 ASP J  330  PHE J  332  1                                   3
HELIX  269 269 THR J  341  ASN J  343  1                                   3
HELIX  270 270 THR J  365  ILE J  376  1                                  12
HELIX  271 271 SER J  384  TRP J  386  1                                   3
HELIX  272 272 PRO J  395  ARG J  398  1                                   4
HELIX  273 273 LEU J  463  TYR J  479  1                                  17
HELIX  274 274 ASP J  482  LEU J  484  1                                   3
HELIX  275 275 TYR J  500  LYS J  505  1                                   6
HELIX  276 276 PRO J  510  VAL J  513  1                                   4
HELIX  277 277 ASP J  526  ASP J  529  1                                   4
HELIX  278 278 ALA J  540  LEU J  549  1                                  10
HELIX  279 279 VAL J  588  VAL J  591  1                                   4
HELIX  280 280 HIS J  623  ARG J  634  1                                  12
HELIX  281 281 ASP J  636  ASN J  638  1                                   3
HELIX  282 282 THR J  684  GLU J  686  1                                   3
HELIX  283 283 PRO J  705  ASP J  708  1                                   4
HELIX  284 284 ASN J  714  THR J  716  1                                   3
HELIX  285 285 LYS J  762  TYR J  773  1                                  12
HELIX  286 286 SER J  785  LYS J  787  1                                   3
HELIX  287 287 PHE J  793  ASN J  796  1                                   4
HELIX  288 288 ILE J  818  HIS J  820  1                                   3
HELIX  289 289 LEU J  887  GLN J  889  1                                   3
HELIX  290 290 GLN K    8  TYR K   11  1                                   4
HELIX  291 291 ALA K   19  TYR K   22  1                                   4
HELIX  292 292 PRO K   25  ALA K   33  1                                   9
HELIX  293 293 ASN K   41  LYS K   43  1                                   3
HELIX  294 294 MET K   95  SER K   97  1                                   3
HELIX  295 295 ARG K  311  GLY K  315  1                                   5
HELIX  296 296 ASP K  330  PHE K  332  1                                   3
HELIX  297 297 THR K  341  ASN K  343  1                                   3
HELIX  298 298 THR K  365  ILE K  376  1                                  12
HELIX  299 299 SER K  384  TRP K  386  1                                   3
HELIX  300 300 PRO K  395  ARG K  398  1                                   4
HELIX  301 301 LEU K  463  TYR K  479  1                                  17
HELIX  302 302 ASP K  482  LEU K  484  1                                   3
HELIX  303 303 TYR K  500  LYS K  505  1                                   6
HELIX  304 304 PRO K  510  VAL K  513  1                                   4
HELIX  305 305 ASP K  526  ASP K  529  1                                   4
HELIX  306 306 ALA K  540  LEU K  549  1                                  10
HELIX  307 307 VAL K  588  VAL K  591  1                                   4
HELIX  308 308 HIS K  623  ARG K  634  1                                  12
HELIX  309 309 ASP K  636  ASN K  638  1                                   3
HELIX  310 310 THR K  684  GLU K  686  1                                   3
HELIX  311 311 PRO K  705  ASP K  708  1                                   4
HELIX  312 312 ASN K  714  THR K  716  1                                   3
HELIX  313 313 LYS K  762  TYR K  773  1                                  12
HELIX  314 314 SER K  785  LYS K  787  1                                   3
HELIX  315 315 PHE K  793  ASN K  796  1                                   4
HELIX  316 316 ILE K  818  HIS K  820  1                                   3
HELIX  317 317 LEU K  887  GLN K  889  1                                   3
HELIX  318 318 LEU K  891  ASN K  895  1                                   5
HELIX  319 319 PRO L    7  MET L   12  1                                   6
HELIX  320 320 ALA L   19  TYR L   22  1                                   4
HELIX  321 321 PRO L   25  ALA L   33  1                                   9
HELIX  322 322 ASN L   41  LYS L   43  1                                   3
HELIX  323 323 MET L   95  SER L   97  1                                   3
HELIX  324 324 ARG L  311  GLY L  315  1                                   5
HELIX  325 325 ASP L  330  PHE L  332  1                                   3
