PDBsum entry 3hko

Transferase

PDB id: 3hko

Contents

Protein chain

319 a.a. *

Ligands

GOL

ANP

Metals

_MG

_ZN

Waters ×123

* Residue conservation analysis

PDB id:

3hko

Name:

Transferase

Title:

Crystal structure of a cdpk kinase domain from cryptosporidium parvum, cgd7_40

Structure:

Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like ef hands. Chain: a. Fragment: kinase domain. Engineered: yes

Source:

Cryptosporidium parvum iowa ii. Organism_taxid: 353152. Gene: cgd7_40. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.80Å R-factor: 0.204 R-free: 0.246

Authors:

A.K.Wernimont,A.Hutchinson,G.Wasney,M.Vedadi,F.Mackenzie, I.Kozieradzki,D.Cossar,J.Weigelt,A.M.Edwards,C.H.Arrowsmith, C.Bountra,A.Botchkarev,R.Hui,J.D.Artz,M.Amani,Structural Genomics Consortium (Sgc)

Key ref:

A.K.Wernimont et al. Crystal structure of a cdpk kinase domain from cryptosporidium parvum, Cgd7_40. To be published, .

Date:

25-May-09 Release date: 02-Jun-09

Protein chain

Q5CZ29  (Q5CZ29_CRYPI) -  Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands (Fragment) from Cryptosporidium parvum (strain Iowa II)

Seq: 824 a.a.

Struc: 319 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)