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PDBsum entry 3i8f

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Ribosome PDB id
3i8f
Jmol
Contents
Protein chains
272 a.a.
205 a.a.
208 a.a.
181 a.a.
170 a.a.
146 a.a.
138 a.a.
122 a.a.
150 a.a.
141 a.a.
117 a.a.
111 a.a.
137 a.a.
117 a.a.
101 a.a.
113 a.a.
92 a.a.
102 a.a.
187 a.a.
84 a.a.
97 a.a.
69 a.a.
59 a.a.
71 a.a.
59 a.a.
45 a.a.
49 a.a.
64 a.a.
DNA/RNA
HEADER    RIBOSOME                                09-JUL-09   3I8F
TITLE     ELONGATION COMPLEX OF THE 70S RIBOSOME WITH THREE TRNAS AND MRNA.THIS
TITLE    2 ENTRY 3I8F CONTAINS 50S RIBOSOMAL SUBUNIT. THE 30S RIBOSOMAL SUBUNIT
TITLE    3 CAN BE FOUND IN PDB ENTRY 3I8G. MOLECULE B IN THE SAME ASYMMETRIC
TITLE    4 UNIT IS DEPOSITED AS 3I8G (30S) AND 3I8F (50S).
SPLIT      3I8F 3I8G 3I8H 3I8I
COMPND    MOL_ID: 1;
COMPND   2 MOLECULE: 23S RIBOSOMAL RNA;
COMPND   3 CHAIN: A;
COMPND   4 MOL_ID: 2;
COMPND   5 MOLECULE: 5S RIBOSOMAL RNA;
COMPND   6 CHAIN: B;
COMPND   7 MOL_ID: 3;
COMPND   8 MOLECULE: 50S RIBOSOMAL PROTEIN L2;
COMPND   9 CHAIN: D;
COMPND  10 MOL_ID: 4;
COMPND  11 MOLECULE: 50S RIBOSOMAL PROTEIN L3;
COMPND  12 CHAIN: E;
COMPND  13 MOL_ID: 5;
COMPND  14 MOLECULE: 50S RIBOSOMAL PROTEIN L4;
COMPND  15 CHAIN: F;
COMPND  16 MOL_ID: 6;
COMPND  17 MOLECULE: 50S RIBOSOMAL PROTEIN L5;
COMPND  18 CHAIN: G;
COMPND  19 MOL_ID: 7;
COMPND  20 MOLECULE: 50S RIBOSOMAL PROTEIN L6;
COMPND  21 CHAIN: H;
COMPND  22 MOL_ID: 8;
COMPND  23 MOLECULE: 50S RIBOSOMAL PROTEIN L9;
COMPND  24 CHAIN: K;
COMPND  25 MOL_ID: 9;
COMPND  26 MOLECULE: 50S RIBOSOMAL PROTEIN L13;
COMPND  27 CHAIN: M;
COMPND  28 MOL_ID: 10;
COMPND  29 MOLECULE: 50S RIBOSOMAL PROTEIN L14;
COMPND  30 CHAIN: N;
COMPND  31 MOL_ID: 11;
COMPND  32 MOLECULE: 50S RIBOSOMAL PROTEIN L15;
COMPND  33 CHAIN: O;
COMPND  34 MOL_ID: 12;
COMPND  35 MOLECULE: 50S RIBOSOMAL PROTEIN L16;
COMPND  36 CHAIN: P;
COMPND  37 MOL_ID: 13;
COMPND  38 MOLECULE: 50S RIBOSOMAL PROTEIN L17;
COMPND  39 CHAIN: 0;
COMPND  40 MOL_ID: 14;
COMPND  41 MOLECULE: 50S RIBOSOMAL PROTEIN L18;
COMPND  42 CHAIN: Q;
COMPND  43 MOL_ID: 15;
COMPND  44 MOLECULE: 50S RIBOSOMAL PROTEIN L19;
COMPND  45 CHAIN: R;
COMPND  46 MOL_ID: 16;
COMPND  47 MOLECULE: 50S RIBOSOMAL PROTEIN L20;
COMPND  48 CHAIN: 1;
COMPND  49 MOL_ID: 17;
COMPND  50 MOLECULE: 50S RIBOSOMAL PROTEIN L21;
COMPND  51 CHAIN: 2;
COMPND  52 MOL_ID: 18;
COMPND  53 MOLECULE: 50S RIBOSOMAL PROTEIN L22;
COMPND  54 CHAIN: S;
COMPND  55 MOL_ID: 19;
COMPND  56 MOLECULE: 50S RIBOSOMAL PROTEIN L23;
COMPND  57 CHAIN: T;
COMPND  58 MOL_ID: 20;
COMPND  59 MOLECULE: 50S RIBOSOMAL PROTEIN L24;
COMPND  60 CHAIN: U;
COMPND  61 MOL_ID: 21;
COMPND  62 MOLECULE: 50S RIBOSOMAL PROTEIN L25;
COMPND  63 CHAIN: V;
COMPND  64 MOL_ID: 22;
COMPND  65 MOLECULE: 50S RIBOSOMAL PROTEIN L27;
COMPND  66 CHAIN: 3;
COMPND  67 MOL_ID: 23;
COMPND  68 MOLECULE: 50S RIBOSOMAL PROTEIN L28;
COMPND  69 CHAIN: Z;
COMPND  70 MOL_ID: 24;
COMPND  71 MOLECULE: 50S RIBOSOMAL PROTEIN L29;
COMPND  72 CHAIN: W;
COMPND  73 MOL_ID: 25;
COMPND  74 MOLECULE: 50S RIBOSOMAL PROTEIN L30;
COMPND  75 CHAIN: X;
COMPND  76 MOL_ID: 26;
COMPND  77 MOLECULE: 50S RIBOSOMAL PROTEIN L31;
COMPND  78 CHAIN: 4;
COMPND  79 MOL_ID: 27;
COMPND  80 MOLECULE: 50S RIBOSOMAL PROTEIN L32;
COMPND  81 CHAIN: 5;
COMPND  82 MOL_ID: 28;
COMPND  83 MOLECULE: 50S RIBOSOMAL PROTEIN L33;
COMPND  84 CHAIN: 6;
COMPND  85 MOL_ID: 29;
COMPND  86 MOLECULE: 50S RIBOSOMAL PROTEIN L34;
COMPND  87 CHAIN: 7;
COMPND  88 MOL_ID: 30;
COMPND  89 MOLECULE: 50S RIBOSOMAL PROTEIN L35;
COMPND  90 CHAIN: 8
SOURCE    MOL_ID: 1;
SOURCE   2 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE   3 ORGANISM_TAXID: 300852;
SOURCE   4 STRAIN: HB8;
SOURCE   5 MOL_ID: 2;
SOURCE   6 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE   7 ORGANISM_TAXID: 300852;
SOURCE   8 STRAIN: HB8;
SOURCE   9 MOL_ID: 3;
SOURCE  10 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  11 ORGANISM_TAXID: 300852;
SOURCE  12 STRAIN: HB8;
SOURCE  13 MOL_ID: 4;
SOURCE  14 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  15 ORGANISM_TAXID: 300852;
SOURCE  16 STRAIN: HB8;
SOURCE  17 MOL_ID: 5;
SOURCE  18 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  19 ORGANISM_TAXID: 300852;
SOURCE  20 STRAIN: HB8;
SOURCE  21 MOL_ID: 6;
SOURCE  22 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  23 ORGANISM_TAXID: 300852;
SOURCE  24 STRAIN: HB8;
SOURCE  25 MOL_ID: 7;
SOURCE  26 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  27 ORGANISM_TAXID: 300852;
SOURCE  28 STRAIN: HB8;
SOURCE  29 MOL_ID: 8;
SOURCE  30 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  31 ORGANISM_TAXID: 300852;
SOURCE  32 STRAIN: HB8;
SOURCE  33 MOL_ID: 9;
SOURCE  34 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  35 ORGANISM_TAXID: 300852;
SOURCE  36 STRAIN: HB8;
SOURCE  37 MOL_ID: 10;
SOURCE  38 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  39 ORGANISM_TAXID: 300852;
SOURCE  40 STRAIN: HB8;
SOURCE  41 MOL_ID: 11;
SOURCE  42 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  43 ORGANISM_TAXID: 300852;
SOURCE  44 STRAIN: HB8;
SOURCE  45 MOL_ID: 12;
SOURCE  46 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  47 ORGANISM_TAXID: 300852;
SOURCE  48 STRAIN: HB8;
SOURCE  49 MOL_ID: 13;
SOURCE  50 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  51 ORGANISM_TAXID: 300852;
SOURCE  52 STRAIN: HB8;
SOURCE  53 MOL_ID: 14;
SOURCE  54 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  55 ORGANISM_TAXID: 300852;
SOURCE  56 STRAIN: HB8;
SOURCE  57 MOL_ID: 15;
SOURCE  58 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  59 ORGANISM_TAXID: 300852;
SOURCE  60 STRAIN: HB8;
SOURCE  61 MOL_ID: 16;
SOURCE  62 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  63 ORGANISM_TAXID: 300852;
SOURCE  64 STRAIN: HB8;
SOURCE  65 MOL_ID: 17;
SOURCE  66 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  67 ORGANISM_TAXID: 300852;
SOURCE  68 STRAIN: HB8;
SOURCE  69 MOL_ID: 18;
SOURCE  70 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  71 ORGANISM_TAXID: 300852;
SOURCE  72 STRAIN: HB8;
SOURCE  73 MOL_ID: 19;
SOURCE  74 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  75 ORGANISM_TAXID: 300852;
SOURCE  76 STRAIN: HB8;
SOURCE  77 MOL_ID: 20;
SOURCE  78 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  79 ORGANISM_TAXID: 300852;
SOURCE  80 STRAIN: HB8;
SOURCE  81 MOL_ID: 21;
SOURCE  82 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  83 ORGANISM_TAXID: 300852;
SOURCE  84 STRAIN: HB8;
SOURCE  85 MOL_ID: 22;
SOURCE  86 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  87 ORGANISM_TAXID: 300852;
SOURCE  88 STRAIN: HB8;
SOURCE  89 MOL_ID: 23;
SOURCE  90 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  91 ORGANISM_TAXID: 300852;
SOURCE  92 STRAIN: HB8;
SOURCE  93 MOL_ID: 24;
SOURCE  94 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  95 ORGANISM_TAXID: 300852;
SOURCE  96 STRAIN: HB8;
SOURCE  97 MOL_ID: 25;
SOURCE  98 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE  99 ORGANISM_TAXID: 300852;
SOURCE 100 STRAIN: HB8;
SOURCE 101 MOL_ID: 26;
SOURCE 102 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE 103 ORGANISM_TAXID: 300852;
SOURCE 104 STRAIN: HB8;
SOURCE 105 MOL_ID: 27;
SOURCE 106 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE 107 ORGANISM_TAXID: 300852;
SOURCE 108 STRAIN: HB8;
SOURCE 109 MOL_ID: 28;
SOURCE 110 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE 111 ORGANISM_TAXID: 300852;
SOURCE 112 STRAIN: HB8;
SOURCE 113 MOL_ID: 29;
SOURCE 114 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE 115 ORGANISM_TAXID: 300852;
SOURCE 116 STRAIN: HB8;
SOURCE 117 MOL_ID: 30;
SOURCE 118 ORGANISM_SCIENTIFIC: THERMUS THERMOPHILUS;
SOURCE 119 ORGANISM_TAXID: 300852;
SOURCE 120 STRAIN: HB8
KEYWDS    RIBOSOME, TRNA, MRNA
EXPDTA    X-RAY DIFFRACTION
AUTHOR    L.B.JENNER,G.YUSUPOVA,M.YUSUPOV
REVDAT   2   02-JUN-10 3I8F    1       JRNL
REVDAT   1   21-APR-10 3I8F    0
JRNL        AUTH   L.B.JENNER,N.DEMESHKINA,G.YUSUPOVA,M.YUSUPOV
JRNL        TITL   STRUCTURAL ASPECTS OF MESSENGER RNA READING FRAME
JRNL        TITL 2 MAINTENANCE BY THE RIBOSOME.
JRNL        REF    NAT.STRUCT.MOL.BIOL.          V.  17   555 2010
JRNL        REFN                   ISSN 1545-9993
JRNL        PMID   20400952
JRNL        DOI    10.1038/NSMB.1790
REMARK   2
REMARK   2 RESOLUTION.    3.10 ANGSTROMS.
REMARK   3
REMARK   3 REFINEMENT.
REMARK   3   PROGRAM     : CNS
REMARK   3   AUTHORS     : BRUNGER,ADAMS,CLORE,DELANO,GROS,GROSSE-
REMARK   3               : KUNSTLEVE,JIANG,KUSZEWSKI,NILGES,PANNU,
REMARK   3               : READ,RICE,SIMONSON,WARREN
REMARK   3
REMARK   3  REFINEMENT TARGET : ENGH & HUBER
REMARK   3
REMARK   3  DATA USED IN REFINEMENT.
REMARK   3   RESOLUTION RANGE HIGH (ANGSTROMS) : 3.10
REMARK   3   RESOLUTION RANGE LOW  (ANGSTROMS) : 300.00
REMARK   3   DATA CUTOFF            (SIGMA(F)) : 0.000
REMARK   3   DATA CUTOFF HIGH         (ABS(F)) : NULL
REMARK   3   DATA CUTOFF LOW          (ABS(F)) : NULL
REMARK   3   COMPLETENESS (WORKING+TEST)   (%) : 96.5
REMARK   3   NUMBER OF REFLECTIONS             : 1041126
REMARK   3
REMARK   3  FIT TO DATA USED IN REFINEMENT.
REMARK   3   CROSS-VALIDATION METHOD          : THROUGHOUT
REMARK   3   FREE R VALUE TEST SET SELECTION  : RANDOM
REMARK   3   R VALUE            (WORKING SET) : 0.215
REMARK   3   FREE R VALUE                     : 0.255
REMARK   3   FREE R VALUE TEST SET SIZE   (%) : NULL
REMARK   3   FREE R VALUE TEST SET COUNT      : 31119
REMARK   3   ESTIMATED ERROR OF FREE R VALUE  : NULL
REMARK   3
REMARK   3  FIT IN THE HIGHEST RESOLUTION BIN.
REMARK   3   TOTAL NUMBER OF BINS USED           : NULL
REMARK   3   BIN RESOLUTION RANGE HIGH       (A) : 3.10
REMARK   3   BIN RESOLUTION RANGE LOW        (A) : 3.12
REMARK   3   BIN COMPLETENESS (WORKING+TEST) (%) : NULL
REMARK   3   REFLECTIONS IN BIN    (WORKING SET) : NULL
REMARK   3   BIN R VALUE           (WORKING SET) : 0.3240
REMARK   3   BIN FREE R VALUE                    : 0.3485
REMARK   3   BIN FREE R VALUE TEST SET SIZE  (%) : NULL
REMARK   3   BIN FREE R VALUE TEST SET COUNT     : 595
REMARK   3   ESTIMATED ERROR OF BIN FREE R VALUE : NULL
REMARK   3
REMARK   3  NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT.
REMARK   3   PROTEIN ATOMS            : 27007
REMARK   3   NUCLEIC ACID ATOMS       : 65264
REMARK   3   HETEROGEN ATOMS          : 0
REMARK   3   SOLVENT ATOMS            : 0
REMARK   3
REMARK   3  B VALUES.
REMARK   3   FROM WILSON PLOT           (A**2) : 69.14
REMARK   3   MEAN B VALUE      (OVERALL, A**2) : 79.45
REMARK   3   OVERALL ANISOTROPIC B VALUE.