HELIX  326 326 THR L  341  ASN L  343  1                                   3
HELIX  327 327 THR L  365  ILE L  376  1                                  12
HELIX  328 328 SER L  384  TRP L  386  1                                   3
HELIX  329 329 PRO L  395  ARG L  398  1                                   4
HELIX  330 330 LEU L  463  TYR L  479  1                                  17
HELIX  331 331 ASP L  482  LEU L  484  1                                   3
HELIX  332 332 TYR L  500  LYS L  505  1                                   6
HELIX  333 333 PRO L  510  VAL L  513  1                                   4
HELIX  334 334 ASP L  526  ASP L  529  1                                   4
HELIX  335 335 ALA L  540  LEU L  549  1                                  10
HELIX  336 336 VAL L  588  VAL L  591  1                                   4
HELIX  337 337 HIS L  623  ARG L  634  1                                  12
HELIX  338 338 ASP L  636  ASN L  638  1                                   3
HELIX  339 339 THR L  684  GLU L  686  1                                   3
HELIX  340 340 PRO L  705  ASP L  708  1                                   4
HELIX  341 341 ASN L  714  THR L  716  1                                   3
HELIX  342 342 LYS L  762  TYR L  773  1                                  12
HELIX  343 343 SER L  785  LYS L  787  1                                   3
HELIX  344 344 PHE L  793  ASN L  796  1                                   4
HELIX  345 345 ILE L  818  HIS L  820  1                                   3
HELIX  346 346 LEU L  887  GLN L  889  1                                   3
HELIX  347 347 LEU L  891  ASN L  895  1                                   5
HELIX  348 348 GLU M  177  ASN M  199  1                                  23
HELIX  349 349 LEU M  255  LEU M  259  1                                   5
HELIX  350 350 VAL M  289  SER M  295  1                                   7
HELIX  351 351 TYR M  407  TYR M  410  1                                   4
HELIX  352 352 ILE M  419  SER M  421  1                                   3
HELIX  353 353 GLN M  484  THR M  490  1                                   7
HELIX  354 354 VAL N   10  SER N   16  1                                   7
HELIX  355 355 GLN N   29  ASP N   32  1                                   4
HELIX  356 356 SER N   55  VAL N   61  1                                   7
HELIX  357 357 PRO N   68  HIS N   70  1                                   3
HELIX  358 358 LYS N   72  LEU N   80  1                                   9
HELIX  359 359 GLU N   90  GLY N   92  1                                   3
HELIX  360 360 TYR N   95  ARG N  101  1                                   7
HELIX  361 361 GLY N  108  ASP N  115  1                                   8
HELIX  362 362 GLY N  119  ARG N  122  1                                   4
HELIX  363 363 ALA N  124  GLN N  134  1                                  11
HELIX  364 364 GLY N  138  THR N  149  1                                  12
HELIX  365 365 GLU N  159  GLU N  174  1                                  16
HELIX  366 366 LEU N  201  PHE N  205  1                                   5
HELIX  367 367 PRO N  230  LEU N  236  1                                   7
HELIX  368 368 TYR N  253  ILE N  278  1                                  26
HELIX  369 369 ASP N  289  ASN N  298  1                                  10
HELIX  370 370 PRO O   38  GLU O   57  1                                  20
HELIX  371 371 VAL O   99  THR O  102  1                                   4
HELIX  372 372 LEU O  186  GLU O  190  1                                   5
HELIX  373 373 PRO P   38  GLU P   57  1                                  20
HELIX  374 374 VAL P   99  THR P  102  1                                   4
HELIX  375 375 LEU P  186  GLU P  190  1                                   5
HELIX  376 376 THR Q   45  LEU Q   47  1                                   3
HELIX  377 377 ALA Q   67  ALA Q   70  1                                   4
HELIX  378 378 ALA Q   89  LEU Q  122  1                                  34
HELIX  379 379 LEU Q  124  GLN Q  127  1                                   4
HELIX  380 380 THR R   45  LEU R   47  1                                   3
HELIX  381 381 ASP R   98  ALA R  102  1                                   5
HELIX  382 382 ALA R  105  LEU R  131  1                                  27
