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UniProt functional annotation for Q8IZX4 | ||
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| UniProt code: Q8IZX4. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. {ECO:0000269|PubMed:12217962}. |
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| Subunit: | |
Can bind directly to TATA-box binding protein (TBP). Interacts (via bromo domains) with acetylated lysine residues on the N-terminus of histone H1.4, H2A, H2B, H3 and H4 (in vitro). {ECO:0000269|PubMed:12217962, ECO:0000269|PubMed:22464331}. |
| Subcellular location: | |
Nucleus {ECO:0000250}. |
| Tissue specificity: | |
Testis specific, expressed apparently in germ cells. |
| Similarity: | |
Belongs to the TAF1 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.