REMARK   3    B11 (A**2) : NULL
REMARK   3    B22 (A**2) : NULL
REMARK   3    B33 (A**2) : NULL
REMARK   3    B12 (A**2) : NULL
REMARK   3    B13 (A**2) : NULL
REMARK   3    B23 (A**2) : NULL
REMARK   3
REMARK   3  ESTIMATED COORDINATE ERROR.
REMARK   3   ESD FROM LUZZATI PLOT        (A) : NULL
REMARK   3   ESD FROM SIGMAA              (A) : NULL
REMARK   3   LOW RESOLUTION CUTOFF        (A) : NULL
REMARK   3
REMARK   3  CROSS-VALIDATED ESTIMATED COORDINATE ERROR.
REMARK   3   ESD FROM C-V LUZZATI PLOT    (A) : NULL
REMARK   3   ESD FROM C-V SIGMAA          (A) : NULL
REMARK   3
REMARK   3  RMS DEVIATIONS FROM IDEAL VALUES.
REMARK   3   BOND LENGTHS                 (A) : NULL
REMARK   3   BOND ANGLES            (DEGREES) : NULL
REMARK   3   DIHEDRAL ANGLES        (DEGREES) : NULL
REMARK   3   IMPROPER ANGLES        (DEGREES) : NULL
REMARK   3
REMARK   3  ISOTROPIC THERMAL MODEL : NULL
REMARK   3
REMARK   3  ISOTROPIC THERMAL FACTOR RESTRAINTS.    RMS    SIGMA
REMARK   3   MAIN-CHAIN BOND              (A**2) : NULL  ; NULL
REMARK   3   MAIN-CHAIN ANGLE             (A**2) : NULL  ; NULL
REMARK   3   SIDE-CHAIN BOND              (A**2) : NULL  ; NULL
REMARK   3   SIDE-CHAIN ANGLE             (A**2) : NULL  ; NULL
REMARK   3
REMARK   3  BULK SOLVENT MODELING.
REMARK   3   METHOD USED : NULL
REMARK   3   KSOL        : NULL
REMARK   3   BSOL        : NULL
REMARK   3
REMARK   3  NCS MODEL : NULL
REMARK   3
REMARK   3  NCS RESTRAINTS.                         RMS   SIGMA/WEIGHT
REMARK   3   GROUP  1  POSITIONAL            (A) : NULL  ; NULL
REMARK   3   GROUP  1  B-FACTOR           (A**2) : NULL  ; NULL
REMARK   3
REMARK   3  PARAMETER FILE  1  : NULL
REMARK   3  TOPOLOGY FILE  1   : NULL
REMARK   3
REMARK   3  OTHER REFINEMENT REMARKS: NULL
REMARK   4
REMARK   4 3I8F COMPLIES WITH FORMAT V. 3.20, 01-DEC-08
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 28-JUL-09.
REMARK 100 THE RCSB ID CODE IS RCSB054094.
REMARK 200
REMARK 200 EXPERIMENTAL DETAILS
REMARK 200  EXPERIMENT TYPE                : X-RAY DIFFRACTION
REMARK 200  DATE OF DATA COLLECTION        : NULL
REMARK 200  TEMPERATURE           (KELVIN) : 100
REMARK 200  PH                             : 7.5
REMARK 200  NUMBER OF CRYSTALS USED        : 1
REMARK 200
REMARK 200  SYNCHROTRON              (Y/N) : Y
REMARK 200  RADIATION SOURCE               : SLS
REMARK 200  BEAMLINE                       : X06SA
REMARK 200  X-RAY GENERATOR MODEL          : NULL
REMARK 200  MONOCHROMATIC OR LAUE    (M/L) : M
REMARK 200  WAVELENGTH OR RANGE        (A) : 1.000
REMARK 200  MONOCHROMATOR                  : SI 111
REMARK 200  OPTICS                         : NULL
REMARK 200
REMARK 200  DETECTOR TYPE                  : PIXEL
REMARK 200  DETECTOR MANUFACTURER          : PSI PILATUS 6M
REMARK 200  INTENSITY-INTEGRATION SOFTWARE : XDS
REMARK 200  DATA SCALING SOFTWARE          : XSCALE
REMARK 200
REMARK 200  NUMBER OF UNIQUE REFLECTIONS   : 1041156
REMARK 200  RESOLUTION RANGE HIGH      (A) : 3.100
REMARK 200  RESOLUTION RANGE LOW       (A) : 300.000
REMARK 200  REJECTION CRITERIA  (SIGMA(I)) : 0.000
REMARK 200
REMARK 200 OVERALL.
REMARK 200  COMPLETENESS FOR RANGE     (%) : 96.5
REMARK 200  DATA REDUNDANCY                : 9.100
REMARK 200  R MERGE                    (I) : 0.19100
REMARK 200  R SYM                      (I) : 0.26600
REMARK 200   FOR THE DATA SET  : 6.9400
REMARK 200
REMARK 200 IN THE HIGHEST RESOLUTION SHELL.
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 3.10
REMARK 200  HIGHEST RESOLUTION SHELL, RANGE LOW  (A) : 3.20
REMARK 200  COMPLETENESS FOR SHELL     (%) : 88.4
REMARK 200  DATA REDUNDANCY IN SHELL       : 8.86
REMARK 200  R MERGE FOR SHELL          (I) : 0.60000
REMARK 200  R SYM FOR SHELL            (I) : 0.60000
REMARK 200   FOR SHELL         : 1.900
REMARK 200
REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH
REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MOLECULAR REPLACEMENT
REMARK 200 SOFTWARE USED: CNS
REMARK 200 STARTING MODEL: 2J00, 2J01, 2J02, 2J03
REMARK 200
REMARK 200 REMARK: NULL
REMARK 280
REMARK 280 CRYSTAL
REMARK 280 SOLVENT CONTENT, VS   (%): NULL
REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): NULL
REMARK 280
REMARK 280 CRYSTALLIZATION CONDITIONS: 4% PEG20K, 4% PEGMME 550, 100MM TRIS/
REMARK 280  HAC, 200MM KSCN, PH 7.5, VAPOR DIFFUSION, TEMPERATURE 293K
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY
REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 21 21
REMARK 290
REMARK 290      SYMOP   SYMMETRY
REMARK 290     NNNMMM   OPERATOR
REMARK 290       1555   X,Y,Z
REMARK 290       2555   -X+1/2,-Y,Z+1/2
REMARK 290       3555   -X,Y+1/2,-Z+1/2
REMARK 290       4555   X+1/2,-Y+1/2,-Z
REMARK 290
REMARK 290     WHERE NNN -> OPERATOR NUMBER
REMARK 290           MMM -> TRANSLATION VECTOR
REMARK 290
REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS
REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM
REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY
REMARK 290 RELATED MOLECULES.
REMARK 290   SMTRY1   1  1.000000  0.000000  0.000000        0.00000
REMARK 290   SMTRY2   1  0.000000  1.000000  0.000000        0.00000
REMARK 290   SMTRY3   1  0.000000  0.000000  1.000000        0.00000
REMARK 290   SMTRY1   2 -1.000000  0.000000  0.000000      104.73000
REMARK 290   SMTRY2   2  0.000000 -1.000000  0.000000        0.00000
REMARK 290   SMTRY3   2  0.000000  0.000000  1.000000      311.52500
REMARK 290   SMTRY1   3 -1.000000  0.000000  0.000000        0.00000
REMARK 290   SMTRY2   3  0.000000  1.000000  0.000000      223.10000
REMARK 290   SMTRY3   3  0.000000  0.000000 -1.000000      311.52500
REMARK 290   SMTRY1   4  1.000000  0.000000  0.000000      104.73000
REMARK 290   SMTRY2   4  0.000000 -1.000000  0.000000      223.10000
REMARK 290   SMTRY3   4  0.000000  0.000000 -1.000000        0.00000
REMARK 290
REMARK 290 REMARK: NULL
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 300 REMARK: THE BIOLOGICAL MOLECULE IS COMPOSED OF BOTH THE 30S AND 50S
REMARK 300 SUBUNITS OF MOLECULE A AND B
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW.  BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 30-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, D, E, F, G, H, K, M,
REMARK 350                    AND CHAINS: N, O, P, 0, Q, R, 1, 2, S,
REMARK 350                    AND CHAINS: T, U, V, 3, Z, W, X, 4, 5,
REMARK 350                    AND CHAINS: 6, 7, 8
REMARK 350   BIOMT1   1  1.000000  0.000000  0.000000        0.00000
REMARK 350   BIOMT2   1  0.000000  1.000000  0.000000        0.00000
REMARK 350   BIOMT3   1  0.000000  0.000000  1.000000        0.00000
REMARK 400
REMARK 400 COMPOUND
REMARK 400 COMPOUND THE COMPLETE ASYMMETRIC UNIT CONTAINS 30S AND 50S
REMARK 400 RIBOSOMAL SUBUNITS. THIS ENTRY 3I8F CONTAINS 50S RIBOSOMAL SUBUNIT
REMARK 400 OF MOLECULE B. THE 30S RIBOSOMAL SUBUNIT CAN BE FOUND IN PDB ENTRY
REMARK 400 3I8G. MOLECULE A IN THE SAME ASYMMETRIC UNIT IS DEPOSITED AS 3I8H
REMARK 400 (30S) AND 3I8I(50).
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465   M RES C SSSEQI
REMARK 465     MET D     1
REMARK 465     ARG D   274
REMARK 465     LYS D   275
REMARK 465     LYS D   276
REMARK 465     LYS E   206
REMARK 465     GLU F   209
REMARK 465     ALA F   210
REMARK 465     MET G     1
REMARK 465     MET H     1
REMARK 465     LYS H   172
REMARK 465     PRO H   173
REMARK 465     GLY H   174
REMARK 465     LYS H   175
REMARK 465     ALA H   176
REMARK 465     GLY H   177
REMARK 465     ALA H   178
REMARK 465     LYS H   179
REMARK 465     LYS H   180
REMARK 465     GLN K   147
REMARK 465     GLU K   148
REMARK 465     GLU M   139
REMARK 465     VAL M   140
REMARK 465     MET 0     1
REMARK 465     MET Q     1
REMARK 465     ALA R   138
REMARK 465     GLN R   139
REMARK 465     GLU R   140
REMARK 465     PRO R   141
REMARK 465     LYS R   142
REMARK 465     ALA R   143
REMARK 465     SER R   144
REMARK 465     GLN R   145
REMARK 465     GLU R   146
REMARK 465     MET 1     1
REMARK 465     MET T     1
REMARK 465     LYS T     2
REMARK 465     LEU T    95
REMARK 465     ILE T    96
REMARK 465     MET U     1
REMARK 465     GLY U   104
REMARK 465     ALA U   105
REMARK 465     LEU U   106
REMARK 465     ASP U   107
REMARK 465     THR U   108
REMARK 465     GLU U   109
REMARK 465     GLU U   110
REMARK 465     ALA V   188
REMARK 465     ALA V   189
REMARK 465     GLU V   190
REMARK 465     VAL V   191
REMARK 465     ALA V   192
REMARK 465     GLU V   193
REMARK 465     PRO V   194
REMARK 465     GLU V   195
REMARK 465     VAL V   196
REMARK 465     ILE V   197
REMARK 465     LYS V   198
REMARK 465     LYS V   199
REMARK 465     GLY V   200
REMARK 465     LYS V   201
REMARK 465     GLU V   202
REMARK 465     GLU V   203
REMARK 465     GLU V   204
REMARK 465     GLU V   205
REMARK 465     GLU V   206
REMARK 465     MET 3     1
REMARK 465     MET Z     1
REMARK 465     MET W     1
REMARK 465     LYS W     2
REMARK 465     LEU W     3
REMARK 465     MET X     1
REMARK 465     MET 5     1
REMARK 465     MET 6     1
REMARK 465     ALA 6     2
REMARK 465     SER 6     3
REMARK 465     GLU 6     4
REMARK 465     VAL 6     5
REMARK 465     ARG 6     6
REMARK 465     ILE 6     7
REMARK 465     LYS 6     8
REMARK 465     ILE 6    54
REMARK 465     MET 8     1
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500  ATM1  RES C  SSEQI   ATM2  RES C  SSEQI           DISTANCE
REMARK 500   O2'    A A   821     OP2    G A   946              1.19
REMARK 500   O2'    A A  2820     CD2  HIS 0     3              1.33
REMARK 500   O2'    A A  2820     NE2  HIS 0     3              1.54
REMARK 500   O2'    A A  2820     CG   HIS 0     3              1.58
REMARK 500   CG   PRO 6    41     O    LYS 6    45              1.77
REMARK 500   O2'    U A  1341     O2'    U A  1397              1.79
REMARK 500   N2     G A   458     OP2    A A   470              1.82
REMARK 500   O2'    G A   946     C5'    G A   947              1.83
REMARK 500   N6     A A  2820     N    ASN E   192              1.84
REMARK 500   O2'    G A   458     OP2    U A   459              1.85
REMARK 500   O2'    A A  2820     CE1  HIS 0     3              1.86
REMARK 500   O2'    A A  2820     ND1  HIS 0     3              1.86
REMARK 500   CB   PRO V   108     O    VAL V   141              1.87
REMARK 500   N7     G A  2599     O    GLY D   236              1.91
REMARK 500   O2'    A A   752     OP2    C A   753              1.93
REMARK 500   N1     G A   585     OP1    A A  1253              1.94
REMARK 500   CD   PRO 6    41     O    LYS 6    45              1.95
REMARK 500   O2'    A A  1342     OP2    G A  1344              1.96
REMARK 500   OP1    A A  2060     O    LYS F    68              1.97
REMARK 500   O2'    U A  2712     O5'    A A  2712A             1.97
REMARK 500   N2     G A  1899     N4     C A  1902              1.99
REMARK 500   O2'    G A  2447     OP2    A A  2448              2.00