HELIX  383 383 THR S   45  LEU S   47  1                                   3
HELIX  384 384 SER S   94  GLN S  119  1                                  26
HELIX  385 385 ASP S  123  GLN S  126  1                                   4
HELIX  386 386 THR T   45  THR T   48  1                                   4
HELIX  387 387 LYS T   99  GLN T  127  1                                  29
SHEET    1   1 1 THR A  64  ILE A  68  0
SHEET    1   2 2 ASP A  71  ASP A  74  0
SHEET    1   3 3 SER A  78  VAL A  87  0
SHEET    1   4 4 THR A  98  ASP A 107  0
SHEET    1   5 5 CYS A 132  TRP A 134  0
SHEET    1   6 6 HIS A 166  PHE A 168  0
SHEET    1   7 7 ALA A 218  LEU A 223  0
SHEET    1   8 8 GLU A 262  PHE A 266  0
SHEET    1   9 9 VAL A 283  GLU A 288  0
SHEET    1  1010 THR A 297  TYR A 301  0
SHEET    1  1111 GLN A 317  PRO A 320  0
SHEET    1  1212 ILE A 326  PHE A 328  0
SHEET    1  1313 VAL A 346  GLY A 349  0
SHEET    1  1414 TYR A 412  PHE A 414  0
SHEET    1  1515 GLU A 423  LEU A 425  0
SHEET    1  1616 VAL A 428  PRO A 430  0
SHEET    1  1717 TRP A 438  LYS A 440  0
SHEET    1  1818 ASN A 449  ILE A 451  0
SHEET    1  1919 ALA A 458  GLU A 460  0
SHEET    1  2020 TYR A 554  VAL A 561  0
SHEET    1  2121 GLY A 576  ARG A 585  0
SHEET    1  2222 LEU A 592  SER A 594  0
SHEET    1  2323 SER A 606  THR A 617  0
SHEET    1  2424 GLN A 640  ASN A 643  0
SHEET    1  2525 ALA A 648  ILE A 655  0
SHEET    1  2626 ASN A 661  ILE A 666  0
SHEET    1  2727 GLY A 676  LYS A 683  0
SHEET    1  2828 PHE A 717  PHE A 724  0
SHEET    1  2929 VAL A 728  TRP A 730  0
SHEET    1  3030 PHE A 797  VAL A 805  0
SHEET    1  3131 SER A 857  CYS A 865  0
SHEET    1  3232 TRP A 870  PRO A 873  0
SHEET    1  3333 LEU A 900  VAL A 906  0
SHEET    1  3434 THR A 913  GLU A 920  0
SHEET    1  3535 PHE A 922  HIS A 928  0
SHEET    1  3636 GLU A 936  THR A 942  0
SHEET    1  3737 THR B  64  ILE B  68  0
SHEET    1  3838 ASP B  71  ASP B  74  0
SHEET    1  3939 SER B  78  VAL B  87  0
SHEET    1  4040 THR B  98  ASP B 107  0
SHEET    1  4141 CYS B 132  TRP B 134  0
SHEET    1  4242 HIS B 166  PHE B 168  0
SHEET    1  4343 ALA B 218  LEU B 223  0
SHEET    1  4444 GLU B 262  PHE B 266  0
SHEET    1  4545 VAL B 283  GLU B 288  0
SHEET    1  4646 THR B 297  TYR B 301  0
SHEET    1  4747 GLN B 317  PRO B 320  0
SHEET    1  4848 ILE B 326  PHE B 328  0
SHEET    1  4949 VAL B 346  GLY B 349  0
SHEET    1  5050 TYR B 412  PHE B 414  0
SHEET    1  5151 GLU B 423  LEU B 425  0
SHEET    1  5252 VAL B 428  PRO B 430  0
SHEET    1  5353 TRP B 438  LYS B 440  0
SHEET    1  5454 ASN B 449  ILE B 451  0
SHEET    1  5555 ALA B 458  GLU B 460  0
SHEET    1  5656 TYR B 554  VAL B 561  0
SHEET    1  5757 GLY B 576  ARG B 585  0
SHEET    1  5858 LEU B 592  SER B 594  0
SHEET    1  5959 SER B 606  THR B 617  0
SHEET    1  6060 GLN B 640  ASN B 643  0
SHEET    1  6161 ALA B 648  ILE B 655  0
SHEET    1  6262 ASN B 661  ILE B 666  0
SHEET    1  6363 GLY B 676  LYS B 683  0
SHEET    1  6464 PHE B 717  PHE B 724  0
SHEET    1  6565 VAL B 728  TRP B 730  0
SHEET    1  6666 PHE B 797  VAL B 805  0
SHEET    1  6767 SER B 857  CYS B 865  0
SHEET    1  6868 TRP B 870  PRO B 873  0
SHEET    1  6969 LEU B 900  VAL B 906  0
SHEET    1  7070 THR B 913  GLU B 920  0
SHEET    1  7171 PHE B 922  HIS B 928  0
SHEET    1  7272 GLU B 936  THR B 942  0
SHEET    1  7373 THR C  64  ILE C  68  0
SHEET    1  7474 ASP C  71  ASP C  74  0
SHEET    1  7575 SER C  78  VAL C  87  0
SHEET    1  7676 THR C  98  ASP C 107  0
SHEET    1  7777 CYS C 132  TRP C 134  0
SHEET    1  7878 HIS C 166  PHE C 168  0
SHEET    1  7979 ALA C 218  LEU C 223  0
SHEET    1  8080 GLU C 262  PHE C 266  0
SHEET    1  8181 VAL C 283  GLU C 288  0
SHEET    1  8282 THR C 297  TYR C 301  0
SHEET    1  8383 GLN C 317  PRO C 320  0
SHEET    1  8484 ILE C 326  PHE C 328  0
SHEET    1  8585 VAL C 346  GLY C 349  0
SHEET    1  8686 TYR C 412  PHE C 414  0
SHEET    1  8787 GLU C 423  LEU C 425  0
SHEET    1  8888 VAL C 428  PRO C 430  0
SHEET    1  8989 TRP C 438  LYS C 440  0
SHEET    1  9090 ASN C 449  ILE C 451  0
SHEET    1  9191 ALA C 458  GLU C 460  0
SHEET    1  9292 TYR C 554  VAL C 561  0
SHEET    1  9393 GLY C 576  ARG C 585  0
SHEET    1  9494 LEU C 592  SER C 594  0
SHEET    1  9595 SER C 606  THR C 617  0
SHEET    1  9696 GLN C 640  ASN C 643  0
SHEET    1  9797 ALA C 648  ILE C 655  0
SHEET    1  9898 ASN C 661  ILE C 666  0
SHEET    1  9999 GLY C 676  LYS C 683  0
