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PDBsum entry 3hmh
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Transcription
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PDB id
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3hmh
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Contents |
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* Residue conservation analysis
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PDB id:
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Transcription
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Title:
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Crystal structure of the second bromodomain of human tbp-associated factor RNA polymerase 1-like (taf1l)
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Structure:
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Transcription initiation factor tfiid 210 kda subunit. Chain: a. Fragment: bromodomain, unp residues 1523-1651. Synonym: taf1l, tbp-associated factor 210 kda, taf(ii)210, tbp- associated factor 1-like. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: taf1l. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.05Å
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R-factor:
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0.185
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R-free:
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0.252
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Authors:
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P.Filippakopoulos,S.Picaud,T.Keates,Y.Zhang,A.C.W.Pike,F.Von Delft, C.H.Arrowsmith,A.Edwards,J.Weigelt,C.Bountra,S.Knapp,Structural Genomics Consortium (Sgc)
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Key ref:
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P.Filippakopoulos
et al.
(2012).
Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell,
149,
214-231.
PubMed id:
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Date:
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29-May-09
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Release date:
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23-Jun-09
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PROCHECK
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Headers
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References
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Q8IZX4
(TAF1L_HUMAN) -
Transcription initiation factor TFIID subunit 1-like from Homo sapiens
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Seq:
Struc:
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1826 a.a.
139 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 9 residue positions (black
crosses)
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Cell
149:214-231
(2012)
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PubMed id:
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Histone recognition and large-scale structural analysis of the human bromodomain family.
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P.Filippakopoulos,
S.Picaud,
M.Mangos,
T.Keates,
J.P.Lambert,
D.Barsyte-Lovejoy,
I.Felletar,
R.Volkmer,
S.Müller,
T.Pawson,
A.C.Gingras,
C.H.Arrowsmith,
S.Knapp.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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C.A.Musselman,
M.E.Lalonde,
J.Côté,
and
T.G.Kutateladze
(2012).
Perceiving the epigenetic landscape through histone readers.
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Nat Struct Mol Biol,
19,
1218-1227.
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
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Links
