UniProt functional annotation for P12735

UniProt code: P12735.

Organism: Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui).
Taxonomy: Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Haloarcula.
 
Function: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly (By similarity).
 
Function: Makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit.
 
Function: Forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L22. Contacts the macrolide antibiotic spiramycin in the polypeptide exit tunnel.
 
Subunit: Part of the 50S ribosomal subunit. Interacts weakly with proteins L18e, L24 and L37e. Has been cross-linked to L18e.
Similarity: Belongs to the ribosomal protein L4P family.

Annotations taken from UniProtKB at the EBI.