SHEET    1 10010 PHE C 717  PHE C 724  0
SHEET    1 10110 VAL C 728  TRP C 730  0
SHEET    1 10210 PHE C 797  VAL C 805  0
SHEET    1 10310 SER C 857  CYS C 865  0
SHEET    1 10410 TRP C 870  PRO C 873  0
SHEET    1 10510 LEU C 900  VAL C 906  0
SHEET    1 10610 THR C 913  GLU C 920  0
SHEET    1 10710 PHE C 922  HIS C 928  0
SHEET    1 10810 GLU C 936  THR C 942  0
SHEET    1 10910 THR D  64  ILE D  68  0
SHEET    1 11011 ASP D  71  ASP D  74  0
SHEET    1 11111 SER D  78  VAL D  87  0
SHEET    1 11211 THR D  98  ASP D 107  0
SHEET    1 11311 CYS D 132  TRP D 134  0
SHEET    1 11411 HIS D 166  PHE D 168  0
SHEET    1 11511 ALA D 218  LEU D 223  0
SHEET    1 11611 GLU D 262  PHE D 266  0
SHEET    1 11711 VAL D 283  GLU D 288  0
SHEET    1 11811 THR D 297  TYR D 301  0
SHEET    1 11911 GLN D 317  PRO D 320  0
SHEET    1 12012 ILE D 326  PHE D 328  0
SHEET    1 12112 VAL D 346  GLY D 349  0
SHEET    1 12212 TYR D 412  PHE D 414  0
SHEET    1 12312 GLU D 423  LEU D 425  0
SHEET    1 12412 VAL D 428  PRO D 430  0
SHEET    1 12512 TRP D 438  LYS D 440  0
SHEET    1 12612 ASN D 449  ILE D 451  0
SHEET    1 12712 ALA D 458  GLU D 460  0
SHEET    1 12812 TYR D 554  VAL D 561  0
SHEET    1 12912 GLY D 576  ARG D 585  0
SHEET    1 13013 LEU D 592  SER D 594  0
SHEET    1 13113 SER D 606  THR D 617  0
SHEET    1 13213 GLN D 640  ASN D 643  0
SHEET    1 13313 ALA D 648  ILE D 655  0
SHEET    1 13413 ASN D 661  ILE D 666  0
SHEET    1 13513 GLY D 676  LYS D 683  0
SHEET    1 13613 PHE D 717  PHE D 724  0
SHEET    1 13713 VAL D 728  TRP D 730  0
SHEET    1 13813 PHE D 797  VAL D 805  0
SHEET    1 13913 SER D 857  CYS D 865  0
SHEET    1 14014 TRP D 870  PRO D 873  0
SHEET    1 14114 LEU D 900  VAL D 906  0
SHEET    1 14214 THR D 913  GLU D 920  0
SHEET    1 14314 PHE D 922  HIS D 928  0
SHEET    1 14414 GLU D 936  THR D 942  0
SHEET    1 14514 THR E  64  ILE E  68  0
SHEET    1 14614 ASP E  71  ASP E  74  0
SHEET    1 14714 SER E  78  VAL E  87  0
SHEET    1 14814 THR E  98  ASP E 107  0
SHEET    1 14914 CYS E 132  TRP E 134  0
SHEET    1 15015 HIS E 166  PHE E 168  0
SHEET    1 15115 ALA E 218  LEU E 223  0
SHEET    1 15215 GLU E 262  PHE E 266  0
SHEET    1 15315 VAL E 283  GLU E 288  0
SHEET    1 15415 THR E 297  TYR E 301  0
SHEET    1 15515 GLN E 317  PRO E 320  0
SHEET    1 15615 ILE E 326  PHE E 328  0
SHEET    1 15715 VAL E 346  GLY E 349  0
SHEET    1 15815 TYR E 412  PHE E 414  0
SHEET    1 15915 GLU E 423  LEU E 425  0
SHEET    1 16016 VAL E 428  PRO E 430  0
SHEET    1 16116 TRP E 438  LYS E 440  0
SHEET    1 16216 ASN E 449  ILE E 451  0
SHEET    1 16316 ALA E 458  GLU E 460  0
SHEET    1 16416 TYR E 554  VAL E 561  0
SHEET    1 16516 GLY E 576  ARG E 585  0
SHEET    1 16616 LEU E 592  SER E 594  0
SHEET    1 16716 SER E 606  THR E 617  0
SHEET    1 16816 GLN E 640  ASN E 643  0
SHEET    1 16916 ALA E 648  ILE E 655  0
SHEET    1 17017 ASN E 661  ILE E 666  0
SHEET    1 17117 GLY E 676  LYS E 683  0
SHEET    1 17217 PHE E 717  PHE E 724  0
SHEET    1 17317 VAL E 728  TRP E 730  0
SHEET    1 17417 PHE E 797  VAL E 805  0
SHEET    1 17517 SER E 857  CYS E 865  0
SHEET    1 17617 TRP E 870  PRO E 873  0
SHEET    1 17717 LEU E 900  VAL E 906  0
SHEET    1 17817 THR E 913  GLU E 920  0
SHEET    1 17917 PHE E 922  HIS E 928  0
SHEET    1 18018 GLU E 936  THR E 942  0
SHEET    1 18118 THR F  64  ILE F  68  0
SHEET    1 18218 ASP F  71  ASP F  74  0
SHEET    1 18318 SER F  78  VAL F  87  0
SHEET    1 18418 THR F  98  ASP F 107  0
SHEET    1 18518 CYS F 132  TRP F 134  0
SHEET    1 18618 HIS F 166  PHE F 168  0
SHEET    1 18718 ALA F 218  LEU F 223  0
SHEET    1 18818 GLU F 262  PHE F 266  0
SHEET    1 18918 VAL F 283  GLU F 288  0
SHEET    1 19019 THR F 297  TYR F 301  0
SHEET    1 19119 GLN F 317  PRO F 320  0
SHEET    1 19219 ILE F 326  PHE F 328  0
SHEET    1 19319 VAL F 346  GLY F 349  0
SHEET    1 19419 TYR F 412  PHE F 414  0
SHEET    1 19519 GLU F 423  LEU F 425  0
SHEET    1 19619 VAL F 428  PRO F 430  0
SHEET    1 19719 TRP F 438  LYS F 440  0
SHEET    1 19819 ASN F 449  ILE F 451  0
SHEET    1 19919 ALA F 458  GLU F 460  0
SHEET    1 20020 TYR F 554  VAL F 561  0
SHEET    1 20120 GLY F 576  ARG F 585  0
SHEET    1 20220 LEU F 592  SER F 594  0
SHEET    1 20320 SER F 606  THR F 617  0
SHEET    1 20420 GLN F 640  ASN F 643  0
SHEET    1 20520 ALA F 648  ILE F 655  0
SHEET    1 20620 ASN F 661  ILE F 666  0
SHEET    1 20720 GLY F 676  LYS F 683  0
SHEET    1 20820 PHE F 717  PHE F 724  0
