UniProt functional annotation for Q8GNS3



	UniProt functional annotation for Q8GNS3

UniProt code: Q8GNS3.

Organism: Legionella pneumophila.

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Legionellaceae; Legionella.

Function: Probable transporter of a GTP-driven Fe(2+) uptake system. Seems to be required for optimal intracellular infection of macrophages, to be important for growth and/or survival in iron- restricted amoebae. It also plays a key role in extracellular growth under iron-limited conditions. {ECO:0000269|PubMed:12228295}.

Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:P33650}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33650}.

Similarity: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. {ECO:0000255|PROSITE-ProRule:PRU01048}.

Annotations taken from UniProtKB at the EBI.


Organism:		Legionella pneumophila.
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Legionellaceae; Legionella.



Function:		Probable transporter of a GTP-driven Fe(2+) uptake system. Seems to be required for optimal intracellular infection of macrophages, to be important for growth and/or survival in iron- restricted amoebae. It also plays a key role in extracellular growth under iron-limited conditions. {ECO:0000269\|PubMed:12228295}.


Subcellular location:		Cell inner membrane {ECO:0000250\|UniProtKB:P33650}; Multi-pass membrane protein {ECO:0000250\|UniProtKB:P33650}.
Similarity:		Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. {ECO:0000255\|PROSITE-ProRule:PRU01048}.