REMARK 500   O2'    G A  1252     O4'    A A  1253              2.00
REMARK 500   O2'    G A  1171     O5'    G A  1173              2.01
REMARK 500   O2'    G A   946     O5'    G A   947              2.03
REMARK 500   O2'    G A  1266     O6     G A  2012              2.03
REMARK 500   O2'    A A   222     OP1    A A   223              2.04
REMARK 500   O2'    G A  1653     OP2    A A  1654              2.04
REMARK 500   O2'    A A  2503     OP2    G A  2505              2.06
REMARK 500   O6     G A  1266     OG   SER S    13              2.06
REMARK 500   O2'    C A   654I    O5'    A A   654J             2.07
REMARK 500   O2'    A A   654J    O5'    C A   654K             2.07
REMARK 500   OD2  ASP V   148     O    VAL V   174              2.07
REMARK 500   O    LYS 4    38     N    HIS 4    40              2.08
REMARK 500   O2'    G A  1171     O4'    G A  1173              2.08
REMARK 500   O2'    C A   888     OP2    C A   889              2.08
REMARK 500   O2'    G A  2282     OP2    C A  2283              2.10
REMARK 500   O2'    U A   387     C5'    G A   388              2.11
REMARK 500   O2'    G A   508     OP1    C A   509              2.11
REMARK 500   O2'    U A   387     O5'    G A   388              2.11
REMARK 500   CG   PRO V   108     O    VAL V   141              2.11
REMARK 500   O2'    A A    74     OP2    G A    75              2.11
REMARK 500   O2'    A A   782     O    ALA D   225              2.11
REMARK 500   CG1  VAL V   175     CD   PRO V   177              2.12
REMARK 500   O2'    A A  2776     OP2    G A  2777              2.12
REMARK 500   O6     G A   530     OP1    G A  2023              2.12
REMARK 500   N6     A A    84     O2'    G A   102              2.13
REMARK 500   O2'    G A  2110     OP1    C A  2111              2.13
REMARK 500   OE1  GLU V   145     CG1  VAL V   174              2.13
REMARK 500   C2'    A A   821     OP2    G A   946              2.13
REMARK 500
REMARK 500 THIS ENTRY HAS      73 CLOSE CONTACTS
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500  M RES CSSEQI ATM1   RES CSSEQI ATM2   DEVIATION
REMARK 500      A A1342   O3'     G A1343   P      -0.092
REMARK 500      A A1359   C5      A A1359   C6     -0.066
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500  M RES CSSEQI ATM1   ATM2   ATM3
REMARK 500      A A   5   OP1 -  P   -  OP2 ANGL. DEV. =   9.1 DEGREES
REMARK 500      A A   5   O5' -  P   -  OP1 ANGL. DEV. = -10.1 DEGREES
REMARK 500      A A   5   O3' -  P   -  OP2 ANGL. DEV. = -39.6 DEGREES
REMARK 500      A A   5   O3' -  P   -  OP1 ANGL. DEV. = -41.9 DEGREES
REMARK 500      G A  60   N9  -  C1' -  C2' ANGL. DEV. =   8.6 DEGREES
REMARK 500      G A  70   N9  -  C1' -  C2' ANGL. DEV. =  10.4 DEGREES
REMARK 500      G A  83   N9  -  C1' -  C2' ANGL. DEV. =   9.6 DEGREES
REMARK 500      U A 120   N1  -  C1' -  C2' ANGL. DEV. =   8.5 DEGREES
REMARK 500      A A 222   N9  -  C1' -  C2' ANGL. DEV. =  10.4 DEGREES
REMARK 500      G A 301   N9  -  C1' -  C2' ANGL. DEV. =   7.9 DEGREES
REMARK 500      A A 322   C1' -  O4' -  C4' ANGL. DEV. =  -9.0 DEGREES
REMARK 500      A A 322   N9  -  C1' -  C2' ANGL. DEV. =  11.7 DEGREES
REMARK 500      A A 322   O4' -  C1' -  N9  ANGL. DEV. =   5.2 DEGREES
REMARK 500      G A 323   C1' -  O4' -  C4' ANGL. DEV. =  -4.7 DEGREES
REMARK 500      G A 323   O4' -  C1' -  N9  ANGL. DEV. =   6.2 DEGREES
REMARK 500      G A 352   N9  -  C1' -  C2' ANGL. DEV. =   9.1 DEGREES
REMARK 500      A A 371   N9  -  C1' -  C2' ANGL. DEV. =   8.9 DEGREES
REMARK 500      U A 421   N1  -  C1' -  C2' ANGL. DEV. =   8.6 DEGREES
REMARK 500      A A 571   N9  -  C1' -  C2' ANGL. DEV. =   8.5 DEGREES
REMARK 500      G A 573   N9  -  C1' -  C2' ANGL. DEV. =  10.3 DEGREES
REMARK 500      U A 607   N3  -  C4  -  O4  ANGL. DEV. =  -4.6 DEGREES
REMARK 500      U A 607   C5  -  C4  -  O4  ANGL. DEV. =  -5.4 DEGREES
REMARK 500      A A 621   C5  -  C6  -  N6  ANGL. DEV. =  -4.9 DEGREES
REMARK 500      C A 654M  N1  -  C1' -  C2' ANGL. DEV. =  10.7 DEGREES
REMARK 500      G A 654S  N9  -  C1' -  C2' ANGL. DEV. =  -7.5 DEGREES
REMARK 500      A A 788   N9  -  C1' -  C2' ANGL. DEV. =  11.0 DEGREES
REMARK 500      G A 801   N9  -  C1' -  C2' ANGL. DEV. =  10.5 DEGREES
REMARK 500      U A 895   N3  -  C4  -  O4  ANGL. DEV. =  -5.5 DEGREES
REMARK 500      A A1247   N9  -  C1' -  C2' ANGL. DEV. =  10.4 DEGREES
REMARK 500      G A1252   N9  -  C1' -  C2' ANGL. DEV. =  10.4 DEGREES
REMARK 500      A A1302   N9  -  C1' -  C2' ANGL. DEV. =   7.9 DEGREES
REMARK 500      U A1329   N1  -  C1' -  C2' ANGL. DEV. =   9.1 DEGREES
REMARK 500      A A1342   C3' -  O3' -  P   ANGL. DEV. =  20.5 DEGREES
REMARK 500      G A1343   O3' -  P   -  O5' ANGL. DEV. = -11.9 DEGREES
REMARK 500      G A1343   O3' -  P   -  OP1 ANGL. DEV. =  22.0 DEGREES
REMARK 500      A A1359   C3' -  C2' -  C1' ANGL. DEV. =  -8.2 DEGREES
REMARK 500      U A1372   C1' -  O4' -  C4' ANGL. DEV. =  -4.3 DEGREES
REMARK 500      U A1372   C3' -  C2' -  C1' ANGL. DEV. =  -6.2 DEGREES
REMARK 500      U A1372   O4' -  C1' -  N1  ANGL. DEV. =  -6.4 DEGREES
REMARK 500      A A1373   O3' -  P   -  O5' ANGL. DEV. =  11.7 DEGREES
REMARK 500      A A1379   C1' -  O4' -  C4' ANGL. DEV. = -11.5 DEGREES
REMARK 500      A A1379   N9  -  C1' -  C2' ANGL. DEV. =   9.5 DEGREES
REMARK 500      A A1378   C3' -  O3' -  P   ANGL. DEV. =   8.0 DEGREES
REMARK 500      G A1380   O4' -  C1' -  N9  ANGL. DEV. =  -5.1 DEGREES
REMARK 500      G A1385   N9  -  C1' -  C2' ANGL. DEV. =   8.1 DEGREES
REMARK 500      G A1385   O4' -  C1' -  N9  ANGL. DEV. =   4.3 DEGREES
REMARK 500      U A1397   C2' -  C3' -  O3' ANGL. DEV. =  11.6 DEGREES
REMARK 500      C A1428   N1  -  C1' -  C2' ANGL. DEV. =   8.8 DEGREES
REMARK 500      A A1566   N9  -  C1' -  C2' ANGL. DEV. =   9.1 DEGREES
REMARK 500      A A1609   N9  -  C1' -  C2' ANGL. DEV. =   9.0 DEGREES
REMARK 500
REMARK 500 THIS ENTRY HAS      95 ANGLE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500  M RES CSSEQI        PSI       PHI
REMARK 500    VAL D   3      112.53    148.23
REMARK 500    PRO D   8       49.13    -67.54
REMARK 500    SER D  12      -18.54     75.27
REMARK 500    PHE D  21       58.13   -100.40
REMARK 500    GLU D  23       33.43    -90.29
REMARK 500    THR D  25      164.29     42.41
REMARK 500    LYS D  26       23.69    -56.42
REMARK 500    THR D  27     -106.05    -92.98
REMARK 500    GLU D  28      -67.89     99.43
REMARK 500    LEU D  33      -94.57    167.74
REMARK 500    LYS D  35      161.37     76.32
REMARK 500    HIS D  58      149.67    -30.39
REMARK 500    ILE D  64       96.98    -55.85
REMARK 500    LYS D  68       68.67   -154.25
REMARK 500    ARG D  69       -9.17    -51.06
REMARK 500    LYS D  72       50.72    -95.82
REMARK 500    ILE D 106       98.03    -56.89
REMARK 500    ALA D 107      122.75    -37.89
REMARK 500    ALA D 123      136.15    -37.30
REMARK 500    ILE D 125       94.69    -58.33
REMARK 500    VAL D 127      113.69    -36.17
REMARK 500    ARG D 134       -7.63    -58.26
REMARK 500    PRO D 137      108.40    -47.10
REMARK 500    VAL D 138      128.04    -37.64
REMARK 500    HIS D 143     -156.03   -105.57
REMARK 500    ALA D 144       81.93     18.71
REMARK 500    LYS D 150       18.95     51.29
REMARK 500    LYS D 154       -3.44   -143.32
REMARK 500    ALA D 156      106.88     53.76
REMARK 500    ARG D 157       22.55    175.24
REMARK 500    ALA D 158       50.65   -112.84
REMARK 500    ALA D 159      118.58     65.62
REMARK 500    SER D 162      155.98    175.87
REMARK 500    VAL D 196      -85.29     22.04
REMARK 500    ALA D 225       13.35    148.19
REMARK 500    GLU D 237     -159.99    142.56
REMARK 500    ARG D 239     -169.85     47.63
REMARK 500    ALA D 240      141.56    165.92
REMARK 500    PRO D 246      122.10    -38.06
REMARK 500    LEU D 257      105.53    -47.19
REMARK 500    ARG D 263       17.79    -64.81
REMARK 500    SER D 267     -148.66    -62.96
REMARK 500    ARG D 268        6.23     46.38
REMARK 500    ILE D 271       82.09   -154.73
REMARK 500    ALA D 272      153.68     68.43
REMARK 500    LYS E   2      177.55     45.90
REMARK 500    ILE E   4      150.41     69.28
REMARK 500    LYS E   8      -84.34    -67.84
REMARK 500    VAL E   9      -74.79    106.76
REMARK 500    MET E  11      141.57    149.77
REMARK 500
REMARK 500 THIS ENTRY HAS     820 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: PLANAR GROUPS
REMARK 500
REMARK 500 PLANAR GROUPS IN THE FOLLOWING RESIDUES HAVE A TOTAL
REMARK 500 RMS DISTANCE OF ALL ATOMS FROM THE BEST-FIT PLANE
REMARK 500 BY MORE THAN AN EXPECTED VALUE OF 6*RMSD, WITH AN
REMARK 500 RMSD 0.02 ANGSTROMS, OR AT LEAST ONE ATOM HAS
REMARK 500 AN RMSD GREATER THAN THIS VALUE
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500  M RES CSSEQI        RMS     TYPE
REMARK 500      U A  33         0.08    SIDE CHAIN
REMARK 500      U A  50         0.07    SIDE CHAIN
REMARK 500      G A  70         0.09    SIDE CHAIN
REMARK 500      U A  72         0.08    SIDE CHAIN
REMARK 500      A A  74         0.06    SIDE CHAIN
REMARK 500      A A 196         0.06    SIDE CHAIN
REMARK 500      C A 201         0.07    SIDE CHAIN
REMARK 500      A A 227         0.06    SIDE CHAIN
REMARK 500      G A 232         0.05    SIDE CHAIN
REMARK 500      G A 250         0.05    SIDE CHAIN
REMARK 500      U A 305         0.06    SIDE CHAIN
REMARK 500      C A 319         0.07    SIDE CHAIN
REMARK 500      A A 331         0.05    SIDE CHAIN
REMARK 500      G A 352         0.05    SIDE CHAIN
REMARK 500      A A 371         0.05    SIDE CHAIN
REMARK 500      U A 403         0.10    SIDE CHAIN
REMARK 500      U A 441         0.07    SIDE CHAIN
REMARK 500      G A 463         0.06    SIDE CHAIN
REMARK 500      G A 476         0.05    SIDE CHAIN
REMARK 500      G A 481         0.06    SIDE CHAIN
REMARK 500      G A 506         0.06    SIDE CHAIN
REMARK 500      C A 510         0.07    SIDE CHAIN
REMARK 500      U A 566         0.06    SIDE CHAIN
REMARK 500      U A 607         0.31    SIDE CHAIN
REMARK 500      A A 608         0.07    SIDE CHAIN
REMARK 500      G A 642         0.07    SIDE CHAIN
REMARK 500      C A 654G        0.14    SIDE CHAIN
REMARK 500      C A 654M        0.12    SIDE CHAIN
REMARK 500      A A 670         0.06    SIDE CHAIN
REMARK 500      G A 682         0.06    SIDE CHAIN
REMARK 500      C A 683         0.07    SIDE CHAIN
REMARK 500      A A 788         0.08    SIDE CHAIN
REMARK 500      C A 816         0.07    SIDE CHAIN
REMARK 500      C A 817         0.09    SIDE CHAIN
REMARK 500      G A 859         0.08    SIDE CHAIN
REMARK 500      U A 895         0.29    SIDE CHAIN
REMARK 500      U A 913         0.09    SIDE CHAIN
REMARK 500      U A 930         0.08    SIDE CHAIN
REMARK 500      U A 943         0.06    SIDE CHAIN
REMARK 500      G A1025         0.06    SIDE CHAIN
