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PDBsum entry 3iti

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Hydrolase PDB id
3iti
Contents
Protein chain
223 a.a.
Ligands
BRV
BEN
Metals
_CL
_CA
Waters ×243

References listed in PDB file
Key reference
Title How to get the magic triangle and the mad triangle into your protein crystal.
Authors T.Beck, C.E.Da cunha, G.M.Sheldrick.
Ref. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2009, 65, 1068-1070.
PubMed id 19851024
Abstract
The magic triangle 5-amino-2,4,6-triiodoisophthalic acid (I3C) and the MAD triangle 5-amino-2,4,6-tribromoisophthalic acid (B3C) are two representatives of a novel class of compounds that combine heavy atoms for experimental phasing with functional groups for protein interactions. These compounds are readily available and provide easy access to experimental phasing. The preparation of stock solutions and the incorporation of the compounds into protein crystals are discussed. As an example of incorporation via cocrystallization, the incorporation of B3C into bovine trypsin, resulting in a single site with high occupancy, is described.
Secondary reference #1
Title The magic triangle goes mad: phasing with a bromine derivative
Authors T.Beck, T.Gruene, G.M.Sheldrick.
Ref. acta crystallogr ,sect d ...
Secondary reference #2
Title 5-Amino-2,4,6-Tribromoisophthalic acid: the mad triangle for experimental phasing.
Authors T.Beck, R.Herbst-Irmer, G.M.Sheldrick.
Ref. Acta Crystallogr C, 2009, 65, o237. [DOI no: 10.1107/S0108270109013195]
PubMed id 19407425
Full text Abstract
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