SHEET    1 20920 VAL F 728  TRP F 730  0
SHEET    1 21021 PHE F 797  VAL F 805  0
SHEET    1 21121 SER F 857  CYS F 865  0
SHEET    1 21221 TRP F 870  PRO F 873  0
SHEET    1 21321 LEU F 900  VAL F 906  0
SHEET    1 21421 THR F 913  GLU F 920  0
SHEET    1 21521 PHE F 922  HIS F 928  0
SHEET    1 21621 GLU F 936  THR F 942  0
SHEET    1 21721 THR G  64  ILE G  68  0
SHEET    1 21821 ASP G  71  ASP G  74  0
SHEET    1 21921 SER G  78  VAL G  87  0
SHEET    1 22022 THR G  98  ASP G 107  0
SHEET    1 22122 CYS G 132  TRP G 134  0
SHEET    1 22222 HIS G 166  PHE G 168  0
SHEET    1 22322 ALA G 218  LEU G 223  0
SHEET    1 22422 GLU G 262  PHE G 266  0
SHEET    1 22522 VAL G 283  GLU G 288  0
SHEET    1 22622 THR G 297  TYR G 301  0
SHEET    1 22722 GLN G 317  PRO G 320  0
SHEET    1 22822 ILE G 326  PHE G 328  0
SHEET    1 22922 VAL G 346  GLY G 349  0
SHEET    1 23023 TYR G 412  PHE G 414  0
SHEET    1 23123 GLU G 423  LEU G 425  0
SHEET    1 23223 VAL G 428  PRO G 430  0
SHEET    1 23323 TRP G 438  LYS G 440  0
SHEET    1 23423 ASN G 449  ILE G 451  0
SHEET    1 23523 ALA G 458  GLU G 460  0
SHEET    1 23623 TYR G 554  VAL G 561  0
SHEET    1 23723 GLY G 576  ARG G 585  0
SHEET    1 23823 LEU G 592  SER G 594  0
SHEET    1 23923 SER G 606  THR G 617  0
SHEET    1 24024 GLN G 640  ASN G 643  0
SHEET    1 24124 ALA G 648  ILE G 655  0
SHEET    1 24224 ASN G 661  ILE G 666  0
SHEET    1 24324 GLY G 676  LYS G 683  0
SHEET    1 24424 PHE G 717  PHE G 724  0
SHEET    1 24524 VAL G 728  TRP G 730  0
SHEET    1 24624 PHE G 797  VAL G 805  0
SHEET    1 24724 SER G 857  CYS G 865  0
SHEET    1 24824 TRP G 870  PRO G 873  0
SHEET    1 24924 LEU G 900  VAL G 906  0
SHEET    1 25025 THR G 913  GLU G 920  0
SHEET    1 25125 PHE G 922  HIS G 928  0
SHEET    1 25225 GLU G 936  THR G 942  0
SHEET    1 25325 THR H  64  ILE H  68  0
SHEET    1 25425 ASP H  71  ASP H  74  0
SHEET    1 25525 SER H  78  VAL H  87  0
SHEET    1 25625 THR H  98  ASP H 107  0
SHEET    1 25725 CYS H 132  TRP H 134  0
SHEET    1 25825 HIS H 166  PHE H 168  0
SHEET    1 25925 ALA H 218  LEU H 223  0
SHEET    1 26026 GLU H 262  PHE H 266  0
SHEET    1 26126 VAL H 283  GLU H 288  0
SHEET    1 26226 THR H 297  TYR H 301  0
SHEET    1 26326 GLN H 317  PRO H 320  0
SHEET    1 26426 ILE H 326  PHE H 328  0
SHEET    1 26526 VAL H 346  GLY H 349  0
SHEET    1 26626 TYR H 412  PHE H 414  0
SHEET    1 26726 GLU H 423  LEU H 425  0
SHEET    1 26826 VAL H 428  PRO H 430  0
SHEET    1 26926 TRP H 438  LYS H 440  0
SHEET    1 27027 ASN H 449  ILE H 451  0
SHEET    1 27127 ALA H 458  GLU H 460  0
SHEET    1 27227 TYR H 554  VAL H 561  0
SHEET    1 27327 GLY H 576  ARG H 585  0
SHEET    1 27427 LEU H 592  SER H 594  0
SHEET    1 27527 SER H 606  THR H 617  0
SHEET    1 27627 GLN H 640  ASN H 643  0
SHEET    1 27727 ALA H 648  ILE H 655  0
SHEET    1 27827 ASN H 661  ILE H 666  0
SHEET    1 27927 GLY H 676  LYS H 683  0
SHEET    1 28028 PHE H 717  PHE H 724  0
SHEET    1 28128 VAL H 728  TRP H 730  0
SHEET    1 28228 PHE H 797  VAL H 805  0
SHEET    1 28328 SER H 857  CYS H 865  0
SHEET    1 28428 TRP H 870  PRO H 873  0
SHEET    1 28528 LEU H 900  VAL H 906  0
SHEET    1 28628 THR H 913  GLU H 920  0
SHEET    1 28728 PHE H 922  HIS H 928  0
SHEET    1 28828 GLU H 936  THR H 942  0
SHEET    1 28928 THR I  64  ILE I  68  0
SHEET    1 29029 ASP I  71  ASP I  74  0
SHEET    1 29129 SER I  78  VAL I  87  0
SHEET    1 29229 THR I  98  ASP I 107  0
SHEET    1 29329 CYS I 132  TRP I 134  0
SHEET    1 29429 HIS I 166  PHE I 168  0
SHEET    1 29529 ALA I 218  LEU I 223  0
SHEET    1 29629 GLU I 262  PHE I 266  0
SHEET    1 29729 VAL I 283  GLU I 288  0
SHEET    1 29829 THR I 297  TYR I 301  0
SHEET    1 29929 GLN I 317  PRO I 320  0
SHEET    1 30030 ILE I 326  PHE I 328  0
SHEET    1 30130 VAL I 346  GLY I 349  0
SHEET    1 30230 TYR I 412  PHE I 414  0
SHEET    1 30330 GLU I 423  LEU I 425  0
SHEET    1 30430 VAL I 428  PRO I 430  0
SHEET    1 30530 TRP I 438  LYS I 440  0
SHEET    1 30630 ASN I 449  ILE I 451  0
SHEET    1 30730 ALA I 458  GLU I 460  0
SHEET    1 30830 TYR I 554  VAL I 561  0
SHEET    1 30930 GLY I 576  ARG I 585  0
SHEET    1 31031 LEU I 592  SER I 594  0
SHEET    1 31131 SER I 606  THR I 617  0
SHEET    1 31231 GLN I 640  ASN I 643  0
SHEET    1 31331 ALA I 648  ILE I 655  0
SHEET    1 31431 ASN I 661  ILE I 666  0
SHEET    1 31531 GLY I 676  LYS I 683  0
SHEET    1 31631 PHE I 717  PHE I 724  0
