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PDBsum entry 3h8m
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protein Protein-protein interface(s) links
Transferase PDB id
3h8m

 

 

 

 

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Contents
Protein chains
71 a.a. *
79 a.a. *
Waters ×55
* Residue conservation analysis
PDB id:
3h8m
Name: Transferase
Title: Sam domain of human ephrin type-a receptor 7 (epha7)
Structure: Ephrin type-a receptor 7. Chain: a, b. Fragment: sam domain, residues 919-990. Synonym: tyrosine-protein kinase receptor ehk-3, eph homology kinase 3, receptor protein-tyrosine kinase hek11. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ehk3, epha7, hek11. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
2.10Å     R-factor:   0.199     R-free:   0.228
Authors: J.R.Walker,L.Yermekbayeva,C.Butler-Cole,C.Bountra,J.Weigelt, C.H.Arrowsmith,A.M.Edwards,A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
Key ref: J.R.Walker et al. Sam domain of human ephrin type-A receptor 7 (epha7). To be published, .
Date:
29-Apr-09     Release date:   26-May-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Q15375  (EPHA7_HUMAN) -  Ephrin type-A receptor 7 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		998 a.a.
71 a.a.
Protein chain
Q15375  (EPHA7_HUMAN) -  Ephrin type-A receptor 7 from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		998 a.a.
79 a.a.*
Key:    Secondary structure  CATH domain
* PDB and UniProt seqs differ at 5 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: Chains A, B: E.C.2.7.10.1  - receptor protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
 + ATP
 = O-phospho-L-tyrosyl-[protein]
 + ADP
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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