REMARK 500      U A1082         0.18    SIDE CHAIN
REMARK 500      A A1143         0.08    SIDE CHAIN
REMARK 500      U A1159         0.07    SIDE CHAIN
REMARK 500      G A1215         0.06    SIDE CHAIN
REMARK 500      A A1242         0.05    SIDE CHAIN
REMARK 500      A A1247         0.06    SIDE CHAIN
REMARK 500      U A1249         0.19    SIDE CHAIN
REMARK 500      G A1250         0.05    SIDE CHAIN
REMARK 500      G A1252         0.09    SIDE CHAIN
REMARK 500      U A1294         0.08    SIDE CHAIN
REMARK 500
REMARK 500 THIS ENTRY HAS     115 PLANE DEVIATIONS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: 3I8G   RELATED DB: PDB
REMARK 900 30S SUBUNIT
REMARK 900 RELATED ID: 3I8H   RELATED DB: PDB
REMARK 900 30S SUBUNIT OF MOLECULE A
REMARK 900 RELATED ID: 3I8I   RELATED DB: PDB
REMARK 900 70S SUBUNIT OF MOLECULE B
DBREF1 3I8F A    1  2902  GB                   AP008226.1
DBREF2 3I8F A     AP008226                         9240       12150
DBREF  3I8F B    0   119  GB     X01554.1 X01554           1    121
DBREF  3I8F D    1   276  UNP    P60405   RL2_THET8        1    276
DBREF  3I8F E    1   206  UNP    Q5SHN8   RL3_THET8        1    206
DBREF  3I8F F    1   210  UNP    Q5SHN9   RL4_THET8        1    210
DBREF  3I8F G    1   182  UNP    Q5SHQ0   RL5_THET8        1    182
DBREF  3I8F H    1   180  UNP    Q5SHQ3   RL6_THET8        1    180
DBREF  3I8F K    1   148  UNP    Q5SLQ1   RL9_THET8        1    148
DBREF  3I8F M    1   140  UNP    P60488   RL13_THET8       1    140
DBREF  3I8F N    1   122  UNP    Q5SHP8   RL14_THET8       1    122
DBREF  3I8F O    1   150  UNP    Q5SHQ7   RL15_THET8       1    150
DBREF  3I8F P    1   141  UNP    P60489   RL16_THET8       1    141
DBREF  3I8F 0    1   118  UNP    Q9Z9H5   RL17_THET8       1    118
DBREF  3I8F Q    1   112  UNP    Q5SHQ4   RL18_THET8       1    112
DBREF  3I8F R    1   146  UNP    P60490   RL19_THET8       1    146
DBREF  3I8F 1    1   118  UNP    P60491   RL20_THET8       1    118
DBREF  3I8F 2    1   101  UNP    P60492   RL21_THET8       1    101
DBREF  3I8F S    1   113  UNP    Q5SHP3   RL22_THET8       1    113
DBREF  3I8F T    1    96  UNP    Q5SHP0   RL23_THET8       1     96
DBREF  3I8F U    1   110  UNP    Q5SHP9   RL24_THET8       1    110
DBREF  3I8F V    1   206  UNP    Q5SHZ1   RL25_THET8       1    206
DBREF  3I8F 3    1    85  UNP    P60493   RL27_THET8       1     85
DBREF  3I8F Z    1    98  UNP    P60494   RL28_THET8       1     98
DBREF  3I8F W    1    72  UNP    Q5SHP6   RL29_THET8       1     72
DBREF  3I8F X    1    60  UNP    Q5SHQ6   RL30_THET8       1     60
DBREF  3I8F 4    1    71  UNP    Q5SJE1   RL31_THET8       1     71
DBREF  3I8F 5    1    60  UNP    P80339   RL32_THET8       1     60
DBREF  3I8F 6    1    54  UNP    P35871   RL33_THET8       1     54
DBREF  3I8F 7    1    49  UNP    P80340   RL34_THET8       1     49
DBREF  3I8F 8    1    65  UNP    Q5SKU1   RL35_THET8       1     65
SEQADV 3I8F     A       GB   AP008226.   U  9395 DELETION
SEQADV 3I8F     A       GB   AP008226.   U  9396 DELETION
SEQADV 3I8F   A A  654A GB   AP008226.   G  9919 CONFLICT
SEQADV 3I8F   C A  654E GB   AP008226.   G  9923 CONFLICT
SEQADV 3I8F   G A  654P GB   AP008226.   C  9934 CONFLICT
SEQADV 3I8F   A A  654T GB   AP008226.   C  9938 CONFLICT
SEQADV 3I8F   U A 1058  GB   AP008226.   G 10343 CONFLICT
SEQADV 3I8F   A A 1080  GB   AP008226.   C 10365 CONFLICT
SEQADV 3I8F   A B    1M GB   X01554.1            INSERTION
SEQRES   1 A 2909    G   G   U   C   A   A   G   A   U   G   G   U   A
SEQRES   2 A 2909    A   G   G   G   C   C   C   A   C   G   G   U   G
SEQRES   3 A 2909    G   A   U   G   C   C   U   C   G   G   C   A   C
SEQRES   4 A 2909    C   C   G   A   G   C   C   G   A   U   G   A   A
SEQRES   5 A 2909    G   G   A   C   G   U   G   G   C   U   A   C   C
SEQRES   6 A 2909    U   G   C   G   A   U   A   A   G   C   C   A   G
SEQRES   7 A 2909    G   G   G   G   A   G   C   C   G   G   U   A   G
SEQRES   8 A 2909    C   G   G   G   C   G   U   G   G   A   U   C   C
SEQRES   9 A 2909    C   U   G   G   A   U   G   U   C   C   G   A   A
SEQRES  10 A 2909    U   G   G   G   G   G   A   A   C   C   C   G   G
SEQRES  11 A 2909    C   C   G   G   C   G   G   G   A   A   C   G   C
SEQRES  12 A 2909    C   G   G   U   C   A   C   C   G   C   G   C   U
SEQRES  13 A 2909    U   G   C   G   C   G   G   G   G   G   G   A   A
SEQRES  14 A 2909    C   C   U   G   G   G   G   A   A   C   U   G   A
SEQRES  15 A 2909    A   A   C   A   U   C   U   C   A   G   U   A   C
SEQRES  16 A 2909    C   C   A   G   A   G   G   A   G   A   G   G   A
SEQRES  17 A 2909    A   A   G   A   G   A   A   A   U   C   G   A   C
SEQRES  18 A 2909    U   C   C   C   U   G   A   G   U   A   G   C   G
SEQRES  19 A 2909    G   C   G   A   G   C   G   A   A   A   G   G   G
SEQRES  20 A 2909    G   A   C   C   A   G   C   C   U   A   A   A   C
SEQRES  21 A 2909    C   G   U   C   C   G   G   C   U   U   G   U   C
SEQRES  22 A 2909    C   G   G   G   C   G   G   G   G   U   C   G   U
SEQRES  23 A 2909    G   G   G   G   C   C   C   U   C   G   G   A   C
SEQRES  24 A 2909    A   C   C   G   A   A   U   C   C   C   C   A   G
SEQRES  25 A 2909    C   C   U   A   G   C   C   G   A   A   G   C   U
SEQRES  26 A 2909    G   U   U   G   G   G   A   A   G   C   A   G   C
SEQRES  27 A 2909    G   C   C   A   G   A   G   A   G   G   G   U   G
SEQRES  28 A 2909    A   A   A   G   C   C   C   C   G   U   A   G   G
SEQRES  29 A 2909    C   G   A   A   A   G   G   U   G   G   G   G   G
SEQRES  30 A 2909    G   A   U   A   G   G   U   G   A   G   G   G   U
SEQRES  31 A 2909    A   C   C   C   G   A   G   U   A   C   C   C   C
SEQRES  32 A 2909    G   U   G   G   U   U   C   G   U   G   G   A   G
SEQRES  33 A 2909    C   C   A   U   G   G   G   G   G   A   A   U   C
SEQRES  34 A 2909    U   G   G   G   C   G   G   A   C   C   A   C   C
SEQRES  35 A 2909    G   C   C   U   A   A   G   G   C   U   A   A   G
SEQRES  36 A 2909    U   A   C   U   C   C   G   G   G   U   G   A   C
SEQRES  37 A 2909    C   G   A   U   A   G   C   G   C   A   C   C   A
SEQRES  38 A 2909    G   U   A   C   C   G   U   G   A   G   G   G   A
SEQRES  39 A 2909    A   A   G   G   U   G   A   A   A   A   G   A   A
SEQRES  40 A 2909    C   C   C   C   G   G   G   A   G   G   G   G   A
SEQRES  41 A 2909    G   U   G   A   A   A   U   A   G   A   G   C   C
SEQRES  42 A 2909    U   G   A   A   A   C   C   G   U   G   G   G   C
SEQRES  43 A 2909    U   U   A   C   A   A   G   C   A   G   U   C   A
SEQRES  44 A 2909    C   G   G   C   C   C   C   G   C   A   A   G   G
SEQRES  45 A 2909    G   G   U   U   G   U   G   G   C   G   U   G   C
SEQRES  46 A 2909    C   U   A   U   U   G   A   A   G   C   A   U   G
SEQRES  47 A 2909    A   G   C   C   G   G   C   G   A   C   U   C   A
SEQRES  48 A 2909    C   G   G   U   C   G   U   G   G   G   C   G   A
SEQRES  49 A 2909    G   C   U   U   A   A   G   C   C   G   U   U   G
SEQRES  50 A 2909    A   G   G   C   G   G   A   G   G   C   G   U   A
SEQRES  51 A 2909    G   G   G   A   A   A   C   C   G   A   G   U   C
SEQRES  52 A 2909    C   G   A   A   C   A   G   G   G   C   G   C   A
SEQRES  53 A 2909    A   A   C   G   G   C   C   C   G   C   A   C   G
SEQRES  54 A 2909    C   G   G   G   C   C   G   A   A   A   A   G   U
SEQRES  55 A 2909    C   C   G   C   G   G   C   C   G   U   G   G   A
SEQRES  56 A 2909    C   C   C   G   A   A   A   C   C   G   G   G   C
SEQRES  57 A 2909    G   A   G   C   U   A   G   C   C   C   U   G   G
SEQRES  58 A 2909    C   C   A   G   G   G   U   G   A   A   G   C   U
SEQRES  59 A 2909    G   G   G   G   U   G   A   G   A   C   C   C   A
SEQRES  60 A 2909    G   U   G   G   A   G   G   C   C   C   G   A   A
SEQRES  61 A 2909    C   C   G   G   U   G   G   G   G   G   A   U   G
SEQRES  62 A 2909    C   A   A   A   C   C   C   C   U   C   G   G   A
SEQRES  63 A 2909    U   G   A   G   C   U   G   G   G   G   C   U   A
SEQRES  64 A 2909    G   G   A   G   U   G   A   A   A   A   G   C   U
SEQRES  65 A 2909    A   A   C   C   G   A   G   C   C   C   G   G   A
SEQRES  66 A 2909    G   A   U   A   G   C   U   G   G   U   U   C   U
SEQRES  67 A 2909    C   C   C   C   G   A   A   A   U   G   A   C   U
SEQRES  68 A 2909    U   U   A   G   G   G   U   C   A   G   C   C   U
SEQRES  69 A 2909    C   A   G   G   C   G   C   U   G   A   C   U   G
SEQRES  70 A 2909    G   G   G   C   C   U   G   U   A   G   A   G   C
SEQRES  71 A 2909    A   C   U   G   A   U   A   G   G   G   C   U   A
SEQRES  72 A 2909    G   G   G   G   G   C   C   C   A   C   C   A   G
SEQRES  73 A 2909    C   C   U   A   C   C   A   A   A   C   C   C   U
SEQRES  74 A 2909    G   U   C   A   A   A   C   U   C   C   G   A   A
SEQRES  75 A 2909    G   G   G   U   C   C   C   A   G   G   U   G   G
SEQRES  76 A 2909    A   G   C   C   U   G   G   G   A   G   U   G   A
SEQRES  77 A 2909    G   G   G   C   G   C   G   A   G   C   G   A   U
SEQRES  78 A 2909    A   A   C   G   U   C   C   G   C   G   U   C   C
SEQRES  79 A 2909    G   A   G   C   G   C   G   G   G   A   A   C   A
SEQRES  80 A 2909    A   C   C   G   A   G   A   C   C   G   C   C   A
SEQRES  81 A 2909    G   C   U   A   A   G   G   C   C   C   C   C   A
SEQRES  82 A 2909    A   G   U   C   U   G   G   G   C   U   A   A   G
SEQRES  83 A 2909    U   G   G   U   A   A   A   G   G   A   U   G   U
SEQRES  84 A 2909    G   G   C   G   C   C   G   C   G   A   A   G   A
SEQRES  85 A 2909    C   A   G   C   C   A   G   G   A   U   G   U   U
SEQRES  86 A 2909    G   G   C   U   U   A   G   A   A   G   C   A   G
SEQRES  87 A 2909    C   C   A   U   C   A   U   U   U   A   A   A   G
SEQRES  88 A 2909    A   G   U   G   C   G   U   A   A   U   A   G   C
SEQRES  89 A 2909    U   C   A   C   U   G   G   U   C   G   A   G   U
SEQRES  90 A 2909    G   G   C   G   C   C   G   C   G   C   C   G   A
SEQRES  91 A 2909    A   A   A   U   G   A   U   C   G   G   G   G   C
SEQRES  92 A 2909    U   U   A   A   G   C   C   C   A   G   C   G   C
SEQRES  93 A 2909    C   G   A   A   G   C   U   G   C   G   G   G   U
SEQRES  94 A 2909    C   U   G   G   G   G   G   A   U   G   A   C   C
SEQRES  95 A 2909    C   C   A   G   G   C   G   G   U   A   G   G   G
SEQRES  96 A 2909    G   A   G   C   G   U   U   C   C   C   G   A   U
SEQRES  97 A 2909    G   C   C   G   A   U   G   A   A   G   G   C   C
SEQRES  98 A 2909    G   A   C   C   C   G   C   G   A   G   G   G   C
SEQRES  99 A 2909    G   G   C   U   G   G   A   G   G   U   A   A   G
SEQRES 100 A 2909    G   G   A   A   G   U   G   C   G   A   A   U   G
SEQRES 101 A 2909    C   C   G   G   C   A   U   G   A   G   U   A   A
SEQRES 102 A 2909    C   G   A   U   A   A   A   G   A   G   G   G   U
SEQRES 103 A 2909    G   A   G   A   A   U   C   C   C   U   C   U   C
SEQRES 104 A 2909    G   C   C   G   U   A   A   G   C   C   C   A   A
SEQRES 105 A 2909    G   G   G   U   U   C   C   U   A   C   G   C   A
