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PDBsum entry 3hup
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Immune system
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PDB id
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3hup
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Contents |
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* Residue conservation analysis
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PDB id:
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Immune system
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Title:
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High-resolution structure of the extracellular domain of human cd69
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Structure:
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Early activation antigen cd69. Chain: a, b. Fragment: extracellular domain, unp residues 70-199. Synonym: early t-cell activation antigen p60, gp32/28, leu-23, mlr-3, ea1, bl-ac/p26, activation inducer molecule, aim. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: cd69. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.37Å
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R-factor:
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0.135
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R-free:
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0.184
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Authors:
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P.Kolenko,J.Dohnalek,T.Skalova,J.Hasek,J.Duskova,O.Vanek,K.Bezouska
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Key ref:
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P.Kolenko
et al.
(2009).
The high-resolution structure of the extracellular domain of human CD69 using a novel polymer.
Acta Crystallogr Sect F Struct Biol Cryst Commun,
65,
1258-1260.
PubMed id:
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Date:
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15-Jun-09
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Release date:
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15-Dec-09
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PROCHECK
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Headers
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References
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Q07108
(CD69_HUMAN) -
Early activation antigen CD69 from Homo sapiens
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Seq:
Struc:
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199 a.a.
121 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Acta Crystallogr Sect F Struct Biol Cryst Commun
65:1258-1260
(2009)
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PubMed id:
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The high-resolution structure of the extracellular domain of human CD69 using a novel polymer.
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P.Kolenko,
T.Skálová,
O.Vanek,
A.Stepánková,
J.Dusková,
J.Hasek,
K.Bezouska,
J.Dohnálek.
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ABSTRACT
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The structure of the extracellular domain of human CD69 has been determined by
single-crystal X-ray diffraction. The structure refined to 1.37 A resolution
provides further details of the overall structure and the asymmetric interface
between the monomers in the native dimer. The protein was crystallized using
di[poly(ethylene glycol)] adipate, which also served as a cryoprotectant. This
is the first report of a crystal structure determined using crystals grown with
this polymer.
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Links