SHEET    1 31731 VAL I 728  TRP I 730  0
SHEET    1 31831 PHE I 797  VAL I 805  0
SHEET    1 31931 SER I 857  CYS I 865  0
SHEET    1 32032 TRP I 870  PRO I 873  0
SHEET    1 32132 LEU I 900  VAL I 906  0
SHEET    1 32232 THR I 913  GLU I 920  0
SHEET    1 32332 PHE I 922  HIS I 928  0
SHEET    1 32432 GLU I 936  THR I 942  0
SHEET    1 32532 THR J  64  ILE J  68  0
SHEET    1 32632 ASP J  71  ASP J  74  0
SHEET    1 32732 SER J  78  VAL J  87  0
SHEET    1 32832 THR J  98  ASP J 107  0
SHEET    1 32932 CYS J 132  TRP J 134  0
SHEET    1 33033 HIS J 166  PHE J 168  0
SHEET    1 33133 ALA J 218  LEU J 223  0
SHEET    1 33233 GLU J 262  PHE J 266  0
SHEET    1 33333 VAL J 283  GLU J 288  0
SHEET    1 33433 THR J 297  TYR J 301  0
SHEET    1 33533 GLN J 317  PRO J 320  0
SHEET    1 33633 ILE J 326  PHE J 328  0
SHEET    1 33733 VAL J 346  GLY J 349  0
SHEET    1 33833 TYR J 412  PHE J 414  0
SHEET    1 33933 GLU J 423  LEU J 425  0
SHEET    1 34034 VAL J 428  PRO J 430  0
SHEET    1 34134 TRP J 438  LYS J 440  0
SHEET    1 34234 ASN J 449  ILE J 451  0
SHEET    1 34334 ALA J 458  GLU J 460  0
SHEET    1 34434 TYR J 554  VAL J 561  0
SHEET    1 34534 GLY J 576  ARG J 585  0
SHEET    1 34634 LEU J 592  SER J 594  0
SHEET    1 34734 SER J 606  THR J 617  0
SHEET    1 34834 GLN J 640  ASN J 643  0
SHEET    1 34934 ALA J 648  ILE J 655  0
SHEET    1 35035 ASN J 661  ILE J 666  0
SHEET    1 35135 GLY J 676  LYS J 683  0
SHEET    1 35235 PHE J 717  PHE J 724  0
SHEET    1 35335 VAL J 728  TRP J 730  0
SHEET    1 35435 PHE J 797  VAL J 805  0
SHEET    1 35535 SER J 857  CYS J 865  0
SHEET    1 35635 TRP J 870  PRO J 873  0
SHEET    1 35735 LEU J 900  VAL J 906  0
SHEET    1 35835 THR J 913  GLU J 920  0
SHEET    1 35935 PHE J 922  HIS J 928  0
SHEET    1 36036 GLU J 936  THR J 942  0
SHEET    1 36136 THR K  64  PHE K  67  0
SHEET    1 36236 ASP K  71  ASP K  74  0
SHEET    1 36336 SER K  78  VAL K  87  0
SHEET    1 36436 THR K  98  ASP K 107  0
SHEET    1 36536 CYS K 132  TRP K 134  0
SHEET    1 36636 HIS K 166  PHE K 168  0
SHEET    1 36736 ALA K 218  LEU K 223  0
SHEET    1 36836 GLU K 262  PHE K 266  0
SHEET    1 36936 VAL K 283  GLU K 288  0
SHEET    1 37037 THR K 297  TYR K 301  0
SHEET    1 37137 GLN K 317  PRO K 320  0
SHEET    1 37237 ILE K 326  PHE K 328  0
SHEET    1 37337 VAL K 346  GLY K 349  0
SHEET    1 37437 TYR K 412  PHE K 414  0
SHEET    1 37537 GLU K 423  LEU K 425  0
SHEET    1 37637 VAL K 428  PRO K 430  0
SHEET    1 37737 TRP K 438  LYS K 440  0
SHEET    1 37837 ASN K 449  ILE K 451  0
SHEET    1 37937 ALA K 458  GLU K 460  0
SHEET    1 38038 TYR K 554  VAL K 561  0
SHEET    1 38138 GLY K 576  ARG K 585  0
SHEET    1 38238 LEU K 592  SER K 594  0
SHEET    1 38338 SER K 606  THR K 617  0
SHEET    1 38438 GLN K 640  ASN K 643  0
SHEET    1 38538 ALA K 648  ILE K 655  0
SHEET    1 38638 ASN K 661  ILE K 664  0
SHEET    1 38738 GLY K 676  LYS K 683  0
SHEET    1 38838 PHE K 717  PHE K 724  0
SHEET    1 38938 VAL K 728  TRP K 730  0
SHEET    1 39039 PHE K 797  VAL K 805  0
SHEET    1 39139 SER K 857  CYS K 865  0
SHEET    1 39239 TRP K 870  PRO K 873  0
SHEET    1 39339 ASP K 901  VAL K 906  0
SHEET    1 39439 THR K 913  GLU K 920  0
SHEET    1 39539 PHE K 922  HIS K 928  0
SHEET    1 39639 GLU K 936  THR K 942  0
SHEET    1 39739 THR L  64  ILE L  68  0
SHEET    1 39839 ASP L  71  ASP L  74  0
SHEET    1 39939 SER L  78  VAL L  87  0
SHEET    1 40040 THR L  98  ASP L 107  0
SHEET    1 40140 CYS L 132  TRP L 134  0
SHEET    1 40240 HIS L 166  PHE L 168  0
SHEET    1 40340 ALA L 218  LEU L 223  0
SHEET    1 40440 GLU L 262  PHE L 266  0
SHEET    1 40540 VAL L 283  GLU L 288  0
SHEET    1 40640 THR L 297  TYR L 301  0
SHEET    1 40740 GLN L 317  PRO L 320  0
SHEET    1 40840 ILE L 326  PHE L 328  0
SHEET    1 40940 VAL L 346  GLY L 349  0
SHEET    1 41041 TYR L 412  PHE L 414  0
SHEET    1 41141 GLU L 423  LEU L 425  0
SHEET    1 41241 VAL L 428  PRO L 430  0
SHEET    1 41341 TRP L 438  LYS L 440  0
SHEET    1 41441 ASN L 449  ILE L 451  0
SHEET    1 41541 ALA L 458  GLU L 460  0
SHEET    1 41641 TYR L 554  VAL L 561  0
SHEET    1 41741 GLY L 576  ARG L 585  0
SHEET    1 41841 LEU L 592  SER L 594  0
SHEET    1 41941 SER L 606  THR L 617  0
SHEET    1 42042 GLN L 640  ASN L 643  0
SHEET    1 42142 ALA L 648  ILE L 655  0
SHEET    1 42242 ASN L 661  ILE L 666  0
SHEET    1 42342 GLY L 676  LYS L 683  0
SHEET    1 42442 PHE L 717  PHE L 724  0