SEQRES 106 A 2909    A   U   G   G   U   C   G   U   C   A   G   C   G
SEQRES 107 A 2909    U   A   G   G   G   U   U   A   G   G   C   G   G
SEQRES 108 A 2909    G   A   C   C   U   A   A   G   G   U   G   A   A
SEQRES 109 A 2909    G   C   C   G   A   A   A   G   G   C   G   U   A
SEQRES 110 A 2909    G   C   C   G   A   A   G   G   G   C   A   G   C
SEQRES 111 A 2909    C   G   G   U   U   A   A   U   A   U   U   C   C
SEQRES 112 A 2909    G   G   C   C   C   U   U   C   C   C   G   C   A
SEQRES 113 A 2909    G   G   U   G   C   G   A   U   G   G   G   G   G
SEQRES 114 A 2909    G   A   C   G   C   U   C   U   A   G   G   C   U
SEQRES 115 A 2909    A   G   G   G   G   G   A   C   C   G   G   A   G
SEQRES 116 A 2909    C   C   A   U   G   G   A   C   G   A   G   C   C
SEQRES 117 A 2909    C   G   G   C   C   A   G   A   A   G   C   G   C
SEQRES 118 A 2909    A   G   G   G   U   G   G   G   A   G   G   U   A
SEQRES 119 A 2909    G   G   C   A   A   A   U   C   C   G   C   C   U
SEQRES 120 A 2909    C   C   C   A   A   C   A   A   G   C   U   C   U
SEQRES 121 A 2909    G   C   G   U   G   G   U   G   G   G   G   A   A
SEQRES 122 A 2909    G   C   C   C   G   U   A   C   G   G   G   U   G
SEQRES 123 A 2909    A   C   A   A   C   C   C   C   C   C   G   A   A
SEQRES 124 A 2909    G   C   C   A   G   G   G   A   G   C   C   A   A
SEQRES 125 A 2909    G   A   A   A   A   G   C   C   U   C   U   A   A
SEQRES 126 A 2909    G   C   A   C   A   A   C   C   U   G   C   G   G
SEQRES 127 A 2909    G   A   A   C   C   C   G   U   A   C   C   G   C
SEQRES 128 A 2909    A   A   A   C   C   G   A   C   A   C   A   G   G
SEQRES 129 A 2909    U   G   G   G   C   G   G   G   U   G   C   A   A
SEQRES 130 A 2909    G   A   G   C   A   C   U   C   A   G   G   C   G
SEQRES 131 A 2909    C   G   C   G   G   G   A   G   A   A   C   C   C
SEQRES 132 A 2909    U   C   G   C   C   A   A   G   G   A   A   C   U
SEQRES 133 A 2909    C   U   G   C   A   A   G   U   U   G   G   C   C
SEQRES 134 A 2909    C   C   G   U   A   A   C   U   U   C   G   G   G
SEQRES 135 A 2909    A   G   A   A   G   G   G   G   U   G   C   U   C
SEQRES 136 A 2909    C   C   U   G   G   G   G   U   G   A   U   G   A
SEQRES 137 A 2909    G   C   C   C   C   G   G   G   G   A   G   C   C
SEQRES 138 A 2909    G   C   A   G   U   G   A   A   C   A   G   G   C
SEQRES 139 A 2909    U   C   U   G   G   C   G   A   C   U   G   U   U
SEQRES 140 A 2909    U   A   C   C   A   A   A   A   A   C   A   C   A
SEQRES 141 A 2909    G   C   U   C   U   C   U   G   C   G   A   A   C
SEQRES 142 A 2909    U   C   G   U   A   A   G   A   G   G   A   G   G
SEQRES 143 A 2909    U   A   U   A   G   G   G   A   G   C   G   A   C
SEQRES 144 A 2909    G   C   U   U   G   C   C   C   G   G   U   G   C
SEQRES 145 A 2909    C   G   G   A   A   G   G   U   C   A   A   G   G
SEQRES 146 A 2909    G   G   A   G   G   G   G   U   G   C   A   A   G
SEQRES 147 A 2909    C   C   C   C   G   A   A   C   C   G   A   A   G
SEQRES 148 A 2909    C   C   C   C   G   G   U   G   A   A   C   G   G
SEQRES 149 A 2909    C   G   G   C   C   G   U   A   A   C   U   A   U
SEQRES 150 A 2909    A   A   C   G   G   U   C   C   U   A   A   G   G
SEQRES 151 A 2909    U   A   G   C   G   A   A   A   U   U   C   C   U
SEQRES 152 A 2909    U   G   U   C   G   G   G   U   A   A   G   U   U
SEQRES 153 A 2909    C   C   G   A   C   C   U   G   C   A   C   G   A
SEQRES 154 A 2909    A   A   A   G   C   G   U   A   A   C   G   A   C
SEQRES 155 A 2909    C   G   G   A   G   C   G   C   U   G   U   C   U
SEQRES 156 A 2909    C   G   G   C   G   A   G   G   G   A   C   C   C
SEQRES 157 A 2909    G   G   U   G   A   A   A   U   U   G   A   A   C
SEQRES 158 A 2909    U   G   G   C   C   G   U   G   A   A   G   A   U
SEQRES 159 A 2909    G   C   G   G   C   C   U   A   C   C   C   G   U
SEQRES 160 A 2909    G   G   C   A   G   G   A   C   G   A   A   A   A
SEQRES 161 A 2909    G   A   C   C   C   C   G   U   G   G   A   G   C
SEQRES 162 A 2909    U   U   U   A   C   U   G   C   A   G   C   C   U
SEQRES 163 A 2909    G   G   U   G   U   U   G   G   C   U   C   U   U
SEQRES 164 A 2909    G   G   U   C   G   C   G   C   C   U   G   C   G
SEQRES 165 A 2909    U   A   G   G   A   U   A   G   G   U   G   G   G
SEQRES 166 A 2909    A   G   C   C   U   G   U   G   A   A   C   C   C
SEQRES 167 A 2909    C   C   G   C   C   U   C   C   G   G   G   U   G
SEQRES 168 A 2909    G   G   G   G   G   G   A   G   G   C   G   C   C
SEQRES 169 A 2909    G   G   U   G   A   A   A   U   A   C   C   A   C
SEQRES 170 A 2909    C   C   U   G   G   C   G   C   G   G   C   U   G
SEQRES 171 A 2909    G   G   G   G   C   C   U   A   A   C   C   C   U
SEQRES 172 A 2909    C   G   G   A   U   G   G   G   G   G   G   A   C
SEQRES 173 A 2909    A   G   C   G   C   U   U   G   G   C   G   G   G
SEQRES 174 A 2909    C   A   G   U   U   U   G   A   C   U   G   G   G
SEQRES 175 A 2909    G   C   G   G   U   C   G   C   C   U   C   C   U
SEQRES 176 A 2909    A   A   A   A   G   G   U   A   A   C   G   G   A
SEQRES 177 A 2909    G   G   C   G   C   C   C   A   A   A   G   G   U
SEQRES 178 A 2909    C   C   C   C   U   C   A   G   G   C   G   G   G
SEQRES 179 A 2909    A   C   G   G   A   A   A   U   C   C   G   C   C
SEQRES 180 A 2909    G   G   A   G   A   G   C   G   C   A   A   G   G
SEQRES 181 A 2909    G   U   A   G   A   A   G   G   G   G   G   C   C
SEQRES 182 A 2909    U   G   A   C   U   G   C   G   A   G   G   C   C
SEQRES 183 A 2909    U   G   C   A   A   G   C   C   G   A   G   C   A
SEQRES 184 A 2909    G   G   G   G   C   G   A   A   A   G   C   C   G
SEQRES 185 A 2909    G   G   C   C   U   A   G   U   G   A   A   C   C
SEQRES 186 A 2909    G   G   U   G   G   U   C   C   C   G   U   G   U
SEQRES 187 A 2909    G   G   A   A   G   G   G   C   C   A   U   C   G
SEQRES 188 A 2909    A   U   C   A   A   C   G   G   A   U   A   A   A
SEQRES 189 A 2909    A   G   U   U   A   C   C   C   C   G   G   G   G
SEQRES 190 A 2909    A   U   A   A   C   A   G   G   C   U   G   A   U
SEQRES 191 A 2909    C   U   C   C   C   C   C   G   A   G   C   G   U
SEQRES 192 A 2909    C   C   A   C   A   G   C   G   G   C   G   G   G
SEQRES 193 A 2909    G   A   G   G   U   U   U   G   G   C   A   C   C
SEQRES 194 A 2909    U   C   G   A   U   G   U   C   G   G   C   U   C
SEQRES 195 A 2909    G   U   C   G   C   A   U   C   C   U   G   G   G
SEQRES 196 A 2909    G   C   U   G   A   A   G   A   A   G   G   U   C
SEQRES 197 A 2909    C   C   A   A   G   G   G   U   U   G   G   G   C
SEQRES 198 A 2909    U   G   U   U   C   G   C   C   C   A   U   U   A
SEQRES 199 A 2909    A   A   G   C   G   G   C   A   C   G   C   G   A
SEQRES 200 A 2909    G   C   U   G   G   G   U   U   C   A   G   A   A
SEQRES 201 A 2909    C   G   U   C   G   U   G   A   G   A   C   A   G
SEQRES 202 A 2909    U   U   C   G   G   U   C   U   C   U   A   U   C
SEQRES 203 A 2909    C   G   C   C   A   C   G   G   G   C   G   C   A
SEQRES 204 A 2909    G   G   A   G   G   C   U   U   G   A   G   G   G
SEQRES 205 A 2909    G   G   G   C   U   C   U   U   C   C   U   A   G
SEQRES 206 A 2909    U   A   C   G   A   G   A   G   G   A   C   C   G
SEQRES 207 A 2909    G   A   A   G   G   G   A   C   G   C   A   C   C
SEQRES 208 A 2909    U   C   U   G   G   U   U   U   C   C   C   A   G
SEQRES 209 A 2909    C   U   G   U   C   C   C   U   C   C   A   G   G
SEQRES 210 A 2909    G   G   C   A   U   A   A   G   C   U   G   G   G
SEQRES 211 A 2909    U   A   G   C   C   A   U   G   U   G   C   G   G
SEQRES 212 A 2909    A   A   G   G   G   A   U   A   A   C   C   G   C
SEQRES 213 A 2909    U   G   A   A   A   G   C   A   U   C   U   A   A
SEQRES 214 A 2909    G   C   G   G   G   A   A   G   C   C   C   G   C
SEQRES 215 A 2909    C   C   C   A   A   G   A   U   G   A   G   G   C
SEQRES 216 A 2909    C   U   C   C   C   A   C   G   G   C   G   U   C
SEQRES 217 A 2909    A   A   G   C   C   G   G   U   A   A   G   G   A
SEQRES 218 A 2909    C   C   C   G   G   G   A   A   G   A   C   C   A
SEQRES 219 A 2909    C   C   C   G   G   U   G   G   A   U   G   G   G
SEQRES 220 A 2909    C   C   G   G   G   G   G   U   G   U   A   A   G
SEQRES 221 A 2909    C   G   C   C   G   C   G   A   G   G   C   G   U
SEQRES 222 A 2909    U   G   A   G   C   C   G   A   C   C   G   G   U
SEQRES 223 A 2909    C   C   C   A   A   U   C   G   U   C   C   G   A
SEQRES 224 A 2909    G   G   U   C   U   U   G   A   C   C
SEQRES   1 B  122    A   A   U   C   C   C   C   C   G   U   G   C   C
SEQRES   2 B  122    C   A   U   A   G   C   G   G   C   G   U   G   G
SEQRES   3 B  122    A   A   C   C   A   C   C   C   G   U   U   C   C
SEQRES   4 B  122    C   A   U   U   C   C   G   A   A   C   A   C   G
SEQRES   5 B  122    G   A   A   G   U   G   A   A   A   C   G   C   G
SEQRES   6 B  122    C   C   A   G   C   G   C   C   G   A   U   G   G
SEQRES   7 B  122    U   A   C   U   G   G   G   C   G   G   G   C   G
SEQRES   8 B  122    A   C   C   G   C   C   U   G   G   G   A   G   A
SEQRES   9 B  122    G   U   A   G   G   U   C   G   G   U   G   C   G
SEQRES  10 B  122    G   G   G   G   A
SEQRES   1 D  276  MET ALA VAL LYS LYS PHE LYS PRO TYR THR PRO SER ARG
SEQRES   2 D  276  ARG PHE MET THR VAL ALA ASP PHE SER GLU ILE THR LYS
SEQRES   3 D  276  THR GLU PRO GLU LYS SER LEU VAL LYS PRO LEU LYS LYS
SEQRES   4 D  276  THR GLY GLY ARG ASN ASN GLN GLY ARG ILE THR VAL ARG
SEQRES   5 D  276  PHE ARG GLY GLY GLY HIS LYS ARG LEU TYR ARG ILE ILE
SEQRES   6 D  276  ASP PHE LYS ARG TRP ASP LYS VAL GLY ILE PRO ALA LYS
SEQRES   7 D  276  VAL ALA ALA ILE GLU TYR ASP PRO ASN ARG SER ALA ARG
SEQRES   8 D  276  ILE ALA LEU LEU HIS TYR VAL ASP GLY GLU LYS ARG TYR
SEQRES   9 D  276  ILE ILE ALA PRO ASP GLY LEU GLN VAL GLY GLN GLN VAL
SEQRES  10 D  276  VAL ALA GLY PRO ASP ALA PRO ILE GLN VAL GLY ASN ALA
SEQRES  11 D  276  LEU PRO LEU ARG PHE ILE PRO VAL GLY THR VAL VAL HIS
SEQRES  12 D  276  ALA VAL GLU LEU GLU PRO LYS LYS GLY ALA LYS LEU ALA
SEQRES  13 D  276  ARG ALA ALA GLY THR SER ALA GLN ILE GLN GLY ARG GLU
SEQRES  14 D  276  GLY ASP TYR VAL ILE LEU ARG LEU PRO SER GLY GLU LEU
SEQRES  15 D  276  ARG LYS VAL HIS GLY GLU CYS TYR ALA THR VAL GLY ALA
SEQRES  16 D  276  VAL GLY ASN ALA ASP HIS LYS ASN ILE VAL LEU GLY LYS
SEQRES  17 D  276  ALA GLY ARG SER ARG TRP LEU GLY ARG ARG PRO HIS VAL
SEQRES  18 D  276  ARG GLY ALA ALA MET ASN PRO VAL ASP HIS PRO HIS GLY
SEQRES  19 D  276  GLY GLY GLU GLY ARG ALA PRO ARG GLY ARG PRO PRO ALA
SEQRES  20 D  276  SER PRO TRP GLY TRP GLN THR LYS GLY LEU LYS THR ARG
SEQRES  21 D  276  LYS ARG ARG LYS PRO SER SER ARG PHE ILE ILE ALA ARG
SEQRES  22 D  276  ARG LYS LYS
SEQRES   1 E  206  MET LYS GLY ILE LEU GLY VAL LYS VAL GLY MET THR ARG
SEQRES   2 E  206  ILE PHE ARG ASP ASP ARG ALA VAL PRO VAL THR VAL ILE
SEQRES   3 E  206  LEU ALA GLY PRO CYS PRO VAL VAL GLN ARG ARG THR PRO
