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PDBsum entry 3h0h

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protein ligands links
Transferase PDB id
3h0h
Jmol PyMol
Contents
Protein chain
63 a.a. *
Ligands
PG4
Waters ×35
* Residue conservation analysis
PDB id:
3h0h
Name: Transferase
Title: Human fyn sh3 domain r96i mutant, crystal form i
Structure: Proto-oncogene tyrosine-protein kinase fyn. Chain: a. Fragment: sh3 domain, unp residues 73-142. Synonym: fyn tyrosine kinase, p59-fyn, protooncogene syn, s engineered: yes. Mutation: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fyn. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.76Å     R-factor:   0.170     R-free:   0.222
Authors: C.Dumas,M.-P.Strub,S.T.Arold
Key ref: A.Lugari et al. Sh3 domain specificity. To be published, .
Date:
09-Apr-09     Release date:   21-Apr-10    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P06241  (FYN_HUMAN) -  Tyrosine-protein kinase Fyn
Seq:
Struc:
 
Seq:
Struc:
537 a.a.
63 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.2  - Non-specific protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
ATP
+ [protein]-L-tyrosine
= ADP
+ [protein]-L-tyrosine phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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