SHEET    1 42542 VAL L 728  TRP L 730  0
SHEET    1 42642 PHE L 797  VAL L 805  0
SHEET    1 42742 SER L 857  CYS L 865  0
SHEET    1 42842 TRP L 870  PRO L 873  0
SHEET    1 42942 LEU L 900  VAL L 906  0
SHEET    1 43043 THR L 913  GLU L 920  0
SHEET    1 43143 PHE L 922  HIS L 928  0
SHEET    1 43243 GLU L 936  THR L 942  0
SHEET    1 43343 VAL M  69  LEU M  71  0
SHEET    1 43443 ASN M  90  THR M  94  0
SHEET    1 43543 LYS M 124  THR M 129  0
SHEET    1 43643 LYS M 142  LYS M 144  0
SHEET    1 43743 VAL M 147  SER M 150  0
SHEET    1 43843 LYS M 162  GLU M 164  0
SHEET    1 43943 GLU M 167  THR M 169  0
SHEET    1 44044 ILE M 261  LYS M 263  0
SHEET    1 44144 THR M 423  LEU M 425  0
SHEET    1 44244 GLN M 436  SER M 440  0
SHEET    1 44344 VAL M 462  LEU M 467  0
SHEET    1 44444 VAL M 470  SER M 474  0
SHEET    1 44544 THR M 515  ASN M 519  0
SHEET    1 44644 VAL M 538  THR M 544  0
SHEET    1 44744 VAL M 554  VAL M 561  0
SHEET    1 44844 PHE N 188  GLN N 190  0
SHEET    1 44944 THR N 198  ASN N 200  0
CISPEP   1 GLN A  200    PRO A  201          0        -0.28
CISPEP   2 LYS A  251    GLN A  252          0         0.01
CISPEP   3 LYS A  256    LEU A  257          0         0.04
CISPEP   4 LEU A  257    GLU A  258          0         0.08
CISPEP   5 GLN A  434    GLU A  435          0         0.03
CISPEP   6 GLU A  444    PHE A  445          0        -0.16
CISPEP   7 TRP A  730    PRO A  731          0         0.20
CISPEP   8 PHE A  845    PRO A  846          0        -0.06
CISPEP   9 THR A  942    PRO A  943          0        -0.26
CISPEP  10 GLY A  947    ASN A  948          0         0.14
CISPEP  11 GLN B  200    PRO B  201          0        -0.30
CISPEP  12 LYS B  251    GLN B  252          0        -0.02
CISPEP  13 LYS B  256    LEU B  257          0        -0.02
CISPEP  14 LEU B  257    GLU B  258          0        -0.12
CISPEP  15 GLN B  434    GLU B  435          0         0.00
CISPEP  16 GLU B  444    PHE B  445          0        -0.14
CISPEP  17 TRP B  730    PRO B  731          0         0.22
CISPEP  18 PHE B  845    PRO B  846          0        -0.08
CISPEP  19 THR B  942    PRO B  943          0         0.03
CISPEP  20 SER B  945    ALA B  946          0         0.00
CISPEP  21 GLN C  200    PRO C  201          0        -0.33
CISPEP  22 LYS C  251    GLN C  252          0        -0.06
CISPEP  23 LYS C  256    LEU C  257          0         0.03
CISPEP  24 LEU C  257    GLU C  258          0         0.04
CISPEP  25 GLN C  434    GLU C  435          0        -0.02
CISPEP  26 GLU C  444    PHE C  445          0        -0.04
CISPEP  27 TRP C  730    PRO C  731          0         0.31
CISPEP  28 PHE C  845    PRO C  846          0        -0.10
CISPEP  29 THR C  942    PRO C  943          0        -0.04
CISPEP  30 ASN C  948    ALA C  949          0         0.00
CISPEP  31 GLN D  200    PRO D  201          0        -0.40
CISPEP  32 LYS D  251    GLN D  252          0         0.11
CISPEP  33 LYS D  256    LEU D  257          0         0.08
CISPEP  34 LEU D  257    GLU D  258          0         0.04
CISPEP  35 GLN D  434    GLU D  435          0        -0.03
CISPEP  36 GLU D  444    PHE D  445          0        -0.08
CISPEP  37 TRP D  730    PRO D  731          0         0.21
CISPEP  38 PHE D  845    PRO D  846          0         0.00
CISPEP  39 THR D  942    PRO D  943          0        -0.33
CISPEP  40 ASN D  948    ALA D  949          0         0.06
CISPEP  41 GLN E  200    PRO E  201          0        -0.53
CISPEP  42 LYS E  251    GLN E  252          0         0.06
CISPEP  43 LYS E  256    LEU E  257          0        -0.02
CISPEP  44 LEU E  257    GLU E  258          0        -0.01
CISPEP  45 GLN E  434    GLU E  435          0         0.00
CISPEP  46 GLU E  444    PHE E  445          0        -0.08
CISPEP  47 TRP E  730    PRO E  731          0         0.05
CISPEP  48 PHE E  845    PRO E  846          0        -0.14
CISPEP  49 THR E  942    PRO E  943          0        -0.01
CISPEP  50 ASN E  948    ALA E  949          0        -0.03
CISPEP  51 ALA E  949    THR E  950          0         0.00
CISPEP  52 GLN F  200    PRO F  201          0        -0.42
CISPEP  53 LYS F  251    GLN F  252          0        -0.05
CISPEP  54 LYS F  256    LEU F  257          0        -0.11
CISPEP  55 LEU F  257    GLU F  258          0        -0.14
CISPEP  56 GLN F  434    GLU F  435          0         0.04
CISPEP  57 GLU F  444    PHE F  445          0         0.06