SEQRES   4 E  206  GLU LYS ASP GLY TYR THR ALA VAL GLN LEU GLY PHE LEU
SEQRES   5 E  206  PRO GLN ASN PRO LYS ARG VAL ASN ARG PRO LEU LYS GLY
SEQRES   6 E  206  HIS PHE ALA LYS ALA GLY VAL GLU PRO VAL ARG ILE LEU
SEQRES   7 E  206  ARG GLU ILE ARG ASP PHE ASN PRO GLU GLY ASP THR VAL
SEQRES   8 E  206  THR VAL GLU ILE PHE LYS PRO GLY GLU ARG VAL ASP VAL
SEQRES   9 E  206  THR GLY THR SER LYS GLY ARG GLY PHE ALA GLY VAL MET
SEQRES  10 E  206  LYS ARG TRP ASN PHE ALA GLY GLY PRO ASP SER HIS GLY
SEQRES  11 E  206  ALA HIS LYS ILE HIS ARG HIS PRO GLY SER ILE GLY ASN
SEQRES  12 E  206  ARG LYS THR PRO GLY ARG VAL TYR LYS GLY LYS LYS MET
SEQRES  13 E  206  ALA GLY HIS TYR GLY ALA GLU ARG VAL THR VAL MET ASN
SEQRES  14 E  206  LEU GLU VAL VAL ASP VAL ILE PRO GLU GLU ASN LEU LEU
SEQRES  15 E  206  LEU VAL LYS GLY ALA VAL PRO GLY PRO ASN GLY GLY LEU
SEQRES  16 E  206  VAL ILE VAL ARG GLU THR LYS LYS ALA ALA LYS
SEQRES   1 F  210  MET LYS GLU VAL ALA VAL TYR GLN ILE PRO VAL LEU SER
SEQRES   2 F  210  PRO SER GLY ARG ARG GLU LEU ALA ALA ASP LEU PRO ALA
SEQRES   3 F  210  GLU ILE ASN PRO HIS LEU LEU TRP GLU VAL VAL ARG TRP
SEQRES   4 F  210  GLN LEU ALA LYS ARG ARG ARG GLY THR ALA SER THR LYS
SEQRES   5 F  210  THR ARG GLY GLU VAL ALA TYR SER GLY ARG LYS ILE TRP
SEQRES   6 F  210  PRO GLN LYS HIS THR GLY ARG ALA ARG HIS GLY ASP ILE
SEQRES   7 F  210  GLY ALA PRO ILE PHE VAL GLY GLY GLY VAL VAL PHE GLY
SEQRES   8 F  210  PRO LYS PRO ARG ASP TYR SER TYR THR LEU PRO LYS LYS
SEQRES   9 F  210  VAL ARG LYS LYS GLY LEU ALA MET ALA VAL ALA ASP ARG
SEQRES  10 F  210  ALA ARG GLU GLY LYS LEU LEU LEU VAL GLU ALA PHE ALA
SEQRES  11 F  210  GLY VAL ASN GLY LYS THR LYS GLU PHE LEU ALA TRP ALA
SEQRES  12 F  210  LYS GLU ALA GLY LEU ASP GLY SER GLU SER VAL LEU LEU
SEQRES  13 F  210  VAL THR GLY ASN GLU LEU VAL ARG ARG ALA ALA ARG ASN
SEQRES  14 F  210  LEU PRO TRP VAL VAL THR LEU ALA PRO GLU GLY LEU ASN
SEQRES  15 F  210  VAL TYR ASP ILE VAL ARG THR GLU ARG LEU VAL MET ASP
SEQRES  16 F  210  LEU ASP ALA TRP GLU VAL PHE GLN ASN ARG ILE GLY GLY
SEQRES  17 F  210  GLU ALA
SEQRES   1 G  182  MET PRO LEU ASP VAL ALA LEU LYS ARG LYS TYR TYR GLU
SEQRES   2 G  182  GLU VAL ARG PRO GLU LEU ILE ARG ARG PHE GLY TYR GLN
SEQRES   3 G  182  ASN VAL TRP GLU VAL PRO ARG LEU GLU LYS VAL VAL ILE
SEQRES   4 G  182  ASN GLN GLY LEU GLY GLU ALA LYS GLU ASP ALA ARG ILE
SEQRES   5 G  182  LEU GLU LYS ALA ALA GLN GLU LEU ALA LEU ILE THR GLY
SEQRES   6 G  182  GLN LYS PRO ALA VAL THR ARG ALA LYS LYS SER ILE SER
SEQRES   7 G  182  ASN PHE LYS LEU ARG LYS GLY MET PRO ILE GLY LEU ARG
SEQRES   8 G  182  VAL THR LEU ARG ARG ASP ARG MET TRP ILE PHE LEU GLU
SEQRES   9 G  182  LYS LEU LEU ASN VAL ALA LEU PRO ARG ILE ARG ASP PHE
SEQRES  10 G  182  ARG GLY LEU ASN PRO ASN SER PHE ASP GLY ARG GLY ASN
SEQRES  11 G  182  TYR ASN LEU GLY LEU ARG GLU GLN LEU ILE PHE PRO GLU
SEQRES  12 G  182  ILE THR TYR ASP MET VAL ASP ALA LEU ARG GLY MET ASP
SEQRES  13 G  182  ILE ALA VAL VAL THR THR ALA GLU THR ASP GLU GLU ALA
SEQRES  14 G  182  ARG ALA LEU LEU GLU LEU LEU GLY PHE PRO PHE ARG LYS
SEQRES   1 H  180  MET SER ARG ILE GLY ARG LEU PRO ILE PRO VAL PRO LYS
SEQRES   2 H  180  GLY VAL SER VAL GLU VAL ALA PRO GLY ARG VAL LYS VAL
SEQRES   3 H  180  LYS GLY PRO LYS GLY GLU LEU GLU VAL PRO VAL SER PRO
SEQRES   4 H  180  GLU MET ARG VAL VAL VAL GLU GLU GLY VAL VAL ARG VAL
SEQRES   5 H  180  GLU ARG PRO SER ASP GLU ARG ARG HIS LYS SER LEU HIS
SEQRES   6 H  180  GLY LEU THR ARG THR LEU ILE ALA ASN ALA VAL LYS GLY
SEQRES   7 H  180  VAL SER GLU GLY TYR SER LYS GLU LEU LEU ILE LYS GLY
SEQRES   8 H  180  ILE GLY TYR ARG ALA ARG LEU VAL GLY ARG ALA LEU GLU
SEQRES   9 H  180  LEU THR VAL GLY PHE SER HIS PRO VAL VAL VAL GLU PRO
SEQRES  10 H  180  PRO GLU GLY ILE THR PHE GLU VAL PRO GLU PRO THR ARG
SEQRES  11 H  180  VAL ARG VAL SER GLY ILE ASP LYS GLN LYS VAL GLY GLN
SEQRES  12 H  180  VAL ALA ALA ASN ILE ARG ALA ILE ARG LYS PRO SER ALA
SEQRES  13 H  180  TYR HIS GLU LYS GLY ILE TYR TYR ALA GLY GLU PRO VAL
SEQRES  14 H  180  ARG LEU LYS PRO GLY LYS ALA GLY ALA LYS LYS
SEQRES   1 K  148  MET LYS VAL ILE LEU LEU GLU PRO LEU GLU ASN LEU GLY
SEQRES   2 K  148  ASP VAL GLY GLN VAL VAL ASP VAL LYS PRO GLY TYR ALA
SEQRES   3 K  148  ARG ASN TYR LEU LEU PRO ARG GLY LEU ALA VAL LEU ALA
SEQRES   4 K  148  THR GLU SER ASN LEU LYS ALA LEU GLU ALA ARG ILE ARG
SEQRES   5 K  148  ALA GLN ALA LYS ARG LEU ALA GLU ARG LYS ALA GLU ALA
SEQRES   6 K  148  GLU ARG LEU LYS GLU ILE LEU GLU ASN LEU THR LEU THR
SEQRES   7 K  148  ILE PRO VAL ARG ALA GLY GLU THR LYS ILE TYR GLY SER
SEQRES   8 K  148  VAL THR ALA LYS ASP ILE ALA GLU ALA LEU SER ARG GLN
SEQRES   9 K  148  HIS GLY VAL THR ILE ASP PRO LYS ARG LEU ALA LEU GLU
SEQRES  10 K  148  LYS PRO ILE LYS GLU LEU GLY GLU TYR VAL LEU THR TYR
SEQRES  11 K  148  LYS PRO HIS PRO GLU VAL PRO ILE GLN LEU LYS VAL SER
SEQRES  12 K  148  VAL VAL ALA GLN GLU
SEQRES   1 M  140  MET LYS THR TYR VAL PRO LYS GLN VAL GLU PRO ARG TRP
SEQRES   2 M  140  VAL LEU ILE ASP ALA GLU GLY LYS THR LEU GLY ARG LEU
SEQRES   3 M  140  ALA THR LYS ILE ALA THR LEU LEU ARG GLY LYS HIS ARG
SEQRES   4 M  140  PRO ASP TRP THR PRO ASN VAL ALA MET GLY ASP PHE VAL
SEQRES   5 M  140  VAL VAL VAL ASN ALA ASP LYS ILE ARG VAL THR GLY LYS
SEQRES   6 M  140  LYS LEU GLU GLN LYS ILE TYR THR ARG TYR SER GLY TYR
SEQRES   7 M  140  PRO GLY GLY LEU LYS LYS ILE PRO LEU GLU LYS MET LEU
SEQRES   8 M  140  ALA THR HIS PRO GLU ARG VAL LEU GLU HIS ALA VAL LYS
SEQRES   9 M  140  GLY MET LEU PRO LYS GLY PRO LEU GLY ARG ARG LEU PHE
SEQRES  10 M  140  LYS ARG LEU LYS VAL TYR ALA GLY PRO ASP HIS PRO HIS
SEQRES  11 M  140  GLN ALA GLN ARG PRO GLU LYS LEU GLU VAL
SEQRES   1 N  122  MET ILE GLN PRO GLN THR TYR LEU GLU VAL ALA ASP ASN
SEQRES   2 N  122  THR GLY ALA ARG LYS ILE MET CYS ILE ARG VAL LEU LYS
SEQRES   3 N  122  GLY SER ASN ALA LYS TYR ALA THR VAL GLY ASP VAL ILE
SEQRES   4 N  122  VAL ALA SER VAL LYS GLU ALA ILE PRO ARG GLY ALA VAL
SEQRES   5 N  122  LYS GLU GLY ASP VAL VAL LYS ALA VAL VAL VAL ARG THR
SEQRES   6 N  122  LYS LYS GLU ILE LYS ARG PRO ASP GLY SER ALA ILE ARG
SEQRES   7 N  122  PHE ASP ASP ASN ALA ALA VAL ILE ILE ASN ASN GLN LEU
SEQRES   8 N  122  GLU PRO ARG GLY THR ARG VAL PHE GLY PRO VAL ALA ARG
SEQRES   9 N  122  GLU LEU ARG GLU LYS GLY PHE MET LYS ILE VAL SER LEU
SEQRES  10 N  122  ALA PRO GLU VAL LEU
SEQRES   1 O  150  MET LYS LEU SER ASP LEU ARG PRO ASN PRO GLY ALA ASN
SEQRES   2 O  150  LYS ARG ARG LYS ARG VAL GLY ARG GLY PRO GLY SER GLY
SEQRES   3 O  150  HIS GLY LYS THR ALA THR ARG GLY HIS LYS GLY GLN LYS
SEQRES   4 O  150  SER ARG SER GLY GLY LEU LYS ASP PRO ARG ARG PHE GLU
SEQRES   5 O  150  GLY GLY ARG SER THR THR LEU MET ARG LEU PRO LYS ARG
SEQRES   6 O  150  GLY MET GLN GLY GLN VAL PRO GLY GLU ILE LYS ARG PRO
SEQRES   7 O  150  ARG TYR GLN GLY VAL ASN LEU LYS ASP LEU ALA ARG PHE
SEQRES   8 O  150  GLU GLY GLU VAL THR PRO GLU LEU LEU VAL ARG ALA GLY
SEQRES   9 O  150  LEU LEU LYS LYS GLY TYR ARG LEU LYS ILE LEU GLY GLU
SEQRES  10 O  150  GLY GLU ALA LYS PRO LEU LYS VAL VAL ALA HIS ALA PHE
SEQRES  11 O  150  SER LYS SER ALA LEU GLU LYS LEU LYS ALA ALA GLY GLY
SEQRES  12 O  150  GLU PRO VAL LEU LEU GLU ALA
SEQRES   1 P  141  MET LEU MET PRO ARG ARG MET LYS TYR ARG LYS GLN GLN
SEQRES   2 P  141  ARG GLY ARG LEU LYS GLY ALA THR LYS GLY GLY ASP TYR
SEQRES   3 P  141  VAL ALA PHE GLY ASP TYR GLY LEU VAL ALA LEU GLU PRO
SEQRES   4 P  141  ALA TRP ILE THR ALA GLN GLN ILE GLU ALA ALA ARG VAL
SEQRES   5 P  141  ALA MET VAL ARG HIS PHE ARG ARG GLY GLY LYS ILE PHE
SEQRES   6 P  141  ILE ARG ILE PHE PRO ASP LYS PRO TYR THR LYS LYS PRO
SEQRES   7 P  141  LEU GLU VAL ARG MET GLY LYS GLY LYS GLY ASN VAL GLU
SEQRES   8 P  141  GLY TYR VAL ALA VAL VAL LYS PRO GLY ARG VAL MET PHE
SEQRES   9 P  141  GLU VAL ALA GLY VAL THR GLU GLU GLN ALA MET GLU ALA
SEQRES  10 P  141  LEU ARG ILE ALA GLY HIS LYS LEU PRO ILE LYS THR LYS
SEQRES  11 P  141  ILE VAL ARG ARG ASP ALA TYR ASP GLU ALA GLN
SEQRES   1 0  118  MET ARG HIS LEU LYS SER GLY ARG LYS LEU ASN ARG HIS
SEQRES   2 0  118  SER SER HIS ARG LEU ALA LEU TYR ARG ASN GLN ALA LYS
SEQRES   3 0  118  SER LEU LEU THR HIS GLY ARG ILE THR THR THR VAL PRO
SEQRES   4 0  118  LYS ALA LYS GLU LEU ARG GLY PHE VAL ASP HIS LEU ILE
SEQRES   5 0  118  HIS LEU ALA LYS ARG GLY ASP LEU HIS ALA ARG ARG LEU
SEQRES   6 0  118  VAL LEU ARG ASP LEU GLN ASP VAL LYS LEU VAL ARG LYS
SEQRES   7 0  118  LEU PHE ASP GLU ILE ALA PRO ARG TYR ARG ASP ARG GLN
SEQRES   8 0  118  GLY GLY TYR THR ARG VAL LEU LYS LEU ALA GLU ARG ARG
SEQRES   9 0  118  ARG GLY ASP GLY ALA PRO LEU ALA LEU VAL GLU LEU VAL
SEQRES  10 0  118  GLU
SEQRES   1 Q  112  MET ALA ARG LEU THR ALA TYR GLU ARG ARG LYS PHE ARG
SEQRES   2 Q  112  VAL ARG ASN ARG ILE LYS ARG THR GLY ARG LEU ARG LEU
SEQRES   3 Q  112  SER VAL PHE ARG SER LEU LYS HIS ILE TYR ALA GLN ILE
SEQRES   4 Q  112  ILE ASP ASP GLU LYS GLY VAL THR LEU VAL SER ALA SER
SEQRES   5 Q  112  SER LEU ALA LEU LYS LEU LYS GLY ASN LYS THR GLU VAL
SEQRES   6 Q  112  ALA ARG GLN VAL GLY ARG ALA LEU ALA GLU LYS ALA LEU
SEQRES   7 Q  112  ALA LEU GLY ILE LYS GLN VAL ALA PHE ASP ARG GLY PRO
SEQRES   8 Q  112  TYR LYS TYR HIS GLY ARG VAL LYS ALA LEU ALA GLU GLY
SEQRES   9 Q  112  ALA ARG GLU GLY GLY LEU GLU PHE
SEQRES   1 R  146  MET ASN ARG GLY ALA LEU ILE LYS LEU VAL GLU SER ARG
SEQRES   2 R  146  TYR VAL ARG THR ASP LEU PRO GLU PHE ARG PRO GLY ASP
SEQRES   3 R  146  THR VAL ARG VAL SER TYR LYS VAL LYS GLU GLY ASN ARG
SEQRES   4 R  146  THR ARG ILE GLN ASP PHE GLU GLY ILE VAL ILE ARG ILE
SEQRES   5 R  146  ARG ARG ASN GLY PHE ASN THR THR PHE THR VAL ARG LYS
SEQRES   6 R  146  VAL SER TYR GLY VAL GLY VAL GLU ARG ILE PHE PRO LEU
SEQRES   7 R  146  HIS SER PRO LEU ILE GLN LYS ILE ASP ILE VAL GLN ARG
SEQRES   8 R  146  GLY ARG ALA ARG ARG ALA LYS LEU TYR PHE ILE ARG ASN
SEQRES   9 R  146  LEU SER ASP ARG GLU ILE ARG ARG LYS LEU ARG ALA ASP
SEQRES  10 R  146  ARG LYS ARG ILE ASP GLN ASP ARG ALA ALA GLU ARG ALA
SEQRES  11 R  146  ALA LYS GLU GLU ALA GLN LYS ALA GLN GLU PRO LYS ALA
SEQRES  12 R  146  SER GLN GLU
SEQRES   1 1  118  MET PRO ARG ALA LYS THR GLY VAL VAL ARG ARG ARG LYS
SEQRES   2 1  118  HIS LYS LYS ILE LEU LYS LEU ALA LYS GLY TYR TRP GLY
SEQRES   3 1  118  LEU ARG SER LYS SER PHE ARG LYS ALA ARG GLU THR LEU
SEQRES   4 1  118  PHE ALA ALA GLY ASN TYR ALA TYR ALA HIS ARG LYS ARG
SEQRES   5 1  118  ARG LYS ARG ASP PHE ARG ARG LEU TRP ILE VAL ARG ILE
SEQRES   6 1  118  ASN ALA ALA CYS ARG GLN HIS GLY LEU ASN TYR SER THR
SEQRES   7 1  118  PHE ILE HIS GLY LEU LYS LYS ALA GLY ILE GLU VAL ASP
SEQRES   8 1  118  ARG LYS ASN LEU ALA ASP LEU ALA VAL ARG GLU PRO GLN
SEQRES   9 1  118  VAL PHE ALA GLU LEU VAL GLU ARG ALA LYS ALA ALA GLN
SEQRES  10 1  118  GLY
SEQRES   1 2  101  MET PHE ALA ILE VAL LYS THR GLY GLY LYS GLN TYR ARG
SEQRES   2 2  101  VAL GLU PRO GLY LEU LYS LEU ARG VAL GLU LYS LEU ASP
SEQRES   3 2  101  ALA GLU PRO GLY ALA THR VAL GLU LEU PRO VAL LEU LEU
SEQRES   4 2  101  LEU GLY GLY GLU LYS THR VAL VAL GLY THR PRO VAL VAL
SEQRES   5 2  101  GLU GLY ALA SER VAL VAL ALA GLU VAL LEU GLY HIS GLY
SEQRES   6 2  101  ARG GLY LYS LYS ILE LEU VAL SER LYS PHE LYS ALA LYS
SEQRES   7 2  101  VAL GLN TYR ARG ARG LYS LYS GLY HIS ARG GLN PRO TYR
SEQRES   8 2  101  THR GLU LEU LEU ILE LYS GLU ILE ARG GLY
SEQRES   1 S  113  MET GLU ALA LYS ALA ILE ALA ARG TYR VAL ARG ILE SER
SEQRES   2 S  113  PRO ARG LYS VAL ARG LEU VAL VAL ASP LEU ILE ARG GLY
SEQRES   3 S  113  LYS SER LEU GLU GLU ALA ARG ASN ILE LEU ARG TYR THR
SEQRES   4 S  113  ASN LYS ARG GLY ALA TYR PHE VAL ALA LYS VAL LEU GLU
SEQRES   5 S  113  SER ALA ALA ALA ASN ALA VAL ASN ASN HIS ASP MET LEU
SEQRES   6 S  113  GLU ASP ARG LEU TYR VAL LYS ALA ALA TYR VAL ASP GLU
SEQRES   7 S  113  GLY PRO ALA LEU LYS ARG VAL LEU PRO ARG ALA ARG GLY
SEQRES   8 S  113  ARG ALA ASP ILE ILE LYS LYS ARG THR SER HIS ILE THR
SEQRES   9 S  113  VAL ILE LEU GLY GLU LYS HIS GLY LYS
SEQRES   1 T   96  MET LYS THR ALA TYR ASP VAL ILE LEU ALA PRO VAL LEU
SEQRES   2 T   96  SER GLU LYS ALA TYR ALA GLY PHE ALA GLU GLY LYS TYR
SEQRES   3 T   96  THR PHE TRP VAL HIS PRO LYS ALA THR LYS THR GLU ILE
SEQRES   4 T   96  LYS ASN ALA VAL GLU THR ALA PHE LYS VAL LYS VAL VAL
SEQRES   5 T   96  LYS VAL ASN THR LEU HIS VAL ARG GLY LYS LYS LYS ARG
SEQRES   6 T   96  LEU GLY ARG TYR LEU GLY LYS ARG PRO ASP ARG LYS LYS
SEQRES   7 T   96  ALA ILE VAL GLN VAL ALA PRO GLY GLN LYS ILE GLU ALA
SEQRES   8 T   96  LEU GLU GLY LEU ILE
SEQRES   1 U  110  MET ARG VAL LYS MET HIS VAL LYS LYS GLY ASP THR VAL
SEQRES   2 U  110  LEU VAL ALA SER GLY LYS TYR LYS GLY ARG VAL GLY LYS
SEQRES   3 U  110  VAL LYS GLU VAL LEU PRO LYS LYS TYR ALA VAL ILE VAL
SEQRES   4 U  110  GLU GLY VAL ASN ILE VAL LYS LYS ALA VAL ARG VAL SER
SEQRES   5 U  110  PRO LYS TYR PRO GLN GLY GLY PHE ILE GLU LYS GLU ALA
SEQRES   6 U  110  PRO LEU HIS ALA SER LYS VAL ARG PRO ILE CYS PRO ALA
SEQRES   7 U  110  CYS GLY LYS PRO THR ARG VAL ARG LYS LYS PHE LEU GLU
SEQRES   8 U  110  ASN GLY LYS LYS ILE ARG VAL CYS ALA LYS CYS GLY GLY
SEQRES   9 U  110  ALA LEU ASP THR GLU GLU
SEQRES   1 V  206  MET GLU TYR ARG LEU LYS ALA TYR TYR ARG GLU GLY GLU
SEQRES   2 V  206  LYS PRO SER ALA LEU ARG ARG ALA GLY LYS LEU PRO GLY
SEQRES   3 V  206  VAL MET TYR ASN ARG HIS LEU ASN ARG LYS VAL TYR VAL
SEQRES   4 V  206  ASP LEU VAL GLU PHE ASP LYS VAL PHE ARG GLN ALA SER
SEQRES   5 V  206  ILE HIS HIS VAL ILE VAL LEU GLU LEU PRO ASP GLY GLN
SEQRES   6 V  206  SER LEU PRO THR LEU VAL ARG GLN VAL ASN LEU ASP LYS
SEQRES   7 V  206  ARG ARG ARG ARG PRO GLU HIS VAL ASP PHE PHE VAL LEU
SEQRES   8 V  206  SER ASP GLU PRO VAL GLU MET TYR VAL PRO LEU ARG PHE
SEQRES   9 V  206  VAL GLY THR PRO ALA GLY VAL ARG ALA GLY GLY VAL LEU
SEQRES  10 V  206  GLN GLU ILE HIS ARG ASP ILE LEU VAL LYS VAL SER PRO
SEQRES  11 V  206  ARG ASN ILE PRO GLU PHE ILE GLU VAL ASP VAL SER GLY
SEQRES  12 V  206  LEU GLU ILE GLY ASP SER LEU HIS ALA SER ASP LEU LYS
SEQRES  13 V  206  LEU PRO PRO GLY VAL GLU LEU ALA VAL SER PRO GLU GLU
SEQRES  14 V  206  THR ILE ALA ALA VAL VAL PRO PRO GLU ASP VAL GLU LYS
SEQRES  15 V  206  LEU ALA GLU GLU ALA ALA ALA GLU VAL ALA GLU PRO GLU
SEQRES  16 V  206  VAL ILE LYS LYS GLY LYS GLU GLU GLU GLU GLU
SEQRES   1 3   85  MET ALA HIS LYS LYS GLY LEU GLY SER THR ARG ASN GLY
SEQRES   2 3   85  ARG ASP SER GLN ALA LYS ARG LEU GLY VAL LYS ARG TYR
SEQRES   3 3   85  GLU GLY GLN VAL VAL ARG ALA GLY ASN ILE LEU VAL ARG
SEQRES   4 3   85  GLN ARG GLY THR ARG PHE LYS PRO GLY LYS ASN VAL GLY
SEQRES   5 3   85  MET GLY ARG ASP PHE THR LEU PHE ALA LEU VAL ASP GLY
SEQRES   6 3   85  VAL VAL GLU PHE GLN ASP ARG GLY ARG LEU GLY ARG TYR
SEQRES   7 3   85  VAL HIS VAL ARG PRO LEU ALA
SEQRES   1 Z   98  MET SER LYS VAL CYS GLU ILE SER GLY LYS ARG PRO ILE
SEQRES   2 Z   98  VAL ALA ASN SER ILE GLN ARG ARG GLY LYS ALA LYS ARG
SEQRES   3 Z   98  GLU GLY GLY VAL GLY LYS LYS THR THR GLY ILE SER LYS
SEQRES   4 Z   98  ARG ARG GLN TYR PRO ASN LEU GLN LYS VAL ARG VAL ARG
SEQRES   5 Z   98  VAL ALA GLY GLN GLU ILE THR PHE ARG VAL ALA ALA SER
SEQRES   6 Z   98  HIS ILE PRO LYS VAL TYR GLU LEU VAL GLU ARG ALA LYS
SEQRES   7 Z   98  GLY LEU LYS LEU GLU GLY LEU SER PRO LYS GLU ILE LYS
SEQRES   8 Z   98  LYS GLU LEU LEU LYS LEU LEU
SEQRES   1 W   72  MET LYS LEU SER GLU VAL ARG LYS GLN LEU GLU GLU ALA
SEQRES   2 W   72  ARG LYS LEU SER PRO VAL GLU LEU GLU LYS LEU VAL ARG
SEQRES   3 W   72  GLU LYS LYS ARG GLU LEU MET GLU LEU ARG PHE GLN ALA
SEQRES   4 W   72  SER ILE GLY GLN LEU SER GLN ASN HIS LYS ILE ARG ASP
SEQRES   5 W   72  LEU LYS ARG GLN ILE ALA ARG LEU LEU THR VAL LEU ASN
SEQRES   6 W   72  GLU LYS ARG ARG GLN ASN ALA
SEQRES   1 X   60  MET PRO ARG LEU LYS VAL LYS LEU VAL LYS SER PRO ILE
SEQRES   2 X   60  GLY TYR PRO LYS ASP GLN LYS ALA ALA LEU LYS ALA LEU
SEQRES   3 X   60  GLY LEU ARG ARG LEU GLN GLN GLU ARG VAL LEU GLU ASP
SEQRES   4 X   60  THR PRO ALA ILE ARG GLY ASN VAL GLU LYS VAL ALA HIS
SEQRES   5 X   60  LEU VAL ARG VAL GLU VAL VAL GLU
SEQRES   1 4   71  MET LYS GLU GLY ILE HIS PRO LYS LEU VAL PRO ALA ARG
SEQRES   2 4   71  ILE ILE CYS GLY CYS GLY ASN VAL ILE GLU THR TYR SER
SEQRES   3 4   71  THR LYS PRO GLU ILE TYR VAL GLU VAL CYS SER LYS CYS
SEQRES   4 4   71  HIS PRO PHE TYR THR GLY GLN GLN ARG PHE VAL ASP THR
SEQRES   5 4   71  GLU GLY ARG VAL GLU ARG PHE GLN ARG ARG TYR GLY ASP
SEQRES   6 4   71  SER TYR ARG LYS GLY ARG
SEQRES   1 5   60  MET ALA LYS HIS PRO VAL PRO LYS LYS LYS THR SER LYS
SEQRES   2 5   60  ALA ARG ARG ASP ALA ARG ARG SER HIS HIS ALA LEU THR
SEQRES   3 5   60  PRO PRO THR LEU VAL PRO CYS PRO GLU CYS LYS ALA MET
SEQRES   4 5   60  LYS PRO PRO HIS THR VAL CYS PRO GLU CYS GLY TYR TYR
SEQRES   5 5   60  ALA GLY ARG LYS VAL LEU GLU VAL
SEQRES   1 6   54  MET ALA SER GLU VAL ARG ILE LYS LEU LEU LEU GLU CYS
SEQRES   2 6   54  THR GLU CYS LYS ARG ARG ASN TYR ALA THR GLU LYS ASN
SEQRES   3 6   54  LYS ARG ASN THR PRO ASN LYS LEU GLU LEU ARG LYS TYR
SEQRES   4 6   54  CYS PRO TRP CYS ARG LYS HIS THR VAL HIS ARG GLU VAL
SEQRES   5 6   54  LYS ILE
SEQRES   1 7   49  MET LYS ARG THR TRP GLN PRO ASN ARG ARG LYS ARG ALA
SEQRES   2 7   49  LYS THR HIS GLY PHE ARG ALA ARG MET ARG THR PRO GLY
SEQRES   3 7   49  GLY ARG LYS VAL LEU LYS ARG ARG ARG GLN LYS GLY ARG
SEQRES   4 7   49  TRP ARG LEU THR PRO ALA VAL ARG LYS ARG
SEQRES   1 8   65  MET PRO LYS MET LYS THR HIS LYS GLY ALA LYS LYS ARG
SEQRES   2 8   65  VAL LYS ILE THR ALA SER GLY LYS VAL VAL ALA MET LYS
SEQRES   3 8   65  THR GLY LYS ARG HIS LEU ASN TRP GLN LYS SER GLY LYS
SEQRES   4 8   65  GLU ILE ARG GLN LYS GLY ARG LYS PHE VAL LEU ALA LYS
SEQRES   5 8   65  PRO GLU ALA GLU ARG ILE LYS LEU LEU LEU PRO TYR GLU
HELIX    1   1 LYS D   68  VAL D   73  5                                   6
HELIX    2   2 ARG D  134  ILE D  136  5                                   3
HELIX    3   3 ASP D  200  ILE D  204  5                                   5
HELIX    4   4 LYS D  208  LEU D  215  1                                   8
HELIX    5   5 ASN F   29  ARG F   45  1                                  17
HELIX    6   6 PRO F  102  ARG F  119  1                                  18
HELIX    7   7 LYS F  135  GLU F  145  1                                  11
HELIX    8   8 ASN F  160  ASN F  169  1                                  10
HELIX    9   9 ALA F  177  LEU F  181  5                                   5
HELIX   10  10 ASN F  182  THR F  189  1                                   8
HELIX   11  11 LEU F  196  ILE F  206  1                                  11
HELIX   12  12 VAL G    5  GLU G   13  1                                   9
HELIX   13  13 GLU G   14  GLY G   24  1                                  11
HELIX   14  14 LEU G   43  LYS G   47  5                                   5
HELIX   15  15 ALA G   50  THR G   64  1                                  15
HELIX   16  16 ASP G   97  VAL G  109  1                                  13
HELIX   17  17 VAL G  109  ILE G  114  1                                   6
HELIX   18  18 GLU G  137  PHE G  141  5                                   5
HELIX   19  19 THR G  165  GLY G  177  1                                  13
HELIX   20  20 GLU H   58  VAL H   79  1                                  22
HELIX   21  21 LYS H  138  ALA H  150  1                                  13
HELIX   22  22 LYS K   22  TYR K   29  1                                   8
HELIX   23  23 LEU K   30  GLY K   34  5                                   5
HELIX   24  24 THR K   40  GLU K   73  1                                  34
HELIX   25  25 THR K   93  GLN K  104  1                                  12
HELIX   26  26 THR M   22  ARG M   35  1                                  14
HELIX   27  27 ASN M   56  ILE M   60  5                                   5
HELIX   28  28 LEU M   87  THR M   93  1                                   7
HELIX   29  29 PRO M   95  GLY M  105  1                                  11
HELIX   30  30 PRO M  111  LEU M  116  1                                   6
HELIX   31  31 ALA N  103  ARG N  107  5                                   5
HELIX   32  32 PHE N  111  ALA N  118  1                                   8
HELIX   33  33 ALA O   12  ARG O   16  5                                   5
HELIX   34  34 LEU O   85  ALA O   89  1                                   5
HELIX   35  35 GLU O   98  GLY O  104  1                                   7
HELIX   36  36 SER O  131  ALA O  140  1                                  10
HELIX   37  37 ALA P   44  PHE P   58  1                                  15
HELIX   38  38 THR P  110  LYS P  124  1                                  15
HELIX   39  39 HIS 0   13  LEU 0   29  1                                  17
HELIX   40  40 VAL 0   38  GLY 0   58  1                                  21
HELIX   41  41 ASP 0   59  GLN 0   71  1                                  13
HELIX   42  42 ASP 0   72  ASP 0   81  1                                  10
HELIX   43  43 ILE 0   83  ARG 0   88  5                                   6
HELIX   44  44 THR Q    5  LYS Q   11  1                                   7
HELIX   45  45 VAL Q   14  LYS Q   19  1                                   6
HELIX   46  46 ASN Q   61  LEU Q   80  1                                  20
HELIX   47  47 HIS Q   95  ALA Q  105  1                                  11
HELIX   48  48 ARG R    3  VAL R   10  1                                   8
HELIX   49  49 LEU R   99  ARG R  103  5                                   5
HELIX   50  50 GLU R  109  LEU R  114  1                                   6
HELIX   51  51 ASP R  117  GLU R  133  1                                  17
HELIX   52  52 VAL 1    8  ALA 1   21  1                                  14
HELIX   53  53 GLY 1   26  SER 1   31  1                                   6
HELIX   54  54 SER 1   31  GLY 1   73  1                                  43