CISPEP  58 TRP F  730    PRO F  731          0         0.29
CISPEP  59 PHE F  845    PRO F  846          0        -0.06
CISPEP  60 THR F  942    PRO F  943          0        -0.30
CISPEP  61 ASN F  948    ALA F  949          0        -0.04
CISPEP  62 GLN G  200    PRO G  201          0        -0.38
CISPEP  63 LYS G  251    GLN G  252          0        -0.10
CISPEP  64 LYS G  256    LEU G  257          0         0.11
CISPEP  65 LEU G  257    GLU G  258          0         0.01
CISPEP  66 GLN G  434    GLU G  435          0        -0.09
CISPEP  67 GLU G  444    PHE G  445          0        -0.24
CISPEP  68 TRP G  730    PRO G  731          0         0.33
CISPEP  69 PHE G  845    PRO G  846          0         0.10
CISPEP  70 THR G  942    PRO G  943          0        -0.39
CISPEP  71 SER H    4    MET H    5          0        -0.01
CISPEP  72 GLN H  200    PRO H  201          0        -0.51
CISPEP  73 LYS H  251    GLN H  252          0         0.09
CISPEP  74 LYS H  256    LEU H  257          0         0.05
CISPEP  75 LEU H  257    GLU H  258          0        -0.07
CISPEP  76 GLN H  434    GLU H  435          0         0.09
CISPEP  77 GLU H  444    PHE H  445          0        -0.16
CISPEP  78 TRP H  730    PRO H  731          0         0.29
CISPEP  79 PHE H  845    PRO H  846          0        -0.18
CISPEP  80 THR H  942    PRO H  943          0        -0.28
CISPEP  81 ASN H  948    ALA H  949          0         0.05
CISPEP  82 GLN I  200    PRO I  201          0        -0.29
CISPEP  83 LYS I  251    GLN I  252          0         0.01
CISPEP  84 LYS I  256    LEU I  257          0        -0.02
CISPEP  85 LEU I  257    GLU I  258          0        -0.06
CISPEP  86 GLN I  434    GLU I  435          0         0.05
CISPEP  87 GLU I  444    PHE I  445          0        -0.22
CISPEP  88 TRP I  730    PRO I  731          0         0.29
CISPEP  89 PHE I  845    PRO I  846          0         0.02
CISPEP  90 THR I  942    PRO I  943          0         0.11
CISPEP  91 ASN I  948    ALA I  949          0         0.09
CISPEP  92 ALA I  949    THR I  950          0        -0.06
CISPEP  93 GLN J  200    PRO J  201          0        -0.49
CISPEP  94 LYS J  251    GLN J  252          0        -0.13
CISPEP  95 LYS J  256    LEU J  257          0         0.21
CISPEP  96 LEU J  257    GLU J  258          0        -0.02
CISPEP  97 GLN J  434    GLU J  435          0         0.01
CISPEP  98 GLU J  444    PHE J  445          0         0.00
CISPEP  99 TRP J  730    PRO J  731          0         0.31
CISPEP 100 PHE J  845    PRO J  846          0        -0.14
CISPEP 101 THR J  942    PRO J  943          0        -0.13
CISPEP 102 GLY J  947    ASN J  948          0        -0.07
CISPEP 103 THR J  950    THR J  951          0         0.00
CISPEP 104 GLN K  200    PRO K  201          0        -0.34
CISPEP 105 LYS K  251    GLN K  252          0        -0.03
CISPEP 106 LYS K  256    LEU K  257          0         0.14
CISPEP 107 LEU K  257    GLU K  258          0        -0.14
CISPEP 108 GLN K  434    GLU K  435          0         0.03
CISPEP 109 GLU K  444    PHE K  445          0        -0.05
CISPEP 110 TRP K  730    PRO K  731          0         0.07
CISPEP 111 PHE K  845    PRO K  846          0        -0.13
CISPEP 112 THR K  942    PRO K  943          0        -0.30
CISPEP 113 SER L    4    MET L    5          0         0.02
CISPEP 114 GLN L  200    PRO L  201          0        -0.36
CISPEP 115 LYS L  251    GLN L  252          0        -0.03
CISPEP 116 LYS L  256    LEU L  257          0         0.11
CISPEP 117 LEU L  257    GLU L  258          0         0.14
CISPEP 118 GLN L  434    GLU L  435          0        -0.01
CISPEP 119 GLU L  444    PHE L  445          0        -0.05
CISPEP 120 TRP L  730    PRO L  731          0         0.13
CISPEP 121 PHE L  845    PRO L  846          0        -0.11
CISPEP 122 THR L  942    PRO L  943          0        -0.20
CISPEP 123 ASN L  948    ALA L  949          0        -0.02
CRYST1    1.000    1.000    1.000  90.00  90.00  90.00 P 1           1
ORIGX1      1.000000  0.000000  0.000000        0.00000
ORIGX2      0.000000  1.000000  0.000000        0.00000
ORIGX3      0.000000  0.000000  1.000000        0.00000
SCALE1      1.000000  0.000000  0.000000        0.00000
SCALE2      0.000000  1.000000  0.000000        0.00000
SCALE3      0.000000  0.000000  1.000000        0.00000
      
PROCHECK
Go to PROCHECK summary
 References