HELIX   55  55 ASN 1   75  LYS 1   85  1                                  11
HELIX   56  56 GLU 1  102  ALA 1  116  1                                  15
HELIX   57  57 SER S   13  ARG S   25  1                                  13
HELIX   58  58 SER S   28  TYR S   38  1                                  11
HELIX   59  59 LYS S   41  ASN S   61  1                                  21
HELIX   60  60 SER T   14  ALA T   22  1                                   9
HELIX   61  61 THR T   35  LYS T   48  1                                  14
HELIX   62  62 SER U   70  VAL U   72  5                                   3
HELIX   63  63 LYS V   14  ALA V   21  1                                   8
HELIX   64  64 LEU V   41  SER V   52  1                                  12
HELIX   65  65 GLY 3   73  LEU 3   75  5                                   3
HELIX   66  66 HIS Z   66  GLU Z   75  1                                  10
HELIX   67  67 SER Z   86  LYS Z   91  1                                   6
HELIX   68  68 LYS Z   92  LEU Z   95  5                                   4
HELIX   69  69 SER W    4  ARG W   14  1                                  11
HELIX   70  70 PRO W   18  ILE W   41  1                                  24
HELIX   71  71 HIS W   48  GLN W   70  1                                  23
HELIX   72  72 PRO X   16  GLY X   27  1                                  12
HELIX   73  73 THR X   40  GLU X   48  1                                   9
HELIX   74  74 GLU 4   57  ASP 4   65  1                                   9
HELIX   75  75 SER 5   12  ARG 5   20  1                                   9
HELIX   76  76 SER 5   21  HIS 5   23  5                                   3
HELIX   77  77 ASN 7    8  HIS 7   16  1                                   9
HELIX   78  78 GLY 7   17  THR 7   24  1                                   8
HELIX   79  79 THR 7   24  GLY 7   38  1                                  15
HELIX   80  80 HIS 8    7  LYS 8   12  1                                   6
HELIX   81  81 ARG 8   42  ARG 8   46  5                                   5
HELIX   82  82 GLU 8   54  LEU 8   61  1                                   8
SHEET    1   A 2 LYS D   4  LYS D   5  0
SHEET    2   A 2 THR D  17  VAL D  18 -1  O  VAL D  18   N  LYS D   4
SHEET    1   B 2 LEU D  37  LYS D  38  0
SHEET    2   B 2 LEU D  61  TYR D  62 -1  O  TYR D  62   N  LEU D  37
SHEET    1   C 4 LYS D 102  ILE D 105  0
SHEET    2   C 4 ILE D  92  TYR D  97 -1  N  ALA D  93   O  ILE D 105
SHEET    3   C 4 ALA D  77  GLU D  83 -1  N  LYS D  78   O  HIS D  96
SHEET    4   C 4 GLN D 116  VAL D 117 -1  O  VAL D 117   N  ALA D  77
SHEET    1   D 4 ALA D 130  PRO D 132  0
SHEET    2   D 4 TYR D 190  VAL D 193 -1  O  ALA D 191   N  LEU D 131
SHEET    3   D 4 VAL D 141  GLU D 146 -1  N  GLU D 146   O  TYR D 190
SHEET    4   D 4 ALA D 153  LEU D 155 -1  O  LYS D 154   N  VAL D 145
SHEET    1   E 6 ALA D 130  PRO D 132  0
SHEET    2   E 6 TYR D 190  VAL D 193 -1  O  ALA D 191   N  LEU D 131
SHEET    3   E 6 VAL D 141  GLU D 146 -1  N  GLU D 146   O  TYR D 190
SHEET    4   E 6 ALA D 163  ARG D 168 -1  O  ALA D 163   N  VAL D 142
SHEET    5   E 6 TYR D 172  ARG D 176 -1  O  ILE D 174   N  GLY D 167
SHEET    6   E 6 LEU D 182  HIS D 186 -1  O  ARG D 183   N  LEU D 175
SHEET    1   F 4 LEU E   5  VAL E   7  0
SHEET    2   F 4 LEU E 195  ARG E 199 -1  O  VAL E 196   N  GLY E   6
SHEET    3   F 4 ARG E 101  THR E 107 -1  N  ASP E 103   O  ARG E 199
SHEET    4   F 4 ARG E 164  GLU E 171 -1  O  LEU E 170   N  VAL E 102
SHEET    1   G 2 PHE E 113  ALA E 114  0
SHEET    2   G 2 GLY E 158  HIS E 159 -1  O  GLY E 158   N  ALA E 114
SHEET    1   H 4 LEU F 123  VAL F 126  0
SHEET    2   H 4 ARG F 191  ASP F 195  1  O  MET F 194   N  LEU F 123
SHEET    3   H 4 VAL F 154  VAL F 157  1  N  VAL F 157   O  VAL F 193
SHEET    4   H 4 VAL F 173  VAL F 174  1  O  VAL F 174   N  VAL F 154
SHEET    1   I 5 ALA G  69  ARG G  72  0
SHEET    2   I 5 PRO G  87  LEU G  94 -1  O  ARG G  91   N  ALA G  69
SHEET    3   I 5 LEU G  34  GLN G  41 -1  N  GLN G  41   O  LEU G  90
SHEET    4   I 5 MET G 155  THR G 161 -1  O  ASP G 156   N  ASN G  40
SHEET    5   I 5 ASN G 130  LEU G 135 -1  N  LEU G 135   O  MET G 155
SHEET    1   J 2 LEU H 103  GLU H 104  0
SHEET    2   J 2 VAL H 114  VAL H 115 -1  O  VAL H 115   N  LEU H 103
SHEET    1   K 3 VAL K  18  ASP K  20  0
SHEET    2   K 3 LYS K   2  LEU K   5 -1  N  VAL K   3   O  VAL K  19
SHEET    3   K 3 ALA K  36  LEU K  38 -1  O  VAL K  37   N  ILE K   4
SHEET    1   L 2 GLY K 124  TYR K 126  0
SHEET    2   L 2 LEU K 140  VAL K 142 -1  O  LEU K 140   N  TYR K 126
SHEET    1   M 3 TRP M  13  ILE M  16  0
SHEET    2   M 3 PHE M  51  VAL M  54  1  O  VAL M  53   N  VAL M  14
SHEET    3   M 3 LEU M 120  VAL M 122  1  O  LYS M 121   N  VAL M  54
SHEET    1   N 2 ILE M  71  TYR M  75  0
SHEET    2   N 2 LEU M  82  PRO M  86 -1  O  ILE M  85   N  TYR M  72
SHEET    1   O 5 TYR N   7  GLU N   9  0
SHEET    2   O 5 ALA N  16  LEU N  25 -1  O  ILE N  19   N  LEU N   8
SHEET    3   O 5 VAL N  38  ALA N  46 -1  O  VAL N  40   N  ILE N  22
SHEET    4   O 5 VAL N  57  VAL N  62 -1  O  VAL N  58   N  ALA N  41
SHEET    5   O 5 ALA N  84  ILE N  87 -1  O  ILE N  87   N  LYS N  59
SHEET    1   P 7 ILE N  69  LYS N  70  0
SHEET    2   P 7 ALA N  76  PHE N  79 -1  O  ILE N  77   N  ILE N  69
SHEET    3   P 7 VAL R  70  PRO R  77 -1  O  ILE R  75   N  ALA N  76
SHEET    4   P 7 THR R  60  SER R  67 -1  N  LYS R  65   O  VAL R  72
SHEET    5   P 7 ARG R  41  ARG R  53 -1  N  ILE R  48   O  ARG R  64
SHEET    6   P 7 THR R  27  VAL R  34 -1  N  TYR R  32   O  GLN R  43
SHEET    7   P 7 ILE R  88  GLN R  90 -1  O  VAL R  89   N  THR R  27
SHEET    1   Q 3 GLN O  81  ASN O  84  0
SHEET    2   Q 3 LEU O 112  LEU O 115  1  O  LYS O 113   N  GLN O  81
SHEET    3   Q 3 ALA O 129  PHE O 130  1  O  ALA O 129   N  ILE O 114
SHEET    1   R 3 VAL P 102  MET P 103  0
SHEET    2   R 3 GLY P  33  VAL P  35 -1  N  LEU P  34   O  MET P 103
SHEET    3   R 3 ILE P 131  VAL P 132 -1  O  VAL P 132   N  GLY P  33
SHEET    1   S 3 ALA P  40  THR P  43  0
SHEET    2   S 3 TYR P  93  VAL P  97 -1  O  VAL P  97   N  ALA P  40
SHEET    3   S 3 LYS P  72  PRO P  73 -1  N  LYS P  72   O  VAL P  94
SHEET    1   T 2 LYS P  63  ILE P  64  0
SHEET    2   T 2 VAL P 106  ALA P 107 -1  O  ALA P 107   N  LYS P  63
SHEET    1   U 3 ARG 0  33  THR 0  37  0
SHEET    2   U 3 LEU 0 111  LEU 0 116 -1  O  VAL 0 114   N  ILE 0  34
SHEET    3   U 3 THR 0  95  LEU 0 100 -1  N  LEU 0  98   O  LEU 0 113
SHEET    1   V 3 ARG Q  25  ARG Q  30  0
SHEET    2   V 3 ILE Q  35  ASP Q  41 -1  O  TYR Q  36   N  PHE Q  29
SHEET    3   V 3 VAL Q  46  ALA Q  51 -1  O  LEU Q  48   N  ILE Q  39
SHEET    1   W 2 ALA 2   3  THR 2   7  0
SHEET    2   W 2 LYS 2  10  VAL 2  14 -1  O  LYS 2  10   N  THR 2   7
SHEET    1   X 4 LEU 2  18  VAL 2  22  0
SHEET    2   X 4 THR 2  92  ILE 2  96 -1  O  LEU 2  94   N  LEU 2  20
SHEET    3   X 4 VAL 2  57  GLY 2  63 -1  N  GLY 2  63   O  GLU 2  93
SHEET    4   X 4 GLU 2  34  LEU 2  35 -1  N  LEU 2  35   O  VAL 2  57
SHEET    1   Y 2 PHE 2  75  LYS 2  76  0
SHEET    2   Y 2 GLN 2  80  TYR 2  81 -1  O  GLN 2  80   N  LYS 2  76
SHEET    1   Z 3 GLU S   2  VAL S  10  0
SHEET    2   Z 3 ASP S  94  GLY S 108 -1  O  SER S 101   N  VAL S  10
SHEET    3   Z 3 TYR S  70  LEU S  86 -1  N  GLY S  79   O  THR S 100
SHEET    1  AA 4 ILE T   8  PRO T  11  0
SHEET    2  AA 4 LYS T  25  VAL T  30 -1  O  TRP T  29   N  ALA T  10
SHEET    3  AA 4 ARG T  76  GLN T  82 -1  O  VAL T  81   N  TYR T  26
SHEET    4  AA 4 LYS T  53  VAL T  59 -1  N  VAL T  59   O  ARG T  76
SHEET    1  AB 2 THR U  12  LEU U  14  0
SHEET    2  AB 2 VAL U  24  LYS U  26 -1  O  GLY U  25   N  VAL U  13
SHEET    1  AC 2 ALA U  36  VAL U  37  0
SHEET    2  AC 2 LEU U  67  HIS U  68 -1  O  LEU U  67   N  VAL U  37
SHEET    1  AD 2 LYS U  46  LYS U  47  0
SHEET    2  AD 2 PHE U  60  ILE U  61 -1  O  ILE U  61   N  LYS U  46
SHEET    1  AE 4 ASN V  34  ASP V  40  0
SHEET    2  AE 4 LYS V  23  TYR V  29 -1  N  MET V  28   O  ARG V  35
SHEET    3  AE 4 ARG V  82  VAL V  90  1  O  VAL V  90   N  TYR V  29
SHEET    4  AE 4 THR V  69  ASP V  77 -1  N  ASP V  77   O  ARG V  82
SHEET    1  AF 2 GLU V  97  TYR V  99  0
SHEET    2  AF 2 LEU V 125  LYS V 127 -1  O  VAL V 126   N  MET V  98
SHEET    1  AG 4 GLY 3  22  VAL 3  23  0
SHEET    2  AG 4 ILE 3  36  ARG 3  39 -1  O  ARG 3  39   N  GLY 3  22
SHEET    3  AG 4 LEU 3  59  ALA 3  61 -1  O  LEU 3  59   N  LEU 3  37
SHEET    4  AG 4 VAL 3  51  MET 3  53 -1  N  GLY 3  52   O  PHE 3  60
SHEET    1  AH 3 LYS 3  46  PRO 3  47  0
SHEET    2  AH 3 ARG 3  77  VAL 3  81  1  O  ARG 3  77   N  LYS 3  46
SHEET    3  AH 3 VAL 3  67  ASP 3  71 -1  N  GLN 3  70   O  TYR 3  78
SHEET    1  AI 2 ILE Z  13  GLY Z  22  0
SHEET    2  AI 2 LYS Z  32  GLN Z  42 -1  O  THR Z  35   N  GLN Z  19
SHEET    1  AJ 2 LEU Z  46  ARG Z  52  0
SHEET    2  AJ 2 GLU Z  57  ALA Z  63 -1  O  VAL Z  62   N  GLN Z  47
SHEET    1  AK 3 GLU X  34  GLU X  38  0
SHEET    2  AK 3 ARG X   3  LEU X   8 -1  N  LEU X   4   O  LEU X  37
SHEET    3  AK 3 VAL X  54  VAL X  59 -1  O  GLU X  57   N  LYS X   5
SHEET    1  AL 2 VAL 4  10  PRO 4  11  0
SHEET    2  AL 2 THR 4  24  TYR 4  25 -1  O  TYR 4  25   N  VAL 4  10
SHEET    1  AM 2 VAL 5  31  PRO 5  32  0
SHEET    2  AM 2 MET 5  39  LYS 5  40 -1  O  LYS 5  40   N  VAL 5  31
SHEET    1  AN 2 LEU 6  10  GLU 6  12  0
SHEET    2  AN 2 THR 6  23  LYS 6  25 -1  O  GLU 6  24   N  LEU 6  11
SHEET    1  AO 2 LYS 8  15  ILE 8  16  0
SHEET    2  AO 2 VAL 8  22  VAL 8  23 -1  O  VAL 8  23   N  LYS 8  15
SSBOND   1 CYS 4   16    CYS 4   36                          1555   1555  2.04
SSBOND   2 CYS 4   16    CYS 4   39                          1555   1555  2.05
SSBOND   3 CYS 4   18    CYS 4   36                          1555   1555  2.06
SSBOND   4 CYS 4   18    CYS 4   39                          1555   1555  2.07
SSBOND   5 CYS 4   36    CYS 4   39                          1555   1555  1.94
CISPEP   1 LYS D   35    PRO D   36          0        -0.55
CISPEP   2 THR E  146    PRO E  147          0         0.31
CISPEP   3 VAL H  125    PRO H  126          0         0.01
CISPEP   4 LYS K  131    PRO K  132          0         0.15
CISPEP   5 GLY M  125    PRO M  126          0         0.37
CISPEP   6 ASP O   47    PRO O   48          0         0.09
CISPEP   7 SER W   17    PRO W   18          0         0.17
CISPEP   8 THR 6   30    PRO 6   31          0         0.05
CRYST1  209.460  446.200  623.050  90.00  90.00  90.00 P 21 21 21    4
ORIGX1      1.000000  0.000000  0.000000        0.00000
ORIGX2      0.000000  1.000000  0.000000        0.00000
ORIGX3      0.000000  0.000000  1.000000        0.00000
SCALE1      0.004774  0.000000  0.000000        0.00000
SCALE2      0.000000  0.002241  0.000000        0.00000
SCALE3      0.000000  0.000000  0.001605        0.00000
      
PROCHECK
Go to PROCHECK summary
 References